Toprol-XL combined with Vitamin B-12

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Other Serious 1/12/2006 Female 195 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization 1/31/2006 59 Female 118 lb 2/1/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Retention 12/1/2005 Male 2/27/2006 Consumer United States
Primary
Concomitant
Vomiting Projectile Hospitalization 2/12/2006 59 Female 118 lb 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 3/9/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 3/20/2006 Other Health Professional United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 3/8/2005 62 Female 3/22/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 3/29/2006 Other Health Professional United States
Primary
Concomitant
Tinnitus 11/1/2005 63 Male 315 lb 1/20/2006 Consumer United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 1/1/2003 Female 166 lb 4/5/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Decreased Other Serious 1/1/2001 53 Female 185 lb 5/8/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 5/23/2006 Other Health Professional United States
Primary
Concomitant
Dysgeusia 12/15/2005 27 Female 231 lb 4/3/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 6/14/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 Female 166 lb 6/26/2006 Other Health Professional United States
Primary
Concomitant
Tremor 66 Female 194 lb 4/17/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 1/1/2004 70 Female 115 lb 8/1/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 5/1/2006 72 Female 115 lb 8/3/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 Female 166 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Hospitalization 7/13/2006 72 Male 161 lb 8/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Splenic Infarction Other Serious 5/1/2006 72 Female 115 lb 8/3/2006 United States
Primary
Concomitant
Rash 4/1/2006 73 Female 9/6/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 6/8/2006 67 Female 300 lb 7/19/2006 Consumer United States
Primary
Concomitant
Gout 62 Male 10/24/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 10/19/2006 Physician United States
Primary
Secondary
Concomitant
Depression Hospitalization 6/27/2006 47 Male 10/23/2006 Physician United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/27/2006 47 Male 174 lb 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Nightmare Other Serious 11/1/2006 64 Male 11/22/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 12/6/2006 Consumer United States
Primary
Secondary
Concomitant
Multiple Sclerosis Other Serious 9/13/2005 Female 12/13/2006 Physician
Primary
Concomitant
Somnolence Other Serious 5/1/2006 72 Female 115 lb 12/28/2006 Physician United States
Primary
Concomitant
Urine Flow Decreased Male 12/28/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 8/23/2006 77 Female 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 5/3/2006 59 Female 130 lb 6/30/2006 Consumer United States
Primary
Concomitant
Burning Sensation Other Serious 49 Female 165 lb 6/14/2005 United States
Primary
Concomitant
Flatulence Other Serious 1/1/2004 77 Male 152 lb 6/2/2006 United States
Primary
Concomitant
Rash Other Serious 66 Female 2/19/2007 Physician United States
Primary
Concomitant
Cardiomyopathy Other Serious 4/1/2006 50 Male 183 lb 2/21/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 4/13/2006 54 Male 2/28/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Cardiolipin Antibody Positive Other Serious 12/1/2006 Female 197 lb 3/13/2007 Consumer United States
Primary
Concomitant
Dry Skin Other Serious 8/1/2003 66 Female 146 lb 7/23/2004 Physician United States
Primary
Concomitant
Myocardial Infarction Required Intervention 9/1/2005 48 Female 3/31/2006 United States
Primary
Concomitant
Renal Transplant Other Serious 66 Male 240 lb 3/27/2007 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Required Intervention 11/10/2005 65 Female 100 lb 3/31/2006 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 3/29/2005 Female 3/28/2007 Physician United States
Primary
Concomitant
Gingival Pain Other Serious 10/19/2006 81 Female 146 lb 11/28/2006 United States
Primary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Pruritus Other Serious 9/21/2006 80 Male 170 lb 11/28/2006 United States
Primary
Concomitant
Fungal Skin Infection Other Serious 1/1/2004 Female 140 lb 4/18/2007 Consumer United States
Primary
Concomitant
Rectal Prolapse Hospitalization 5/30/2006 79 Female 4/16/2007 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/11/2006 70 Male 5/10/2007 Consumer United States
Primary
Secondary
Concomitant
Tongue Black Hairy Other Serious 5/2/2007 Male 215 lb 5/11/2007 Other Health Professional United States
Primary
Concomitant
Cardiolipin Antibody Positive Other Serious 12/1/2006 Female 197 lb 5/24/2007 Physician United States
Primary
Concomitant
Amnesia Other Serious Male 220 lb 5/31/2007 Physician United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 2/12/2006 Female 6/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 216 lb 6/19/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased 1/1/2003 62 Male 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Salmonellosis Other Serious 7/1/2007 Male 155 lb 7/23/2007 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 7/27/2007 62 Male 8/13/2007 Other Health Professional United States
Primary
Concomitant
Urinary Hesitation Other Serious 5/2/2007 Male 215 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased 68 Male 223 lb 10/4/2007 Consumer United States
Primary
Secondary
Concomitant
Urinary Hesitation Other Serious 5/1/2007 Male 215 lb 10/10/2007 Other Health Professional United States
Primary
Concomitant
Syncope Other Serious 7/27/2007 62 Male 10/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence 6/18/2007 77 Female 9/21/2007 Consumer United States
Primary
Concomitant
Tinnitus 1/1/2007 Female 419 lb 10/23/2007 Physician United States
Primary
Concomitant
Syncope Vasovagal Other Serious 5/18/2007 Male 225 lb 10/31/2007 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Male 301 lb 12/10/2007 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency 9/17/2004 Male 12/15/2007 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 74 Female 12/7/2007 Consumer United States
Primary
Concomitant
Gynaecomastia 4/1/2007 50 Male 12/20/2007 Consumer United States
Primary
Concomitant
Death Other Serious 1/1/2008 Female 1/18/2008 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/26/2008 Female 122 lb 2/8/2008 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 1/16/2008 Female 160 lb 2/12/2008 Physician United States
Primary
Concomitant
No Adverse Event Female 203 lb 2/15/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 166 lb 3/20/2008 Consumer United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 7/27/2007 62 Male 3/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 9/8/2006 Male 3/27/2008 Consumer United States
Primary
Concomitant
Syncope Other Serious 7/27/2007 62 Male 4/13/2008 United States
Primary
Secondary
Concomitant
Flushing 7/18/2007 53 Male 7/24/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 4/11/2008 69 Female 4/28/2008 Pharmacist United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/2/2008 60 Male 176 lb 7/3/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Ulcer Other Serious 4/1/2007 Male 306 lb 7/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Pain 75 Female 229 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/8/2007 76 Female 170 lb 7/29/2008 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/1/2008 Female 291 lb 8/20/2008 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 5/1/2008 76 Female 9/12/2008 Consumer
Primary
Concomitant
Therapeutic Response Unexpected 1/17/2008 58 Female 9/23/2008 Consumer United States
Primary
Secondary
Concomitant
Hypovolaemia Hospitalization 9/23/2008 Male 174 lb 10/6/2008 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/1/2008 Female 291 lb 10/20/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 9/23/2008 Male 174 lb 10/30/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 5/21/2007 Male 134 lb 11/5/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/20/2008 Male 11/7/2008 Physician United States
Primary
Concomitant
Pulmonary Congestion Other Serious Female 140 lb 12/2/2008 Consumer United States
Primary
Concomitant
Dysphagia Other Serious 9/20/2008 Female 100 lb 12/10/2008 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/20/2008 Male 136 lb 12/15/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/2/2008 Female 143 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral 5/2/2008 90 Female 12/16/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 60 Male 12/17/2008 Physician United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 9/19/2008 Female 146 lb 12/24/2008 Physician United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Other Serious 9/19/2008 Female 146 lb 1/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 9/23/2008 82 Female 148 lb 9/23/2008 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/23/2009 85 Male 180 lb 2/4/2009 Pharmacist United States
Primary
Secondary
Concomitant
Wheezing 1/1/2007 55 Male 174 lb 2/18/2009 Consumer United States
Primary
Concomitant
Flushing 1/2/2009 Male 260 lb 2/24/2009 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 187 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 2/18/2009 67 Female 188 lb 3/4/2009 Other Health Professional United States
Primary
Concomitant
Treatment Failure Hospitalization 3/1/2009 67 Female 185 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 2/18/2009 67 Female 185 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Death Death 1/9/2009 Male 3/6/2009 Consumer United States
Primary
Concomitant
Skin Ulcer 12/1/2008 Female 176 lb 3/14/2009 Other Health Professional United States
Primary
Concomitant
Rash Macular 72 Female 3/16/2009 Consumer United States
Primary
Concomitant
Pulmonary Embolism Death Female 213 lb 3/27/2009 Physician United States
Primary
Concomitant
Lacrimation Increased 12/1/2008 77 Female 134 lb 3/29/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 6/21/2003 81 Female 126 lb 3/23/2009 United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/20/2008 Male 136 lb 4/2/2009 Physician United States
Primary
Concomitant
Weight Increased 81 Female 124 lb 4/21/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 68 Male 168 lb 4/17/2009 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/9/2009 Female 4/24/2009 Physician United States
Primary
Concomitant
Vitamin B12 Deficiency 10/1/2007 71 Female 124 lb 4/30/2009 Consumer United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 4/1/2009 62 Female 5/5/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/9/2009 Female 5/13/2009 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 10/20/2008 Male 136 lb 5/21/2009 Physician United States
Primary
Concomitant
Drug Ineffective 71 Male 5/22/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious Female 5/26/2009 Physician United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 6/11/2009 Physician United States
Primary
Concomitant
Swelling 9/1/2008 Female 146 lb 6/12/2009 United States
Primary
Concomitant
Tremor Death 1/1/2009 Male 139 lb 6/26/2009 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization Male 217 lb 6/30/2009 Physician United States
Primary
Concomitant
Kidney Infection Hospitalization 6/4/2009 Male 182 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Kidney Infection Hospitalization 6/4/2009 Male 182 lb 6/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2009 Male 174 lb 7/17/2009 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2009 Male 139 lb 7/20/2009 Physician United States
Primary
Concomitant
Headache Hospitalization 69 Female 163 lb 7/22/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 7/2/2009 57 Male 233 lb 7/16/2009 Pharmacist United States
Primary
Secondary
Concomitant
Multiple Sclerosis 1/1/2009 Female 106 lb 7/23/2009 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 6/25/2008 Male 7/23/2009 Consumer
Primary
Concomitant
Visual Impairment Hospitalization 4/28/2009 Female 165 lb 7/21/2009 Consumer United States
Primary
Concomitant
Headache Hospitalization 69 Female 163 lb 7/22/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/18/2008 68 Male 168 lb 8/6/2009 Physician United States
Primary
Concomitant
Visual Impairment Hospitalization 4/28/2009 Female 165 lb 8/7/2009 Physician United States
Primary
Concomitant
Tremor 3/9/2008 Female 117 lb 8/22/2009 United States
Primary
Concomitant
Rhinorrhoea Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 180 lb 8/22/2009 United States
Primary
Concomitant
Rash 7/6/2009 Male 275 lb 8/23/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/26/2009 Male 182 lb 8/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Irregular Other Serious 1/1/2005 82 Male 150 lb 8/28/2009 Consumer United States
Primary
Secondary
Concomitant

Drug Data