Theophylline combined with Tiotropium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sleep Attacks Hospitalization 3/1/2005 47 Male 1/9/2006 Other Health Professional Netherlands
Primary
Concomitant
Pyrexia Hospitalization 61 Female 6/22/2006 Other Health Professional Germany
Primary
Concomitant
Somnolence 5/1/2006 72 Female 125 lb 7/12/2006 Consumer United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 68 Male 8/25/2006 Physician Portugal
Primary
Concomitant
Physical Assault Hospitalization 5/7/2006 70 Male 9/1/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 5/11/2006 79 Female 154 lb 10/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Neutrophil Count Decreased Death 10/25/2006 75 Male 1/9/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 10/4/2006 58 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 1/1/2004 65 Male 154 lb 2/19/2007 Norway
Primary
Concomitant
Skin Test Positive Other Serious 61 Male 5/4/2007 Germany
Primary
Concomitant
Pallor Hospitalization 5/11/2006 79 Female 154 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Left Ventricular Failure Hospitalization Male 6/26/2007 Germany
Primary
Concomitant
Knee Arthroplasty Hospitalization 7/5/2006 Male 178 lb 7/3/2007 Consumer United States
Primary
Concomitant
Respiratory Disorder Hospitalization 7/5/2006 Male 178 lb 7/23/2007 Consumer United States
Primary
Concomitant
Tachycardia Life Threatening 8/15/2007 69 Male 9/7/2007
Primary
Concomitant
Tachycardia Other Serious 69 Male 9/12/2007 Consumer United Kingdom
Primary
Concomitant
Mental Disorder Other Serious 9/20/2007 36 Female 10/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Hospitalization 73 Female 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 6/15/2007 73 Female 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Life Threatening 12/19/2007 86 Female 1/22/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/21/2005 62 Male 2/29/2008 Other Health Professional Germany
Primary
Secondary
Myalgia Hospitalization 2/27/2008 63 Male 3/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Other Serious 9/1/2007 Female 168 lb 4/4/2008 Physician United Kingdom
Primary
Concomitant
Dyspnoea At Rest Hospitalization 6/7/2008 66 Male 6/18/2008 Consumer Italy
Primary
Concomitant
Sleep Disorder Life Threatening 2/1/2008 60 Male 165 lb 6/23/2008 Physician Germany
Primary
Concomitant
Dyspnoea At Rest Disability 6/7/2008 66 Male 6/25/2008 Consumer Italy
Primary
Concomitant
Resorption Bone Increased Life Threatening 1/1/2008 56 Female 132 lb 8/11/2008 Physician Germany
Primary
Concomitant
Chronic Respiratory Failure Death 72 Male 8/27/2008 Japan
Primary
Concomitant
Resorption Bone Increased Life Threatening 9/1/2007 56 Female 132 lb 9/19/2008 Physician Germany
Primary
Concomitant
Supraventricular Tachycardia Other Serious 8/18/2008 56 Female 150 lb 10/9/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blindness Other Serious 10/3/2008 Male 11/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Blindness Other Serious 10/3/2008 70 Male 11/5/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Chronic Respiratory Failure Death 72 Male 11/20/2008 Japan
Primary
Concomitant
Resorption Bone Increased Life Threatening 9/1/2007 56 Female 132 lb 11/21/2008 Physician Germany
Primary
Concomitant
Blindness Other Serious 10/3/2008 Male 11/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/1/2008 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 9/1/2007 76 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/1/2008 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/4/2008 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/9/2008 Physician United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 11/30/2008 Consumer United Kingdom
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/1/2008 76 Male 12/17/2008 Other Health Professional
Primary
Secondary
Pyrexia Hospitalization 12/5/2008 Male 12/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 12/22/2008 89 Female 119 lb 1/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 75 Male 119 lb 1/27/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/18/2008 75 Male 2/17/2009 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 56 Female 3/20/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Hypotonia Hospitalization 10/1/2008 66 Male 163 lb 3/23/2009 Physician Germany
Primary
Concomitant
Weight Increased Hospitalization 11/1/2008 Male 3/24/2009 Physician France
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/9/2009 60 Male 4/1/2009 Physician United Kingdom
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/3/2009
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 3/10/2009 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/10/2009 Pharmacist Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/15/2009 Pharmacist Japan
Primary
Secondary
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/22/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 4/2/2009 81 Male 220 lb 4/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Hypotonia Hospitalization 10/1/2008 66 Male 163 lb 4/27/2009 Physician Germany
Primary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 75 Male 119 lb 5/28/2009 Physician Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 7/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 2/27/2008 63 Male 10/23/2009 United Kingdom
Primary
Concomitant
Swelling Other Serious 9/1/2007 Female 168 lb 12/2/2009 Physician United Kingdom
Primary
Concomitant
Mental Disorder Other Serious 9/20/2007 36 Female 12/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Somnolence 11/1/2006 57 Female 197 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Mucosal Inflammation Hospitalization 5/7/2010 68 Male 168 lb 8/3/2010 Physician Germany
Primary
Secondary
Concomitant
Blindness Hospitalization 10/3/2008 70 Male 112 lb 8/16/2010 Physician Germany
Primary
Secondary
Concomitant
Postmenopause Other Serious 5/2/2005 49 Female 8/23/2010 United States
Primary
Secondary
Concomitant
Blindness Hospitalization 10/3/2008 70 Male 8/25/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 7/26/2010 72 Male 198 lb 9/1/2010 Other Health Professional Germany
Primary
Concomitant
Tremor Other Serious 5/2/2005 49 Female 10/1/2010 United States
Primary
Secondary
Concomitant
Systemic Inflammatory Response Syndrome Life Threatening 7/26/2010 72 Male 198 lb 10/5/2010 Other Health Professional Germany
Primary
Concomitant
Vomiting Other Serious 5/2/2005 49 Female 10/29/2010 United States
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Wheezing Other Serious 11/3/2010 62 Female 130 lb 11/11/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 11/3/2010 62 Female 130 lb 12/14/2010 Other Health Professional United States
Primary
Concomitant
Bilevel Positive Airway Pressure Death 4/7/2010 80 Male 137 lb 1/27/2011 Physician Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Other Serious 1/1/2009 71 Female 207 lb 3/21/2011 Consumer Germany
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 1/1/2009 64 Male 4/15/2011 Physician Italy
Primary
Secondary
Concomitant
Sideroblastic Anaemia Hospitalization 11/4/2010 84 Male 90 lb 5/3/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Sideroblastic Anaemia Hospitalization 11/4/2010 84 Male 90 lb 5/24/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/2/2005 49 Female 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 72 Male 172 lb 6/2/2011 Physician Germany
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Other Serious 72 Male 172 lb 5/19/2011 Physician Germany
Primary
Concomitant
Malaise Other Serious 5/2/2005 49 Female 6/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vaginal Abscess Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Refractory Anaemia Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Anaemia Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anti-erythropoietin Antibody Positive Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/22/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data