| Primary |
| Factor Viii Deficiency |
33.4% |
| Haemophilia |
16.6% |
| Product Used For Unknown Indication |
9.3% |
| Prophylaxis |
7.0% |
| Drug Use For Unknown Indication |
6.5% |
| Cerebral Haemorrhage |
4.4% |
| Haemorrhage |
3.7% |
| Haemorrhage Prophylaxis |
2.4% |
| Factor Viii Inhibition |
2.3% |
| Haemarthrosis |
2.1% |
| Immunomodulatory Therapy |
1.9% |
| Pain |
1.9% |
| Immune Tolerance Induction |
1.6% |
| Haemostasis |
1.5% |
| Hemophilia A |
1.3% |
| Immune Enhancement Therapy |
1.1% |
| Arthralgia |
0.8% |
| Haematoma |
0.8% |
| Haemophilic Arthropathy |
0.6% |
| Haemorrhage Intracranial |
0.6% |
|
| Factor Viii Inhibition |
37.6% |
| Haemorrhage |
10.5% |
| Haemarthrosis |
8.0% |
| Death |
4.6% |
| Device Related Infection |
4.2% |
| Muscle Haemorrhage |
4.2% |
| Coagulation Factor Viii Level Decreased |
3.4% |
| Road Traffic Accident |
3.0% |
| Drug Ineffective |
2.5% |
| Joint Swelling |
2.5% |
| Cerebral Haemorrhage |
2.1% |
| Head Injury |
2.1% |
| Hepatitis C |
2.1% |
| Liver Function Test Abnormal |
2.1% |
| Pyrexia |
2.1% |
| Subdural Haematoma |
2.1% |
| Vomiting |
2.1% |
| Haemorrhage Intracranial |
1.7% |
| Urticaria |
1.7% |
| Accident |
1.3% |
|
| Secondary |
| Factor Viii Deficiency |
23.1% |
| Prophylaxis |
13.5% |
| Pain |
13.4% |
| Haemophilia |
10.8% |
| Haemorrhage |
8.6% |
| Antibiotic Therapy |
6.6% |
| Product Used For Unknown Indication |
2.9% |
| Immunomodulatory Therapy |
2.7% |
| Subdural Haematoma |
2.4% |
| Haemorrhage Prophylaxis |
2.0% |
| Immune Enhancement Therapy |
1.9% |
| Factor Viii Inhibition |
1.7% |
| Immune Tolerance Induction |
1.5% |
| Surgery |
1.5% |
| Haemostasis |
1.4% |
| Drug Use For Unknown Indication |
1.4% |
| Haemarthrosis |
1.3% |
| Infection Prophylaxis |
1.2% |
| Knee Operation |
1.1% |
| Haemophilic Arthropathy |
1.0% |
|
| Drug Level Below Therapeutic |
20.6% |
| Factor Viii Inhibition |
16.0% |
| Haemarthrosis |
9.1% |
| Haemorrhage |
8.2% |
| Increased Tendency To Bruise |
6.9% |
| Muscle Haemorrhage |
6.1% |
| Subdural Haematoma |
4.4% |
| Vomiting |
3.7% |
| Oedema Peripheral |
3.5% |
| Medication Error |
3.4% |
| Coagulation Factor Viii Level Decreased |
3.2% |
| Joint Swelling |
3.1% |
| Device Related Infection |
2.4% |
| Hepatitis B Surface Antigen Positive |
2.2% |
| Drug Effect Decreased |
1.7% |
| Drug Ineffective |
1.2% |
| Laceration |
1.1% |
| Liver Function Test Abnormal |
1.1% |
| Staphylococcal Sepsis |
1.1% |
| Throat Irritation |
1.1% |
|
| Concomitant |
| Hiv Infection |
35.5% |
| Product Used For Unknown Indication |
11.8% |
| Diabetes Mellitus |
7.9% |
| Haemophilia |
7.3% |
| Drug Use For Unknown Indication |
6.4% |
| Factor Viii Deficiency |
6.4% |
| Hepatitis C |
4.7% |
| Hypertension |
4.7% |
| Diarrhoea |
2.2% |
| Panic Disorder |
2.2% |
| Acquired Immunodeficiency Syndrome |
1.7% |
| Insomnia |
1.7% |
| Prophylaxis |
1.5% |
| Reflux Oesophagitis |
1.5% |
| Renal Failure Acute |
0.9% |
| Abdominal Pain Upper |
0.7% |
| Epididymitis |
0.7% |
| Gastrooesophageal Reflux Disease |
0.7% |
| Prophylaxis Against Gastrointestinal Ulcer |
0.7% |
| Pruritus |
0.7% |
|
| Hyperlipidaemia |
12.1% |
| Pancreatic Carcinoma |
10.3% |
| Factor Viii Inhibition |
8.6% |
| Hepatitis C |
8.6% |
| Platelet Count Decreased |
6.9% |
| Pyrexia |
6.9% |
| Drug Ineffective |
5.2% |
| Haemorrhage |
5.2% |
| Reflux Oesophagitis |
5.2% |
| Haematology Test Abnormal |
3.4% |
| Intra-abdominal Haemorrhage |
3.4% |
| Renal Haemorrhage |
3.4% |
| Renal Tubular Disorder |
3.4% |
| Synovial Cyst |
3.4% |
| Vision Blurred |
3.4% |
| White Blood Cell Count Decreased |
3.4% |
| Cerebral Infarction |
1.7% |
| Dysgeusia |
1.7% |
| Gastric Ulcer |
1.7% |
| Headache |
1.7% |
|
