Arsenic Trioxide



Indications and Reactions:

Role Indications Reactions
Primary
Acute Promyelocytic Leukaemia 32.2%
Myelodysplastic Syndrome 32.2%
Acute Myeloid Leukaemia 14.4%
Glioblastoma Multiforme 3.3%
Myelofibrosis 3.3%
Lung Neoplasm Malignant 2.8%
Multiple Myeloma 2.2%
Anaplastic Astrocytoma 1.7%
Glioblastoma 1.1%
Small Cell Lung Cancer 1.1%
Small Cell Lung Cancer Stage Unspecified 1.1%
Adult T-cell Lymphoma/leukaemia 0.6%
Brain Oedema 0.6%
Brain Stem Glioma 0.6%
Metastatic Renal Cell Carcinoma 0.6%
Non-small Cell Lung Cancer 0.6%
Pain 0.6%
Prophylaxis 0.6%
Retinoic Acid Syndrome 0.6%
White Blood Cell Count Decreased 16.7%
Pyrexia 6.7%
Renal Failure Acute 6.7%
Vomiting 6.7%
White Blood Cell Count Increased 6.7%
Pneumonia 5.0%
Respiratory Failure 5.0%
Sinus Tachycardia 5.0%
Ventricular Extrasystoles 5.0%
Anaphylactic Reaction 3.3%
Bone Marrow Necrosis 3.3%
Cerebral Haemorrhage 3.3%
Cough 3.3%
Death 3.3%
Mitochondrial Myopathy 3.3%
Pleural Effusion 3.3%
Red Blood Cell Abnormality 3.3%
Renal Failure 3.3%
Respiratory Depression 3.3%
Sepsis 3.3%
Secondary
Acute Promyelocytic Leukaemia 29.1%
Myelodysplastic Syndrome 26.4%
Acute Myeloid Leukaemia 17.3%
Multiple Myeloma 6.7%
Malignant Glioma 4.8%
Product Used For Unknown Indication 3.2%
Myelofibrosis 2.7%
Pyrexia 2.7%
Anxiety Disorder 1.1%
Pain 1.1%
Pneumocystis Jiroveci Pneumonia 1.1%
Myeloid Leukaemia 0.8%
Drug Use For Unknown Indication 0.5%
Glioblastoma Multiforme 0.5%
Nausea 0.5%
Oral Herpes 0.5%
Depression 0.3%
Drug Withdrawal Syndrome 0.3%
Mental Disorder 0.3%
Prophylaxis 0.3%
Pyrexia 14.3%
White Blood Cell Count Decreased 13.0%
Pneumonia 9.1%
Electrocardiogram Qt Prolonged 6.5%
Neutropenia 6.5%
Anaphylactic Reaction 5.2%
Sepsis 5.2%
Thrombocythaemia 5.2%
Leukopenia 3.9%
Renal Failure Acute 3.9%
Thrombocytopenia 3.9%
Bacterial Sepsis 2.6%
Hepatic Enzyme Increased 2.6%
Herpes Zoster 2.6%
Hypophosphataemia 2.6%
Melaena 2.6%
Off Label Use 2.6%
Pancreatic Carcinoma 2.6%
Pericardial Effusion 2.6%
Protein Total Increased 2.6%
Concomitant
Plasma Cell Myeloma 31.1%
Acute Promyelocytic Leukaemia 27.9%
Body Temperature Increased 8.2%
Acute Myeloid Leukaemia 6.6%
Arthralgia 4.9%
Pyrexia 4.9%
Anxiety Disorder 3.3%
Chloroma 3.3%
Myelodysplastic Syndrome 3.3%
Chronic Myeloid Leukaemia 1.6%
Metastases To Meninges 1.6%
Pre-existing Disease 1.6%
Product Used For Unknown Indication 1.6%
Febrile Neutropenia 11.1%
Infusion Related Reaction 11.1%
Neuropathy Peripheral 11.1%
Supraventricular Tachycardia 11.1%
White Blood Cell Count Increased 11.1%
Abdominal Pain 5.6%
Bronchiectasis 5.6%
Leukaemia Recurrent 5.6%
Mitral Valve Incompetence 5.6%
Obsessive-compulsive Disorder 5.6%
Renal Impairment 5.6%
Retinoic Acid Syndrome 5.6%
Sepsis 5.6%
Interacting
Product Used For Unknown Indication 41.2%
Anxiety Disorder 17.6%
Pyrexia 11.8%
Acute Promyelocytic Leukaemia 8.8%
Bipolar Disorder 2.9%
Generalised Anxiety Disorder 2.9%
Major Depression 2.9%
Mental Disorder 2.9%
Obsessive-compulsive Disorder 2.9%
Panic Disorder 2.9%
Pulmonary Embolism 2.9%
Drug Interaction 66.7%
Anxiety 16.7%
Neutropenia 16.7%