Toprol-XL combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Projectile Hospitalization 1/31/2006 59 Female 118 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Other Serious 12/22/2005 47 Male 198 lb 2/7/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 2/22/2006 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 2/24/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization 2/12/2006 59 Female 118 lb 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/31/2006 59 Female 118 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious Female 3/11/2006 United States
Primary
Concomitant
Vomiting Projectile Hospitalization 2/12/2006 59 Female 3/6/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/28/2005 55 Male 276 lb 2/27/2006 United States
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization 1/31/2006 59 Female 118 lb 3/20/2006 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/1/2005 76 Female 136 lb 4/13/2006 United States
Primary
Concomitant
Pleural Effusion Hospitalization 4/3/2006 58 Male 192 lb 4/18/2006 Other Health Professional United States
Primary
Concomitant
Tooth Impacted Other Serious 10/1/2004 87 Female 4/27/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 5/5/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/26/2001 Female 125 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 2/4/2005 77 Male 183 lb 5/5/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 6/1/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 6/26/2001 73 Female 126 lb 6/2/2006 Lawyer United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 6/21/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/5/2004 70 Female 6/26/2006 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/1/2005 76 Female 136 lb 7/6/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 6/15/2006 69 Female 174 lb 7/6/2006 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2004 53 Female 8/9/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/15/2006 69 Female 174 lb 8/11/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 9/1/2006 60 Female 10/5/2006 Other Health Professional United States
Primary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 8/21/2006 54 Male 10/18/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/3/2006 58 Male 192 lb 10/31/2006 Other Health Professional United States
Primary
Concomitant
Rib Fracture Hospitalization 7/30/2006 83 Male 156 lb 10/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 4/3/2006 58 Male 192 lb 11/7/2006 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Other Serious Female 11/17/2006 Physician United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion 58 Male 192 lb 11/14/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Projectile Hospitalization 2/12/2006 59 Female 11/15/2006 Physician United States
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Required Intervention 12/22/2005 47 Male 198 lb 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2004 71 Male 160 lb 11/22/2006 Consumer United States
Primary
Concomitant
Toothache Other Serious 5/8/2006 Male 12/21/2006 United States
Primary
Concomitant
Purulent Discharge Other Serious 5/31/2002 70 Female 161 lb 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Packed Red Blood Cell Transfusion Other Serious 8/11/2004 62 Male 8/29/2006 Physician United States
Primary
Concomitant
Ureteric Obstruction Other Serious 5/5/2004 83 Male 8/29/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 54 Male 205 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 1/15/2007 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 121 lb 1/25/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 2/1/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Tooth Malformation Other Serious 12/1/2005 59 Male 2/20/2007 United States
Primary
Concomitant
Tooth Malformation Other Serious 12/1/2005 59 Male 2/20/2007 United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 3/15/2006 73 Female 3/6/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 10/1/2006 79 Female 3/23/2007 United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 10/1/2006 79 Female 4/27/2007 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 10/1/2004 71 Male 160 lb 5/17/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/1999 54 Male 205 lb 6/12/2007 United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 2/12/2006 Female 6/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised 75 Female 170 lb 6/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/9/2007 78 Female 173 lb 6/6/2007 Physician United States
Primary
Secondary
Concomitant
Nausea 2/1/2007 70 Female 210 lb 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2006 78 Female 173 lb 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 3/9/2007 78 Female 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/1/2006 78 Female 173 lb 7/20/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased 9/29/2006 Female 134 lb 7/26/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 10/3/2007 Male 194 lb 10/26/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 Female 8/29/2007 Physician United States
Primary
Concomitant
Pneumonitis Other Serious 10/3/2007 Male 194 lb 12/5/2007 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 12/1/2006 84 Male 12/7/2007 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 9/28/1999 60 Female 121 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 3/15/2006 73 Female 12/4/2007 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 49 Male 130 lb 12/26/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2007 Female 193 lb 1/15/2008 Physician United States
Primary
Secondary
Concomitant
Ureteric Dilatation Other Serious 10/10/2005 66 Male 129 lb 2/12/2008 United States
Primary
Concomitant
Synovitis Other Serious 10/1/2007 85 Female 149 lb 2/16/2008 Consumer United States
Primary
Concomitant
Wound Drainage Other Serious 4/8/2003 57 Female 2/23/2008 Physician United States
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 2/26/2008 Physician United States
Primary
Secondary
Concomitant
Ureteric Dilatation Other Serious 10/10/2005 66 Male 129 lb 3/4/2008 United States
Primary
Concomitant
Wound Drainage Other Serious 4/8/2003 57 Female 181 lb 3/7/2008 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/8/2003 57 Female 181 lb 3/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 12/25/2007 76 Male 4/7/2008 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/8/2003 57 Female 181 lb 4/5/2008 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/19/2007 65 Male 240 lb 5/19/2008 Pharmacist United States
Primary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2007 70 Female 115 lb 6/26/2008 Consumer United States
Primary
Secondary
Concomitant
Vitamin D Deficiency Other Serious 1/1/2007 70 Female 115 lb 7/10/2008 Consumer United States
Primary
Secondary
Concomitant
Wound Decomposition Other Serious 9/1/2003 Male 130 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2008 Male 9/15/2008 Physician United States
Primary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 9/18/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 9/29/2007 67 Female 6/24/2008 Physician United States
Primary
Concomitant
Multiple Myeloma Hospitalization 2/12/2008 50 Male 6/24/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/5/2007 75 Female 84 lb 9/26/2008 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 4/1/2005 Male 10/28/2008 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 4/8/2003 Female 181 lb 10/30/2008 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/1/2005 Male 257 lb 11/15/2008 United States
Primary
Concomitant
Wound Drainage Other Serious 4/8/2003 Female 181 lb 11/21/2008 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Disability 8/1/2008 Female 11/26/2008 Physician United States
Primary
Concomitant
Rash Hospitalization 1/1/2008 Male 12/31/2008 Physician United States
Primary
Concomitant
Toothache Other Serious 4/1/2005 Male 257 lb 1/12/2009 Physician United States
Primary
Concomitant
Toothache Other Serious 4/1/2005 Male 257 lb 1/14/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2002 Male 175 lb 1/19/2009 Physician United States
Primary
Secondary
Concomitant
Gingival Infection Other Serious Female 1/19/2009 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Disability 8/1/2008 Female 1/19/2009 Physician United States
Primary
Concomitant
Purulent Discharge Required Intervention 5/1/2007 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Jaw Disorder Required Intervention 8/1/2003 Male 7/8/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 5/8/2006 Male 198 lb 2/4/2009 Physician United States
Primary
Concomitant
Fatigue 3/31/2008 82 Female 2/24/2009 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 3/11/2009 69 Male 194 lb 3/12/2009 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Other Serious 2/28/2009 Male 206 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Peripheral Motor Neuropathy Other Serious 12/25/2007 76 Male 161 lb 3/30/2009 Physician United States
Primary
Secondary
Concomitant
Urine Leukocyte Esterase Positive Other Serious 12/25/2007 76 Male 161 lb 4/3/2009 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/1/2005 Male 257 lb 4/7/2009 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/18/2009 Male 173 lb 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 2/28/2009 Male 206 lb 4/17/2009 Other Health Professional United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/18/2009 Male 172 lb 4/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/1997 Male 5/1/2009 Physician United States
Primary
Secondary
Concomitant
Vaginal Discharge Other Serious 4/2/2002 Female 125 lb 5/12/2009 United States
Primary
Secondary
Concomitant
Swelling Other Serious 9/20/2005 Male 198 lb 5/14/2009 Physician United States
Primary
Concomitant
Tremor Other Serious 1/1/1997 Male 5/14/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2003 Male 257 lb 5/15/2009 Physician United States
Primary
Concomitant
Vaginal Discharge Other Serious 4/2/2002 Female 125 lb 5/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Other Serious 9/20/2005 Male 198 lb 5/18/2009 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 12/4/2004 Male 198 lb 5/21/2009 Other Health Professional United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 3/18/2009 Male 172 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Discharge Other Serious 4/2/2002 Female 125 lb 5/26/2009 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/1/1997 Male 5/26/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 10/19/1999 Female 5/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 Male 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 4/21/2009 Female 6/2/2009 Physician United States
Primary
Secondary
Concomitant
Vaginal Discharge Other Serious 4/2/2002 Female 125 lb 6/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 7/17/2008 76 Male 176 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 Female 126 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 12/1/2007 Female 7/14/2009 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 Male 7/15/2009 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Lymphadenopathy Death 6/9/2009 Male 245 lb 7/22/2009 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 12/4/2004 Male 198 lb 7/28/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 12/25/2007 76 Male 161 lb 8/18/2009 Physician United States
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 7/17/2008 76 Male 176 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/8/2003 Female 181 lb 9/2/2009 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/8/2003 Female 181 lb 9/17/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/1/2009 47 Male 155 lb 9/9/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/17/2009 Male 10/9/2009 Physician United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 1/1/1997 Male 11/4/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/17/2009 Male 11/5/2009 United States
Primary
Concomitant
Red Cell Distribution Width Increased Other Serious 9/14/2009 Male 324 lb 11/10/2009 United States
Primary
Concomitant
Tooth Infection Other Serious 12/4/2004 Male 198 lb 11/11/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Discharge Other Serious 4/2/2002 Female 125 lb 11/11/2009 United States
Primary
Secondary
Concomitant
Red Cell Distribution Width Increased Other Serious 9/14/2009 Male 324 lb 11/11/2009 United States
Primary
Concomitant

Drug Data