Valproate Sodium combined with Zyprexa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thinking Abnormal Other Serious 10/1/2005 48 Male 163 lb 1/9/2006 Physician Portugal
Primary
Concomitant
Thinking Abnormal Other Serious 10/1/2005 48 Male 163 lb 1/31/2006 Physician Portugal
Primary
Concomitant
Pyrexia Hospitalization 7/7/2004 56 Male 89 lb 1/31/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Oedema Hospitalization 53 Female 3/20/2006 Other Health Professional Australia
Primary
Concomitant
Weight Increased Hospitalization 12/15/2005 50 Male 4/5/2006 Physician France
Primary
Concomitant
Transaminases Increased 4/7/2006 Male 4/24/2006 Physician Germany
Primary
Concomitant
Neutropenia 35 Male 4/28/2006 Physician France
Primary
Concomitant
Tremor Other Serious 1/1/2006 50 Male 5/15/2006 Physician Finland
Primary
Concomitant
Weight Increased Hospitalization 1/1/1999 55 Female 148 lb 6/8/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/13/2006 24 Female 7/3/2006 Pharmacist Japan
Primary
Concomitant
Weight Increased Hospitalization 1/1/1999 55 Female 148 lb 7/11/2006 Lawyer United States
Primary
Concomitant
Stereotypy Disability 5/12/2006 62 Male 7/26/2006 Physician Germany
Primary
Secondary
Concomitant
Neutropenia 1/1/2005 30 Male 7/23/2006 Physician France
Primary
Concomitant
Pulmonary Fibrosis Other Serious 5/1/2006 71 Female 7/26/2006 Physician Germany
Primary
Concomitant
Hypomania Death 1/1/2003 51 Male 8/8/2006 Finland
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 32 Female 200 lb 8/28/2006 Lawyer United States
Primary
Concomitant
Completed Suicide Death 1/1/2003 51 Male 8/31/2006 Finland
Primary
Concomitant
Weight Increased Hospitalization 5/11/2006 65 Female 176 lb 9/3/2006 France
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2006 47 Male 9/13/2006 Physician Brazil
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 47 Male 9/18/2006 Brazil
Primary
Concomitant
Weight Increased Hospitalization 5/11/2006 65 Female 176 lb 9/11/2006 France
Primary
Concomitant
White Blood Cell Count Increased 1/1/2003 53 Male 9/21/2006 Pharmacist United Kingdom
Primary
Concomitant
White Blood Cell Count Increased 53 Male 10/30/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 53 Female 10/8/2006 Physician France
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/25/2005 32 Male 176 lb 11/9/2006 Physician Germany
Primary
Concomitant
Tachyarrhythmia Hospitalization 10/25/2005 32 Male 176 lb 11/15/2006 Physician Germany
Primary
Concomitant
Hyponatraemia Other Serious 1/7/2005 63 Female 165 lb 12/5/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12 Female 1/2/2007 Physician Japan
Primary
Concomitant
Completed Suicide Death 12/23/2006 36 Female 137 lb 1/20/2007 Physician Mexico
Primary
Secondary
Concomitant
Prescribed Overdose Hospitalization 1/1/1998 41 Female 130 lb 10/10/2006 Consumer United States
Primary
Concomitant
Completed Suicide Death 12/23/2006 36 Female 137 lb 1/26/2007 Physician Mexico
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/7/2005 63 Female 165 lb 1/30/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 12/4/2006 21 Male 2/5/2007 Physician United Kingdom
Primary
Concomitant
Interacting
Neuroleptic Malignant Syndrome Other Serious 12/4/2006 21 Male 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urinary Incontinence Other Serious 1/1/2007 60 Male 154 lb 2/21/2007 Consumer Netherlands
Primary
Secondary
Concomitant
Speech Disorder Other Serious 7/25/2006 50 Female 3/21/2007 Physician Germany
Primary
Concomitant
Sedation Other Serious 1/1/2006 63 Male 3/22/2007 Physician Germany
Primary
Concomitant
Sedation Other Serious 1/1/2006 63 Male 3/29/2007 Physician Germany
Primary
Concomitant
Prescribed Overdose Life Threatening 3/22/2007 29 Male 4/30/2007 Physician Norway
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 1/1/2007 36 Female 5/16/2007 Consumer Australia
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2007 36 Female 5/17/2007 Consumer Australia
Primary
Concomitant
Infarction Death 64 Male 218 lb 6/8/2007 Physician Mexico
Primary
Concomitant
Weight Decreased Hospitalization 1/1/1999 31 Female 156 lb 4/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 30 Male 185 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 41 Female 170 lb 4/2/2007 Consumer United States
Primary
Concomitant
Infarction Death 5/17/2007 64 Male 218 lb 7/16/2007 Physician Mexico
Primary
Concomitant
Myocardial Infarction Death 5/17/2007 64 Male 218 lb 8/16/2007 Physician Mexico
Primary
Concomitant
Weight Increased Other Serious 11/1/2007 35 Male 1/29/2008 Physician Australia
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/1/2008 Female 3/5/2008 Physician Norway
Primary
Concomitant
Interacting
Rash Generalised Other Serious 20 Male 3/9/2008 Consumer
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 2/1/2008 Female 3/25/2008 Physician Australia
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 20 Male 4/9/2008 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/31/2008 57 Male 4/24/2008 Other Health Professional Ireland
Primary
Concomitant
Overdose Hospitalization 4/1/2008 36 Female 4/30/2008 Physician South Africa
Primary
Concomitant
Unevaluable Event Other Serious Male 6/6/2008 Lawyer Norway
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/1/2005 22 Male 6/6/2008 Physician United Kingdom
Primary
Concomitant
Hospitalisation Hospitalization 12/26/2007 37 Male 6/20/2008 Physician Germany
Primary
Concomitant
Gastric Haemorrhage Death 2/1/2008 42 Male 7/12/2008 Physician United Kingdom
Primary
Concomitant
Hospitalisation Hospitalization 1/1/2008 Female 165 lb 7/8/2008 Physician Romania
Primary
Concomitant
Serotonin Syndrome Other Serious 44 Male 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia 25 Male 7/28/2008 Physician New Zealand
Primary
Concomitant
Tearfulness Hospitalization 12/26/2007 37 Male 7/31/2008 Physician Germany
Primary
Concomitant
Sedation Hospitalization 7/27/2008 65 Male 8/6/2008 Physician Germany
Primary
Concomitant
Pulmonary Embolism Other Serious 25 Male 8/25/2008 Physician Belgium
Primary
Concomitant
Overdose Death 6/12/2008 Female 8/27/2008 Physician United States
Primary
Concomitant
Diabetic Coma Other Serious 1/1/2005 28 Male 180 lb 9/16/2008 United States
Primary
Concomitant
Sedation Hospitalization 7/27/2008 Male 9/18/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased 17 Female 10/9/2008 Physician Japan
Primary
Concomitant
Tremor Required Intervention 3/20/2008 Male 170 lb 10/13/2008 Consumer United States
Primary
Secondary
Overdose Death 6/12/2008 Female 11/3/2008 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/2/2008 Female 10/23/2008 Physician Norway
Primary
Concomitant
Irritability Other Serious 12/19/2008 Other Health Professional Sweden
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 5/2/2008 55 Female 12/29/2008 Physician Germany
Primary
Secondary
Neutrophil Count Decreased Other Serious 10/14/2008 53 Male 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Rash Papular Other Serious 7/16/2008 Male 141 lb 3/9/2009 Physician Belgium
Primary
Secondary
Concomitant
Drug Toxicity Death 42 Male 3/26/2009 United States
Primary
Secondary
Restless Legs Syndrome Other Serious 59 Male 3/31/2009 Physician Korea, Republic Of
Primary
Concomitant
Drug Toxicity Death 42 Male 4/6/2009 Denmark
Primary
Secondary
Pulmonary Embolism Death 1/6/2009 34 Male 4/10/2009 Physician Ireland
Primary
Secondary
Speech Disorder Other Serious 37 Male 4/29/2009 Physician Ireland
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 23 Male 150 lb 5/21/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/2/2008 43 Male 218 lb 5/22/2009 Pharmacist United States
Primary
Concomitant
Pancytopenia Other Serious 1/1/2007 Female 6/5/2009 Physician United Kingdom
Primary
Concomitant
Overdose Death 1/1/2007 Male 5/28/2009 Physician United States
Primary
Concomitant
Rectal Fissure Hospitalization 3/19/2009 Female 6/16/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 10/14/2008 53 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 1/1/2009 Male 7/31/2009 Consumer United Kingdom
Primary
Concomitant
Overdose Death 40 Male 9/10/2009 Physician United Kingdom
Primary
Concomitant
Rabbit Syndrome Hospitalization 8/1/2009 45 Female 9/29/2009 Physician New Zealand
Primary
Concomitant
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 10/30/2009 Physician China
Primary
Concomitant
Nasopharyngitis Other Serious 55 Male 205 lb 11/11/2009 Physician United Kingdom
Primary
Concomitant
Serotonin Syndrome Hospitalization 61 Male 11/10/2009 Norway
Primary
Secondary
Concomitant
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 11/30/2009 Physician China
Primary
Concomitant
Treatment Noncompliance Other Serious 25 Male 12/1/2009 Physician Belgium
Primary
Concomitant
Pancytopenia Other Serious 1/1/2007 Female 12/1/2009 Physician United Kingdom
Primary
Concomitant
Overdose Other Serious 4/1/2007 Male 12/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Heart Rate Decreased Other Serious 10/16/2009 20 Female 101 lb 1/4/2010 Physician China
Primary
Concomitant
Rhabdomyolysis Other Serious 76 Female 1/11/2010 Physician United Kingdom
Primary
Concomitant
Tremor Other Serious 1/1/2008 Male 185 lb 1/19/2010 Physician Germany
Primary
Concomitant
Thirst Other Serious 12/31/2009 29 Male 2/22/2010 Physician Australia
Primary
Secondary
Concomitant
Somnolence Other Serious 76 Male 3/8/2010 Physician Japan
Primary
Concomitant
Thirst Other Serious 12/31/2009 29 Male 2/25/2010 Physician Australia
Primary
Secondary
Concomitant
Gastrointestinal Necrosis Other Serious Male 3/12/2010 Physician United Kingdom
Primary
Concomitant
Pruritus Other Serious 10/21/2009 44 Female 4/8/2010 France
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 4/1/2010 30 Male 5/3/2010 Physician Peru
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 4/21/2010 52 Female 4/30/2010 Physician South Africa
Primary
Concomitant
Rash Maculo-papular Other Serious 12/30/2008 24 Female 5/28/2010 Physician Malaysia
Primary
Concomitant
Hyperglycaemia Hospitalization 2/1/2010 57 Male 6/4/2010 Physician Australia
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 4/1/2010 30 Male 6/14/2010 Physician Peru
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 3/3/2010 21 Male 8/6/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neutropenia 7/1/2010 43 Female 8/16/2010 Physician Norway
Primary
Concomitant
Swelling Face Other Serious 8/8/2010 16 Female 9/1/2010 Physician Finland
Primary
Concomitant
Obesity Other Serious 11/1/2009 Female 9/7/2010 Physician United Kingdom
Primary
Concomitant
Epistaxis 30 Female 9/8/2010 Physician Australia
Primary
Concomitant
Overdose Other Serious 53 Female 9/13/2010 Physician New Zealand
Primary
Concomitant
Drug Toxicity Other Serious 3/3/2010 21 Male 10/8/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/1/2000 34 Female 12/15/2010 Physician Canada
Primary
Secondary
Concomitant
Blindness Other Serious Female 1/31/2011 Physician Canada
Primary
Concomitant
Drug Interaction Other Serious 9/26/2006 30 Male 2/24/2011 Physician Korea, Republic Of
Primary
Concomitant
Neutropenia Other Serious 11/1/2008 31 Female 2/24/2011 Physician Korea, Republic Of
Primary
Concomitant
Pleural Effusion Other Serious 22 Female 3/3/2011 Physician China
Primary
Concomitant
Hallucination Other Serious 9/1/2010 53 Male 4/15/2011 Physician Japan
Primary
Concomitant
Drug Exposure During Pregnancy Life Threatening 24 4/12/2011 Consumer United Kingdom
Primary
Concomitant
Oedema Peripheral Other Serious 8/12/2010 53 Male 5/3/2011 Physician Japan
Primary
Concomitant
Erectile Dysfunction Death 3/6/2008 50 Male 5/18/2011 Physician Canada
Primary
Concomitant
Overdose Hospitalization 5/1/2011 26 Female 5/19/2011 Physician South Africa
Primary
Concomitant
Hypercholesterolaemia Other Serious Male 228 lb 5/23/2011 Physician Canada
Primary
Concomitant
Haematuria Hospitalization Male 6/6/2011 Physician Canada
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious Male 6/7/2011 Physician Canada
Primary
Concomitant
Aggression Death 3/25/2007 46 Male 6/1/2011 Physician Canada
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization Male 231 lb 6/9/2011 Physician Canada
Primary
Secondary
Concomitant
Renal Artery Occlusion Hospitalization 12/28/1999 34 Male 6/13/2011 Physician Canada
Primary
Concomitant
Cardiac Arrest Other Serious 11/20/2004 28 Male 6/13/2011 Physician Canada
Primary
Secondary
Concomitant
Dizziness Hospitalization Female 6/14/2011 Physician France
Primary
Concomitant
Erythroid Series Abnormal Other Serious Male 6/17/2011 Physician Canada
Primary
Concomitant
Weight Increased Other Serious Male 6/23/2011 Consumer Canada
Primary
Secondary
Concomitant
Hypertension Other Serious 5/5/2006 41 Male 6/21/2011 Consumer Canada
Primary
Secondary
Concomitant
Myoclonus Other Serious 50 Male 7/4/2011 Physician Japan
Primary
Concomitant
Hepatic Steatosis Other Serious 2/1/2009 56 Male 6/30/2011 Physician Canada
Primary
Secondary
Concomitant
Lethargy Other Serious Male 6/30/2011 Consumer Canada
Primary
Concomitant
Weight Increased Hospitalization 12/17/1999 26 Male 7/6/2011 Consumer Canada
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious Male 7/12/2011 Consumer Canada
Primary
Concomitant
Overdose 1/1/2007 50 Female 7/13/2011 Physician Canada
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 65 Female 7/15/2011 Physician Japan
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 7/18/2011 Consumer Canada
Primary
Secondary
Concomitant
Haematocrit Decreased Other Serious 1/15/2002 47 Male 7/18/2011 Consumer Canada
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 3/7/2011 59 Male 7/27/2011 Other Health Professional Sweden
Primary
Concomitant
Hepatitis Acute Hospitalization 2/25/2011 45 Male 231 lb 7/26/2011 Physician Germany
Primary
Concomitant
Accidental Exposure Hospitalization 5 37 lb 7/27/2011 Physician Japan
Primary
Concomitant

Drug Data