Tramadol Hcl combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pseudomonas Infection Life Threatening 7/4/2003 Male 141 lb 2/28/2006 Physician Austria
Primary
Secondary
Concomitant
Injection Site Cellulitis Hospitalization 1/10/2006 54 Female 2/24/2006 Ireland
Primary
Concomitant
Vitreous Floaters Other Serious 10/15/2005 80 Male 245 lb 1/20/2006 United States
Primary
Concomitant
Pancytopenia Life Threatening 2/27/2006 20 Male 139 lb 4/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/6/2006 65 Male 5/11/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/7/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Required Intervention 4/6/2005 62 Female 150 lb 3/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased 4/1/2006 71 Male 5/24/2006 Consumer United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 5/26/2006 74 Male Pharmacist United States
Primary
Concomitant
Haemoptysis 1/4/2006 83 Female 5/24/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 11/15/2003 Female 143 lb 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Fluid Retention Other Serious 1/1/2006 70 Female 192 lb 7/19/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 55 Female 110 lb 8/25/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 6/19/2006 Male 9/11/2006 Pharmacist United States
Primary
Concomitant
Pancytopenia Life Threatening 8/3/2005 54 Male 126 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 7/1/2006 65 Female 88 lb 10/17/2006 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 7/1/2006 57 Male 172 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Throat Cancer Other Serious 8/3/2006 Male 187 lb 11/15/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Hospitalization 4/1/2006 55 Female 11/16/2006 United Kingdom
Primary
Concomitant
Intervertebral Discitis Hospitalization 6/14/2006 Female 179 lb 12/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 6/4/2005 61 Female 12/5/2006 Physician Sweden
Primary
Concomitant
Intervertebral Discitis Other Serious 6/14/2006 Female 179 lb 12/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Life Threatening 1/3/2007 75 Female 1/8/2007 Pharmacist United States
Primary
Concomitant
Epistaxis Hospitalization 12/11/2006 72 Male 2/16/2007 Pharmacist United States
Primary
Concomitant
Pain Other Serious 66 Male 201 lb 2/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 201 lb 2/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Hospitalization 66 Male 2/20/2007 United Kingdom
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 8/1/2006 88 Female 2/23/2007 Physician Australia
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 66 Male 201 lb 2/23/2007 United Kingdom
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Hospitalization 4/1/2006 55 Female 3/1/2007 United Kingdom
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Decreased Other Serious 12/19/2006 Female 3/13/2007 Physician United Kingdom
Primary
Concomitant
Intervertebral Discitis Other Serious 6/14/2006 Female 179 lb 3/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Drug Interaction Other Serious 3/23/2007 60 Male 4/4/2007 Consumer United States
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Hospitalization 3/1/2007 54 Female 3/26/2007 Physician Peru
Primary
Secondary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/1/2007 63 Male 302 lb 4/30/2007 United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 8/26/2006 64 Female 5/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/1/2007 Male 187 lb 5/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 3/1/2007 54 Female 6/25/2007 Physician Peru
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 66 Male 7/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 8/1/2004 Female 190 lb 7/13/2007 Lawyer United States
Primary
Secondary
Concomitant
Intervertebral Discitis Other Serious 6/14/2006 Female 179 lb 7/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/9/2003 59 Male 7/26/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/23/2006 32 Female 7/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 6/26/2007 55 Male 7/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/26/2007 55 Male 8/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/1/2007 55 Male 8/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hypothyroidism Hospitalization 3/3/2005 58 Female 8/3/2007 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 6/26/2007 55 Male 7/25/2007 United Kingdom
Primary
Secondary
Concomitant
Pulse Absent Life Threatening 7/30/2007 97 Female 143 lb 8/6/2007 Pharmacist United States
Primary
Concomitant
Pain Hospitalization 66 Male 201 lb 8/16/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Hospitalization 66 Male 201 lb 8/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Oral Discomfort Other Serious 4/24/2007 79 Female 120 lb 7/16/2007 United States
Primary
Concomitant
Vomiting Hospitalization 8/21/2007 69 Female 160 lb 8/29/2007 Pharmacist United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 9/2/2007 Female 218 lb 9/24/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 6/26/2007 71 Female 173 lb 9/26/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/24/2007 66 Male 11/15/2007 Physician United Kingdom
Primary
Concomitant
Intraventricular Haemorrhage Life Threatening 10/25/2007 74 Female 11/16/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 11/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death Male 187 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/24/2007 66 Male 11/29/2007 Physician United Kingdom
Primary
Concomitant
Myocardial Ischaemia Death 10/31/2007 Female 183 lb 12/12/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Ototoxicity Other Serious 9/7/2007 70 Male 167 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Pancreatic Mass Other Serious 60 Female 12/20/2007 Pharmacist United States
Primary
Concomitant
Pain 10/2/2007 Male 1/15/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 78 Male 165 lb 1/28/2008 Pharmacist United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/24/2007 1/28/2008 Consumer Australia
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 3/26/2007 Female 110 lb 2/1/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 12/20/2007 2/4/2008 Physician Australia
Primary
Concomitant
Vomiting 1/15/2008 46 Female 163 lb 2/16/2008 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/29/2008 Male 143 lb 2/20/2008 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 2/13/2008 United Kingdom
Primary
Secondary
Concomitant
Subdural Haemorrhage Death Male 187 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/17/2007 Male 2/26/2008 Other Health Professional Australia
Primary
Interacting
Vomiting 1/15/2008 46 Female 163 lb 2/27/2008 United States
Primary
Concomitant
Skeletal Injury Hospitalization 12/28/2007 51 Male 256 lb 3/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/20/2007 Male 3/17/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cerebral Haematoma Death 3/18/2008 55 Female 249 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 4/2/2008 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 3/1/2008 Female 4/3/2008 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 80 Male 4/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Muscle Injury Other Serious 3/20/2008 74 Female 152 lb 5/2/2008 Consumer United States
Primary
Concomitant
Activities Of Daily Living Impaired Other Serious 1/1/2007 Female 282 lb 5/9/2008 United States
Primary
Concomitant
Neutropenia Other Serious 4/12/2008 Female 5/14/2008 Physician Croatia (Local Name: Hrvatska)
Primary
Concomitant
Palpitations Hospitalization 3/1/2008 Female 5/15/2008 Pharmacist United States
Primary
Concomitant
Tongue Biting Death 2/28/2008 90 Female 5/14/2008 Pharmacist United States
Primary
Concomitant
Rash Macular Hospitalization 4/22/2007 36 Male 6/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Joint Swelling 9/1/2007 Female 150 lb 6/12/2008 United States
Primary
Concomitant
Injection Site Pain Male 184 lb 6/12/2008 Physician United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 3/17/2008 77 Male 175 lb 4/30/2008 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 8/29/2007 69 Female 61 lb 6/25/2008 Pharmacist United States
Primary
Concomitant
Haematuria Other Serious 6/3/2003 Male 7/7/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
Gastrointestinal Haemorrhage Other Serious 5/22/2003 Male 7/7/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
Rash Hospitalization 6/15/2008 63 Female 7/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 6/15/2008 63 Female 7/2/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 7/1/2008 72 Female 7/14/2008 Consumer United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Hospitalization 1/1/2007 72 Female 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Glioblastoma Other Serious Female 8/4/2008 Pharmacist United Kingdom
Primary
Concomitant
Tongue Biting Death 2/28/2008 90 Female 7/29/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 239 lb 7/30/2008 Consumer United States
Primary
Concomitant
Flushing 5/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Glioblastoma Other Serious Female 9/5/2008 Pharmacist United Kingdom
Primary
Concomitant
Skin Discolouration Hospitalization 8/22/2008 65 Female 145 lb 9/15/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 54 Female 9/15/2008 Consumer United States
Primary
Concomitant
Nocturia 2/1/2008 Male 9/23/2008 Consumer
Primary
Concomitant
Walking Aid User Hospitalization 83 Male 175 lb 9/25/2008 United States
Primary
Concomitant
Toxic Skin Eruption Hospitalization 2/5/2008 Male 10/16/2008 Consumer Germany
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/1/2007 Female 229 lb 10/14/2008 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2007 Female 229 lb 11/7/2008 Physician United States
Primary
Concomitant
Drug Effect Decreased 1/1/2007 Male 11/18/2008 Consumer
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/11/2008 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain 10/1/2008 Female 12/12/2008 United States
Primary
Concomitant
Urinary Retention Other Serious 11/19/2008 54 Male 12/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Retention Other Serious 11/19/2008 54 Male 12/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 12/18/2008 Consumer United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 1/5/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Effect Decreased 11/1/2008 Male 1/6/2009 Consumer
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 1/15/2009 Consumer United States
Primary
Secondary
Concomitant
Death Other Serious 70 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Effect Decreased 11/1/2008 Male 2/2/2009 Consumer
Primary
Concomitant
Muscle Twitching Other Serious 2/18/2009 77 Female 133 lb 3/4/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/2/2008 62 Female 187 lb 3/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 3/23/2009 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 3/13/2009 Male 206 lb 4/2/2009 United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 4/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 4/22/2009 Consumer United States
Primary
Secondary
Concomitant
Retching Other Serious 11/12/2008 Female 5/8/2009 Consumer United States
Primary
Secondary
Concomitant
Bronchial Carcinoma Other Serious 3/30/2009 Female 5/22/2009 United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 5/29/2009 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Discomfort 5/26/2009 Male 6/1/2009 Consumer
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/9/2009 Female 148 lb 6/22/2009 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2007 53 Male 161 lb 6/23/2009 Lawyer United States
Primary
Concomitant
Self-medication Hospitalization 6/19/2009 73 Male 164 lb 6/22/2009 Pharmacist United States
Primary
Secondary
Nervousness Other Serious Male 160 lb 6/30/2009 Physician United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2005 45 Female 246 lb 7/16/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2004 Female 7/20/2009 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Hospitalization 7/17/2009 60 Male 159 lb 7/20/2009 Pharmacist United States
Primary
Secondary
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant

Drug Data