Topamax combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Traumatic Brain Injury Other Serious 6/1/2006 62 Male 231 lb 11/10/2007 Physician Germany
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 4/21/2009 Female 4/28/2009 Pharmacist United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 4/13/2009 41 Female 215 lb 4/30/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2008 31 Female 6/18/2009 Consumer United States
Primary
Secondary
Concomitant
Therapy Cessation Other Serious 6/1/2008 46 Female 242 lb 6/25/2009 Consumer United States
Primary
Secondary
Concomitant
Product Substitution Issue 40 Female 105 lb 7/23/2009 Consumer United States
Primary
Secondary
Product Substitution Issue 58 Female 317 lb 7/31/2009 United States
Primary
Secondary
Product Substitution Issue Other Serious 8/6/2009 12 Male 118 lb 8/11/2009 United States
Primary
Secondary
Therapy Cessation Other Serious 6/1/2008 Female 242 lb 9/3/2009 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 1/1/2007 Female 149 lb 9/4/2009 Consumer United States
Primary
Secondary
Concomitant
Pruritus Generalised Other Serious 4/21/2009 Female 9/10/2009 Pharmacist United States
Primary
Secondary
Concomitant
Viral Infection Other Serious 1/1/2007 32 Female 170 lb 9/22/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2009 53 Female 9/30/2009 Pharmacist United States
Primary
Secondary
Syncope Hospitalization 4/1/2009 57 Female 210 lb 10/7/2009 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious Female 11/11/2009 Consumer Canada
Primary
Secondary
Concomitant
Product Substitution Issue 2/3/2009 11/19/2009 Consumer United States
Primary
Secondary
Nephrolithiasis Other Serious 1/1/2007 Female 149 lb 11/25/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/1/2009 Female 11/30/2009 Physician United States
Primary
Secondary
Tonic Convulsion Hospitalization Male 154 lb 12/3/2009 Germany
Primary
Concomitant
Thyroxine Increased Other Serious Female 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 1/1/2007 Female 149 lb 1/19/2010 Physician United States
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 54 Female 124 lb 1/23/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/16/2006 Female 172 lb 3/11/2010 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2005 42 Female 4/29/2010 Consumer United States
Primary
Secondary
Concomitant
Product Tampering Other Serious 6/9/2010 Pharmacist United Kingdom
Primary
Secondary
Product Tampering Other Serious 6/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Product Tampering Other Serious 6/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Product Tampering Other Serious 7/1/2010 United Kingdom
Primary
Secondary
Trigeminal Neuralgia Other Serious 1/1/2007 57 Male 232 lb 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Dysarthria Other Serious 14 Female 7/21/2010 Consumer United Kingdom
Primary
Secondary
Dysarthria Other Serious 14 Female 8/11/2010 Consumer United Kingdom
Primary
Secondary
Anaphylactic Reaction Life Threatening 12/1/2009 23 Female 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/1/2009 29 Female 160 lb 8/20/2010 Consumer United States
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 9/24/2010 Consumer United Kingdom
Primary
Secondary
Trigeminal Neuralgia Other Serious 1/1/2007 57 Female 232 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Burning Mouth Syndrome Other Serious 54 Female 10/7/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 5/1/2010 14 Female 10/7/2010 Physician United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 10/11/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 1/1/2000 Female 175 lb 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 10/8/2010 United Kingdom
Primary
Secondary
Vision Blurred Other Serious 5/1/2010 14 Female 10/11/2010
Primary
Secondary
Burning Mouth Syndrome Other Serious 10/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Burning Mouth Syndrome Other Serious 54 Female 10/21/2010
Primary
Secondary
Somnolence Other Serious Female 10/22/2010 Consumer Canada
Primary
Secondary
Concomitant
Vision Blurred Other Serious 5/1/2010 14 Female 11/18/2010 Consumer United Kingdom
Primary
Secondary
Paranoia Other Serious 1/1/2009 33 Male 150 lb 11/22/2010 Consumer United States
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 24 Female 12/10/2010 Pharmacist United Kingdom
Primary
Secondary
Product Substitution Issue Other Serious 24 Female 12/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Product Substitution Issue Other Serious 24 Female 12/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Product Substitution Issue Other Serious 24 Female 12/9/2010 Pharmacist United Kingdom
Primary
Secondary
Vaginal Mucosal Blistering Other Serious 1/1/2000 57 Female 136 lb 12/28/2010 Consumer United States
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 24 Female 12/11/2010 United Kingdom
Primary
Secondary
Product Substitution Issue Other Serious 24 Female 12/14/2010 Pharmacist United Kingdom
Primary
Secondary
Fatigue Other Serious 10/1/2009 62 Female 241 lb 1/4/2011 Consumer United States
Primary
Concomitant
Eye Operation Other Serious Female 1/25/2011 Consumer United States
Primary
Secondary
Feeling Abnormal Other Serious 1/1/2000 57 Female 136 lb 1/31/2011 Consumer United States
Primary
Secondary
Concomitant
Migraine Other Serious 1/1/2009 21 Female 130 lb 2/2/2011 Consumer United States
Primary
Secondary
Pulmonary Embolism Death 1/12/2009 63 Female 112 lb 1/31/2011 Physician Korea, Republic Of
Primary
Concomitant
Migraine Other Serious 1/1/2009 21 Female 130 lb 2/25/2011 Consumer United States
Primary
Secondary
Feeling Abnormal Other Serious 1/1/2000 57 Female 136 lb 3/2/2011 Physician United States
Primary
Secondary
Concomitant
Dry Mouth Other Serious 1/1/2004 Female 3/7/2011 Consumer United States
Primary
Secondary
Concomitant
Pain In Extremity Disability 6/1/2007 32 Female 150 lb 3/14/2011 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 8/16/2009 27 Female 130 lb 3/23/2011 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 8/16/2009 27 Female 130 lb 3/23/2011 Pharmacist United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 1/1/2004 49 Female 175 lb 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Altered State Of Consciousness Other Serious 4/4/2011 37 Female 5/6/2011 Physician Italy
Primary
Concomitant
Asthenia Hospitalization 6/1/2007 32 Female 170 lb 5/10/2011 Consumer United States
Primary
Secondary
Concomitant
Attention Deficit/hyperactivity Disorder Other Serious 1/1/2010 7 Female 75 lb 5/18/2011 Consumer United States
Primary
Secondary
Unevaluable Event Life Threatening 27 Male 170 lb 5/19/2011 Consumer United States
Primary
Secondary
Tracheostomy Other Serious 9/21/2008 16 Female 5/27/2011 Consumer United States
Primary
Secondary
Concomitant
Brain Neoplasm Other Serious 11/1/2006 36 Female 102 lb 5/27/2011 Consumer United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/1/2009 33 Female 240 lb 6/3/2011 Consumer United States
Primary
Secondary
Pulmonary Embolism Hospitalization Female 126 lb 6/6/2011 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 51 Female 156 lb 6/9/2011 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2009 33 Female 240 lb 6/24/2011 Consumer United States
Primary
Secondary
Pruritus 1/1/2008 50 Female 180 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Headache Other Serious 4/1/2009 52 Male 282 lb 6/30/2011 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/1/2009 35 Female 201 lb 7/6/2011 Physician United States
Primary
Secondary
Hypoaesthesia Hospitalization 4/1/2009 54 Male 293 lb 7/8/2011 Consumer United States
Primary
Secondary
Concomitant
Feeling Hot Other Serious 3/1/2011 40 Female 7/19/2011 Consumer Canada
Primary
Secondary
Grand Mal Convulsion Other Serious 1/1/2011 20 Male 235 lb 7/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 4/1/2009 54 Male 7/25/2011 Consumer United States
Primary
Secondary
Concomitant
Food Intolerance Other Serious 28 Female 291 lb 7/14/2011 Consumer United States
Primary
Secondary
Concomitant
Product Substitution Issue Other Serious 8/4/2009 42 Female 148 lb 8/11/2011 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 51 Female 156 lb 8/25/2011 Consumer United States
Primary
Secondary
Concomitant
Impaired Work Ability Other Serious 1/1/2007 36 Female 108 lb 9/9/2011 Consumer United States
Primary
Secondary
Anxiety Hospitalization 1/20/2006 22 Female 235 lb 9/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 1/20/2006 22 Female 235 lb 9/26/2011 Consumer United States
Primary
Secondary
Concomitant
Psychomotor Hyperactivity Other Serious 1/1/2008 46 Female 180 lb 9/30/2011 Consumer United States
Primary
Secondary
Sensory Disturbance Other Serious 1/1/2007 36 Female 108 lb 10/3/2011 Consumer United States
Primary
Secondary
Hypotension Other Serious 9/12/2011 13 Male 77 lb 10/6/2011 Physician Italy
Primary
Secondary
Abnormal Loss Of Weight Other Serious 1/1/2008 46 Female 180 lb 10/10/2011 Consumer United States
Primary
Secondary
Biliary Colic Hospitalization 5/14/2009 24 Female 181 lb 10/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Insomnia Other Serious 1/1/2008 46 Female 180 lb 10/11/2011 Consumer United States
Primary
Secondary
Nervousness Other Serious 1/1/2008 46 Female 180 lb 10/19/2011 Consumer United States
Primary
Secondary
Headache Other Serious 9/12/2011 13 Male 77 lb 10/20/2011 Other Health Professional Italy
Primary
Secondary
Medication Error Other Serious 1/1/2008 46 Female 180 lb 10/27/2011 Consumer United States
Primary
Secondary
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/1/2009 35 Female 150 lb 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Other Serious 10/18/2010 38 Female 11/16/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 8/30/2009 28 Female 178 lb 11/18/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 8/1/2009 49 Female 134 lb 11/18/2011 Consumer United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 8/1/2009 49 Female 134 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Migraine Other Serious 8/6/2011 58 Female 121 lb 11/18/2011 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/20/2006 22 Female 235 lb 11/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal Other Serious 3/1/2011 48 Female 148 lb 12/15/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious Female 134 lb 12/29/2011 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious Female 134 lb 1/19/2012 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 1/1/2005 31 Female 1/24/2012 Consumer United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 1/1/2005 31 Female 1/25/2012 Consumer United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 7/13/2009 25 Female 158 lb 1/26/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dysarthria Hospitalization 10/1/2003 55 Male 185 lb 1/30/2012 Lawyer United States
Primary
Concomitant
Dysgeusia Other Serious 1/26/2012 57 Female 103 lb 2/3/2012 Consumer United States
Primary
Secondary
Petit Mal Epilepsy Other Serious 13 Female 2/9/2012 Consumer United States
Primary
Secondary
Product Quality Issue Other Serious 1/26/2012 57 Female 103 lb 2/16/2012 Consumer United States
Primary
Secondary
Feeling Abnormal Other Serious 1/1/2001 45 Female 140 lb 2/16/2012 Consumer United States
Primary
Secondary
Concomitant
Major Depression Other Serious 1/1/2002 43 Female 232 lb 2/21/2012 Consumer United States
Primary
Secondary
Concomitant
Bipolar Disorder Hospitalization 1/1/2002 43 Female 232 lb 2/27/2012 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/15/2004 43 Female 126 lb 3/6/2012 Other Health Professional United States
Primary
Concomitant
Wound Haemorrhage Other Serious Male 3/2/2012 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 7/13/2009 25 Female 158 lb 3/9/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious Female 134 lb 3/12/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 126 lb 3/23/2012 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2008 32 Female 126 lb 3/26/2012 Consumer United States
Primary
Secondary
Concomitant
Neuralgia Other Serious Female 4/5/2012 Consumer United States
Primary
Secondary
Gallbladder Disorder Hospitalization 4/7/2008 41 Female 240 lb 4/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 4/7/2008 41 Female 240 lb 4/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 1/1/2010 38 Female 270 lb 4/19/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 18 Female 148 lb 4/26/2012 Lawyer United States
Primary
Concomitant
Amnesia Other Serious Female 155 lb 4/27/2012 Consumer United States
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 1/1/2011 76 Female 145 lb 4/30/2012 Consumer United States
Primary
Secondary
Laryngeal Cleft Other Serious 3/10/2010 Female 6 lb 5/17/2012 Consumer United States
Primary
Secondary
Appendicitis Perforated Hospitalization 6/1/2008 32 Female 126 lb 5/17/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Gallbladder Injury Other Serious 24 Female 195 lb 5/23/2012 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 11/1/2011 67 Female 119 lb 5/24/2012 Physician United States
Primary
Concomitant
Nausea Hospitalization 3/1/2012 Female 5/30/2012 Consumer United States
Primary
Secondary
Laryngeal Cleft Congenital Anomaly 3/10/2010 Female 6 lb 5/30/2012 Other Health Professional United States
Primary
Secondary
Deep Vein Thrombosis Hospitalization 4/30/2010 36 Female 202 lb 6/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Compulsive Lip Biting Other Serious Female 160 lb 6/5/2012 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2011 67 Female 119 lb 6/14/2012 Consumer United States
Primary
Concomitant
Adnexa Uteri Cyst Hospitalization 10/4/2009 38 Female 172 lb 6/15/2012 Consumer United States
Primary
Secondary
Concomitant
Brain Injury Hospitalization 12/2/1999 43 Female 181 lb 6/22/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/5/2006 48 Female 159 lb 6/25/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cholecystitis Infective Hospitalization 6/5/2012 55 Female 180 lb 7/3/2012 Physician United States
Primary
Concomitant
Migraine Other Serious 1/1/2008 39 Female 125 lb 7/9/2012 Consumer United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/1987 19 Male 326 lb 7/9/2012 Physician United States
Primary
Secondary
Deep Vein Thrombosis Other Serious 12/1/2009 36 Female 202 lb 7/23/2012 Consumer United States
Primary
Secondary
Concomitant
Fatigue Life Threatening 1/1/2004 46 Female 210 lb 7/27/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data