Tykerb combined with Vitamin D

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tongue Ulceration 4/23/2007 63 Female 7/6/2007 Consumer United States
Primary
Concomitant
Transaminases Increased Other Serious 7/17/2007 43 Female 167 lb 8/21/2007 Pharmacist United States
Primary
Concomitant
Skin Ulcer 6/1/2007 52 Female 120 lb 10/11/2007 Consumer United States
Primary
Concomitant
Diarrhoea 7/8/2007 51 Female 10/11/2007 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 6/28/2007 76 Female 152 lb 10/11/2007 Consumer United States
Primary
Secondary
Concomitant
Skin Reaction 62 Female 1/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/27/2007 54 Female 143 lb 2/7/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/27/2007 54 Female 143 lb 3/24/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 9/26/2008 Female 183 lb 9/26/2008 Physician United States
Primary
Secondary
Concomitant
Flatulence 9/10/2008 64 Female 10/10/2008 Consumer United States
Primary
Concomitant
No Therapeutic Response Hospitalization 9/26/2008 Female 183 lb 10/9/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 11/12/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2007 52 Female 120 lb 12/2/2008 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 70 Female 2/19/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2008 46 Female 2/23/2009 Consumer United States
Primary
Secondary
Concomitant
Tongue Disorder 2/1/2009 71 Female 4/2/2009 Consumer United States
Primary
Secondary
Concomitant
Thirst 3/1/2009 43 Female 4/2/2009 Consumer United States
Primary
Concomitant
Rash 3/21/2009 64 Female 7/10/2009 Consumer United States
Primary
Concomitant
Vomiting 4/1/2009 60 Female 7/10/2009 Consumer United States
Primary
Concomitant
Nausea 3/31/2009 66 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Urticaria 4/19/2009 43 Female 7/10/2009 Consumer United States
Primary
Concomitant
Pruritus 6/1/2009 76 Female 9/24/2009 Consumer United States
Primary
Concomitant
Hypotension 8/5/2009 51 Female 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Dizziness 8/29/2009 46 Female 1/8/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 11/25/2009 41 Female 1/8/2010 Consumer United States
Primary
Concomitant
Disease Progression Other Serious 1/19/2010 68 Female 1/27/2010 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 1/1/2009 68 Female 106 lb 2/18/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 6/25/2005 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 Female 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 Female 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting 39 Female 4/9/2010 Consumer United States
Primary
Concomitant
Tongue Disorder 68 Female 4/9/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 5/11/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 5/13/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 5/14/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 5/19/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/23/2010 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization Female 9/29/2010 Consumer Canada
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 10/15/2010 United States
Primary
Secondary
Concomitant
Skin Chapped Other Serious Female 10/27/2010 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization Female 10/28/2010 Consumer Canada
Primary
Concomitant
Vomiting Life Threatening Female 11/3/2010 Physician Canada
Primary
Secondary
Concomitant
Skin Chapped Other Serious Female 11/8/2010 Physician Canada
Primary
Concomitant
Stomatitis Hospitalization Female 12/14/2010 Consumer Canada
Primary
Secondary
Concomitant
Asthenia Hospitalization Female 1/20/2011 Consumer Canada
Primary
Secondary
Concomitant
Alopecia Hospitalization 96 Female 3/1/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious Female 3/8/2011 Consumer Canada
Primary
Concomitant
Nausea Other Serious Female 3/23/2011 Consumer Canada
Primary
Secondary
Concomitant
Liver Disorder Death 68 Female 145 lb 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 62 Female 4/4/2011 Consumer United States
Primary
Concomitant
Liver Disorder Death Female 145 lb 4/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 12/1/2010 52 Female 5/2/2011 Consumer United States
Primary
Concomitant
Diarrhoea 4/8/2010 49 Female 5/2/2011 Consumer United States
Primary
Concomitant
Treatment Failure 6/26/2010 68 Female 145 lb 5/2/2011 Consumer United States
Primary
Secondary
Concomitant
Nerve Injury 63 Female 5/2/2011 Consumer United States
Primary
Concomitant
Diarrhoea 1/8/2011 75 Female 5/2/2011 Consumer United States
Primary
Concomitant
Oral Pain 12/10/2010 59 Female 122 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Skin Exfoliation 62 Female 165 lb 5/2/2011 Consumer United States
Primary
Concomitant
Thermal Burn 2/8/2011 42 Female 5/2/2011 Consumer United States
Primary
Concomitant
Diarrhoea 3/4/2011 75 Female 5/2/2011 Consumer United States
Primary
Concomitant
Inappropriate Affect Hospitalization 50 Female 5/18/2011 Consumer United States
Primary
Secondary
Concomitant
Dysphonia Other Serious 5/6/2011 61 Female 5/24/2011 Consumer United States
Primary
Concomitant
Haematochezia Other Serious 5/6/2011 61 Female 6/1/2011 Consumer United States
Primary
Concomitant
Cough Other Serious 5/6/2011 61 Female 6/21/2011 Consumer United States
Primary
Concomitant
Oral Mucosal Exfoliation Other Serious 3/1/2011 60 Female 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious 7/1/2010 62 Female 126 lb 7/13/2011 Physician United States
Primary
Secondary
Concomitant
Stress Other Serious 5/6/2011 61 Female 7/18/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal Hospitalization 6/1/2011 55 Female 7/26/2011 Consumer United States
Primary
Concomitant
Corrective Lens User Other Serious 5/6/2011 61 Female 7/28/2011 Consumer United States
Primary
Concomitant
Erythema Other Serious 1/12/2011 49 Female 8/11/2011 Consumer Canada
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 1/13/2010 66 Female 8/18/2011 Consumer Canada
Primary
Secondary
Concomitant
Cough Other Serious 6/1/2011 69 Female 8/18/2011 Physician Canada
Primary
Concomitant
Dehydration Life Threatening 10/10/2010 59 Female 9/12/2011 Consumer Canada
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Female 10/4/2011 Consumer Canada
Primary
Concomitant
Splenomegaly Hospitalization 6/25/2005 55 Female 10/13/2011 United States
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious Female 11/2/2011 Consumer Canada
Primary
Concomitant
Death Death 58 Female 11/9/2011 Consumer United States
Primary
Concomitant
Ecchymosis Other Serious 10/19/2011 63 Female 193 lb 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/4/2011 53 Male 12/5/2011 Consumer United States
Primary
Concomitant
Death Death Female 12/12/2011 Canada
Primary
Concomitant
Death Death 12/8/2011 57 Female 12/14/2011 Consumer United States
Primary
Concomitant
Memory Impairment Hospitalization 5/6/2011 61 Female 12/16/2011 Consumer United States
Primary
Concomitant
Death Death 12/10/2011 64 Female 138 lb 12/28/2011 Consumer United States
Primary
Concomitant
Nausea Other Serious 12/1/2011 89 Female 1/18/2012 Consumer United States
Primary
Concomitant
Rash Macular Other Serious 1/20/2011 68 Female 2/28/2012 Consumer Canada
Primary
Secondary
Concomitant
Breast Cancer Metastatic Other Serious Female 2/29/2012 Consumer Canada
Primary
Secondary
Concomitant
Death Death 53 Female 3/5/2012 Consumer United States
Primary
Concomitant
Death Death 1/1/2011 55 Male 4/5/2012 Consumer United States
Primary
Concomitant
Death Death 1/1/2011 55 Female 4/9/2012 Consumer United States
Primary
Concomitant
Nausea Other Serious 12/1/2011 89 Female 4/18/2012 Consumer United States
Primary
Concomitant
Diarrhoea 1/8/2011 75 Female 168 lb 5/11/2012 Consumer United States
Primary
Concomitant
Diarrhoea 4/1/2011 44 Female 145 lb 5/11/2012 Consumer United States
Primary
Concomitant
Diarrhoea 5/1/2011 53 Female 211 lb 5/11/2012 Consumer United States
Primary
Concomitant
Dysgeusia 5/1/2011 68 Female 164 lb 5/11/2012 Consumer United States
Primary
Concomitant
Rash 3/1/2011 74 Female 5/11/2012 Consumer United States
Primary
Concomitant
Gait Disturbance 8/4/2011 67 Female 5/11/2012 Consumer United States
Primary
Concomitant
Rash Erythematous 10/15/2011 41 Female 175 lb 5/11/2012 Consumer United States
Primary
Concomitant
Diarrhoea Female 5/11/2012 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 7/9/2011 57 Female 102 lb 5/11/2012 Consumer United States
Primary
Concomitant
Deformity 11/15/2011 60 Female 150 lb 5/11/2012 Consumer United States
Primary
Concomitant
Erythema Female 5/11/2012 Consumer United States
Primary
Secondary
Concomitant
Alopecia 12/1/2011 38 Female 5/11/2012 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 5/1/2012 45 Female 5/15/2012 Consumer Canada
Primary
Concomitant
Liver Disorder Death 5/1/2012 45 Female 6/13/2012 Consumer Canada
Primary
Concomitant
Deafness Hospitalization 5/6/2011 61 Female 6/21/2012 Other Health Professional United States
Primary
Concomitant
Ophthalmoplegia Other Serious Female 6/27/2012 Consumer Canada
Primary
Concomitant
Weight Increased Other Serious 63 Female 7/30/2012 Consumer Canada
Primary
Secondary
Concomitant
Renal Failure Hospitalization 62 Female 8/20/2012 Consumer Canada
Primary
Secondary
Concomitant
Nausea Other Serious 60 Female 8/20/2012 Physician Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/2/2011 56 Female 12/28/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious Female 12/12/2012 Consumer Ca
Primary
Concomitant
Vomiting Hospitalization 11/16/2010 66 Female 119 lb 9/27/2012 Physician Ca
Primary
Secondary
Concomitant
Death Death 9/2012 54 Female 9/28/2012 Consumer Us
Primary
Concomitant
Dyspepsia Hospitalization 9/2012 Female 10/12/2012 Consumer Ca
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 1/28/2012 49 Female 123 lb 1/4/2013 Consumer Ca
Primary
Secondary
Concomitant
Rash Macular Hospitalization 11/10/2011 59 Female 12/13/2012 Consumer Ca
Primary
Concomitant
Tremor Death 5/3/2012 82 Female 2/20/2013 Consumer Us
Primary
Concomitant
Hospice Care Death 6/3/2012 57 Female 140 lb 3/4/2013 Consumer Us
Primary
Concomitant
Weight Decreased Hospitalization 9/2012 54 Female 154 lb 10/29/2012 Consumer Us
Primary
Secondary
Concomitant
Muscle Spasms 6/2009 80 Female 5/10/2013 Consumer Us
Primary
Concomitant
Oropharyngeal Pain 3/21/2012 61 Female 146 lb 5/10/2013 Consumer Us
Primary
Concomitant
Diarrhoea 4/2/2012 68 Female 5/10/2013 Consumer Us
Primary
Concomitant
Rash 3/21/2012 52 Female 5/10/2013 Consumer Us
Primary
Concomitant
Rash 4/17/2008 53 Female 218 lb 5/10/2013 Consumer Us
Primary
Concomitant
Malaise 45 Female 195 lb 5/10/2013 Consumer Us
Primary
Concomitant
Vomiting 5/24/2012 59 Female 131 lb 5/10/2013 Consumer Us
Primary
Concomitant
Nausea 6/27/2012 77 Female 5/10/2013 Consumer Us
Primary
Concomitant
Epistaxis 6/28/2012 66 Female 5/10/2013 Consumer Us
Primary
Concomitant
Weight Decreased 5/28/2012 27 Female 140 lb 5/10/2013 Consumer Us
Primary
Concomitant
Fatigue 7/21/2012 58 Female 124 lb 5/10/2013 Consumer Us
Primary
Concomitant
Rash 7/1/2012 54 Female 5/10/2013 Consumer Us
Primary
Concomitant
Lip Swelling Female 5/10/2013 Consumer Us
Primary
Concomitant
Diarrhoea 6/4/2012 52 Female 261 lb 5/10/2013 Consumer Us
Primary
Concomitant
Local Swelling 8/18/2012 55 Female 5/10/2013 Consumer Us
Primary
Concomitant
Pyrexia 52 Female 165 lb 5/10/2013 Consumer Us
Primary
Concomitant
Vomiting 10/1/2012 50 Female 162 lb 5/10/2013 Consumer Us
Primary
Concomitant
Vision Blurred 60 Female 5/10/2013 Consumer Us
Primary
Concomitant
Swelling 5/11/2012 57 Female 128 lb 5/10/2013 Consumer Us
Primary
Concomitant
Dry Skin 12/1/2010 61 Female 138 lb 5/10/2013 Other Health Professional Us
Primary
Concomitant
Hyperaesthesia 1/2013 69 Male 154 lb 5/10/2013 Physician Us
Primary
Concomitant
Pruritus 11/7/2011 66 Female 130 lb 5/10/2013 Consumer Us
Primary
Concomitant
Urticaria 1/29/2013 46 Female 5/10/2013 Consumer Us
Primary
Concomitant
Pruritus 54 Female 5/10/2013 Consumer Us
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/2013 60 Female 145 lb 7/17/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 11/6/2012 61 Female 6/5/2013 Consumer Ca
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 5/31/2010 51 Female 6/7/2013 Consumer Ca
Primary
Concomitant
Stomatitis Hospitalization Female 7/11/2013 Consumer Ca
Primary
Secondary
Concomitant
Weight Decreased Other Serious 39 Female 134 lb 8/7/2013 Consumer Us
Primary
Concomitant
Wound Death 6/25/2005 55 Female 8/8/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data