Aldurazyme



Indications and Reactions:

Role Indications Reactions
Primary
Mucopolysaccharidosis I 64.3%
Product Used For Unknown Indication 18.1%
Mucopolysaccharidosis 11.4%
Premedication 2.0%
Mucopolysaccharidosis Ih 1.6%
Bone Marrow Transplant 0.3%
Epilepsy 0.3%
Mucopolysaccharidosis Ih/s 0.3%
Pain 0.3%
Spinal Cord Compression 0.3%
Bone Marrow Conditioning Regimen 0.2%
Cardiac Valve Disease 0.2%
Neck Pain 0.2%
Allogenic Bone Marrow Transplantation Therapy 0.1%
Anticoagulant Therapy 0.1%
Drug Therapy 0.1%
Drug Use For Unknown Indication 0.1%
Glycogen Storage Disease Type Ii 0.1%
Immunosuppressant Drug Therapy 0.1%
Infusion 0.1%
Pneumonia 12.8%
Death 9.5%
Respiratory Failure 9.5%
Vomiting 9.5%
Urticaria 5.9%
Respiratory Distress 5.2%
Cardiac Failure 4.6%
Weight Decreased 4.3%
Pyrexia 3.9%
Sepsis 3.9%
Spinal Cord Compression 3.9%
Mucopolysaccharidosis I 3.3%
Stem Cell Transplant 3.3%
Tachycardia 3.3%
Upper Respiratory Tract Infection 3.3%
Cardiopulmonary Failure 3.0%
Dyspnoea 3.0%
Bronchopneumonia 2.6%
Infusion Related Reaction 2.6%
Sleep Apnoea Syndrome 2.6%
Secondary
Mucopolysaccharidosis I 72.2%
Product Used For Unknown Indication 8.7%
Stem Cell Transplant 7.0%
Mucopolysaccharidosis 3.5%
Mucopolysaccharidosis Ih 3.5%
Premedication 2.6%
Mucopolysaccharidosis Ih/s 1.7%
Anticoagulant Therapy 0.9%
Urinary Glycosaminoglycans Increased 30.0%
Urticaria 12.0%
Pneumonia 6.0%
Wheezing 6.0%
Multi-organ Failure 4.0%
Oxygen Saturation Decreased 4.0%
Respiratory Failure 4.0%
Restlessness 4.0%
Staphylococcal Sepsis 4.0%
Sudden Death 4.0%
Vomiting 4.0%
Dyspnoea 2.0%
Laryngeal Oedema 2.0%
Pneumonia Viral 2.0%
Pregnancy 2.0%
Premature Labour 2.0%
Pulmonary Hypertension 2.0%
Pyrexia 2.0%
Renal Impairment 2.0%
Sepsis 2.0%
Concomitant
Bone Marrow Transplant 25.0%
Respiratory Disorder 25.0%
Bone Marrow Conditioning Regimen 12.5%
Growth Hormone Deficiency 12.5%
Mucopolysaccharidosis I 12.5%
Stem Cell Transplant 12.5%
Erythema Multiforme 40.0%
Lymphoproliferative Disorder 20.0%
Multi-organ Failure 20.0%
Osteochondrosis 20.0%