Tenofovir Disoproxil Fumarate combined with Zidovudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Life Threatening 9/29/2005 Female 1/27/2006 United Kingdom
Primary
Concomitant
Myopathy Disability 6/29/2005 Female 2/17/2006 United Kingdom
Primary
Secondary
Concomitant
Nephritis Other Serious 1/23/2006 Male 2/21/2006 United Kingdom
Primary
Concomitant
Small For Dates Baby Other Serious 44 Female 3/1/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Nephritis Other Serious 1/23/2006 Male 8/1/2006 United Kingdom
Primary
Concomitant
Meconium In Amniotic Fluid Hospitalization Female 6 lb 8/10/2006 Other Health Professional United States
Primary
Concomitant
Osteoarthritis Disability 6/29/2005 Female 8/30/2006 United Kingdom
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 12/27/2006 Female 7 lb 1/18/2007 United States
Primary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 12/27/2006 Female 7 lb 2/5/2007 United States
Primary
Concomitant
Hospitalisation Hospitalization Female 6 lb 2/7/2007 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/1/2005 2/7/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemolytic Anaemia Life Threatening 3/7/2007 59 Male 3/19/2007 Physician Spain
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 41 Male 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Life Threatening 3/7/2007 59 Male 3/21/2007 Pharmacist Spain
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Life Threatening 3/7/2007 59 Male 3/23/2007 Pharmacist Spain
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/19/2006 Male 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Lymphocyte Count Increased Other Serious 41 Male 5/2/2007 United States
Primary
Secondary
Neonatal Respiratory Distress Syndrome Other Serious 12/27/2006 Female 7 lb 6/20/2007 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 8/14/2007 Physician France
Primary
Concomitant
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 8/21/2007 Consumer United Kingdom
Primary
Secondary
Liver Disorder Hospitalization 9/27/2006 Male 8/22/2007 Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/10/2007 8/23/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Apgar Score Low Hospitalization 8/19/2007 Male 6 lb 8/30/2007 Brazil
Primary
Concomitant
Hydrocephalus Other Serious 1/10/2007 0 Male 5 lb 8/30/2007 Other Health Professional United States
Primary
Secondary
Renal Failure Chronic Other Serious 5/25/2004 Male 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Lung Infiltration Hospitalization 7/30/2007 Male 9/10/2007 Germany
Primary
Concomitant
Arteriosclerosis Hospitalization 7/1/2006 Male 201 lb 9/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Muscle Disorder Congenital Anomaly 9/10/2004 Male 7 lb 9/12/2007 Other Health Professional United States
Primary
Secondary
Neonatal Aspiration Hospitalization 8/19/2007 Male 6 lb 9/12/2007 Brazil
Primary
Concomitant
Arteriosclerosis Hospitalization 7/1/2006 Male 201 lb 9/20/2007 Physician Belgium
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 9/10/2004 Male 7 lb 9/20/2007 Other Health Professional United States
Primary
Secondary
Arteriosclerosis Hospitalization 1/1/2007 Male 201 lb 9/26/2007 Ireland
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 9/26/2007 Male 9 lb 11/1/2007 United States
Primary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Premature Baby Other Serious 6/13/2007 Female 7 lb 11/8/2007 United States
Primary
Secondary
Haemoglobin Decreased Hospitalization 10/25/2007 Male 7 lb 11/15/2007 United States
Primary
Secondary
Anaemia Other Serious 9/26/2007 Male 9 lb 11/15/2007 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 12/27/2006 Female 7 lb 11/21/2007 United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 1/10/2007 11/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Bone Pain Other Serious 9/12/2007 Female 11/28/2007 Uganda
Primary
Concomitant
Haemoglobin Decreased Hospitalization 10/25/2007 Male 7 lb 11/28/2007 United States
Primary
Secondary
Hydrocephalus Other Serious 1/10/2007 0 Male 5 lb 11/29/2007 Other Health Professional United States
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Haemoglobin Decreased Hospitalization 10/25/2007 Male 7 lb 12/5/2007 United States
Primary
Secondary
Premature Baby Other Serious 0 Female 2 lb 12/6/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 2 lb 12/6/2007 Netherlands
Primary
Secondary
Haematemesis Other Serious 11/8/2007 Female 12/7/2007 United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 10/25/2007 Male 7 lb 12/11/2007 United States
Primary
Secondary
Weight Decreased Other Serious Male 12/13/2007
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Premature Baby Other Serious Female 12/14/2007 Consumer Netherlands
Primary
Secondary
Haematemesis Other Serious 11/8/2007 Female 12/20/2007 United States
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 7/30/2007 Male 170 lb 12/27/2007 Germany
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Male 1/18/2008 Physician France
Primary
Concomitant
Pneumonia Hospitalization 7/30/2007 Male 170 lb 1/24/2008 Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/14/2003 Male 1/30/2008
Primary
Secondary
Concomitant
Arteriosclerosis Hospitalization 1/1/2007 Male 201 lb 1/31/2008 Ireland
Primary
Concomitant
Premature Baby Other Serious 12/12/2006 Male 2 lb 1/31/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 12/16/2006 Female 2 lb 1/31/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 2 lb 1/31/2008 Netherlands
Primary
Secondary
Polydactyly Congenital Anomaly 11/26/2007 Male 6 lb 2/1/2008 United States
Primary
Secondary
Lipoatrophy Other Serious 1/24/2008 39 Female 2/5/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Glycogen Storage Disease Type I Other Serious 10/5/2004 Female 2/7/2008 United States
Primary
Secondary
Cryptorchism Congenital Anomaly 9/10/2004 Male 7 lb 2/8/2008 Other Health Professional United States
Primary
Secondary
Polydactyly Congenital Anomaly 11/26/2007 Male 6 lb 2/8/2008 United States
Primary
Secondary
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Glycogen Storage Disease Type I Other Serious 10/5/2004 Female 2/18/2008 United States
Primary
Secondary
Glucose-6-phosphate Dehydrogenase Deficiency Hospitalization 10/5/2004 Female 6 lb 2/18/2008 United States
Primary
Secondary
Concomitant
Micrognathia Congenital Anomaly Male 7 lb 2/6/2008 Other Health Professional United States
Primary
Secondary
Polydactyly Congenital Anomaly 11/26/2007 Male 6 lb 2/19/2008 United States
Primary
Secondary
Histiocytosis Haematophagic Death 35 Male 2/25/2008 Other Health Professional Switzerland
Primary
Secondary
Anaemia Other Serious 1/23/2008 Male 8 lb 2/26/2008 United States
Primary
Concomitant
Hepatitis B Other Serious 42 Male 3/3/2008 Consumer Japan
Primary
Secondary
Glucose-6-phosphate Dehydrogenase Deficiency Hospitalization 10/5/2004 Female 6 lb 3/3/2008 United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 9/12/2007 Female 204 lb 4/1/2008 Uganda
Primary
Concomitant
Bone Pain Other Serious 9/12/2007 Female 204 lb 4/8/2008 Uganda
Primary
Concomitant
Bone Pain Other Serious 9/12/2007 Female 204 lb 4/14/2008 Uganda
Primary
Concomitant
Tachycardia Life Threatening 1/12/2005 Male 120 lb 4/21/2008 Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious Unknown 4/22/2008 Consumer United States
Primary
Secondary
Pain Other Serious Unknown 4/22/2008 Physician United States
Primary
Secondary
Mycobacterial Infection Life Threatening 1/12/2005 Male 120 lb 4/29/2008 Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Death Life Threatening 1/12/2005 Male 4/30/2008 Brazil
Primary
Concomitant
Hepatic Steatosis Other Serious 46 Male 4/29/2008 United States
Primary
Secondary
Pneumonia Hospitalization 7/30/2007 Male 163 lb 5/20/2008 Germany
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/30/2007 Male 163 lb 6/3/2008 Germany
Primary
Secondary
Concomitant
Anaemia Other Serious 9/26/2007 Male 9 lb 6/3/2008 United States
Primary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/11/2008 Brazil
Primary
Secondary
Concomitant
Hepatitis E Hospitalization 32 Female 6/6/2008 Germany
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/7/2008 Male 123 lb 6/23/2008 Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/18/2008 Female 147 lb 6/27/2008 Brazil
Primary
Secondary
Concomitant
Renal Impairment Death 7/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Trisomy 21 Death 3/14/2008 7/28/2008 United States
Primary
Secondary
Renal Failure Acute Death 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Death Unknown 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Sepsis Death Unknown 7/31/2008 United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 12/23/2008 Other Health Professional Spain
Primary
Secondary
Lung Neoplasm Malignant Death 12/23/2008 Other Health Professional Spain
Primary
Secondary
Myocardial Infarction Death 12/23/2008 Other Health Professional Spain
Primary
Secondary
Respiratory Distress Hospitalization 12/20/2008 47 Male 3/9/2009 Other Health Professional France
Primary
Secondary
Nasal Cyst Other Serious 55 Male 3/18/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 3/27/2009 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 4/2/2009 Ireland
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 4/7/2009 Other Health Professional France
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 4/14/2009 Ireland
Primary
Concomitant
Myocardial Infarction Other Serious 7/1/2002 48 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/1/2002 48 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 30 Male 4/29/2009 Other Health Professional Canada
Primary
Secondary
Immune Reconstitution Syndrome Other Serious 38 Male 4/30/2009 Other Health Professional Canada
Primary
Secondary
Virologic Failure Hospitalization 7/1/2002 48 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 38 Male 5/5/2009 Other Health Professional Canada
Primary
Secondary
Immune Reconstitution Syndrome Other Serious 30 Male 5/5/2009 Other Health Professional Canada
Primary
Secondary
Virologic Failure Life Threatening 7/1/2002 49 5/5/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 53 Male 5/13/2009 Other Health Professional United States
Primary
Secondary
Paranasal Cyst Other Serious 55 Male 5/26/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Paranasal Cyst Other Serious 55 Male 6/5/2009 Other Health Professional Belgium
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Other Serious Unknown 6/2/2009 Canada
Primary
Secondary
Maternal Drugs Affecting Foetus Other Serious Unknown 6/2/2009 Canada
Primary
Secondary
Weight Increased Other Serious 4/1/2001 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2001 50 Male 190 lb 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Other Serious 5/22/2006 53 Male 7/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 63 Male 7/13/2009 Germany
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 63 Male 7/21/2009 Other Health Professional Germany
Primary
Secondary
Myelodysplastic Syndrome Hospitalization 63 Male 8/3/2009 Other Health Professional Germany
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 7/1/2008 23 Male 8/6/2009 Physician Japan
Primary
Secondary
Pulmonary Hypertension Other Serious 40 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 55 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Neonatal Disorder Hospitalization 25 Male 8/26/2009 United States
Primary
Secondary
Neurological Symptom Hospitalization 0 Male 8/26/2009 United States
Primary
Secondary
Gastroenteritis Hospitalization 0 Female 8/26/2009 United States
Primary
Secondary
Urinary Tract Infection Other Serious 0 Female 8/26/2009 United States
Primary
Secondary
Nervous System Disorder Hospitalization 0 Male 9/10/2009
Primary
Secondary
Maternal Drugs Affecting Foetus Hospitalization 0 Male 9/10/2009
Primary
Secondary
Maternal Drugs Affecting Foetus Hospitalization 0 Female 9/10/2009
Primary
Secondary
Neonatal Disorder Hospitalization 0 Male 9/10/2009
Primary
Secondary
Urinary Tract Infection Other Serious 0 Female 9/10/2009
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 55 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary

Drug Data