Tmc114 combined with Truvada

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Death Death 2/3/2006 Male 127 lb 3/20/2006 United States
Primary
Concomitant
Tuberculosis Hospitalization 3/8/2006 Male 289 lb 3/27/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 48 Male 4/11/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/3/2006 Male 131 lb 4/20/2006 Ireland
Primary
Concomitant
Vomiting Life Threatening 3/3/2006 Male 131 lb 4/24/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 4/25/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 5/3/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 5/18/2006 United States
Primary
Concomitant
Ulcer Life Threatening 5/11/2006 Male 128 lb 5/23/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 6/7/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 6/15/2006 Ireland
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 6/28/2006 Ireland
Primary
Concomitant
Renal Impairment Hospitalization 5/22/2006 Male 7/11/2006 United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 8/10/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 8/17/2006 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 9/15/2006 Ireland
Primary
Concomitant
Urticaria Hospitalization 7/20/2006 67 Male 161 lb 10/16/2006 Consumer France
Primary
Concomitant
Sepsis Life Threatening 3/3/2006 Male 131 lb 10/19/2006 Ireland
Primary
Concomitant
Costochondritis Hospitalization 10/2/2006 Male 184 lb 11/17/2006 Ireland
Primary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 12/4/2006 Ireland
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 10/9/2006 Male 172 lb 12/19/2006 Physician France
Primary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 12/20/2006 Ireland
Primary
Concomitant
Interacting
Sepsis Life Threatening 3/3/2006 Male 131 lb 12/20/2006 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 1/11/2007 Ireland
Primary
Concomitant
Urticaria Hospitalization 7/20/2006 47 Male 161 lb 1/19/2007 Consumer France
Primary
Concomitant
Blood Triglycerides Increased Other Serious 11/8/2006 Male 165 lb 2/16/2007 Physician Panama
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 3/19/2007 Physician Australia
Primary
Secondary
Concomitant
Costochondritis Hospitalization 10/2/2006 Male 184 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Cachexia Death 8/22/2006 Male 216 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 6/17/2006 Male 139 lb 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Hospitalization 6/19/2006 Male 116 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 9/6/2006 Male 156 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 3/26/2007 Physician South Africa
Primary
Secondary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Interacting
Herpes Simplex Hospitalization 12/13/2006 Male 4/19/2007 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/20/2006 Male 4/25/2007 Physician Spain
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 5/2/2007 Physician South Africa
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 5/16/2007 Physician Australia
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/3/2007 Male 147 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 Male 5/25/2007 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Male 150 lb 6/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/3/2007 Male 147 lb 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious 11/8/2006 Male 165 lb 6/25/2007 Physician Panama
Primary
Secondary
Concomitant
Idiopathic Urticaria Hospitalization 6/22/2007 Male 7/6/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 Female 175 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 7/31/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 8/2/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 Female 175 lb 8/3/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/15/2007 Female 209 lb 8/28/2007 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 8/15/2007 Female 209 lb 10/1/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 8/15/2007 Female 209 lb 10/9/2007 Physician United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 9/18/2007 Female 209 lb 10/26/2007 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 11/21/2007 United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/31/2007 Male 159 lb 12/3/2007 Australia
Primary
Concomitant
Idiopathic Urticaria Hospitalization 6/22/2007 Male 176 lb 12/21/2007 Physician Italy
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 8/15/2007 Female 209 lb 12/21/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 6/29/2006 Male 175 lb 12/27/2007 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 10/8/2007 Male 154 lb 12/28/2007 Physician Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/21/2007 Male 238 lb 1/3/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 12/21/2007 Male 238 lb 1/21/2008 Physician United States
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 1/28/2008 Ireland
Primary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 1/30/2008 Physician South Africa
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 10/8/2007 Male 154 lb 2/7/2008 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 2/11/2008 Physician South Africa
Primary
Secondary
Concomitant
Transaminases Increased Life Threatening 10/9/2006 Female 167 lb 2/13/2008 South Africa
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 6/12/2007 Male 168 lb 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 3/7/2008 Ireland
Primary
Concomitant
Post Lumbar Puncture Syndrome Hospitalization 1/1/2008 Female 115 lb 3/10/2008 France
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 3/20/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 11/11/2006 Male 3/25/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 6/12/2007 Male 168 lb 3/28/2008 Physician Spain
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/13/2008 Male 159 lb 3/28/2008 Physician Portugal
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 4/1/2008 United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 8/15/2007 Female 209 lb 4/2/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 10/8/2007 Male 154 lb 4/2/2008 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 4/4/2008 Ireland
Primary
Concomitant
Vomiting Hospitalization 3/20/2008 Female 350 lb 4/14/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/20/2008 Female 350 lb 4/14/2008 United States
Primary
Secondary
Concomitant
Diabetic Ketoacidosis Life Threatening 4/13/2008 Male 157 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 6/25/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 8/21/2008 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/7/2006 Male 151 lb 8/29/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/28/2008 Male 148 lb 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 9/25/2008 Ireland
Primary
Concomitant
Pneumonia Hospitalization 8/28/2008 Male 148 lb 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/13/2008 Male 159 lb 10/3/2008 Physician Portugal
Primary
Secondary
Concomitant
Dermatitis Bullous Life Threatening 11/18/2008 Male 176 lb 12/1/2008 Physician Mexico
Primary
Secondary
Concomitant
Dermatitis Bullous Life Threatening 11/18/2008 Male 176 lb 12/5/2008 Physician Mexico
Primary
Secondary
Concomitant
Dermatitis Bullous Life Threatening 11/18/2008 Male 176 lb 12/9/2008 Physician Mexico
Primary
Secondary
Concomitant
Syphilis Hospitalization 11/18/2008 Male 132 lb 12/22/2008 Physician Mexico
Primary
Secondary
Concomitant
Secondary Syphilis Life Threatening 11/18/2008 Male 132 lb 12/22/2008 Ireland
Primary
Concomitant
Secondary Syphilis Life Threatening 11/18/2008 Male 132 lb 12/23/2008 Ireland
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 12/30/2008 United States
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 1/7/2009 United States
Primary
Concomitant
Retinal Detachment Hospitalization 11/5/2008 Male 139 lb 1/23/2009 Germany
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 2/11/2009 United States
Primary
Concomitant
Retinal Detachment Hospitalization 8/1/2008 Male 139 lb 2/18/2009 Germany
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 3/5/2009 United States
Primary
Concomitant
Retinal Detachment Hospitalization 8/1/2008 Male 139 lb 3/19/2009 Germany
Primary
Concomitant
Sinus Bradycardia Hospitalization 2/16/2009 Male 126 lb 3/19/2009 Ireland
Primary
Concomitant
Sinus Bradycardia Life Threatening 2/16/2009 Male 126 lb 4/1/2009 Ireland
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/25/2007 Male 161 lb 4/28/2009 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/25/2007 Male 161 lb 4/28/2009 Physician Canada
Primary
Secondary
Concomitant
Hepatitis Life Threatening 2/16/2009 Male 128 lb 5/12/2009 Ireland
Primary
Concomitant
Hepatitis Life Threatening 2/16/2009 Male 128 lb 5/29/2009 Ireland
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/10/2009 Ireland
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 11/3/2008 Male 191 lb 6/18/2009 United States
Primary
Concomitant
Hepatitis Life Threatening 2/16/2009 Male 128 lb 6/19/2009 Ireland
Primary
Concomitant
Ischaemia Hospitalization 2/20/2007 Male 219 lb 6/24/2009 Ireland
Primary
Concomitant
Arterial Thrombosis Limb Hospitalization 6/16/2009 Male 214 lb 6/26/2009 Ireland
Primary
Concomitant
Leriche Syndrome Hospitalization 6/6/2009 Male 214 lb 7/22/2009 Ireland
Primary
Concomitant
Convulsion Hospitalization 5/5/2009 44 Male 203 lb 7/30/2009 Ireland
Primary
Concomitant
Pericardial Effusion Hospitalization 4/23/2007 Male 131 lb 8/6/2009 Singapore
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 6/6/2009 Male 214 lb 8/7/2009 Ireland
Primary
Concomitant
Sinus Bradycardia Life Threatening 2/16/2009 Male 128 lb 8/14/2009 Ireland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/10/2009 Male 181 lb 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 4/23/2007 Male 131 lb 9/4/2009 Singapore
Primary
Concomitant
Otitis Media Hospitalization 11/22/2008 Female 139 lb 9/10/2009 Guatemala
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 5/5/2009 Male 203 lb 9/21/2009 Ireland
Primary
Concomitant
Pancreatitis Hospitalization 8/10/2009 Male 181 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Subcutaneous Emphysema Hospitalization 5/5/2009 Male 203 lb 10/8/2009 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 10/29/2009 Ireland
Primary
Concomitant
Brugada Syndrome Hospitalization 10/23/2009 Female 139 lb 11/5/2009 Germany
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 11/3/2008 Male 191 lb 11/12/2009 United States
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 5/5/2009 Male 203 lb 11/19/2009 Ireland
Primary
Concomitant
Leriche Syndrome Hospitalization 6/6/2009 Male 214 lb 11/20/2009 Ireland
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/23/2009 Female 139 lb 12/2/2009 Germany
Primary
Concomitant
Vision Blurred Hospitalization 10/23/2009 Female 139 lb 12/11/2009 Germany
Primary
Concomitant
Ventricular Tachycardia Hospitalization 10/29/2009 Female 139 lb 12/18/2009 Germany
Primary
Concomitant
Vascular Procedure Complication Hospitalization 6/16/2009 61 Male 214 lb 4/1/2010 Ireland
Primary
Concomitant
Transaminases Increased Other Serious 10/9/2006 26 Female 167 lb 4/7/2010 Physician South Africa
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 4/5/2011 24 Male 126 lb 4/29/2011 Physician France
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 4/5/2011 24 Male 126 lb 5/31/2011 Physician France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 4/19/2011 41 Male 132 lb 7/7/2011 Physician France
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 48 Male 7/12/2011 Physician United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 4/19/2011 41 Male 132 lb 7/13/2011 Physician France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 4/19/2011 41 Male 132 lb 7/28/2011 Physician France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 5/20/2011 28 Male 194 lb 9/2/2011 Physician France
Primary
Secondary
Concomitant
Septic Shock Life Threatening 6/20/2011 43 Female 168 lb 9/23/2011 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 6/20/2011 43 Female 168 lb 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 6/27/2012 52 Male 130 lb 9/6/2012 Physician Fr
Primary
Secondary
Concomitant

Drug Data