Trastuzumab combined with Vinorelbine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dermatomyositis Disability 10/1/2006 Female 2/12/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Dermatomyositis Disability 10/1/2006 Female 3/13/2007 United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 6/13/2007 Physician United Kingdom
Primary
Secondary
Renal Failure Acute Death 6/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Loss Other Serious 54 Female 7/4/2007 Japan
Primary
Concomitant
Tachycardia Life Threatening 7/20/2007 26 Female 150 lb 10/23/2007 Physician Italy
Primary
Secondary
Concomitant
Nausea Hospitalization 10/19/2007 41 Female 11/26/2007 Consumer United Kingdom
Primary
Secondary
Tooth Loss Other Serious 10/1/2006 54 Female 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 54 Female 12/4/2007 Japan
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 29 Female 1/18/2008 Other Health Professional United States
Primary
Secondary
Waist Circumference Increased Other Serious 1/1/2004 29 Female 2/15/2008
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 4/1/2002 47 Female 156 lb 3/1/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/14/2005 Female 3/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 4/4/2008 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 5/6/2008 Female 9/12/2008 Physician United Kingdom
Primary
Concomitant
Lymphoedema Other Serious 3/1/2003 57 Female 9/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Lymphoedema Other Serious 3/1/2003 57 Female 10/6/2008 United Kingdom
Primary
Secondary
Ejection Fraction Decreased Other Serious 3/1/2002 57 Female 10/16/2008 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Skin Ulcer Haemorrhage Hospitalization 46 Female 12/31/2008 Other Health Professional Japan
Primary
Secondary
Metastases To Ovary Other Serious 56 Female 1/12/2009 Netherlands
Primary
Secondary
Concomitant
Metastases To Ovary Other Serious 56 Female 1/22/2009 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/28/2009 48 Female 222 lb 1/30/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 2/7/2009 48 Female 222 lb 2/10/2009 Other Health Professional United States
Primary
Secondary
Muscular Weakness Life Threatening 4/18/2009 Female 187 lb 4/29/2009 Consumer United States
Primary
Secondary
Concomitant
Maculopathy Hospitalization 4/13/2009 Female 5/7/2009 Consumer United Kingdom
Primary
Secondary
Rash Other Serious Female 6/2/2009 Consumer United Kingdom
Primary
Secondary
Disease Progression Death 78 Male 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Neoplasm Malignant Death 12/1/2008 60 7/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 64 Female 8/28/2009 Other Health Professional France
Primary
Secondary
Pyrexia Other Serious 1/19/2009 Female 128 lb 9/9/2009 Physician Italy
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/19/2009 Female 128 lb 9/21/2009 Physician Italy
Primary
Secondary
Concomitant
Vomiting Other Serious 48 Female 11/13/2009 Physician United Kingdom
Primary
Secondary
Vomiting Other Serious 48 Female 11/23/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 48 Female 11/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Anaphylactic Shock Life Threatening 11/26/2009 72 Female 12/2/2009 Other Health Professional Japan
Primary
Concomitant
Vomiting Other Serious 48 Female 12/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Anaphylactic Shock Life Threatening 11/26/2009 72 Female 115 lb 12/22/2009 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/11/2006 54 Female 12/23/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 48 Female 12/28/2009 Physician United Kingdom
Primary
Secondary
Tooth Loss Other Serious 10/1/2006 Female 12/28/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 48 Female 12/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Other Serious 48 Female 1/4/2010 Physician United Kingdom
Primary
Secondary
Tooth Loss Other Serious 10/1/2006 Female 1/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 48 Female 1/7/2010 Physician United Kingdom
Primary
Secondary
Varices Oesophageal Other Serious 12/25/2007 Female 146 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious Female 1/22/2010 Other Health Professional Poland
Primary
Secondary
Vomiting Other Serious 48 Female 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 48 Female 3/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Septic Shock Other Serious Female 3/17/2010 Physician United Kingdom
Primary
Secondary
Septic Shock Other Serious 63 Female 3/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Urine Output Decreased Death 63 Female 3/31/2010 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 63 Female 4/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Septic Shock Death 63 Female 4/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Other Serious 57 Female 5/13/2010 Physician Brazil
Primary
Concomitant
Phrenic Nerve Paralysis Other Serious 58 Female 5/14/2010 Physician Lebanon
Primary
Secondary
Rash Other Serious 54 Female 5/20/2010 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 8/23/2010 58 Female 346 lb 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 1/19/2009 53 Female 128 lb 9/8/2010 Physician Italy
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 8/23/2010 58 Female 346 lb 9/10/2010 Physician United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious Female 10/22/2010 Physician Italy
Primary
Concomitant
Septic Shock Death 63 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Myocarditis Hospitalization 7/13/2005 44 Female 119 lb 11/19/2010 Other Health Professional France
Primary
Secondary
Concomitant
Dermatitis Exfoliative Hospitalization Female 132 lb 11/22/2010 Physician United Kingdom
Primary
Secondary
Periodontitis Other Serious 12/1/2009 11/30/2010 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Death Female 117 lb 12/3/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Wound Complication 1/21/2010 59 Female 115 lb 12/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Periodontitis 1/21/2010 59 Female 115 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Asthenia Death 1/31/2011 Other Health Professional Belgium
Primary
Secondary
Pneumonia Death Female 2/7/2011 Belgium
Primary
Secondary
Osteonecrosis Of Jaw Other Serious 59 Female 6/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 59 Female 6/24/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/21/2010 59 Female 115 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death Female 7/28/2011 Physician Algeria
Primary
Secondary
Concomitant
Infected Skin Ulcer Other Serious Female 7/29/2011 Other Health Professional Japan
Primary
Concomitant
Malaise Hospitalization 1/1/2011 48 Female 97 lb 9/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 9/26/2011 Other Health Professional Australia
Primary
Concomitant
Haemorrhage Death Female 10/21/2011 Other Health Professional Japan
Primary
Concomitant
Acute Hepatic Failure Life Threatening 9/14/2011 45 Female 163 lb 12/1/2011 Physician United States
Primary
Concomitant
Neutropenia Other Serious 1/11/2012 Physician United States
Primary
Secondary
Constipation Other Serious Female 1/23/2012 Physician United Kingdom
Primary
Secondary
Constipation Other Serious Female 1/27/2012 Physician United Kingdom
Primary
Secondary
Disease Progression Death 1/31/2012 Physician United States
Primary
Secondary
Constipation Other Serious Female 2/3/2012 Physician United Kingdom
Primary
Secondary
Constipation Other Serious Female 2/9/2012 Physician United Kingdom
Primary
Secondary
Constipation Other Serious Female 2/15/2012 Consumer United Kingdom
Primary
Secondary
Constipation Other Serious Female 2/17/2012 Physician United Kingdom
Primary
Secondary
Constipation Other Serious Female 2/27/2012 Physician United Kingdom
Primary
Secondary
Constipation Other Serious Female 3/6/2012 Physician United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 1/1/2003 44 Female 152 lb 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Ascites Hospitalization 1/1/2003 44 Female 152 lb 4/13/2012 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Hospitalization 55 Female 5/18/2012 Physician United States
Primary
Concomitant
Bone Loss Hospitalization 1/1/2003 44 Female 152 lb 5/30/2012 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/1/2003 44 Female 152 lb 6/1/2012 Physician United States
Primary
Secondary
Concomitant
Oligohydramnios Other Serious 32 Female 6/12/2012 Germany
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious 32 Female 6/18/2012 Other Health Professional Germany
Primary
Secondary
Low Birth Weight Baby Other Serious Female 6/18/2012 Other Health Professional Germany
Primary
Secondary
Bone Pain Other Serious 6/22/2012 Physician United States
Primary
Secondary
Dermatomyositis Other Serious Female 6/29/2012 Consumer United States
Primary
Secondary
Febrile Neutropenia Other Serious 7/10/2012 Other Health Professional Italy
Primary
Secondary
Paronychia Other Serious 1/1/2003 44 Female 152 lb 8/3/2012 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 44 Female 152 lb 8/10/2012 Lawyer United States
Primary
Secondary
Concomitant
Mania Hospitalization 55 Female 8/12/2012 Physician United States
Primary
Concomitant
Respiratory Distress Death Female 12/30/2013 Physician Dz
Primary
Secondary
Concomitant
Prinzmetal Angina Other Serious 6/2011 49 Female 97 lb 8/17/2013 Physician Jp
Primary
Secondary
Concomitant
Oligohydramnios Other Serious 32 Female 9/12/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Oligohydramnios Other Serious 32 Female 8/31/2012 Physician De
Primary
Secondary
Premature Baby Congenital Anomaly Male 8/27/2012 Other Health Professional Us
Primary
Secondary
Neoplasm Malignant Death 10/11/2011 NotSpecified 1/29/2013 Physician De
Primary
Concomitant
Tachyphrenia Other Serious 55 Female 10/23/2012 Other Health Professional Country Not Specified
Primary
Secondary
Liver Disorder Other Serious 5/20/2008 72 Female 12/14/2012 Physician Be
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 5/1/2011 46 Female 150 lb 11/26/2012 Physician Be
Primary
Secondary
Renal Failure Hospitalization 11/4/2012 53 Female 139 lb 11/22/2012 Physician Es
Primary
Secondary
Renal Failure Life Threatening 11/4/2012 53 Female 139 lb 12/10/2013 Physician Es
Primary
Secondary
Superior Vena Cava Syndrome Other Serious 7/2011 Female 1/24/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Other Serious 64 Female 2/11/2013 Physician Dk
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/26/2012 37 Female 202 lb 12/13/2012 Other Health Professional Us
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/2008 Female 2/13/2013 Consumer Dk
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/2012 Female 176 lb 2/18/2013 Physician Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 2/7/2013 Physician Dk
Primary
Secondary
Vomiting Other Serious NotSpecified 2/6/2013 Other Health Professional Country Not Specified
Primary
Secondary
Liver Disorder Other Serious Female 176 lb 2/25/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Liver Disorder Other Serious 7/2012 Female 176 lb 3/1/2013 Physician Dk
Primary
Secondary
Concomitant
Dihydropyrimidine Dehydrogenase Deficiency Other Serious 7/19/2010 59 Female 132 lb 3/11/2013 Physician At
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 5/2013 66 Female 134 lb 9/5/2013 Physician Au
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 6/2012 62 Female 3/6/2013 Physician At
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 11/9/2012 81 Female 143 lb 7/5/2013 Physician Fr
Primary
Secondary
Concomitant
Tumour Necrosis Hospitalization 2/22/2013 59 Female 115 lb 3/15/2013 Physician Ca
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 44 Female 3/18/2013 Other Health Professional Country Not Specified
Primary
Secondary
Metastases To Liver Other Serious 2012 49 Female 3/13/2013 Physician Dk
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/22/2012 39 Female 5/21/2013 Physician Ie
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 3/18/2013 83 Female 106 lb 6/6/2013 Physician Be
Primary
Secondary
Concomitant
Urosepsis Other Serious 5/3/2013 65 Female 174 lb 7/23/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Leukopenia Other Serious 1/14/2013 53 Female 134 lb 5/24/2013 Physician De
Primary
Secondary
Vomiting Other Serious NotSpecified 7/5/2013 Other Health Professional Us
Primary
Secondary
Disease Progression Other Serious 2/25/2013 52 Female 106 lb 6/18/2013 Physician Es
Primary
Concomitant
Metastases To Skin Other Serious 7/2010 54 Female 8/24/2013 Physician At
Primary
Secondary
Neuropathy Peripheral Death Female 8/27/2013 Physician Ie
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious NotSpecified 7/23/2013 Other Health Professional Us
Primary
Secondary
Vomiting Other Serious Female 8/5/2013 Other Health Professional Au
Primary
Secondary
Hypokalaemia Hospitalization 7/16/2013 65 Female 148 lb 9/7/2013 Physician Fr
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 7/2010 Female 8/24/2013 Physician At
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 47 Female 8/30/2013 Country Not Specified
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 9/4/2013 41 Female 130 lb 9/10/2013 Physician Au
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 9/19/2013 Other Health Professional Us
Primary
Secondary
Vision Blurred Other Serious 2003 49 Female 152 lb 8/28/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data