Toprol-XL combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vertigo Other Serious 1/1/1999 59 Female 161 lb 1/19/2006 Physician United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/1999 58 Female 209 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 9/22/2003 87 Female 95 lb 1/23/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 Female 1/30/2006 Pharmacist United States
Primary
Concomitant
Poor Peripheral Circulation Hospitalization 4/20/2005 Male 2/21/2006 Consumer United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Ischaemic Stroke Other Serious 1/1/2001 Male 225 lb 3/1/2006 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 3/13/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 1/1/2000 64 Female 209 lb 3/27/2006 Lawyer United States
Primary
Concomitant
Prostate Examination Abnormal Death 6/22/2004 62 Male 216 lb 3/29/2006 Physician United States
Primary
Concomitant
Syncope Hospitalization 7/29/2002 44 Male 176 lb 3/29/2006 Lawyer United States
Primary
Concomitant
Venous Insufficiency Hospitalization 1/1/2004 43 Female 115 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Speech Disorder Hospitalization 12/10/2001 71 Female 165 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 6/1/2002 51 Male 256 lb 4/20/2006 Physician United States
Primary
Concomitant
Migraine Hospitalization 12/10/2001 71 Female 165 lb 4/25/2006 Physician United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 11/25/2003 43 Female 115 lb 5/1/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2000 40 Female 181 lb 5/2/2006 Lawyer United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 1/1/2001 86 Male 225 lb 5/8/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/1/2001 74 Female 225 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2002 68 Female 240 lb 5/12/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 4/19/2006 Male 271 lb 6/1/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased 6/27/2005 64 Male 277 lb 6/9/2006 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 6/3/2006 Female 101 lb 7/27/2006 Pharmacist United States
Primary
Concomitant
Thrombosis In Device Hospitalization 6/2/2006 36 Female 334 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Chromaturia 4/1/2006 67 Male 230 lb 7/19/2006 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 1/1/2005 80 Female 182 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious Male 271 lb 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 94 Male 5/3/2007 Pharmacist United States
Primary
Concomitant
Dysgeusia 2/4/2007 78 Male 210 lb 7/10/2007 Consumer United States
Primary
Concomitant
Skin Laceration Other Serious 6/1/2007 Female 172 lb 8/29/2007 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 25 Female 10/1/2007 Physician United States
Primary
Concomitant
Hip Fracture Other Serious 72 Female 225 lb 10/3/2007 Physician United States
Primary
Concomitant
Increased Bronchial Secretion 5/1/2007 57 Female 10/26/2007 Consumer United States
Primary
Concomitant
Depression Other Serious 2/1/2008 Male 280 lb 6/16/2008 Physician United States
Primary
Concomitant
Pallor Hospitalization 5/4/2008 78 Male 7/22/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 149 lb 12/17/2008 Physician United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/19/2008 Female 146 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Other Serious 9/19/2008 Female 146 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/1/2007 Female 160 lb 1/9/2009 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 10/24/2008 Female 1/9/2009 Consumer
Primary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 149 lb 2/3/2009 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/18/2007 Female 140 lb 2/6/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 149 lb 3/11/2009 Consumer United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 3/13/2009 Female 137 lb 3/25/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Female 149 lb 4/7/2009 Consumer United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 4/19/2006 67 Male 180 lb 4/22/2009 United States
Primary
Concomitant
Abdominal Pain Upper 81 Male 135 lb 4/30/2009 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 6/1/2005 65 Female 250 lb 5/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 4/1/2006 5/4/2009 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 3/13/2009 Female 137 lb 5/5/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/17/2009 92 Male 156 lb 5/19/2009 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 2/14/2006 Male 150 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Renal Failure Chronic Other Serious Female 6/5/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased Death 1/14/2009 Female 8/7/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 3/13/2009 Female 150 lb 8/10/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 8/9/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Pruritus 3/3/2009 Female 8/22/2009 United States
Primary
Concomitant
Erythema 4/8/2009 Male 8/22/2009 United States
Primary
Concomitant
Palpitations 3/24/2009 Male 8/22/2009 United States
Primary
Concomitant
Flushing 7/1/2009 Male 200 lb 8/23/2009 United States
Primary
Concomitant
Rash 7/6/2009 Male 275 lb 8/23/2009 United States
Primary
Concomitant
International Normalised Ratio Increased 6/10/2009 Female 8/29/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Surgery Death Female 9/11/2009 United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 3/13/2009 Female 150 lb 9/23/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Respiratory Disorder Death 68 Male 9/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/26/2009 Female 174 lb 11/25/2009 United States
Primary
Secondary
Concomitant
Urticaria 7/22/2009 67 Male 11/16/2009 United States
Primary
Concomitant
Peritonitis Bacterial Hospitalization 75 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 81 Female 12/11/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 70 Female 12/11/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 77 Female 12/11/2009 United States
Primary
Concomitant
Tendon Rupture Other Serious 12/1/2009 Male 250 lb 12/29/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 1/1/2007 73 Male 1/19/2010 Lawyer United States
Primary
Concomitant
Tendon Rupture Other Serious 12/1/2009 Male 250 lb 1/21/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Respiratory Failure Other Serious 12/21/2007 64 Male 1/25/2010 Consumer United States
Primary
Secondary
Concomitant
Food Allergy Other Serious 1/1/2009 Female 2/4/2010 Physician United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 12/1/2009 Male 250 lb 2/19/2010 United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/1/1993 Male 185 lb 3/19/2010 Consumer United States
Primary
Concomitant
Interacting
Ventricular Hypokinesia Hospitalization 64 Male 201 lb 3/25/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Tenderness Other Serious 1/1/1993 56 Male 185 lb 4/21/2010 Physician United States
Primary
Concomitant
Interacting
Blood Urea Increased Other Serious 3/5/2010 59 Male 317 lb 5/5/2010 Physician United States
Primary
Concomitant
Tendonitis Other Serious 1/1/1993 56 Male 185 lb 5/7/2010 Physician United States
Primary
Concomitant
Interacting
Weight Increased Hospitalization 4/26/2010 70 5/11/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 2/1/2004 79 Female 150 lb 5/14/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Other Serious 12/10/2007 84 Male 5/17/2010 Lawyer United States
Primary
Concomitant
Insomnia 2/9/2010 63 Male 185 lb 5/17/2010 United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 31 Male 5/11/2010 United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 5/21/2010 78 Female 205 lb 6/2/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization Female 5/28/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma 1/25/2010 60 Male 298 lb 5/11/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 2/1/2004 79 Female 150 lb 6/8/2010 Consumer United States
Primary
Concomitant
Pyrexia 1/1/2008 65 Female 328 lb 6/10/2010 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 40 Male 238 lb 6/9/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/23/2008 59 Male 185 lb 6/29/2010 Lawyer United States
Primary
Concomitant
Weight Fluctuation 1/1/2003 47 Male 245 lb 6/29/2010 Consumer United States
Primary
Concomitant
Interacting
Septic Shock Other Serious 1/12/2008 75 Male 6/28/2010 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2003 64 Female 6/29/2010 United States
Primary
Concomitant
Palpitations 3/23/2008 59 Female 241 lb 6/29/2010 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/1/2008 73 Female 174 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Panic Disorder Other Serious 5/20/2008 75 Female 170 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Hyperhidrosis 10/5/2008 69 Female 134 lb 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged 10/13/2008 66 Male 265 lb 6/29/2010 Other Health Professional United States
Primary
Concomitant
Dyspnoea Female 6/29/2010 Consumer United States
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 7/1/2009 74 Female 128 lb 6/29/2010 Consumer United States
Primary
Concomitant
Tendonitis Other Serious 1/1/1993 56 Male 185 lb 6/30/2010 Physician United States
Primary
Concomitant
Interacting
Drug Ineffective Other Serious 1/1/2007 77 Male 225 lb 7/6/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/22/2010 73 Female 6/30/2010 Consumer United States
Primary
Concomitant
Platelet Count Decreased Male 7/7/2010 United States
Primary
Concomitant
Panic Disorder Other Serious 5/20/2008 75 Female 170 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization Female 7/1/2010 Physician United States
Primary
Concomitant
Weight Increased 1/1/2007 67 Male 7/9/2010 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 5/5/2010 75 Female 154 lb 7/21/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 6/22/2010 73 Female 7/27/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 4/26/2010 70 132 lb 7/29/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2003 64 Female 8/3/2010 United States
Primary
Concomitant
Syncope Other Serious 12/6/2005 72 Male 194 lb 8/9/2010 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2008 64 Female 328 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Strabismus Other Serious 6/1/2010 82 Male 154 lb 8/16/2010 Consumer United States
Primary
Concomitant
Feeling Abnormal Life Threatening Female 8/23/2010 United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 2/1/2008 60 Male 351 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Traumatic Brain Injury Other Serious 8/1/2007 77 Male 9/8/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 6/22/2010 73 Female 9/15/2010 Physician United States
Primary
Concomitant
Syncope Other Serious 12/6/2005 72 Male 194 lb 9/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Paraesthesia 1/1/2010 76 Female 194 lb 9/21/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/6/2005 72 Male 194 lb 9/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/12/2004 72 Male 194 lb 10/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 7/21/2004 57 Male 10/11/2010 Consumer United States
Primary
Concomitant
Throat Irritation 9/30/2010 63 Female 178 lb 10/12/2010 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2010 85 Female 129 lb 10/15/2010 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 74 Male 185 lb 10/18/2010 Consumer United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 10/15/2010 78 Male 10/22/2010 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2010 67 Male 301 lb 10/26/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant

Drug Data