Velcade combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Multiple Myeloma Hospitalization 8/1/2005 71 Male 12/29/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 4/1/2005 63 Male 1/6/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious Male 150 lb 1/10/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 6/16/2004 54 Female 1/6/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 5/26/2004 54 Female 1/6/2006 Physician United States
Primary
Concomitant
White Blood Cell Scan Other Serious 6/4/2004 54 Female 1/6/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 7/10/2004 54 Female 1/6/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 8/1/2004 54 Female 1/6/2006 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 1/19/2006 68 Male 181 lb 1/19/2006 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 1/24/2005 44 Male 1/18/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 5/1/2005 76 Female 2/3/2006 Physician Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2005 Female 141 lb 2/2/2006 Physician Germany
Primary
Concomitant
Respiratory Alkalosis Other Serious 9/29/2005 60 Female 1/27/2006 France
Primary
Concomitant
Pain In Jaw Other Serious 12/22/2005 81 Male 196 lb 2/10/2006 United States
Primary
Concomitant
Thrombocytopenia Death 9/1/2005 57 Female 146 lb 2/6/2006 Physician United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 9/1/2005 81 Male 196 lb 2/17/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 12/1/2003 52 Female 2/18/2006 United States
Primary
Concomitant
Toothache Other Serious 9/1/2005 81 Male 196 lb 2/25/2006 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 8/1/2005 63 Female 141 lb 3/1/2006 Physician Germany
Primary
Secondary
Concomitant
Stem Cell Transplant Hospitalization 1/1/2005 76 Male 3/1/2006 France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2004 53 Male 3/2/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2005 80 Male 3/2/2006 United States
Primary
Concomitant
Pyrexia Death 65 Male 3/6/2006 Denmark
Primary
Concomitant
Sepsis Hospitalization 2/28/2005 55 Male 276 lb 2/27/2006 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Transiently Other Serious 4/15/2005 76 Male 209 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/28/2005 49 Female 3/17/2006 Physician United States
Primary
Concomitant
Surgery Hospitalization 5/1/2001 60 Male 3/29/2006 Physician Austria
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/1/2003 52 Female 4/12/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 11/18/2004 42 Male 3/31/2006 Other Health Professional Czech Republic
Primary
Concomitant
Weight Decreased Life Threatening 10/10/2004 49 Female 104 lb 3/29/2006 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2005 Female 123 lb 4/13/2006 Physician Australia
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 1/19/2006 68 Male 181 lb 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/2/2006 54 Female 4/10/2006 Physician Germany
Primary
Secondary
Concomitant
Oligomenorrhoea Other Serious 4/20/2006 Female 143 lb 4/21/2006 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Required Intervention 12/29/2005 49 Female 123 lb 4/21/2006 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 9/25/2005 76 Male 195 lb 2/17/2006 Physician United States
Primary
Concomitant
Pancreatitis Other Serious 63 Male 250 lb 2/17/2006 Physician United States
Primary
Concomitant
Oedema Peripheral 53 Male 322 lb 2/17/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 10/1/2004 73 Male 182 lb 2/17/2006 Consumer United States
Primary
Concomitant
Palpitations 44 Female 2/17/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 1/1/2005 65 Female 200 lb 2/17/2006 Consumer United States
Primary
Concomitant
Neuropathy Peripheral 1/1/2005 60 Male 189 lb 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/20/2005 48 Male 130 lb 2/17/2006 Physician United States
Primary
Concomitant
Neuropathy Hospitalization 9/10/2005 71 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased 1/17/2006 47 Male 216 lb 2/17/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 1/1/2005 73 Male 147 lb 2/17/2006 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2004 Female 5/5/2006 United States
Primary
Concomitant
Swelling Other Serious 4/1/2006 83 Female 5/5/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 2/4/2005 77 Male 183 lb 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 5/4/2004 85 Male 5/11/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2004 80 Female 5/15/2006 Physician Spain
Primary
Concomitant
Tooth Disorder Other Serious 7/1/2005 63 Female 143 lb 5/17/2006 Germany
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2004 59 Male 5/18/2006 Norway
Primary
Concomitant
Thrombocytopenia Other Serious 5/2/2006 Male 199 lb 5/3/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2004 59 Male 5/23/2006 Norway
Primary
Concomitant
Retinal Artery Occlusion Other Serious 5/1/2006 50 Female 170 lb 5/23/2006 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 3/1/2001 56 Female 259 lb 6/1/2006 United States
Primary
Secondary
Concomitant
Toothache Other Serious 78 Male 6/1/2006 Physician Brazil
Primary
Concomitant
Osteonecrosis Other Serious 62 Male 150 lb 6/5/2006 United States
Primary
Concomitant
Pregnancy Other Serious 4/20/2006 36 Female 143 lb 5/17/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 1/1/2004 77 Female 6/9/2006 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 12/1/2002 53 Male 5/25/2006 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 9/20/2005 65 Male 182 lb 6/8/2006 Physician United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/22/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 6/30/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 2/4/2006 80 Male 163 lb 5/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Disability 10/5/2005 52 Male 5/24/2006 Physician United States
Primary
Concomitant
Headache 1/1/2006 Male 5/24/2006 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 1/11/2005 70 Female 159 lb 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Syncope Hospitalization 1/30/2006 65 Female 171 lb 5/24/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2003 61 Male 7/25/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2006 71 Female 7/28/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 71 Female 7/28/2006 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/19/2004 47 Female 7/25/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 1/1/2005 74 Female 172 lb 7/11/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 12/27/2005 82 8/18/2006 United States
Primary
Concomitant
Appendicitis 8/13/2006 Female 153 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2006 55 Female 209 lb 9/6/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2006 77 Female 120 lb 9/13/2006 Physician United States
Primary
Secondary
Swelling Other Serious 12/27/2005 82 Male 9/25/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2006 71 Female 9/27/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Hospitalization 12/5/2005 Male 163 lb 9/29/2006 Physician Australia
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2005 62 Male 152 lb 10/4/2006 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 46 Female 150 lb 10/5/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/15/2006 36 Male 197 lb 10/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2006 67 Female 10/12/2006 Physician United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 6/6/2006 54 Female 117 lb 10/24/2006 Physician Germany
Primary
Concomitant
Pleuritic Pain Hospitalization 8/19/2006 61 Female 161 lb 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/3/2006 77 Female 120 lb 10/30/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/20/2006 62 Female 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/5/2006 59 Female 207 lb 11/6/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Swelling Other Serious 4/1/2006 83 Female 11/21/2006 United States
Primary
Concomitant
Vomiting Hospitalization 6/15/2006 36 Male 197 lb 11/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/5/2005 Male 163 lb 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/3/2006 77 Female 120 lb 11/14/2006 Physician United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 9/9/2006 83 Female 164 lb 11/28/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2004 71 Male 160 lb 11/22/2006 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 12/7/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 56 Female 12/7/2006 United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/23/2006 72 Female 100 lb 12/12/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2003 79 Female 11/30/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/3/2006 77 Female 120 lb 12/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/23/2006 Female 100 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/26/2006 66 Female 158 lb 12/8/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2003 79 Female 153 lb 12/15/2006 Physician United States
Primary
Concomitant
Paraesthesia Death 43 Male 180 lb 8/29/2006 United States
Primary
Concomitant
Jaw Disorder Other Serious Male 8/29/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Male 144 lb 12/29/2006 Physician United States
Primary
Concomitant
Wound Debridement Other Serious 5/1/2006 83 Female 164 lb 1/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 57 Male 144 lb 1/8/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2004 72 Male 1/17/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 10/23/2006 73 Female 100 lb 1/18/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2000 71 Male 1/25/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2004 73 Male 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/13/2005 45 Male 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/13/2005 45 Male 2/2/2007 Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/28/2002 Female 2/5/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/28/2002 Female 2/5/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/29/2007 51 Male 2/8/2007 Physician Japan
Primary
Concomitant
Tooth Malformation Other Serious 12/1/2005 59 Male 2/20/2007 United States
Primary
Concomitant
Pyrexia Hospitalization 1/29/2007 51 Male 2/14/2007 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 1/9/2006 71 Female 205 lb 2/16/2007 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 2/23/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Malformation Other Serious 12/1/2005 59 Male 2/20/2007 United States
Primary
Concomitant
Purulent Discharge Other Serious 4/1/2006 67 Male 3/8/2007 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Infarction Life Threatening 1/18/2007 61 Female 3/1/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 12/23/2006 62 Male 3/1/2007 Physician Russian Federation
Primary
Concomitant
Weight Decreased Other Serious 1/9/2006 71 Female 205 lb 3/7/2007 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 2/19/2007 70 Female 115 lb 3/15/2007 Physician Belgium
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 11/18/2006 82 Male 173 lb 3/9/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2000 71 Male 173 lb 3/17/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/15/2005 52 Male 3/16/2007 Physician United States
Primary
Concomitant
Myelocytosis Life Threatening 1/1/2007 74 Male 165 lb 3/23/2007 Consumer France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 2/19/2007 70 Female 115 lb 3/24/2007 Physician Belgium
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 3/8/2007 72 Male 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 2/1/2007 69 Male 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Discolouration Other Serious 1/1/2006 68 Male 182 lb 4/6/2007 United States
Primary
Concomitant
Multiple Myeloma Hospitalization 3/29/2007 Female 4/9/2007 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 2/19/2007 70 Female 115 lb 4/14/2007 Physician Belgium
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/31/2006 80 Female 79 lb 4/19/2007 Pharmacist Germany
Primary
Concomitant

Drug Data