Toprol-XL combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pharmaceutical Product Complaint Other Serious 1/1/2004 45 Female 12/22/2005 Consumer United States
Primary
Concomitant
Mobility Decreased Other Serious 84 Female 12/22/2005 Consumer United States
Primary
Concomitant
Impaired Self-care Other Serious 84 Female 1/11/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2005 79 Female 106 lb 1/24/2006 Physician United States
Primary
Secondary
Concomitant
Rash 54 Male 180 lb 12/7/2005 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 87 Female 130 lb 2/1/2006 United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 12/1/2005 67 Male 207 lb 2/8/2006 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 80 Male 172 lb 2/8/2006 United States
Primary
Concomitant
Spleen Disorder Hospitalization 12/21/2005 77 Male 2/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 63 Male 230 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/1/2005 Female 155 lb 1/20/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/22/2005 79 Female 106 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/1/2006 46 Male 206 lb 3/3/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 9/18/2005 59 Female 2/24/2006 Pharmacist United States
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2006 79 Female 120 lb 2/28/2006 United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 80 Male 172 lb 3/2/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/20/2003 79 Male 225 lb 3/9/2006 Physician United States
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2006 79 Female 120 lb 3/3/2006 United States
Primary
Concomitant
Heart Rate Decreased Other Serious 90 Male 176 lb 3/17/2006 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/1/2006 46 Male 206 lb 3/27/2006 United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 4/4/2006 Physician United States
Primary
Concomitant
Weight Decreased 10/5/2005 70 Female 242 lb 1/20/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 65 Female 3/31/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/1/2006 46 Male 206 lb 4/13/2006 United States
Primary
Secondary
Concomitant
Oral Discomfort 1/1/2005 72 Female 148 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Colon Cancer Other Serious 1/1/2006 81 Female 131 lb 4/11/2006 United States
Primary
Concomitant
Weight Increased Other Serious 10/31/2005 58 Male 186 lb 4/11/2006 United States
Primary
Concomitant
Myocardial Infarction Death 4/24/2004 67 Male 165 lb 4/24/2006 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious Female 4/17/2006 United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 6/3/2002 70 Male 130 lb 4/25/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Cancer Other Serious 1/1/2004 84 Female 125 lb 4/19/2006 Consumer United States
Primary
Concomitant
Hallucination, Visual Other Serious 5/6/2005 Female 12/30/2005 Pharmacist United States
Primary
Concomitant
Rash Pruritic Hospitalization 12/1/2005 84 Female 4/19/2006 United States
Primary
Concomitant
Road Traffic Accident Other Serious 3/20/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2002 76 Male 196 lb 5/9/2006 Lawyer United States
Primary
Concomitant
Hyperhidrosis Other Serious 1/1/2003 47 Female 190 lb 5/10/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2005 80 Male 210 lb 2/24/2006 United States
Primary
Secondary
Concomitant
Middle Insomnia 1/25/2006 68 Female 130 lb 4/3/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 57 Male 226 lb 5/31/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/1/2006 46 Male 206 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Dysgeusia 48 Female 135 lb 4/3/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 8/18/2004 76 Male 176 lb 5/26/2006 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 2/1/2006 76 Female 165 lb 4/20/2006 United States
Primary
Concomitant
Hypoglycaemia Other Serious 56 Male 6/21/2006 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 3/23/2006 39 Female 190 lb 6/27/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 5/27/2006 52 Female 157 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 85 7/6/2006 United States
Primary
Concomitant
Post Procedural Complication Hospitalization 80 Male 156 lb 7/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Joint Swelling 79 Female 7/21/2006 Consumer United States
Primary
Concomitant
Procedural Hypotension Hospitalization 80 Male 156 lb Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2005 67 Male 176 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 9/11/2005 79 Male 159 lb 8/1/2006 Consumer United States
Primary
Concomitant
Suicidal Ideation 5/1/2006 75 Male 190 lb 7/12/2006 Consumer United States
Primary
Concomitant
Blood Pressure Increased Other Serious 12/6/2005 81 Female 165 lb 6/5/2006 Physician United States
Primary
Concomitant
Middle Insomnia 5/16/2006 84 Male 216 lb 7/12/2006 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 6/30/2006 79 Male 167 lb 7/31/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2006 74 Male 218 lb 7/5/2006 United States
Primary
Concomitant
Periorbital Oedema 5/1/2006 72 Male 143 lb 8/29/2006 Consumer United States
Primary
Concomitant
Weight Fluctuation Other Serious 85 Female 130 lb 8/30/2006 United States
Primary
Concomitant
Vomiting 1/1/2005 72 Female 148 lb 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rosacea Disability 6/1/2006 62 Male 170 lb 9/22/2006 Physician United States
Primary
Concomitant
Mental Status Changes Life Threatening 4/27/2006 Female 110 lb 10/5/2006 Pharmacist United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 150 lb 10/16/2006 United States
Primary
Secondary
Concomitant
Eye Operation Other Serious 6/14/2006 75 Male 250 lb 11/30/2006 United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/1/2006 75 Male 220 lb 12/14/2006 United States
Primary
Concomitant
Haematoma Hospitalization 9/13/2006 95 Female 128 lb 11/6/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 8/17/2006 85 Female 11/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 8/14/2006 73 Male 11/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 11/7/2005 77 Male 12/28/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 11/19/2005 71 Male 207 lb 10/4/2006 Other Health Professional United States
Primary
Concomitant
Palpitations 1/1/2006 26 Female 10/24/2006 United States
Primary
Concomitant
Heart Rate Increased 8/1/2006 74 Male 175 lb 10/24/2006 United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2004 66 Male 215 lb 11/16/2006 United States
Primary
Concomitant
Vocal Cord Inflammation Other Serious 8/1/2005 53 Male 205 lb 11/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 1/18/2007 Consumer United States
Primary
Secondary
Concomitant
Confusional State 10/3/2006 83 Female 11/7/2006 Consumer United States
Primary
Concomitant
Weight Decreased Death 8/28/2006 83 Male 205 lb 1/17/2007 Pharmacist United States
Primary
Concomitant
Semen Volume Decreased 4/1/2006 77 Male 11/1/2006 United States
Primary
Concomitant
Erectile Dysfunction 12/1/2005 69 Male 11/1/2006 United States
Primary
Concomitant
Swelling Face Other Serious 1/5/2006 Male 235 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Skin Disorder Other Serious 55 Female 336 lb 1/30/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 82 Female 11/21/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/20/2006 62 Male 2/7/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 9/14/2006 72 Male 2/16/2007 Physician United States
Primary
Concomitant
Drug Ineffective 7/1/2006 77 Female 3/7/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia Male 3/7/2007 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 10/1/2005 Male 215 lb 3/7/2007 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/1/2006 77 Male 198 lb 3/1/2007 Physician United States
Primary
Concomitant
Dry Mouth 8/1/2006 75 Female 12/6/2006 United States
Primary
Concomitant
Pain Other Serious 12/1/2006 Male 170 lb 3/16/2007 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 2/1/2007 76 Male 180 lb 3/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sweat Discolouration 64 Male 3/27/2007 Physician United States
Primary
Concomitant
Hyperhidrosis 62 Male 185 lb 3/27/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/29/2005 Female 3/28/2007 Physician United States
Primary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Urine Flow Decreased 83 Male 162 lb 12/11/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 81 Female 170 lb 11/28/2006 United States
Primary
Concomitant
Fluid Retention 1/11/2006 49 Female 320 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 11/15/2005 73 Male 230 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pain In Extremity 8/1/2006 74 Male 175 lb 1/23/2007 Other Health Professional United States
Primary
Concomitant
Palpitations 1/1/2006 76 Male 198 lb 1/23/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 1/17/2007 63 Female 1/22/2007 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/1/2006 77 Male 198 lb 4/10/2007 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2007 76 Male 180 lb 4/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Life Threatening 3/23/2007 84 Female 188 lb 4/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 11/9/2006 77 Male 224 lb 1/12/2007 Consumer United States
Primary
Concomitant
Heart Rate Increased 12/5/2006 57 Male 1/12/2007 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/2/2007 72 Male 216 lb 3/11/2007 Pharmacist United States
Primary
Concomitant
Dysphonia 8/1/2005 81 Male 150 lb 4/30/2007 Consumer United States
Primary
Concomitant
Thyroid Disorder Other Serious 7/1/2004 Female 220 lb 5/2/2007 Consumer United States
Primary
Secondary
Concomitant
Sleep Talking Hospitalization 12/1/2006 Male 195 lb 5/15/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 74 Male 5/23/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 82 Female 2/22/2007 United States
Primary
Concomitant
Constipation 85 Female 3/20/2007 United States
Primary
Concomitant
Vomiting 8/5/2006 46 Female 177 lb 2/6/2007 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 10/10/2006 81 Male 117 lb 1/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/7/2006 81 Male 132 lb 2/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 5/2/2007 75 Female 5/25/2007 Pharmacist United States
Primary
Concomitant
Hypnopompic Hallucination Other Serious 12/1/2006 70 Female 6/1/2007 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia 11/1/2006 58 Male 175 lb 4/12/2007 Consumer United States
Primary
Concomitant
Hypertension Hospitalization 79 Female 175 lb 6/6/2007 Consumer United States
Primary
Concomitant
Hypersensitivity Hospitalization 7/15/2006 76 Male 197 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Swelling Other Serious 4/1/2007 Female 175 lb 6/18/2007 Consumer United States
Primary
Concomitant
Cerebral Thrombosis Other Serious 8/27/2006 76 Female 251 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Malaise 69 Male 6/22/2007 United States
Primary
Concomitant
Flatulence 11/1/2006 72 Male 250 lb 6/25/2007 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Hospitalization 4/16/2007 73 Male 134 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Rash Pruritic 5/12/2007 54 Female 7/6/2007 Consumer United States
Primary
Concomitant
Vomiting Death 6/18/2007 68 Male 7/9/2007
Primary
Secondary
Skin Laceration Other Serious 6/1/2007 Female 172 lb 7/9/2007 Consumer United States
Primary
Concomitant
Vomiting Death 6/18/2007 68 Male 7/10/2007
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Syncope Death 6/18/2007 68 Male 7/13/2007 Physician United States
Primary
Secondary
Vomiting Hospitalization 6/18/2006 7/17/2007 Physician United States
Primary
Secondary
Sleep Talking Hospitalization 12/1/2006 Male 195 lb 7/27/2007 Consumer United States
Primary
Concomitant
Syncope Death 6/18/2007 68 Male 7/27/2007 Physician United States
Primary
Secondary
International Normalised Ratio Increased Required Intervention 1/27/2007 87 Female 88 lb 5/2/2007 Pharmacist United States
Primary
Concomitant
Subdural Haemorrhage Life Threatening 7/21/2007 81 Male 7/26/2007 Pharmacist United States
Primary
Concomitant
Vena Cava Thrombosis Hospitalization 9/26/2005 31 Female 133 lb 6/8/2007 Physician United States
Primary
Concomitant
Tinnitus 3/1/2007 85 Male 172 lb 7/10/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation 1/1/2005 78 Female 185 lb 7/10/2007 Consumer United States
Primary
Concomitant
Atrial Fibrillation Other Serious Female 8/13/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/28/2007 Male 218 lb 8/13/2007 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/2007 55 Male 8/9/2007 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/8/2007 64 Female 8/14/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Multiple Fractures Other Serious 1/1/2003 Female 181 lb 8/14/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2003 66 Female 215 lb 7/9/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/28/2007 Male 218 lb 8/17/2007 United States
Primary
Secondary
Concomitant

Drug Data