Tykerb combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Platelet Disorder Other Serious Female 4/30/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 46 Female 5/2/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 4/1/2007 46 Female 5/9/2007 Consumer United States
Primary
Concomitant
Rash Hospitalization 3/1/2007 66 Female 167 lb 6/6/2007 Consumer United States
Primary
Secondary
Concomitant
Rash 4/1/2007 59 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 4/15/2007 67 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 4/21/2007 65 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 4/1/2007 43 Female 7/6/2007 Consumer United States
Primary
Concomitant
Rash 4/29/2007 71 Female 7/6/2007 Consumer United States
Primary
Concomitant
Pruritus 52 Female 7/6/2007 Consumer United States
Primary
Concomitant
Nausea 4/1/2007 39 Female 7/6/2007 Consumer United States
Primary
Concomitant
Fatigue 4/1/2007 43 Female 7/6/2007 Consumer United States
Primary
Concomitant
Fatigue 4/27/2007 44 Female 7/6/2007 Consumer United States
Primary
Concomitant
Oral Pain 5/13/2007 44 Female 7/6/2007 Consumer United States
Primary
Concomitant
Rash 4/1/2007 55 Female 7/6/2007 Consumer United States
Primary
Concomitant
Dysphagia 5/15/2007 61 Female 7/6/2007 Consumer United States
Primary
Concomitant
Vomiting 57 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 49 Female 138 lb 7/6/2007 Other Health Professional United States
Primary
Concomitant
Diarrhoea 5/1/2007 59 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 5/9/2007 51 Female 7/6/2007 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 5/14/2007 70 Female 7/6/2007 Consumer United States
Primary
Concomitant
Blister Other Serious 7/28/2007 45 Female 8/7/2007 Consumer United States
Primary
Concomitant
Oral Herpes 1/1/2007 59 Female 122 lb 10/11/2007 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper 5/14/2007 70 Female 10/11/2007 Consumer United States
Primary
Concomitant
Skin Ulcer 6/1/2007 52 Female 120 lb 10/11/2007 Consumer United States
Primary
Concomitant
Diarrhoea 7/8/2007 51 Female 10/11/2007 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome 7/1/2007 Female 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased 1/1/2007 48 Female 10/11/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2007 65 Female 10/11/2007 Consumer United States
Primary
Concomitant
Pruritus Generalised 55 Female 10/11/2007 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 8/1/2007 40 Female 231 lb 11/27/2007 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection 9/28/2007 54 Female 1/11/2008 Other Health Professional United States
Primary
Concomitant
Surgery 9/27/2007 46 Female 141 lb 1/11/2008 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/11/2008 49 Female 266 lb 5/10/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia 5/2/2008 Female 7/3/2008 Consumer United States
Primary
Concomitant
Death Death 5/23/2008 Female 152 lb 7/10/2008 Consumer United States
Primary
Concomitant
Disease Progression Death Female 136 lb 7/29/2008 Physician United States
Primary
Concomitant
Tachypnoea Hospitalization 5/1/2008 56 Female 7/31/2008 Physician United States
Primary
Concomitant
Ischaemic Stroke Other Serious 8/22/2008 Female 145 lb 10/14/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 11/12/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 9/10/2008 46 Female 1/6/2009 Consumer United States
Primary
Concomitant
Skin Chapped 9/22/2008 57 Female 1/6/2009 Consumer United States
Primary
Concomitant
Skin Disorder 9/24/2008 45 Female 1/6/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2008 46 Female 2/23/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/1/2008 66 Female 3/18/2009 Consumer United States
Primary
Concomitant
Rash 12/28/2008 61 Female 175 lb 4/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia 1/4/2009 61 Female 4/2/2009 Consumer United States
Primary
Concomitant
Diarrhoea 2/23/2009 49 Female 4/2/2009 Consumer United States
Primary
Concomitant
Wound 47 Female 4/2/2009 Consumer United States
Primary
Concomitant
Pyrexia 1/25/2009 61 Female 7/10/2009 Consumer United States
Primary
Concomitant
Onychoclasis 2/18/2009 69 Female 147 lb 7/10/2009 Consumer United States
Primary
Concomitant
Fatigue 3/17/2009 59 Female 7/10/2009 Consumer United States
Primary
Concomitant
Skin Disorder 57 Female 7/10/2009 Consumer United States
Primary
Concomitant
Nausea 4/20/2009 59 Female 7/10/2009 Consumer United States
Primary
Concomitant
Mouth Ulceration 4/15/2009 71 Female 7/10/2009 Consumer United States
Primary
Concomitant
Vomiting 5/2/2009 44 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased 3/1/2009 50 Female 7/10/2009 Other Health Professional United States
Primary
Concomitant
Nausea 5/24/2009 70 Female 7/10/2009 Consumer United States
Primary
Concomitant
Pain Other Serious 46 Female 7/30/2009 Physician Brazil
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 6/1/2009 68 Female 8/18/2009 Physician Brazil
Primary
Secondary
Pain Other Serious 46 Female 9/9/2009 Physician Brazil
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 7/31/2009 Female 322 lb 9/10/2009 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 7/30/2009 Female 322 lb 9/21/2009 Physician Japan
Primary
Concomitant
Throat Tightness 5/29/2009 43 Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Dry Skin 59 Female 9/24/2009 Consumer United States
Primary
Concomitant
Weight Decreased Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Nausea 9/6/2009 66 Female 9/24/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 6/1/2009 65 Female 10/21/2009 Physician Brazil
Primary
Secondary
Concomitant
Yellow Skin Other Serious 49 Female 89 lb 10/28/2009 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/30/2009 Female 322 lb 11/4/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 6/1/2009 65 Female 11/9/2009 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 6/14/2009 51 Female 202 lb 12/23/2009 Consumer United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 3/1/2009 44 Female 150 lb 1/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 3/1/2009 44 Female 150 lb 1/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 10/13/2009 53 Female 1/8/2010 Consumer United States
Primary
Concomitant
Nausea Female 1/8/2010 Consumer United States
Primary
Concomitant
Sleep Disorder 1/1/2009 Female 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Tongue Discolouration Other Serious 3/1/2009 Female 150 lb 1/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tongue Discolouration Other Serious 3/1/2009 Female 150 lb 2/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Monoplegia Other Serious 9/1/2008 36 Female 2/4/2010 Physician Japan
Primary
Secondary
Concomitant
Monoplegia Hospitalization 9/1/2008 36 Female 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/1/2009 Female 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
Infusion Site Necrosis Other Serious 60 Female 152 lb 2/12/2010 Pharmacist United States
Primary
Concomitant
Swelling Hospitalization 10/3/2009 Female 152 lb 2/24/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/25/2005 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/1/2009 Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/1/2002 Female 146 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/1/2009 Female 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 Female 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 10/1/2009 Female 152 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/29/2007 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 7/23/2004 Female 119 lb 3/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 Female 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Rash Pustular 33 Female 4/9/2010 Consumer United States
Primary
Concomitant
Vomiting 40 Female 4/9/2010 Consumer United States
Primary
Concomitant
Weight Decreased 40 Female 4/9/2010 Consumer United States
Primary
Secondary
Vision Blurred Other Serious 11/29/2007 55 Female 4/11/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 4/14/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 7/23/2004 49 Female 119 lb 4/15/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 4/22/2010 United States
Primary
Concomitant
Swelling Hospitalization 10/1/2009 62 Female 152 lb 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/9/2009 35 Female 106 lb 4/28/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 1/27/2010 35 Female 95 lb 4/29/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/23/2004 49 Female 119 lb 5/6/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 5/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Disability 1/27/2010 35 Female 95 lb 5/17/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/9/2009 35 Female 106 lb 5/18/2010 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Disability 3/17/2010 60 Female 5/18/2010 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Disability 3/17/2010 60 Female 5/21/2010 Physician Japan
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 5/28/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 58 Female 100 lb 6/7/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 6/7/2010 United States
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/9/2010 United States
Primary
Concomitant
Polyneuropathy Disability 3/18/2010 60 Female 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Polyneuropathy Disability 3/18/2010 60 Female 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/15/2010 United States
Primary
Concomitant
Blood Bilirubin Increased Other Serious Female 97 lb 7/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 7/8/2010 United States
Primary
Concomitant
Vomiting Hospitalization 2/23/2010 69 Female 88 lb 7/13/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 7/22/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/23/2010 United States
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 9/22/2009 67 Female 75 lb 8/10/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/25/2009 74 Female 121 lb 8/11/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting 2/23/2010 69 Female 88 lb 8/12/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Other Serious 9/22/2009 67 Female 75 lb 8/24/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 8/27/2010 United States
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 8/27/2010 United States
Primary
Concomitant
Oophorectomy Other Serious Female 8/30/2010 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 11/25/2009 74 Female 121 lb 9/1/2010 Physician Japan
Primary
Secondary
Concomitant
Eczema Other Serious 7/10/2010 42 Female 121 lb 9/1/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/1/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 9/8/2010 United States
Primary
Concomitant
Anaemia Other Serious 3/17/2010 54 Female 126 lb 9/13/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal 3/1/2010 52 Female 97 lb 9/15/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Polyneuropathy Disability 3/18/2010 60 Female 106 lb 9/15/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/16/2010 United States
Primary
Secondary
Concomitant
Onychomadesis Other Serious 70 Female 9/21/2010 Consumer United States
Primary
Secondary
Concomitant
Eczema Other Serious 7/10/2010 42 Female 121 lb 9/22/2010 Physician Japan
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 116 lb 9/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 145 lb 9/28/2010 United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 66 Female 9/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1995 47 Male 10/5/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 8/1/2010 46 Female 124 lb 10/7/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 11/16/2007 55 Female 276 lb 10/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/31/2009 72 Female 84 lb 10/18/2010 Physician Japan
Primary
Concomitant

Drug Data