Tamoxifen combined with Xeloda

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 12/1/2003 51 Female 1/5/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 9/14/2005 70 Female 165 lb 6/21/2006 Physician France
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 79 Female 6/4/2007 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 8/21/2007 72 Female 177 lb 8/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 12/1/2007 43 Female 1/11/2008 Consumer United States
Primary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 64 Female 147 lb 1/15/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2002 49 Female 176 lb 1/22/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 64 Female 147 lb 2/5/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 64 Female 147 lb 2/19/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 57 Female 146 lb 3/5/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 57 Female 157 lb 3/8/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 57 Female 157 lb 3/8/2008 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 3/12/2002 50 Female 140 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/13/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2001 47 Female 152 lb 3/17/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2001 57 Female 157 lb 3/18/2008 United States
Primary
Secondary
Concomitant
Erysipelas Hospitalization 4/8/2008 47 Female 254 lb 11/4/2008 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 65 Female 11/24/2008 Other Health Professional Japan
Primary
Secondary
Wrist Fracture Other Serious 1/1/2001 Female 106 lb 11/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 65 Female 11/26/2008 Other Health Professional Japan
Primary
Secondary
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 65 Female 12/2/2008 Other Health Professional Japan
Primary
Secondary
Tooth Disorder Other Serious 1/1/2001 Female 147 lb 12/9/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 12/19/2008 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/10/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2007 50 Female 6/11/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/14/2005 55 Female 127 lb 6/11/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/14/2010 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 6/15/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/15/2010 United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 2/13/2001 62 Female 134 lb 6/15/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/19/2003 81 Female 6/16/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/16/2003 68 Female 134 lb 6/18/2010 United States
Primary
Secondary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 6/22/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 56 Female 155 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/13/2001 62 Female 134 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2003 64 Female 6/29/2010 United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2003 60 Female 6/30/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/30/2010 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 1/1/2004 43 Female 235 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 7/13/2010 United States
Primary
Concomitant
Vomiting Other Serious 2/13/2001 62 Female 134 lb 7/14/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 7/15/2010 United States
Primary
Concomitant
Vomiting Other Serious 4/15/2003 55 Female 7/16/2010 United States
Primary
Concomitant
Tooth Fracture Other Serious 1/1/2001 45 Female 147 lb 7/19/2010 United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Other Serious 12/1/2005 43 Female 164 lb 7/19/2010 United States
Primary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 7/20/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 7/22/2010 United States
Primary
Concomitant
Wheelchair User Other Serious 8/1/1998 53 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/23/2010 United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 1/9/2004 69 Female 8/6/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Venous Occlusion Other Serious 1/1/2003 60 Female 121 lb 11/11/2010 United States
Primary
Concomitant
Vertebroplasty Other Serious 4/12/2005 51 Female 11/15/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 11/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Bearing Difficulty Other Serious 12/1/2005 43 Female 164 lb 11/24/2010 United States
Primary
Concomitant
Vulvovaginal Pruritus Other Serious 6/28/2002 45 Female 11/25/2010 United States
Primary
Concomitant
Wrist Fracture Other Serious 1/1/2001 54 Female 106 lb 11/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 4/15/2003 55 Female 1/19/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Other Serious 5/1/2002 58 Female 1/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thoracic Outlet Syndrome Death 1/1/2003 51 Female 154 lb 1/26/2011 Physician United States
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 6/1/2006 47 Female 1/26/2011 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious Female 1/28/2011 Lawyer United States
Primary
Concomitant
Vulval Abscess Hospitalization 1/1/2003 51 Female 154 lb 2/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Other Serious 4/12/2005 51 Female 2/25/2011 Other Health Professional United States
Primary
Concomitant
Gingival Swelling Other Serious 10/16/2003 68 Female 134 lb 3/11/2011 United States
Primary
Secondary
Concomitant
Fluid Retention Hospitalization 3/5/2002 51 Female 119 lb 3/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Follicle Stimulating Hormone Increased Hospitalization 3/5/2002 51 Female 119 lb 3/11/2011 United States
Primary
Secondary
Concomitant
Oropharyngeal Blistering Death 10/16/2003 68 Female 134 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 8/25/2002 68 Female 4/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Aspiration Hospitalization 11/29/2004 53 Female 4/27/2011 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 60 Female 121 lb 5/5/2011 Lawyer United States
Primary
Concomitant
Hypercholesterolaemia Other Serious 8/25/2002 68 Female 5/6/2011 Physician United States
Primary
Secondary
Concomitant
Disease Progression 1/4/2011 67 Female 5/2/2011 Other Health Professional United States
Primary
Concomitant
Joint Swelling Other Serious 9/22/2006 38 Female 165 lb 12/8/2011 Physician United States
Primary
Concomitant
Gait Disturbance Other Serious Female 123 lb 12/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious Female 12/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Confusional State Other Serious 5/31/2006 54 Female 148 lb 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Arthralgia Other Serious 1/1/2003 55 Female 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 10/3/2010 54 Female 123 lb 6/19/2012 Physician Poland
Primary
Secondary
Concomitant
Trismus Hospitalization 1/3/2005 59 Female 3/6/2013 Consumer Us
Primary
Concomitant
Uterine Fibrosis Other Serious Female 11/20/2012 Consumer Us
Primary
Concomitant
Pleural Effusion Other Serious 1/2008 62 Female 10/9/2012 Physician Pl
Primary
Secondary
Concomitant
Death Death Female 9/21/2012 Physician Us
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious Female 218 lb 9/26/2012 Physician Us
Primary
Secondary
Concomitant
Plantar Erythema Death Female 10/1/2012 Physician Us
Primary
Concomitant
Fall Other Serious Female 10/3/2012 Physician Us
Primary
Secondary
Concomitant
Paraplegia Other Serious Female 11/27/2012 Physician De
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 11/2003 Female 10/19/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious Female 11/1/2012 Physician Ca
Primary
Secondary
Rash Pruritic Other Serious Female 11/5/2012 Physician Au
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/2011 68 Female 119 lb 11/20/2012 Physician Be
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 10/22/2012 70 Female 12/26/2012 Physician Fr
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 10/22/2012 70 Female 12/28/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 10/22/2012 70 Female 1/2/2013 Other Health Professional Fr
Primary
Secondary
Concomitant
Off Label Use Death 2012 52 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Disease Progression Other Serious 1/2013 46 Female 109 lb 1/22/2013 Physician Be
Primary
Secondary
Treatment Failure Other Serious Female 5/9/2013 Physician Pl
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious Female 1/30/2013 Physician Pl
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 12/22/2009 69 Female 8/21/2013 Physician At
Primary
Secondary
Concomitant
Febrile Neutropenia Death 3/26/2012 Male Other Health Professional Us
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/26/2012 52 Male 3/13/2013 Consumer Us
Primary
Secondary
Concomitant
Metastasis Other Serious 6/2009 30 Female 4/18/2013 Physician Au
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 6/21/2013 Physician Dk
Primary
Secondary
Concomitant
Drug Intolerance Other Serious Female 4/24/2013 Physician Ca
Primary
Secondary
Vein Disorder Other Serious 2010 49 Female 145 lb 6/19/2013 Consumer Ca
Primary
Secondary
Concomitant
Skin Cancer Other Serious 4/2012 45 Female 5/23/2013 Consumer Dk
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 5/17/2013 Physician Dk
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 5/9/2013 Other Health Professional Dk
Primary
Secondary
Laryngitis 1/4/2011 67 Female 5/10/2013 Consumer Us
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Female 5/14/2013 Other Health Professional Ca
Primary
Secondary
Metastases To Bone Other Serious Female 5/23/2013 Physician Au
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 5/20/2013 Physician Dk
Primary
Secondary
Skin Cancer Other Serious Female 5/21/2013 Other Health Professional Dk
Primary
Secondary
Skin Exfoliation Other Serious 2004 70 Female 150 lb 5/24/2013 Consumer Br
Primary
Secondary
Concomitant
Neutropenia Required Intervention Female 5/17/2013 Other Health Professional Dk
Primary
Secondary
Metastatic Neoplasm Other Serious 6/2011 69 Female 5/30/2013 Consumer Dk
Primary
Secondary
Off Label Use Other Serious 69 Female 6/3/2013 Physician Dk
Primary
Secondary
Pleural Effusion Other Serious Female 6/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 6/3/2013 Physician Dk
Primary
Secondary
Metastatic Neoplasm Other Serious 69 Female 6/4/2013 Physician Dk
Primary
Secondary
Metastases To Liver Other Serious 69 Female 6/3/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Skin Cancer Other Serious 1/2013 45 Female 6/13/2013 Other Health Professional Dk
Primary
Secondary
Vomiting Other Serious 12/8/2003 46 Female 111 lb 1/16/2013 Consumer Us
Primary
Concomitant
Vision Blurred Other Serious 2003 49 Female 152 lb 8/28/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Secretion Other Serious 6/26/2003 64 Female 4/8/2013 Other Health Professional Us
Primary
Concomitant
Wheezing Hospitalization 2/5/1998 60 Female 167 lb 4/22/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Other Serious 12/12/2000 47 Female 8/30/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/2002 Female 147 lb 11/14/2012 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Death 11/29/2004 53 Female 7/17/2013 Consumer Us
Primary
Concomitant
Wound Other Serious 3/1/2002 50 Male 6/14/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2002 51 Female 188 lb 4/23/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/2006 48 Female 6/14/2013 Physician Us
Primary
Concomitant
Weight Decreased Death 3/2005 54 Female 265 lb 8/6/2013 Consumer Us
Primary
Concomitant
Vomiting Other Serious 4/15/2003 56 Female Other Health Professional Us
Primary
Concomitant
Walking Aid User Other Serious 1/9/2004 63 Female 7/12/2013 Consumer Us
Primary
Concomitant
Wound Death 6/25/2005 55 Female 8/8/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/26/2008 49 Female 129 lb 8/9/2013 Consumer Country Not Specified
Primary
Concomitant
Vomiting Hospitalization 5/2007 51 Female 8/8/2013 Consumer Us
Primary
Concomitant
Walking Aid User Other Serious 7/2004 75 Female 8/1/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Dehiscence Death 8/25/2002 68 Female 108 lb 8/28/2013 Consumer Us
Primary
Secondary
Concomitant
Vulvovaginal Pruritus Other Serious 2/9/2004 47 Female 5/8/2013 Consumer Us
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 2003 Female 155 lb 10/10/2012 Consumer Us
Primary
Secondary
Concomitant

Drug Data