Topamax combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Simple Partial Seizures Other Serious 68 Female 140 lb 1/27/2006 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/1/2005 Female 124 lb 1/20/2006 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 11/23/2003 61 Male 256 lb 3/1/2006 Lawyer United States
Primary
Concomitant
Sinus Bradycardia Other Serious 11/27/2003 61 Male 256 lb 3/30/2006 Physician United States
Primary
Concomitant
Malaise Other Serious 6/1/2006 78 Female 170 lb 6/29/2006 Consumer United States
Primary
Secondary
Concomitant
Medical Device Implantation Hospitalization 5/17/2006 71 Female 170 lb 7/14/2006 Physician United States
Primary
Concomitant
Insomnia 4/1/2006 64 Female 132 lb 7/12/2006 Consumer United States
Primary
Concomitant
Pain Other Serious 56 Female 8/25/2006 Physician United States
Primary
Concomitant
Walking Disability Other Serious 2/1/2006 59 Female 225 lb 7/19/2006 United States
Primary
Concomitant
Tooth Deposit Other Serious 68 Female 151 lb 10/17/2006 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 57 Female 128 lb 8/18/2006 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 5/5/2005 74 Female 11/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 1/16/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 2/10/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 4/18/2007 United States
Primary
Secondary
Concomitant
Stent Placement Other Serious 2/1/2007 51 Female 4/28/2007 United States
Primary
Concomitant
Pneumonia Other Serious 11/18/2006 Female 210 lb 5/14/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 182 lb 5/23/2007 United States
Primary
Concomitant
Stent Placement Other Serious 2/1/2007 51 Female 231 lb 6/12/2007 United States
Primary
Concomitant
Joint Swelling 6/3/2007 36 Female 6/18/2007 Consumer United States
Primary
Concomitant
Insomnia 3/1/2007 45 Male 4/10/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 5/1/2007 195 lb 6/21/2007 Other Health Professional United States
Primary
Concomitant
Troponin I Increased Other Serious 2/19/2007 51 Female 231 lb 6/27/2007 United States
Primary
Concomitant
Injection Site Haemorrhage Other Serious 1/1/2007 Male 7/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2007 Female 191 lb 7/20/2007 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 5/2/2006 Female 140 lb 7/23/2007 Consumer United States
Primary
Concomitant
Keratitis Required Intervention 6/25/2007 48 Female 130 lb 8/6/2007 Other Health Professional United States
Primary
Concomitant
Fatigue 46 Male 351 lb 9/11/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 51 Female 188 lb 9/19/2007 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious 7/12/2007 58 Female 165 lb 10/8/2007 Physician United States
Primary
Concomitant
Hepatic Steatosis Hospitalization 9/25/2007 58 Female 10/8/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 172 lb 10/12/2007 United States
Primary
Concomitant
Injection Site Haemorrhage Hospitalization 2/1/2007 Male 195 lb 10/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
No Adverse Reaction Hospitalization 9/25/2007 58 Female 10/22/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 12/31/2007 Consumer United States
Primary
Secondary
Concomitant
Insomnia Death 54 Female 100 lb 1/14/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Female 181 lb 2/29/2008 Consumer United States
Primary
Concomitant
Oral Surgery Other Serious 1/1/2007 Female 172 lb 3/6/2008 United States
Primary
Concomitant
Blood Glucose Increased Other Serious 6/1/2006 53 Female 239 lb 1/4/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Female 181 lb 5/2/2008 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 5/16/2008 43 Male 240 lb 5/27/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased 2/1/2007 67 Female 220 lb 4/10/2008 Other Health Professional United States
Primary
Concomitant
Sedation Other Serious 5/1/2007 61 Female 7/11/2008 Physician United States
Primary
Concomitant
Interacting
Swelling 3/10/2008 46 Female 7/15/2008 Consumer United States
Primary
Concomitant
Weight Decreased 2/1/2007 67 Female 220 lb 7/7/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/1/2008 Female 109 lb 8/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 9/4/2007 56 Female 155 lb 8/12/2008 Consumer United States
Primary
Concomitant
Sedation Other Serious 5/1/2007 Female 191 lb 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Interacting
Weight Increased 2/1/2007 Female 178 lb 9/23/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 260 lb 11/10/2008 United States
Primary
Concomitant
Tinnitus Hospitalization Male 200 lb 11/10/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 57 Male 240 lb 11/20/2008 United States
Primary
Concomitant
Rash Pruritic 4/11/2008 Male 12/11/2008 Consumer United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 1/1/2007 Female 180 lb 2/20/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1998 Female 168 lb 3/5/2009 Consumer United States
Primary
Concomitant
Periarthritis Hospitalization 1/1/2007 58 Female 3/13/2009 Physician United States
Primary
Concomitant
Periarthritis Hospitalization 1/1/2007 58 Female 3/18/2009 Physician United States
Primary
Concomitant
Vomiting 11/8/2000 50 Female 163 lb 4/2/2009 United States
Primary
Concomitant
Acute Coronary Syndrome Hospitalization 2/19/2009 Female 166 lb 4/7/2009 Other Health Professional United States
Primary
Concomitant
Death Death 3/30/2008 61 Female 5/22/2009 Lawyer United States
Primary
Concomitant
Stent Placement Other Serious 11/1/2008 67 Male 192 lb 5/26/2009 United States
Primary
Secondary
Concomitant
Somnambulism 73 Female 120 lb 6/1/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/24/2009 Female 8/13/2009 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/24/2009 Female 8/13/2009 Physician United States
Primary
Concomitant
Flushing 11/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Pulmonary Congestion Hospitalization 7/10/2007 45 Female 8/28/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/21/2004 46 Male 350 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 49 Female 140 lb 9/23/2009 United States
Primary
Concomitant
Vomiting 11/8/2000 50 Female 163 lb 9/23/2009 United States
Primary
Concomitant
Insomnia 4/9/2009 59 Male 9/24/2009 Physician United States
Primary
Concomitant
Pain Other Serious 1/1/2008 67 Male 9/30/2009 Consumer United States
Primary
Concomitant
Somnolence 10/15/2009 Female 270 lb 11/4/2009 Consumer United States
Primary
Concomitant
Restrictive Pulmonary Disease Death 46 Female 11/20/2009 United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 12/2/2009 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 46 Female 12/8/2009 United States
Primary
Concomitant
Syncope Other Serious 4/22/2005 Female 1/5/2010 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 46 Female 1/12/2010 Lawyer United States
Primary
Concomitant
Injection Site Pain 11/9/2009 Female 190 lb 1/30/2010 United States
Primary
Concomitant
Pain 12/9/2009 Female 190 lb 1/30/2010 United States
Primary
Concomitant
Arteriosclerosis Death 61 Female 220 lb 5/3/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 12/1/2007 48 Female 174 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Anosmia Other Serious 79 Female 6/25/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 70 Female 6/29/2010 Physician United States
Primary
Concomitant
Pneumonia Other Serious 11/18/2006 63 Female 210 lb 7/8/2010 Consumer United States
Primary
Secondary
Concomitant
Death Death Female 250 lb 7/12/2010 United States
Primary
Concomitant
Dry Mouth Female 175 lb 7/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence 9/1/2007 62 Female 175 lb 7/16/2010 Consumer United States
Primary
Concomitant
Myalgia 1/1/1997 64 Male 165 lb 7/30/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 43 Female 472 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 8/5/2008 47 Female 327 lb 8/10/2010 Physician United States
Primary
Concomitant
Urine Flow Decreased 8/28/2009 75 Male 210 lb 8/27/2010 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 9/1/2009 54 Female 165 lb 9/18/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2006 51 Female 215 lb 9/20/2010 United States
Primary
Concomitant
Cardiomyopathy Hospitalization 61 Female 279 lb 9/28/2010 Other Health Professional United States
Primary
Concomitant
Alopecia 6/1/2009 49 Female 118 lb 10/11/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 1/1/2010 62 Female 240 lb 10/12/2010 Consumer United States
Primary
Concomitant
Rib Fracture Other Serious 9/6/2010 60 Female 10/18/2010 Consumer United States
Primary
Concomitant
Epistaxis 64 Female 10/13/2010 Consumer United States
Primary
Concomitant
Paraesthesia Required Intervention 1/23/2008 48 Female 176 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Swelling Other Serious 61 Female 220 lb 12/1/2010 Other Health Professional United States
Primary
Concomitant
Glossitis Other Serious 68 Female 1/13/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 1/1/2008 55 Female 175 lb 1/14/2011 Consumer United States
Primary
Concomitant
Interacting
Loss Of Libido Other Serious 1/1/2008 55 Female 175 lb 1/14/2011 Consumer United States
Primary
Concomitant
Interacting
Dizziness 11/1/2009 40 Female 1/29/2011 Consumer United States
Primary
Concomitant
Pain 12/9/2009 40 Female 190 lb 1/29/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 10/2/2005 52 Female 220 lb 3/23/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 10/2/2005 52 Female 220 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 8/16/2007 54 Female 215 lb 3/31/2011 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2010 55 Female 172 lb 4/12/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 31 Female 201 lb 6/6/2011 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 31 Female 201 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 1/1/2011 20 Male 235 lb 7/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus Female 131 lb 8/6/2011 Consumer United States
Primary
Concomitant
Somnolence Other Serious 8/1/2008 56 Female 141 lb 9/6/2011 Consumer United States
Primary
Secondary
Concomitant
Lip Dry Other Serious 7/3/2011 75 Female 135 lb 8/8/2011 Consumer United States
Primary
Concomitant
Joint Swelling Other Serious 8/1/2008 56 Female 141 lb 9/14/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 10/2/2005 52 Female 220 lb 9/15/2011 Other Health Professional United States
Primary
Concomitant
Obesity 1/1/1998 47 Female 185 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Dizziness Other Serious 8/1/2008 56 Female 141 lb 9/23/2011 Consumer United States
Primary
Secondary
Concomitant
Dental Caries Other Serious 8/16/2011 69 Female 10/10/2011 Consumer United States
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 3/1/2009 82 Female 152 lb 10/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Other Serious Female 10/20/2011 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Other Serious Female 12/2/2011 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/1/2011 60 Female 12/14/2011 Physician United States
Primary
Concomitant
Injection Site Discolouration Other Serious 11/1/2010 46 Female 1/9/2012 Consumer United States
Primary
Concomitant
Emotional Distress Hospitalization 2/15/2010 36 Female 247 lb 2/1/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Injection Site Erythema Other Serious 11/1/2010 47 Female 2/2/2012 Other Health Professional United States
Primary
Concomitant
Nausea 1/1/2000 50 Female 2/29/2012 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 1/1/2012 55 Male 3/1/2012 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/1/2012 55 Female 3/19/2012 Consumer United States
Primary
Concomitant
Injection Site Erythema Other Serious 47 Female 2/16/2012 Other Health Professional United States
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2012 55 Female 4/26/2012 Physician United States
Primary
Concomitant
Vocal Cord Thickening Other Serious 1/1/2012 55 Female 5/17/2012 Physician United States
Primary
Concomitant
Respiratory Failure Death 4/10/2012 54 Male 6/11/2012 Physician United States
Primary
Concomitant
Pain Hospitalization 2/15/2010 36 Female 247 lb 7/13/2012 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 84 Male 220 lb 7/16/2012 Other Health Professional United States
Primary
Concomitant
Dehydration Disability 7/28/2008 61 Female 5/14/2009 Other Health Professional United States
Primary
Concomitant
Myalgia 52 Female 7/18/2012 Consumer United States
Primary
Concomitant
Pain Hospitalization 2/15/2010 36 Female 247 lb 7/25/2012 Consumer United States
Primary
Secondary
Concomitant
Flushing 8/1/2011 60 Male 180 lb 8/3/2012 Consumer United States
Primary
Concomitant
Sleep Disorder Female 365 lb 8/3/2012 Consumer United States
Primary
Concomitant
Injection Site Bruising Female 170 lb 10/24/2012 Other Health Professional Us
Primary
Concomitant
Nephrolithiasis 4/17/2012 70 Female 137 lb 10/25/2012 Physician Us
Primary
Concomitant
Drug Level Increased Other Serious 10/22/2012 54 Female 12/10/2012 Pharmacist Us
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious Female 190 lb 10/31/2012 Consumer Us
Primary
Concomitant
Tremor 5/18/2012 42 Female 12/27/2012 Us
Primary
Secondary
Concomitant
Thyroid Neoplasm 3/8/2012 65 Female 163 lb 1/29/2013 Physician Country Not Specified
Primary
Concomitant
Sneezing 57 Female 179 lb 5/17/2013 Consumer Us
Primary
Concomitant

Drug Data