Tenofovir combined with Zidovudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 3/1/2005 27 Male 1/9/2006 Other Health Professional Australia
Primary
Secondary
Thrombocytopenia Life Threatening 10/5/2004 Male 1/20/2006 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 39 Female 2/6/2006 United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/26/2005 50 Male 2/7/2006 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/21/2006 United States
Primary
Concomitant
Viral Mutation Identified Other Serious Female 2/23/2006
Primary
Secondary
Weight Decreased Other Serious 9/1/2004 44 Male 2/24/2006 United States
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/2/2004 Male 3/3/2006 Other Health Professional Mexico
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 2/1/1999 41 Male 3/6/2006 Physician Germany
Primary
Secondary
Concomitant
Orchitis Hospitalization 9/15/2005 38 Male 121 lb 3/9/2006 Physician Belgium
Primary
Concomitant
Death Death 2/3/2006 Male 127 lb 3/20/2006 United States
Primary
Concomitant
Vomiting Other Serious 36 Male 3/22/2006 Consumer United Kingdom
Primary
Secondary
Viral Load Increased Hospitalization 1/30/2002 44 Male 110 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 143 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Glucose-6-phosphate Dehydrogenase Deficiency Hospitalization 10/5/2004 Female 6 lb 3/24/2006 Other Health Professional France
Primary
Secondary
Concomitant
Wound Secretion Hospitalization 1/1/2004 48 Male 154 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2001 Male 143 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/30/2003 40 Male 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1996 40 Male 161 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Gain Poor Other Serious 1/1/2001 Male 181 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 8/14/2000 52 Male 154 lb 3/28/2006 Physician Germany
Primary
Secondary
Weight Decreased Other Serious 5/1/2001 Male 3/28/2006 Physician Germany
Primary
Secondary
Concomitant
Toxoplasmosis Disability 37 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/1996 40 Male 3/29/2006 Physician Germany
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 2/10/2006 46 Male 3/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 36 Male 4/10/2006 Pharmacist United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 10/5/2004 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 1/6/2004 Male 4/17/2006 Other Health Professional Germany
Primary
Secondary
Pyrexia Other Serious 1/1/1998 Male 154 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Vertigo Other Serious 7/1/2003 Male 163 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Nephritis Other Serious 9/1/1997 19 Male 68 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Rales Hospitalization 1/1/2003 Male 196 lb 4/17/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 9/2/2004 Male 5/4/2006 Other Health Professional Mexico
Primary
Concomitant
Tuberculosis Other Serious 1/1/2001 Male 176 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/1999 Male 110 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/1999 50 Male 128 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/1999 Male 134 lb 5/8/2006 Physician Germany
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 5/17/2006 United States
Primary
Concomitant
Viral Mutation Identified Other Serious 5/17/2006
Primary
Secondary
Splenomegaly Other Serious 10/3/2003 Male 5/17/2006 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Other Serious 8/14/2000 52 Male 154 lb 5/23/2006 Physician Germany
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Viral Load Increased Other Serious Male 6/2/2006 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/5/2004 Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Discolouration Congenital Anomaly 1 Female 6/7/2006 Physician United Kingdom
Primary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 6/13/2006 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 10/5/2004 Male 6/14/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Other Serious 37 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 6/30/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 7/6/2006
Primary
Secondary
Premature Baby Other Serious 7/7/2006
Primary
Secondary
Premature Baby Other Serious Female 7/14/2006 Germany
Primary
Secondary
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 7/21/2006 Physician Japan
Primary
Concomitant
Premature Baby Congenital Anomaly Male 8/21/2006 Physician
Primary
Secondary
Premature Baby Other Serious Female 8/21/2006 Germany
Primary
Secondary
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 39 Male 8/30/2006 Physician Thailand
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly Male 9/1/2006 Physician
Primary
Secondary
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Nephrotic Syndrome Other Serious 5/28/2003 Male 9/8/2006 United States
Primary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Pneumonitis Other Serious 9/1/1997 46 Male 10/3/2006
Primary
Secondary
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Tachycardia Life Threatening 1/12/2005 Male 120 lb 10/16/2006 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 10/30/2006
Primary
Secondary
Premature Baby Other Serious 10/30/2006
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 11/1/2006 18 Female 11/7/2006 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/1/2006 18 Female 11/15/2006 Consumer United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/1/2006 18 Female 11/15/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Tremor Hospitalization 50 Female 11/27/2006
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/26/2005 50 Male 11/28/2006 Consumer United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Male 112 lb 11/28/2006 Belgium
Primary
Concomitant
Weight Decreased Other Serious Female 12/6/2006
Primary
Secondary
Mental Status Changes Hospitalization 11/1/2006 18 Female 1/3/2007 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Mental Status Changes Hospitalization 11/1/2006 18 Female 2/9/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 6/17/2005 Male 4/5/2007 Physician Japan
Primary
Concomitant
Subdural Haematoma Other Serious 7/30/2005 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 4/13/2007 Other Health Professional United States
Primary
Secondary
Haemolytic Anaemia Life Threatening 3/7/2007 59 Male 4/16/2007 Pharmacist Spain
Primary
Secondary
Concomitant
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 5/1/2007 Other Health Professional United States
Primary
Secondary
Vertical Infection Transmission Other Serious 5/3/2007
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/10/2007 5/16/2007 Other Health Professional Germany
Primary
Secondary
Hydrocephalus Other Serious 1/10/2007 0 Male 5 lb 5/17/2007 Other Health Professional United States
Primary
Secondary
Subdural Haematoma Other Serious 7/30/2005 Male 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Hydrocephalus Other Serious 1/10/2007 0 Male 5 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 0 Male 6/14/2007 Physician Argentina
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Percutaneous Coronary Intervention Hospitalization 1/1/2007 Male 201 lb 6/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Intermittent Claudication Hospitalization 1/1/2007 Male 201 lb 7/3/2007 Physician Belgium
Primary
Secondary
Concomitant
Percutaneous Coronary Intervention Hospitalization 1/1/2007 Male 201 lb 7/11/2007 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Premature Baby Other Serious 3/1/2007 0 Male 7 lb 7/20/2007 Physician Argentina
Primary
Secondary
Intermittent Claudication Hospitalization 1/1/2007 Male 201 lb 7/25/2007 Ireland
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 10/12/2007 Other Health Professional United States
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/19/2007 Other Health Professional Italy
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/22/2007 Other Health Professional Italy
Primary
Secondary
Pyrexia Other Serious 9/11/2007 45 Male 132 lb 10/31/2007 Consumer United Kingdom
Primary
Concomitant
Meconium In Amniotic Fluid Hospitalization 4/12/2007 Female 1/14/2008 Physician
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 50 Male 1/23/2008 Physician Italy
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 50 Male 1/29/2008 Physician Italy
Primary
Secondary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
Skin Haemorrhage Hospitalization 1/1/2007 Male 130 lb 2/29/2008 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Polydactyly Congenital Anomaly 11/26/2007 Male 6 lb 3/14/2008 United States
Primary
Secondary
Skin Haemorrhage Hospitalization 1/1/2007 35 Male 143 lb 3/17/2008 Physician Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 3/19/2008
Primary
Secondary
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Death Life Threatening 1/12/2005 Male 120 lb 4/11/2008 Brazil
Primary
Secondary
Concomitant
Death Life Threatening 1/12/2005 Male 120 lb 4/14/2008 Brazil
Primary
Secondary
Concomitant
Death Life Threatening 1/12/2005 Male 4/15/2008 Brazil
Primary
Concomitant
Nausea Hospitalization 9/13/2002 Male 5/1/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/5/2008 Brazil
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/7/2008 Male 123 lb 5/12/2008 Brazil
Primary
Secondary
Concomitant
Lipoatrophy Other Serious 1/24/2008 39 Female 5/16/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 5/22/2008 Pharmacist Japan
Primary
Secondary
Concomitant
17-Hydroxyprogesterone Increased Other Serious 1/1/2008 Female 5/23/2008 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 5/30/2008 Brazil
Primary
Secondary
Concomitant
Maternal Death Affecting Foetus Other Serious 1/1/2008 Female 6/3/2008 Physician Canada
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 39 Male 7/10/2008 Other Health Professional United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 4/18/2008 Female 147 lb 7/11/2008 Brazil
Primary
Secondary
Concomitant
Blood Lactic Acid Increased Life Threatening 6/23/2008 Male 180 lb 7/31/2008 Ireland
Primary
Concomitant
Nephropathy Toxic Other Serious 35 Male 7/31/2008 Namibia
Primary
Secondary
Concomitant
Drug Interaction Other Serious 50 Male 8/20/2008 Other Health Professional Mexico
Primary
Concomitant
Interacting
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 9/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 38 Female 9/22/2008 France
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/10/1999 Male 10/3/2008 Physician
Primary
Secondary
Concomitant
Weight Increased Other Serious Male 195 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Blood Lactic Acid Increased Other Serious 6/23/2008 Male 180 lb 10/24/2008 Ireland
Primary
Concomitant
Kaposi's Sarcoma Other Serious 44 Male 11/3/2008 Physician Italy
Primary
Secondary
Concomitant
Lipohypertrophy 12/1/2007 36 Male 11/11/2008 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 41 Male 12/4/2008 Consumer Canada
Primary
Secondary
Varices Oesophageal Other Serious Female 12/11/2008
Primary
Secondary

Drug Data