Vancomycin combined with Voriconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 11/23/2004 1/6/2006 Physician United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/8/2005 17 Female 1/19/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tracheostomy Life Threatening 7/10/2005 42 Female 1/23/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombotic Stroke Death 10/27/2005 45 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/17/2005 Male 207 lb 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Administration Error Death 1/1/2004 2 Male 3/16/2006 Physician Poland
Primary
Concomitant
Sepsis Hospitalization 2/23/2006 67 Male 188 lb 3/3/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Enterococcal 56 Female 3/9/2006 United States
Primary
Secondary
Concomitant
Therapy Non-responder Death 2/1/2006 47 Female 123 lb 3/10/2006 Physician United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 66 Male 4/10/2006 Netherlands
Primary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 66 Male 4/21/2006 Physician Netherlands
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 3/10/2005 60 Male 176 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/8/2005 17 Female 5/12/2006 Other Health Professional France
Primary
Secondary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 5/25/2006 Physician Austria
Primary
Concomitant
Cardiomyopathy 22 Male 181 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Tremor Life Threatening 3/30/2006 65 Male 238 lb 5/18/2006 Physician United States
Primary
Concomitant
Hallucination Hospitalization 5/27/2006 54 Male 6/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Death 6/20/2006 Male 125 lb 6/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/12/2006 62 Male 7/27/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/12/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 6/12/2006 62 Male 9/1/2006 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 7/30/2006 59 Male 8/31/2006 United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 33 Female 9/1/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/8/2006 Other Health Professional Belgium
Primary
Concomitant
Respiratory Distress Death 7/20/2006 21 Female 132 lb 9/12/2006 Other Health Professional Belgium
Primary
Concomitant
Myocardial Infarction Death 7/20/2006 21 Female 132 lb 9/15/2006 Other Health Professional Belgium
Primary
Concomitant
Pyrexia Hospitalization 5/3/2006 56 Male 220 lb 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Required Intervention 1/1/2006 37 Female 9/28/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/30/2006 37 Female 10/13/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting 2/8/2006 36 Male Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Required Intervention 8/30/2006 37 Female 11/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 8/30/2006 37 Female 11/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Cellulitis Other Serious 11/17/2006 26 Female 12/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/15/2006 77 Male 12/21/2006 Other Health Professional France
Primary
Secondary
Pulmonary Mycosis Life Threatening 1/1/2005 Male 12/29/2006 Japan
Primary
Concomitant
Pulmonary Mycosis Life Threatening 10/5/2005 Male 3/23/2007 Japan
Primary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 3/27/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 3/27/2007 Male 163 lb 4/2/2007 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 2/7/2007 40 Male 4/5/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/27/2007 Male 163 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 11/1/2006 77 Male 4/27/2007 Other Health Professional France
Primary
Secondary
Virus Urine Test Positive Hospitalization 1/31/2007 40 Male 223 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Death 3/25/2007 Male 193 lb 5/10/2007 Physician United States
Primary
Secondary
Concomitant
Anaemia Haemolytic Autoimmune Other Serious 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 5/23/2007 61 Male 148 lb 7/6/2007 Physician Korea, Republic Of
Primary
Concomitant
Systemic Mycosis Life Threatening 4/1/2006 49 Female 99 lb 7/13/2007 Physician Austria
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Cerebellar Syndrome Death 5/21/2007 17 Male 7/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 7/27/2007 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/12/2007 Male 8/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Cerebellar Syndrome Death 5/21/2007 16 Male 8/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2006 39 Male 8/27/2007 Austria
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2007 Female 9/6/2007 Physician
Primary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Overdose Death Female 148 lb 9/11/2007 Other Health Professional United States
Primary
Concomitant
Oesophageal Stenosis Other Serious 3 Female 9/7/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 57 Male 9/13/2007 Consumer France
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 8/13/2007 10 Female 75 lb 9/11/2007 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 6/21/2007 Male 142 lb 9/21/2007 Other Health Professional United States
Primary
Concomitant
Varicose Vein Life Threatening 6/15/2007 67 Male 190 lb 10/1/2007 Physician United States
Primary
Concomitant
Sepsis Life Threatening 12/24/2006 Male 174 lb 10/17/2007 Consumer United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 2/9/2007 57 Female Physician United States
Primary
Concomitant
Pericarditis Fungal Other Serious 11/11/2005 3 Female 10/23/2007
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/24/2006 Male 174 lb 10/25/2007 Consumer United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 1/1/2007 57 Male 10/31/2007 Consumer France
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 9/25/2007 46 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/23/2007 Male 139 lb 11/7/2007 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 8/24/2004 Female 180 lb 11/16/2007 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/2/2007 15 Female 208 lb 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/23/2007 Male 139 lb 11/28/2007 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Life Threatening 11/5/2007 15 Female 208 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/20/2007 73 Male 191 lb 1/4/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 5/11/2007 9 Female 56 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Disability 1/18/2008 Male 2/8/2008 Physician Spain
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/10/2004 Female 234 lb 2/18/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 8/24/2004 Female 180 lb 2/25/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 10/24/2007 73 Male 191 lb 2/22/2008 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/13/2008 11 Female 44 lb 2/26/2008 Physician Ireland
Primary
Concomitant
Thrombocytopenia Life Threatening 11/29/2007 Female 90 lb 3/7/2008 Other Health Professional France
Primary
Concomitant
Interacting
Vomiting Hospitalization 1/13/2008 11 Female 44 lb 3/13/2008 Ireland
Primary
Concomitant
White Blood Cell Count Decreased 11/29/2007 Female 90 lb 3/31/2008 Other Health Professional France
Primary
Concomitant
Interacting
Cardiac Failure Death 3/8/2008 14 Female 4/25/2008 Physician Italy
Primary
Secondary
Concomitant
Vomiting 2/9/2007 57 Female 5/2/2008 Physician United States
Primary
Concomitant
Cardiac Failure Death 3/8/2008 14 Female 5/6/2008 Physician Italy
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Required Intervention 3/25/2008 41 Female 167 lb 3/25/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 61 Female 5/29/2008 Other Health Professional
Primary
Concomitant
White Blood Cell Count Increased Other Serious 61 Female 5/30/2008 Other Health Professional
Primary
Concomitant
Virus Urine Test Positive Hospitalization 17 Male 6/5/2008
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 61 Female 6/6/2008 Other Health Professional
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2008 61 Female 6/10/2008 Other Health Professional
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2008 61 Female 6/13/2008 Other Health Professional
Primary
Concomitant
Ventricular Fibrillation Required Intervention 4/13/2008 20 Male 139 lb 5/12/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2008 61 Female 6/18/2008 Other Health Professional
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 6/19/2008 Other Health Professional Japan
Primary
Secondary
Nephropathy Toxic Hospitalization 12/7/2007 58 Male 178 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/4/2007 69 Male 183 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nephropathy Toxic Hospitalization 12/5/2007 43 Male 197 lb 6/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2008 61 Female 6/26/2008 Other Health Professional
Primary
Concomitant
Respiratory Failure Death Male 193 lb 7/1/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 6/3/2008 61 Female 7/3/2008 Other Health Professional
Primary
Concomitant
Ventricular Hypokinesia Other Serious 6/3/2008 33 Male 134 lb 8/4/2008 United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 53 Female 8/18/2008 Other Health Professional Japan
Primary
Secondary
Gingival Hyperplasia Hospitalization 7/20/2008 Male 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 9/19/2008 Male 150 lb 11/5/2008 Spain
Primary
Concomitant
Ileus Hospitalization 8/21/2008 15 Female 86 lb 11/6/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/19/2008 Male 52 lb 11/5/2008 Other Health Professional Brazil
Primary
Concomitant
Potentiating Drug Interaction Other Serious 14 Male 141 lb 11/10/2008 Germany
Primary
Concomitant
Interacting
Respiratory Failure Life Threatening 6/24/2008 Female 163 lb 6/29/2008 Pharmacist United States
Primary
Concomitant
Gingival Hyperplasia 7/20/2008 Male 11/24/2008 Physician United States
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 7/25/2007 69 Male 11/28/2008 China
Primary
Concomitant
Drug Toxicity Death 8/24/2004 Female 180 lb 12/10/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 6/3/2008 33 Male 134 lb 12/5/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/3/2008 33 Male 134 lb 12/11/2008 United States
Primary
Secondary
Concomitant
Weight Increased Death 12/5/2008 69 Female 12/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 Female 93 lb 1/5/2009 Physician Thailand
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 12/9/2008 Male 96 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucinations, Mixed Other Serious 12/7/2008 1/21/2009 Physician Thailand
Primary
Secondary
Concomitant
Urticaria Hospitalization 15 Male 101 lb 1/23/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/9/2007 1/26/2009 Physician Singapore
Primary
Secondary
Concomitant
Tachypnoea Other Serious 1/21/2009 Female 154 lb 2/23/2009 Physician United States
Primary
Secondary
Respiratory Failure Other Serious 11/1/2007 3/11/2009 Other Health Professional Canada
Primary
Concomitant
Drug Resistance Other Serious 3/11/2009 Other Health Professional France
Primary
Concomitant
Sepsis Other Serious 64 Male 3/13/2009 Other Health Professional Austria
Primary
Concomitant
Pneumonia Death 10/24/2007 58 Female 112 lb 4/16/2009 Physician Belgium
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/9/2007 4/17/2009 Physician Egypt
Primary
Concomitant
Graft Versus Host Disease Death 7/5/2008 71 Male 157 lb 5/1/2009 Physician Belgium
Primary
Concomitant
Leukoencephalopathy Other Serious 2/13/2007 45 5/26/2009 Physician France
Primary
Concomitant
Shock Haemorrhagic Other Serious 3/23/2007 45 5/26/2009 Physician France
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 43 5/25/2009 Other Health Professional Canada
Primary
Concomitant
Death Death 10/29/2007 65 6/23/2009 Physician Korea, Republic Of
Primary
Concomitant
Sinusitis Aspergillus Other Serious 3 Female 7/2/2009
Primary
Secondary
Shock Life Threatening 1/21/2009 30 7/3/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Respiratory Failure Death 5/30/2008 54 7/7/2009 Physician Korea, Republic Of
Primary
Concomitant
Death Death 6/7/2006 70 7/8/2009 Physician Korea, Republic Of
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 54 7/21/2009 Physician Korea, Republic Of
Primary
Concomitant
Hallucination, Visual Other Serious 5/26/2009 Male 7/20/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 5/6/2009 69 8/4/2009 Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 5/6/2009 69 8/11/2009 Germany
Primary
Secondary
Concomitant
Renal Failure Acute Death 12/26/2008 61 8/11/2009 Physician Korea, Republic Of
Primary
Concomitant
Acute Respiratory Distress Syndrome Death 6/10/2009 68 8/11/2009 Physician Korea, Republic Of
Primary
Concomitant

Drug Data