Trastuzumab combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Fracture Other Serious 2/24/2006 29 Female 3/17/2006 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2005 66 Female 117 lb 1/27/2007 Physician Austria
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Other Serious 1/1/2005 75 Female 5/26/2007 Physician Germany
Primary
Concomitant
Thoracic Cavity Drainage Other Serious 1/1/2005 75 Female 5/26/2007 Physician Germany
Primary
Concomitant
Pain In Jaw Other Serious 1/1/2003 47 Female 156 lb 10/13/2007 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 10/9/2007 Female 143 lb 11/9/2007 Belgium
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/17/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 11/20/2007 Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 10/1/2006 54 Female 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2004 60 Female 12/19/2007 Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/26/2007 53 Female 163 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/26/2007 53 Female 163 lb 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/1/2005 Female 172 lb 2/14/2008 Physician Germany
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 4/1/2002 47 Female 156 lb 3/1/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 4/4/2008 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 12/26/2007 53 Female 163 lb 4/17/2008 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/5/2008 Female 132 lb 5/20/2008 Consumer Brazil
Primary
Concomitant
Blood Glucose Increased Other Serious 5/5/2008 Female 132 lb 7/28/2008 Consumer Brazil
Primary
Concomitant
Neuropathy Peripheral Hospitalization 12/26/2007 53 Female 163 lb 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/14/2008 Female 121 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 Female 126 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 73 8/11/2009 Consumer Switzerland
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 10/10/2009 57 Female 117 lb 12/7/2009 Physician United Kingdom
Primary
Concomitant
Tooth Loss Other Serious 10/1/2006 Female 12/28/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 10/1/2006 Female 1/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/26/2007 Female 2/16/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 2/18/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 2/8/2010 Female 126 lb 3/8/2010 Physician Taiwan, Province Of China
Primary
Secondary
Wheezing Other Serious 2/1/1998 Female 126 lb 3/11/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/18/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 3/22/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2007 Female 144 lb 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/25/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 3/26/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 42 Female 4/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 4/15/2010 Other Health Professional United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 4/19/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 2/8/2010 58 Female 123 lb 5/5/2010 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2008 56 Female 5/6/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 5/12/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 5/28/2010 United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/9/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/17/2008 56 Female 6/10/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 6/11/2010 Other Health Professional United States
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/15/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 6/23/2010 Other Health Professional United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 7/8/2010 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 86 Female 7/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 5/24/2010 44 Female 7/14/2010 Physician Finland
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 7/22/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 86 Female 8/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 6/18/2010 44 Female 8/9/2010 Physician Germany
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 8/11/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 8/17/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/20/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 42 Female 8/20/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/17/2008 56 Female 8/23/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 8/25/2010 Other Health Professional United States
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 8/27/2010 United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/14/2010 United States
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 5/24/2010 44 Female 9/16/2010 Physician Finland
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 116 lb 9/27/2010 United States
Primary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 42 Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/16/2010 Other Health Professional United States
Primary
Concomitant
Sequestrectomy Other Serious 59 Female 10/21/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 6/1/2009 59 Female 11/4/2010 Other Health Professional Japan
Primary
Secondary
Weight Increased Other Serious 1/1/2004 38 Female 11/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 12/1/2009 49 Female 137 lb 12/1/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 12/1/2009 49 Female 137 lb 12/13/2010 Physician Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 12/13/2010 Other Health Professional United States
Primary
Concomitant
Wound Complication 1/21/2010 59 Female 115 lb 12/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypoaesthesia Hospitalization 5/24/2010 44 Female 7/14/2010 Physician Finland
Primary
Concomitant
Periodontitis 1/21/2010 59 Female 115 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 12/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 12/31/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 60 Female 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/8/2011 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 60 Female 2/16/2011 Other Health Professional Japan
Primary
Concomitant
Hypocalcaemia Other Serious 1/26/2011 Female 2/23/2011 Physician Japan
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 6/3/2010 39 Female 134 lb 2/25/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 1/14/2011 55 Female 126 lb 3/1/2011 Physician France
Primary
Secondary
Concomitant
Delirium Hospitalization 1/14/2011 55 Female 126 lb 3/9/2011 Physician France
Primary
Secondary
Concomitant
Delirium Hospitalization 1/14/2011 55 Female 126 lb 3/14/2011 Physician France
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 12/1/2009 49 Female 137 lb 3/14/2011 Physician Japan
Primary
Concomitant
Delirium Hospitalization 1/14/2011 55 Female 126 lb 3/15/2011 Physician France
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 4/25/2005 42 Female 3/18/2011 Physician United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2004 38 Female 3/24/2011 Lawyer United States
Primary
Concomitant
Dyspepsia Other Serious 12/1/2005 39 Female 144 lb 3/28/2011 United States
Primary
Secondary
Concomitant
Pericardial Effusion Life Threatening 12/1/2009 49 Female 137 lb 3/31/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 4/25/2005 42 Female 4/6/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Death 11/22/2010 80 Female 176 lb 4/14/2011 Physician Germany
Primary
Concomitant
Radicular Pain Hospitalization 1/1/2004 38 Female 4/26/2011 Physician United States
Primary
Concomitant
Delirium Hospitalization 1/14/2011 55 Female 126 lb 4/26/2011 Physician France
Primary
Secondary
Concomitant
Neck Pain Hospitalization 1/7/2004 43 Female 170 lb 5/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 11/21/2010 80 Female 176 lb 5/4/2011 Physician Germany
Primary
Concomitant
Gingival Swelling Disability 12/29/2010 60 Female 99 lb 5/10/2011 Other Health Professional Japan
Primary
Concomitant
Contact Stomatitis Death 5/6/2010 60 Female 99 lb 6/8/2011 Other Health Professional Japan
Primary
Concomitant
Fall Other Serious 3/29/2011 84 Female 150 lb 6/20/2011 Physician Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 4/25/2005 42 Female 6/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 1/7/2004 43 Female 170 lb 6/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 1/1/2004 38 Female 6/28/2011 United States
Primary
Concomitant
Osteonecrosis Other Serious 1/21/2010 59 Female 115 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Other Serious 3/29/2011 84 Female 150 lb 7/26/2011 Physician Germany
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/29/2011 84 Female 150 lb 7/29/2011 Physician Germany
Primary
Concomitant
Neoplasm Malignant Other Serious Female 8/10/2011 Other Health Professional Japan
Primary
Concomitant
Urine Potassium Increased Hospitalization 12/1/2009 61 Female 8/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Bicarbonate Decreased Hospitalization 12/1/2009 61 Female 8/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Paronychia Other Serious Female 8/22/2011 Other Health Professional Japan
Primary
Concomitant
Productive Cough Death 4/25/2005 42 Female 8/29/2011 Physician United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 12/1/2009 60 Female 86 lb 9/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 12/1/2005 39 Female 144 lb 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 12/1/2009 60 Female 86 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Melanocytic Naevus Other Serious 1/7/2004 43 Female 170 lb 9/30/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemorrhage Death Female 10/21/2011 Other Health Professional Japan
Primary
Concomitant
Brachial Plexopathy Other Serious 4/25/2005 42 Female 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 4/25/2005 42 Female 12/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 70 Female 1/3/2012 Physician Japan
Primary
Secondary
Dizziness Other Serious 1/1/2004 38 Female 1/14/2012 United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2004 38 Female 2/7/2012 Other Health Professional United States
Primary
Concomitant

Drug Data