Taxotere combined with Trastuzumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Fracture Other Serious 2/24/2006 29 Female 3/17/2006 United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Neutropenic Colitis Life Threatening 3/24/2007 Female 226 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 3/24/2007 Female 226 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Thoracic Cavity Drainage Other Serious 1/1/2005 75 Female 5/26/2007 Physician Germany
Primary
Concomitant
Thoracic Cavity Drainage Other Serious 1/1/2005 75 Female 5/26/2007 Physician Germany
Primary
Concomitant
Rhinorrhoea Other Serious 50 Female 6/28/2007 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 9/25/2007 65 Female 155 lb 10/17/2007 Physician Ireland
Primary
Secondary
Leukoencephalopathy Life Threatening 10/16/2007 Female 11/2/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 10/16/2007 Female 11/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 12/19/2007 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 2/15/2008 Female 2/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 2/15/2008 Female 3/12/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 44 Female 3/17/2008 Consumer United States
Primary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/18/2008 Female 3/21/2008 Belgium
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/1/2008 48 Female 3/20/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/15/2008 Female 3/28/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/18/2008 Female 4/2/2008 Belgium
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 4/4/2008 United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 2/15/2008 Female 4/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 4/11/2008 Female 4/25/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypothyroidism Disability 6/26/2007 48 Female 4/30/2008 Consumer United States
Primary
Secondary
Enterocolitis Hospitalization 4/11/2008 Female 4/30/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Infection Hospitalization 2/18/2008 Female 4/30/2008 Belgium
Primary
Secondary
Concomitant
Hypothyroidism Disability 6/26/2007 Female 5/23/2008 Other Health Professional France
Primary
Secondary
Hypothyroidism Disability 3/11/2008 Female 6/5/2008 Other Health Professional France
Primary
Secondary
Hypothyroidism Disability 3/11/2008 Female 6/9/2008 Other Health Professional France
Primary
Secondary
Viral Infection Hospitalization 2/18/2008 Female 7/8/2008 Belgium
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/19/2008 52 Female 7/15/2008 Other Health Professional France
Primary
Secondary
Enterocolitis Hospitalization 4/3/2008 Female 8/1/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/14/2008 Female 121 lb 8/29/2008 Physician United Kingdom
Primary
Secondary
Neutrophil Count Decreased Hospitalization 4/3/2008 Female 10/21/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 38 Female 11/6/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/20/2008 12/8/2008 Other Health Professional France
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 2/8/2008 60 Female 127 lb 12/22/2008 Japan
Primary
Concomitant
Pregnancy Other Serious 38 Female 3/31/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization Female 4/23/2009 Physician Germany
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 1/1/2009 45 Female 5/6/2009 Consumer China
Primary
Concomitant
Pericardial Effusion Other Serious 1/1/2009 45 Female 5/19/2009 Consumer China
Primary
Concomitant
Skin Exfoliation Other Serious 9/20/2008 Female 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 Female 126 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Neoplasm Malignant Death 12/1/2008 60 7/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 67 Female 250 lb 8/7/2009 Consumer United States
Primary
Secondary
Sepsis Other Serious 63 Female 9/22/2009 Netherlands
Primary
Secondary
Neurotoxicity Hospitalization 8/3/2009 Female 10/5/2009 Consumer United Kingdom
Primary
Secondary
Cholelithiasis Hospitalization 4/1/2004 42 Female 10/12/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 3/15/2004 58 Female 10/15/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 10/3/2009 Female 104 lb 10/26/2009 Physician Taiwan, Province Of China
Primary
Secondary
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 10/29/2009 Other Health Professional France
Primary
Secondary
Neutropenia Hospitalization 10/29/2009 Female 104 lb 11/25/2009 Physician Taiwan, Province Of China
Primary
Secondary
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 11/30/2009 Other Health Professional France
Primary
Secondary
Pulmonary Embolism Other Serious 1/1/2007 44 Female 12/7/2009 Other Health Professional Sweden
Primary
Secondary
Bradycardia Disability 11/26/2009 Female 12/8/2009 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/6/2008 Female 132 lb 12/14/2009 Physician Japan
Primary
Secondary
Myocardial Infarction Death 12/13/2009 Female 110 lb 12/18/2009 Physician Russian Federation
Primary
Secondary
White Blood Cell Count Decreased Other Serious 3/6/2008 Female 132 lb 12/21/2009 Physician Japan
Primary
Secondary
Wound Other Serious 3/29/2007 Female 115 lb 12/22/2009 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 11/26/2009 73 Female 163 lb 12/28/2009 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 2/13/2006 Female 234 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/6/2008 Female 132 lb 12/30/2009 Physician Japan
Primary
Secondary
Bradycardia Life Threatening 11/26/2009 73 Female 163 lb 1/8/2010 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/13/2009 Female 110 lb 1/11/2010 Physician Russian Federation
Primary
Secondary
Sudden Death Death 12/13/2009 Female 110 lb 1/13/2010 Physician Russian Federation
Primary
Secondary
Pulmonary Embolism Hospitalization 6/8/2009 Female 150 lb 1/15/2010 Physician Germany
Primary
Secondary
Dyspnoea Hospitalization 2/13/2006 Female 234 lb 1/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 3/2/2009 46 Female 97 lb 1/27/2010 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 4/1/2008 58 Female 1/29/2010 Other Health Professional France
Primary
Secondary
Wheezing Other Serious 2/1/1998 Female 126 lb 2/8/2010 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 3/29/2007 Female 115 lb 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 2/18/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 1/28/2010 Female 146 lb 2/23/2010 Physician France
Primary
Secondary
Concomitant
Visual Impairment Other Serious 6/1/2009 61 Female 2/24/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/5/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/11/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/18/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 3/22/2010 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Life Threatening 33 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 3/25/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 Female 3/26/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/15/2004 Female 3/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/2/2009 62 Female 4/6/2010 Other Health Professional France
Primary
Secondary
White Blood Cell Count Other Serious 4/25/2005 42 Female 4/7/2010 United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 3/8/2010 50 Female 175 lb 4/13/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 4/15/2010 Other Health Professional United States
Primary
Concomitant
Bradycardia Life Threatening 11/26/2009 73 Female 163 lb 4/16/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 5/7/2010 United States
Primary
Secondary
Concomitant
Ulcerative Keratitis Other Serious 2/20/2010 51 Female 5/10/2010 Other Health Professional Spain
Primary
Secondary
Alopecia Disability 1/1/2008 39 Female 5/25/2010 Physician France
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 5/28/2010 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization Female 6/1/2010 Physician Germany
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/9/2010 United States
Primary
Concomitant
Skin Toxicity Hospitalization 4/13/2010 71 Female 6/10/2010 Physician Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 6/11/2010 Other Health Professional United States
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/15/2010 United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 5/21/2010 51 Female 6/23/2010 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 6/23/2010 Other Health Professional United States
Primary
Concomitant
Scleroderma Other Serious 7/1/2003 37 Female 6/24/2010 Japan
Primary
Secondary
Tumour Invasion Other Serious 11/30/2005 48 Female 7/8/2010 United States
Primary
Concomitant
Pyrexia Other Serious 6/26/2010 51 Female 109 lb 7/10/2010 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 6/16/2010 75 Female 185 lb 7/12/2010 Consumer Germany
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Other Serious 6/25/2010 36 Female 134 lb 7/13/2010 Physician Philippines
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/17/2010 51 Female 109 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 4/1/2008 58 Female 7/28/2010 Other Health Professional France
Primary
Secondary
Suicide Attempt Other Serious 4/29/2010 65 Female 7/28/2010 Physician Switzerland
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2010 32 Female 7/29/2010 Physician Germany
Primary
Secondary
Suicide Attempt Other Serious 4/29/2010 65 Female 7/29/2010 Physician Switzerland
Primary
Secondary
Concomitant
Fatigue Other Serious 6/25/2010 36 Female 134 lb 8/2/2010 Physician Philippines
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/17/2010 70 Female 8/4/2010 Physician Italy
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 7/17/2010 70 Female 8/17/2010 Physician Italy
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 8/20/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Other Serious 4/25/2005 42 Female 8/20/2010 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/23/2010 54 Female 130 lb 8/23/2010 Physician United States
Primary
Secondary
Fatigue Other Serious 6/25/2010 36 Female 134 lb 8/23/2010 Physician Philippines
Primary
Secondary
Concomitant
Recall Phenomenon Other Serious 74 Female 8/23/2010 Other Health Professional France
Primary
Secondary
Weight Increased Other Serious 1/1/2004 38 Female 8/25/2010 Other Health Professional United States
Primary
Concomitant
Mucosal Inflammation Other Serious 8/1/2010 Female 8/26/2010 Pharmacist Australia
Primary
Secondary
Tumour Invasion Other Serious 11/30/2005 48 Female 8/27/2010 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 7/23/2010 54 Female 135 lb 8/30/2010 Physician United States
Primary
Secondary
Interstitial Lung Disease Hospitalization 8/1/2010 66 Female 9/1/2010 Physician Japan
Primary
Secondary
Tooth Fracture Hospitalization 6/9/2010 35 Female 161 lb 9/2/2010 Other Health Professional Ireland
Primary
Concomitant
Tooth Fracture Hospitalization 6/9/2010 35 Female 161 lb 9/9/2010 Other Health Professional Ireland
Primary
Concomitant
Death Death 8/20/2010 72 Female 192 lb 9/10/2010 Physician Germany
Primary
Secondary
Concomitant
Flushing Life Threatening 9/3/2010 50 Female 9/16/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Flushing Life Threatening 9/3/2010 50 Female 9/23/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 116 lb 9/27/2010 United States
Primary
Concomitant
Alopecia 3/1/2008 58 Female 9/29/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Other Serious 4/25/2005 42 Female 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/7/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 66 Female 126 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 10/16/2010 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious Female 10/18/2010 Other Health Professional Japan
Primary
Secondary
Oedema Peripheral Hospitalization 7/17/2010 70 Female 10/19/2010 Physician Italy
Primary
Concomitant
Dehydration Other Serious 72 Female 10/20/2010 Other Health Professional Japan
Primary
Secondary
Tachycardia Other Serious 9/15/2010 37 Female 119 lb 11/4/2010 Physician Australia
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 38 Female 11/9/2010 Other Health Professional United States
Primary
Concomitant
Dehydration Other Serious 72 Female 11/11/2010 Physician Japan
Primary
Secondary

Drug Data