Topamax combined with Wellbutrin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Blood Triglycerides Increased Other Serious 9/12/2005 46 Male 209 lb 1/9/2006 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 3/27/2001 20 Female 10/4/2001 Physician United States
Primary
Concomitant
Tremor Other Serious 11/21/2005 64 Female 1/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 16 Female 1/27/2006 Consumer United States
Primary
Concomitant
Weight Decreased Female 1/27/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 52 Female 1/27/2006 Consumer United States
Primary
Concomitant
Drug Interaction 1/1/2002 47 Female 266 lb 1/27/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 64 Female 133 lb 1/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 45 Female 2/8/2006 Consumer United States
Primary
Secondary
Concomitant
Insomnia 9/1/2005 Female 1/5/2006 Consumer United States
Primary
Concomitant
Tremor Other Serious 11/21/2005 64 Female 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2005 42 Female 189 lb 2/21/2006 Consumer United States
Primary
Concomitant
Ulcer Other Serious 1/1/2002 Female 161 lb 2/21/2006 Lawyer United States
Primary
Secondary
Concomitant
Tremor Hospitalization 11/21/2005 64 Female 133 lb 2/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vulvovaginal Dryness 4/11/2005 33 Female 2/28/2006 Consumer United States
Primary
Concomitant
Neck Pain 10/1/2005 53 Female 2/28/2006 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 11/21/2005 64 Female 132 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Polyp Hospitalization 7/1/2004 32 Female 252 lb 3/2/2006 United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/14/2005 40 Female 3/7/2006 Consumer United States
Primary
Concomitant
Hallucination, Visual Hospitalization 11/14/2005 40 Female 3/7/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2001 61 Female 187 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/3/2006 41 Female 3/30/2006 Pharmacist United States
Primary
Secondary
Interacting
Ventricular Tachycardia Life Threatening 3/3/2006 41 Female 3/31/2006 Pharmacist United States
Primary
Secondary
Ventricular Tachycardia Life Threatening 3/3/2006 41 Female 4/11/2006 Consumer United States
Primary
Secondary
Ventricular Tachycardia Life Threatening 3/16/2006 41 Female 4/18/2006 Pharmacist United States
Primary
Secondary
Sleep Walking Other Serious 1/1/2000 Female 4/18/2006 Consumer United States
Primary
Concomitant
Sleep Walking Other Serious 1/1/2000 Female 4/19/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Other Serious Female 4/17/2006 United States
Primary
Secondary
Concomitant
Tooth Discolouration Female 4/27/2006 Consumer United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 6/30/2000 Female 231 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 44 Male 181 lb 5/15/2006 Physician United States
Primary
Concomitant
Weight Increased 9/1/2005 52 Female 211 lb 3/23/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Life Threatening 7/4/2005 36 Female 118 lb 5/22/2006 United States
Primary
Secondary
Concomitant
Dysphemia 8/1/2005 46 Female 5/30/2006 Consumer United States
Primary
Concomitant
Oesophageal Disorder 3/1/2006 49 Female 162 lb 4/3/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2005 47 4/20/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2005 56 Female 4/20/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2005 42 Female 168 lb 6/19/2006 Physician United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 7/4/2005 36 Female 118 lb 6/16/2006 United States
Primary
Secondary
Concomitant
Overdose Death 41 Female 7/7/2006 Physician United States
Primary
Concomitant
Uterine Polyp Hospitalization 12/1/2005 32 Female 252 lb 7/14/2006 United States
Primary
Concomitant
Blindness Transient Other Serious 3/31/2006 Female 7/24/2006 Other Health Professional United States
Primary
Concomitant
Migraine Hospitalization 5/20/2006 38 Female 7/28/2006 Consumer United States
Primary
Concomitant
Alcoholism 58 Female 8/10/2006 Consumer United States
Primary
Concomitant
Multiple Drug Overdose Death 41 Female 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 5/1/2006 42 Female 220 lb 7/19/2006 Consumer United States
Primary
Concomitant
Migraine Hospitalization 5/20/2006 38 Female 8/22/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 57 Female 244 lb 7/19/2006 United States
Primary
Concomitant
Weight Increased Other Serious 6/14/2006 51 Female 108 lb 7/19/2006 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 6/1/2005 58 Male 7/14/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 7/4/2005 36 Female 118 lb 9/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Blindness Transient Other Serious 3/31/2006 Female 11/7/2006 Other Health Professional United States
Primary
Concomitant
Dissociation Hospitalization 6/1/2006 16 Female 11/8/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious Female 11/6/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2006 Female 112 lb 11/28/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 1/1/2005 47 Female 8/18/2006 Physician United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 1/1/2005 Female 8/18/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2006 53 Female 160 lb 8/18/2006 Consumer United States
Primary
Concomitant
Insomnia 6/23/2006 34 Female 125 lb 10/11/2006 Consumer United States
Primary
Concomitant
Paraesthesia Unknown 10/11/2006 Physician United States
Primary
Concomitant
Trismus 34 Female 12/29/2006 Physician United States
Primary
Concomitant
Somnolence 55 Male 174 lb 12/29/2006 Consumer United States
Primary
Concomitant
Fatigue 36 Female 12/29/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 7/20/2006 52 Female 198 lb 10/24/2006 Pharmacist United States
Primary
Concomitant
Eructation 9/12/2006 69 Male 10/23/2006 Consumer United States
Primary
Secondary
Concomitant
Arthralgia 1/1/2006 Male 1/29/2007 Physician United States
Primary
Secondary
Migraine Hospitalization 5/20/2006 38 Female 1/30/2007 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/1/2007 41 Female 2/6/2007 Consumer United States
Primary
Concomitant
Blindness Transient Other Serious 3/31/2006 Female 2/26/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 1/1/2001 37 Female 2/28/2007 Consumer United States
Primary
Concomitant
Contusion 34 Female 2/28/2007 Consumer United States
Primary
Concomitant
Weight Increased 52 Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Screen False Positive 1/1/2006 34 Female 3/1/2007 Consumer United States
Primary
Concomitant
Palpitations Other Serious 1/1/2007 41 Female 3/7/2007 Consumer United States
Primary
Concomitant
Weight Decreased Required Intervention 9/10/2006 Female 110 lb 3/9/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2006 41 Female 135 lb 3/13/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 3/23/2007 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 52 Female 131 lb 3/31/2006 Physician United States
Primary
Concomitant
Overdose Disability Female 8/21/2004 United States
Primary
Concomitant
Hallucination, Visual Hospitalization 5/2/2006 52 Female 8/17/2006 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 1/1/2007 48 Female 3/21/2007 Physician United States
Primary
Concomitant
Hyperhidrosis 12/6/2006 36 Male 175 lb 1/12/2007 Consumer United States
Primary
Concomitant
Oesophageal Pain Other Serious 4/5/2007 Female 4/23/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2007 32 Female 4/16/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 28 Female 186 lb 5/1/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Required Intervention 1/1/2007 32 Female 4/24/2007 Physician United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 Female 142 lb 5/4/2007 Consumer United States
Primary
Concomitant
Drug Screen Positive 11/1/2006 34 Female 151 lb 2/6/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/20/2007 46 Female 150 lb 5/11/2007 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 4/20/2007 46 Female 150 lb 5/12/2007 United States
Primary
Concomitant
Suicide Attempt Hospitalization 7/1/2006 33 Female 330 lb 5/24/2007 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2007 52 Female 135 lb 5/30/2007 Consumer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Female 170 lb 6/8/2007 Consumer United States
Primary
Concomitant
Lichen Planus Other Serious Female 6/18/2007 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 30 Female 208 lb 6/18/2007 Physician United States
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 Female 142 lb 7/11/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 32 Female 237 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 12/24/2000 32 Female 220 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Influenza Like Illness Hospitalization 1/1/2006 Male 7/13/2007 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 5/1/2007 25 Female 7/16/2007 United States
Primary
Secondary
Concomitant
Heart Rate Abnormal Other Serious 1/1/2007 36 Female 7/23/2007 Consumer Brazil
Primary
Concomitant
Pitting Oedema 12/1/2006 Female 184 lb 7/26/2007 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2007 Female 200 lb 7/27/2007 Consumer United States
Primary
Concomitant
Swollen Tongue Hospitalization 71 Female 7/25/2007 Physician United States
Primary
Concomitant
Tooth Disorder Hospitalization 1/1/2001 69 Female 9/4/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/1997 33 Female 176 lb 9/12/2007 Consumer United States
Primary
Concomitant
Type 1 Diabetes Mellitus 1/1/2002 15 Male 9/17/2007 United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious Female 252 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Somnolence 1/9/2007 44 Female 9/18/2007 Other Health Professional United States
Primary
Concomitant
Paraesthesia Oral 45 Male 280 lb 9/19/2007 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 5/31/2007 23 Female 130 lb 9/19/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 9/25/2007 United States
Primary
Concomitant
Blindness Other Serious 7/28/2007 Female 10/2/2007 Physician United States
Primary
Concomitant
Nightmare 12/1/2006 9/21/2007 Consumer United States
Primary
Concomitant
Middle Insomnia 1/1/2007 50 Male 300 lb 10/5/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/8/2007 United States
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 69 Female 11/15/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/1/2007 Female 160 lb 11/21/2007 United States
Primary
Concomitant
Tremor Other Serious 3/27/2002 44 Female 250 lb 11/26/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/17/2005 20 Female 261 lb 12/18/2007 Physician United States
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 69 Female 12/18/2007 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 7/9/2007 59 Female 11/20/2007 Consumer United States
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 69 Female 1/23/2008 Physician United States
Primary
Concomitant
Uterine Rupture Other Serious 12/31/2007 40 Female 168 lb 1/28/2008 Other Health Professional United States
Primary
Concomitant
Uterine Rupture Other Serious 12/31/2007 40 Female 168 lb 1/29/2008 Other Health Professional United States
Primary
Concomitant
Paranoia 6/22/2007 46 Male 1/29/2008 Consumer United States
Primary
Concomitant
Throat Tightness 2/1/2007 36 Female 1/29/2008 Consumer United States
Primary
Secondary
Concomitant
Fatigue 4/23/2007 35 Female 1/29/2008 Consumer United States
Primary
Secondary
Rash Female 1/29/2008 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 12/27/2007 32 Female 205 lb 1/30/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 12/24/2000 32 Female 220 lb 2/26/2008 Physician United States
Primary
Concomitant
Suicidal Behaviour Other Serious 51 Female 130 lb 2/24/2008 Lawyer United States
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 69 Female 2/29/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 213 lb 3/13/2008 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 11/1/2006 36 Female 187 lb 3/10/2008 United States
Primary
Concomitant
Muscle Spasms 6/1/2004 33 Female 11/9/2006 Consumer United States
Primary
Concomitant
Systemic Candida Other Serious 2/1/2008 39 Male 248 lb 3/31/2008 Physician United States
Primary
Concomitant
Somnambulism Female 3/31/2008 Physician
Primary
Concomitant
Uterine Disorder Hospitalization 1/1/2001 69 Female 4/1/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 12/1/2007 40 Male 4/14/2008 Consumer United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 7/1/2002 43 Female 135 lb 4/16/2008 Physician United States
Primary
Secondary
Concomitant
Tooth Abscess Hospitalization 5/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 4/15/2008 Female 118 lb 5/1/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 213 lb 5/2/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/6/2008 Physician United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 5/9/2008 Physician United States
Primary
Concomitant
Urticaria Other Serious 5/9/2008 Female 125 lb 5/30/2008 Consumer United States
Primary
Secondary
Concomitant
Depression Other Serious Female 171 lb 6/27/2008 United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 8/1/2003 73 Female 203 lb 7/1/2008 Physician United States
Primary
Concomitant

Drug Data