Takepron combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Hospitalization 9/15/2005 57 Male 152 lb 2/10/2006 Physician Japan
Primary
Concomitant
Hypoglycaemic Encephalopathy Other Serious 2/5/2006 82 Female 83 lb 4/3/2006 Physician Japan
Primary
Secondary
Concomitant
Brain Stem Infarction Death 7/4/2008 Male 139 lb 12/29/2008 Physician Japan
Primary
Concomitant
Brain Stem Infarction Death 9/19/2008 Male 139 lb 2/25/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/11/2008 Female 77 lb 4/9/2009 Physician Japan
Primary
Secondary
Concomitant
Generalised Erythema Other Serious 2/24/2009 4/30/2009 Pharmacist Japan
Primary
Concomitant
Generalised Erythema Other Serious 2/24/2009 71 5/22/2009 Japan
Primary
Concomitant
Movement Disorder Hospitalization 5/14/2009 83 6/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 12/1/2008 68 6/19/2009 Other Health Professional Japan
Primary
Concomitant
Death Death 48 6/24/2009 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/15/2008 68 6/26/2009 Other Health Professional Japan
Primary
Concomitant
Hypoglycaemia Other Serious 12/15/2008 76 Male 161 lb 7/2/2009 Physician Japan
Primary
Concomitant
Rhinitis Other Serious 11/1/2007 Male 143 lb 7/2/2009 Physician Japan
Primary
Concomitant
Pneumonia Death 5/1/2009 48 7/1/2009 Physician Japan
Primary
Concomitant
Movement Disorder Hospitalization 5/13/2009 83 7/10/2009 Other Health Professional Japan
Primary
Concomitant
Ileus Hospitalization 7/15/2009 75 7/31/2009 Other Health Professional Japan
Primary
Concomitant
Generalised Erythema Other Serious 2/24/2009 71 8/3/2009 Japan
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 7/15/2009 69 9/17/2009 Other Health Professional Japan
Primary
Concomitant
Liver Disorder Hospitalization 8/13/2009 57 9/22/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2009 68 Female 106 lb 9/24/2009 Physician Japan
Primary
Concomitant
Pneumatosis Intestinalis Hospitalization 7/15/2009 69 10/6/2009 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/13/2009 57 10/9/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 11/27/2009 78 Female 106 lb 12/31/2009 Japan
Primary
Secondary
Concomitant
Weight Decreased 6/16/2009 Female 1/8/2010 Physician Japan
Primary
Concomitant
Tremor Hospitalization 10/2/2009 Female 2/15/2010 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 1/30/2010 Male 126 lb 3/1/2010 Physician Japan
Primary
Concomitant
Hypothyroidism Other Serious 12/4/2009 0 Female 5 lb 3/25/2010 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Hospitalization 8/4/2009 61 Female 134 lb 5/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/18/2008 76 Male 6/3/2010 Physician Japan
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 5/8/2010 76 Female 6/18/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Arrest Death 11/10/2007 86 Female 6/18/2010 Other Health Professional Japan
Primary
Concomitant
Muscular Weakness Hospitalization 4/5/2010 66 Male 6/25/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 76 Male 112 lb 7/5/2010 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Hospitalization 6/26/2009 80 Male 97 lb 7/7/2010 Physician Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 1/20/2009 75 Female 119 lb 8/6/2010 Other Health Professional Japan
Primary
Concomitant
Mouth Ulceration Other Serious 5/8/2010 76 Female 8/6/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 8/16/2010 Japan
Primary
Concomitant
Pulmonary Oedema Hospitalization 7/21/2010 82 Female 8/11/2010 Physician Japan
Primary
Concomitant
Death Death 2/16/2009 56 Male 118 lb 8/26/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 8/2/2010 62 Male 130 lb 9/7/2010 Physician Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 1/20/2009 75 Female 119 lb 9/10/2010 Other Health Professional Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 9/13/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 9/23/2010 Pharmacist Japan
Primary
Concomitant
Respiratory Failure Other Serious 8/31/2010 79 Male 137 lb 10/19/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Death 79 Male 11/4/2010 Physician Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 37 Male 146 lb 11/9/2010 Physician Japan
Primary
Concomitant
In-stent Coronary Artery Restenosis Hospitalization 37 Male 146 lb 11/10/2010 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Death 2/16/2009 56 Male 118 lb 11/11/2010 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 8/6/2010 33 Male 11/15/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Pneumonia Bacterial Hospitalization 9/27/2010 80 Male 154 lb 11/18/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization Male 11/19/2010 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 9/6/2010 79 Male 137 lb 12/2/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Life Threatening 11/25/2010 63 Male 157 lb 12/22/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 12/1/2010 66 Female 119 lb 1/5/2011 Physician Japan
Primary
Concomitant
Weight Decreased Death 6/9/2009 73 Female 1/11/2011 Physician Japan
Primary
Concomitant
Death Death 7/29/2010 69 Female 1/14/2011 Physician Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/12/2010 75 Male 1/14/2011 Physician Japan
Primary
Concomitant
Cardiomegaly Other Serious 12/3/2010 72 Male 1/14/2011 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Death 4/1/2010 75 Female 112 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/21/2010 73 Female 86 lb 1/31/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/14/2010 73 Male 2/1/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 7/29/2010 69 Female 2/4/2011 Physician Japan
Primary
Concomitant
Hyponatraemia Other Serious 12/19/2010 85 Male 140 lb 2/8/2011 Pharmacist Japan
Primary
Concomitant
Abdominal Pain Hospitalization 1/28/2011 78 Male 132 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Hospitalization 1/21/2011 61 Female 132 lb 2/10/2011 Physician Japan
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 1/28/2011 78 Male 132 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 2/11/2011 75 Female 2/18/2011 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 7/24/2010 77 Male 2/22/2011 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 1/28/2011 78 Male 132 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 11/1/2010 71 Male 128 lb 2/21/2011 Physician Japan
Primary
Concomitant
Altered State Of Consciousness Other Serious 12/7/2010 79 Male 95 lb 3/7/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Asphyxia Death 2/10/2011 75 Male 2/23/2011 Other Health Professional Japan
Primary
Concomitant
Asphyxia Death 2/10/2011 75 Male 2/23/2011 Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 2/11/2011 75 Female 3/10/2011 Physician Japan
Primary
Concomitant
Alopecia Hospitalization 8/2/2010 40 Male 190 lb 3/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/28/2010 77 Female 3/15/2011 Physician Japan
Primary
Secondary
Concomitant
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 3/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Clostridium Test Positive Death 12/1/2010 83 Female 86 lb 3/15/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 3/1/2011 82 Female 3/17/2011 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2011 78 Male 132 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/1/2011 82 Female 3/29/2011 Pharmacist Japan
Primary
Concomitant
Overdose Hospitalization 2/14/2011 73 Male 3/31/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Gait Disturbance Hospitalization 10/15/2010 62 Male 110 lb 4/12/2011 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Hospitalization 8/31/2010 40 Male 190 lb 4/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cholangitis Other Serious 1/28/2011 78 Male 132 lb 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Life Threatening 3/6/2011 82 Female 93 lb 4/19/2011 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/31/2011 69 Female 4/28/2011 Pharmacist Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 2/5/2010 71 Male 5/5/2011 Physician Japan
Primary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/21/2010 73 Female 86 lb 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Other Serious 9/21/2010 73 Female 86 lb 3/13/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/25/2010 62 Female 135 lb 12/21/2012 Physician Jp
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 6/18/2011 75 Male 117 lb 8/29/2012 Physician Jp
Primary
Concomitant
Pruritus Death 9/21/2011 88 Female 106 lb 4/12/2013 Physician Jp
Primary
Secondary
Concomitant
Rash Disability 6/27/2011 72 Female 11/16/2012 Physician Jp
Primary
Concomitant
Metastases To Bone Hospitalization 2/9/2012 75 Female 88 lb 9/11/2012 Physician Jp
Primary
Concomitant
Thrombocytopenia Death 4/6/2011 80 Male 11/12/2012 Physician Jp
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 7/7/2012 76 Male 101 lb 11/4/2012 Physician Jp
Primary
Secondary
Concomitant
Death Death 7/19/2012 72 Female 85 lb 2/7/2013 Physician Jp
Primary
Concomitant
Subclavian Artery Stenosis Disability 11/26/2008 69 Female 93 lb 3/8/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Life Threatening 12/25/2011 84 Female 88 lb 12/5/2012 Physician Jp
Primary
Concomitant
Sepsis Hospitalization 5/1/2012 79 Female 88 lb 9/18/2012 Physician Jp
Primary
Concomitant
Venous Thrombosis Limb Other Serious 3/10/2009 68 Female 110 lb 1/2/2013 Physician Jp
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 1/13/2012 68 Female 123 lb 9/14/2012 Other Health Professional Jp
Primary
Concomitant
Myalgia Hospitalization 7/28/2012 73 Male 102 lb 8/31/2012 Pharmacist Jp
Primary
Concomitant
Ileus Paralytic Hospitalization 6/7/2012 81 Male 8/30/2012 Other Health Professional Jp
Primary
Concomitant
Septic Shock Hospitalization 7/15/2012 50 Female 105 lb 9/4/2012 Physician Jp
Primary
Secondary
Concomitant
Febrile Neutropenia Death 7/15/2012 68 Male 108 lb 10/22/2012 Physician Jp
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/18/2012 9/10/2012 Pharmacist Jp
Primary
Concomitant
Hypoglycaemia Life Threatening 8/24/2012 83 Male 11/12/2012 Consumer Jp
Primary
Secondary
Concomitant
Influenza Other Serious 11/19/2008 44 Male 1/31/2013 Physician Jp
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 3/23/2012 86 Male 110 lb 4/15/2013 Other Health Professional Jp
Primary
Concomitant
International Normalised Ratio Increased 9/18/2012 89 Female 11/25/2012 Physician Jp
Primary
Secondary
Concomitant
Interacting
Wrong Drug Administered Other Serious 10/1/2011 81 Male 12/21/2012 Physician Jp
Primary
Secondary
Concomitant
Anaemia Other Serious 8/14/2012 73 Female 88 lb 10/12/2012 Physician Jp
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious Male 12/19/2012 Physician Jp
Primary
Concomitant
Pancytopenia Hospitalization 8/31/2012 90 Male 148 lb 11/10/2012 Physician Jp
Primary
Concomitant
Pulmonary Hypertension Other Serious 5/14/2012 79 Female 10/31/2012 Physician Jp
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/28/2011 78 Male 132 lb 10/31/2012 Physician Jp
Primary
Secondary
Concomitant
Eosinophil Count Increased Other Serious 4/13/2012 78 Male 143 lb 3/22/2013 Physician Jp
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/13/2012 60 Male 152 lb 11/5/2012 Physician Jp
Primary
Concomitant
Melaena Other Serious 6/19/2010 62 Male 134 lb 11/8/2012 Physician Jp
Primary
Concomitant
Thirst Other Serious 8/11/2012 80 Female 125 lb 5/17/2013 Physician Jp
Primary
Concomitant
Interstitial Lung Disease Hospitalization 11/2/2012 74 Male 12/18/2012 Pharmacist Jp
Primary
Secondary
Skin Ulcer Hospitalization 10/28/2012 75 Male 119 lb 12/27/2012 Physician Jp
Primary
Secondary
Concomitant
Pulmonary Embolism Death 11/28/2012 72 Male 137 lb 5/8/2013 Physician Jp
Primary
Concomitant
Thalamus Haemorrhage Hospitalization 2/2012 Female 77 lb 1/24/2013 Physician Jp
Primary
Secondary
Concomitant
Deep Vein Thrombosis Death 10/15/2012 58 Male 2/13/2013 Physician Jp
Primary
Secondary
Concomitant
Liver Disorder Other Serious 12/27/2012 52 Male 4/9/2013 Pharmacist Jp
Primary
Concomitant
Hypoglycaemia Hospitalization 8/7/2012 Male 1/23/2013 Pharmacist Jp
Primary
Concomitant
Oedema Peripheral Hospitalization 8/1/2012 Female 96 lb 3/5/2013 Physician Jp
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10/15/2012 Male 97 lb 2/15/2013 Physician Jp
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/24/2013 56 Male 130 lb 2/25/2013 Other Health Professional Jp
Primary
Concomitant
Large Intestinal Ulcer Haemorrhage Other Serious 1/2013 62 Female 3/25/2013 Consumer Jp
Primary
Secondary
Concomitant
Potentiating Drug Interaction Other Serious 12/18/2012 81 Male 2/14/2013 Physician Jp
Primary
Concomitant
Interacting
Pancytopenia Other Serious 2/1/2013 85 Female 106 lb 4/1/2013 Pharmacist Jp
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 11/25/2012 85 Male 108 lb 2/9/2013 Physician Jp
Primary
Concomitant
Respiratory Failure Death 10/6/2012 80 Male 3/11/2013 Physician Jp
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 8/1/2012 82 Male 128 lb 3/21/2013 Physician Jp
Primary
Concomitant
Cold Sweat Other Serious 2/22/2011 52 Male 170 lb 3/26/2013 Physician Jp
Primary
Concomitant
Thirst Death 12/20/2012 61 Male 146 lb 6/7/2013 Physician Jp
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 3/29/2012 70 Male 185 lb 11/2/2012 Physician Jp
Primary
Concomitant
Death Death 46 Male 139 lb 5/29/2013 Physician Jp
Primary
Concomitant
Epistaxis Death 12/2012 76 Female 106 lb 6/10/2013 Physician Jp
Primary
Concomitant
Acute Myocardial Infarction Death 5/19/2013 88 Male 108 lb 6/11/2013 Physician Jp
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2011 78 Male 132 lb 10/31/2012 Physician Jp
Primary
Secondary
Concomitant
Large Intestine Polyp Hospitalization 3/9/2010 61 Male 168 lb 12/4/2012 Physician Jp
Primary
Concomitant

Drug Data