Sunitinib Malate combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 6/23/2006 62 Male 7/5/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 10/18/2006 57 Male 220 lb 12/6/2006 United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Disability 4/10/2006 74 Male 12/28/2006 Italy
Primary
Concomitant
Weight Decreased Hospitalization 5/9/2006 Female 249 lb 4/26/2007 United States
Primary
Concomitant
Failure To Thrive Hospitalization 5/9/2006 Female 249 lb 5/11/2007 United States
Primary
Concomitant
Osteonecrosis Other Serious 58 Male 8/20/2007 Physician Philippines
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Male 8/20/2007 Physician Philippines
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 58 Male 8/20/2007 Physician Philippines
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/11/2007 64 Male 3/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 8/1/2007 Male 4/26/2008 Physician Belgium
Primary
Concomitant
Oral Intake Reduced Hospitalization 6/13/2007 Male 5/29/2008 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 7/9/2008 Male 9/23/2008 Germany
Primary
Concomitant
Abscess Jaw Hospitalization 8/23/2008 Female 115 lb 9/24/2008 Physician United States
Primary
Concomitant
Tooth Extraction Hospitalization 8/23/2008 Female 115 lb 11/7/2008 Physician United States
Primary
Concomitant
Cholecystitis Other Serious 4/10/2008 43 Female 172 lb 11/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 9/11/2007 Male 11/19/2008 Other Health Professional United States
Primary
Concomitant
Pelvic Fluid Collection Other Serious 5/1/2008 Female 218 lb 11/21/2008 Physician United States
Primary
Concomitant
Tooth Extraction Hospitalization 8/23/2008 Female 115 lb 12/10/2008 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 7/15/2008 Female 12/12/2008 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 12/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 5/11/2006 1/9/2009 Physician France
Primary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 1/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 1/23/2009 Physician United States
Primary
Secondary
Concomitant
Anal Fistula Hospitalization 1/15/2009 Female 146 lb 1/30/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/5/2009 Male 236 lb 1/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 2/6/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/14/2008 2/11/2009 Physician Japan
Primary
Concomitant
Anal Abscess Hospitalization 1/15/2009 Female 143 lb 2/11/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/20/2009 Male 236 lb 2/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sensation Of Foreign Body Other Serious Male 2/16/2009 Physician United Kingdom
Primary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 2/17/2009 United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 4/10/2008 Female 172 lb 2/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 119 lb 3/2/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 1/30/2008 3/6/2009 Other Health Professional France
Primary
Secondary
Pain Hospitalization 9/5/2008 Female 406 lb 3/10/2009 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/20/2009 Male 336 lb 3/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 3/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/20/2009 Male 237 lb 3/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Due To A General Medical Condition Hospitalization 6/20/2008 3/20/2009 Physician Germany
Primary
Concomitant
Cholecystitis Other Serious 4/10/2008 Female 172 lb 3/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 4/2/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 1/28/2009 4/6/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 4/7/2009 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/20/2009 Male 237 lb 4/20/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Tubulointerstitial Nephritis Other Serious 1/20/2009 Male 237 lb 4/20/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Pyrexia Other Serious 11/14/2008 4/27/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/4/2009 60 5/8/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/17/2009 Female 181 lb 5/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/13/2009 60 5/21/2009 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 1/20/2006 Female 123 lb 5/22/2009 United States
Primary
Concomitant
Atrioventricular Block Other Serious 5/6/2009 52 5/22/2009 Physician France
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/17/2009 Female 181 lb 5/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/4/2009 60 5/29/2009 Physician Japan
Primary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 5/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/26/2009 26 6/5/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/17/2009 Female 181 lb 6/9/2009 United States
Primary
Secondary
Concomitant
Atrioventricular Block Other Serious 5/6/2009 52 6/17/2009 Physician France
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Death 4/13/2009 60 6/24/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 1/28/2009 62 6/30/2009 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/16/2009 Female 181 lb 7/10/2009 United States
Primary
Secondary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 7/20/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/4/2009 60 7/22/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Disability 9/1/2008 56 7/28/2009 Physician Italy
Primary
Secondary
Renal Disorder Other Serious 3/9/2009 59 7/29/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 2/27/2009 59 8/4/2009 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/16/2009 Female 181 lb 8/4/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2009 54 8/14/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/14/2008 53 8/19/2009 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/16/2009 Female 181 lb 8/20/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2009 54 8/28/2009 Physician Japan
Primary
Concomitant
Mouth Ulceration Hospitalization 6/13/2007 Male 9/7/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 133 lb 9/14/2009 Other Health Professional United States
Primary
Concomitant
Abscess Limb Hospitalization 3/17/2009 10/2/2009 Physician Germany
Primary
Concomitant
Pain Hospitalization 9/5/2008 Female 406 lb 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Pain Life Threatening 9/5/2008 Female 406 lb 10/12/2009 Physician United States
Primary
Secondary
Concomitant
Abscess Limb Hospitalization 3/17/2009 10/14/2009 Physician Germany
Primary
Concomitant
Pneumonia Bacterial Hospitalization 8/24/2009 79 10/26/2009 Physician Japan
Primary
Concomitant
Mouth Ulceration Hospitalization 6/13/2007 Male 11/11/2009 Physician United States
Primary
Concomitant
Osteonecrosis Hospitalization 10/21/2009 Male 194 lb 11/13/2009 Physician United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 8/6/2009 79 Male 150 lb 11/17/2009 Physician Japan
Primary
Concomitant
Pain Life Threatening 9/5/2008 Female 406 lb 11/23/2009 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 5/31/2008 Male 254 lb 12/15/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 2/22/2008 Male 179 lb 12/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Other Serious 11/24/2009 Male 126 lb 12/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 11/13/2009 51 Female 12/30/2009 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 3/9/2009 59 Male 111 lb 2/15/2010 Physician Japan
Primary
Concomitant
Renal Disorder 3/9/2009 59 Male 111 lb 2/16/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2009 54 Male 167 lb 3/5/2010 Physician Japan
Primary
Concomitant
Perirectal Abscess Hospitalization 5/23/2008 Male 254 lb 3/9/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2009 54 Male 167 lb 3/15/2010 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/26/2009 26 Female 127 lb 3/24/2010 Physician Japan
Primary
Concomitant
Pelvic Fluid Collection Other Serious 5/1/2008 Female 99 lb 3/24/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/15/2009 54 Male 167 lb 3/26/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/22/2008 Male 179 lb 3/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/10/2009 57 Female 93 lb 3/31/2010 Physician Japan
Primary
Concomitant
Psychotic Disorder Due To A General Medical Condition Hospitalization 6/20/2008 68 Male 126 lb 4/1/2010 Physician Germany
Primary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 4/23/2010 Japan
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 1/20/2009 71 Male 236 lb 4/23/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Oral Fungal Infection Hospitalization 3/23/2010 65 Male 5/3/2010 Other Health Professional Denmark
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 4/21/2010 76 Male 187 lb 5/3/2010 Physician Germany
Primary
Secondary
Concomitant
Toothache Other Serious 55 Male 5/4/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious Male 5/5/2010 Physician Italy
Primary
Concomitant
Lung Abscess Hospitalization 1/21/2010 72 Male 174 lb 5/7/2010 Physician Japan
Primary
Concomitant
Perirectal Abscess Hospitalization 5/23/2008 74 Male 254 lb 5/12/2010 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2009 60 Male 5/17/2010 Other Health Professional Italy
Primary
Concomitant
Nervous System Disorder Other Serious 4/21/2010 76 Male 187 lb 5/17/2010 Physician Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 8/10/2009 57 Female 93 lb 5/17/2010 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 9/11/2007 64 Male 5/19/2010 Other Health Professional United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 67 Male 5/24/2010 Physician Italy
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2009 60 Male 5/27/2010 Other Health Professional Italy
Primary
Concomitant
Pleural Effusion Hospitalization 2/16/2009 60 Female 181 lb 5/28/2010 United States
Primary
Secondary
Concomitant
Cholecystitis Other Serious 4/10/2008 43 Female 172 lb 5/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 4/21/2010 76 Male 187 lb 6/7/2010 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/27/2010 66 Male 6/11/2010 Other Health Professional Italy
Primary
Concomitant
Pleural Effusion Other Serious 8/10/2009 57 Female 93 lb 6/11/2010 Japan
Primary
Concomitant
Cerebrovascular Accident Hospitalization 5/4/2010 76 Male 169 lb 6/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 4/21/2010 76 Male 187 lb 6/17/2010 Physician Germany
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 4/21/2010 76 Male 187 lb 6/29/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/22/2008 56 Male 154 lb 6/28/2010 Physician Japan
Primary
Concomitant
Lung Abscess Hospitalization 1/21/2010 72 Male 174 lb 6/30/2010 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 7/1/2010 Physician Japan
Primary
Secondary
Concomitant
Anaemia Hospitalization 2/17/2010 53 Male 201 lb 7/1/2010 Physician Belgium
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 4/21/2010 76 Male 187 lb 7/9/2010 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/27/2010 66 Male 7/19/2010 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2009 71 Male 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 4/5/2010 68 Male 132 lb 8/3/2010 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/22/2008 56 Male 154 lb 8/3/2010 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/26/2009 26 Female 127 lb 8/6/2010 Physician Japan
Primary
Concomitant
Performance Status Decreased Hospitalization 6/18/2010 69 Male 192 lb 8/9/2010 Physician Germany
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 3/11/2009 61 Male 8/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 1/26/2009 26 Female 127 lb 8/24/2010 Physician Japan
Primary
Concomitant
Performance Status Decreased Hospitalization 6/18/2010 69 Male 192 lb 8/25/2010 Physician Germany
Primary
Secondary
Concomitant
Cellulitis Hospitalization 8/7/2010 64 Male 205 lb 9/17/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2009 71 Male 10/4/2010 Physician United States
Primary
Secondary
Concomitant
Oesophagitis Hospitalization 3/25/2009 72 Male 159 lb 10/18/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 6/2/2010 45 Male 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 9/22/2009 81 Male 146 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/21/2010 78 Male 10/26/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 9/22/2009 81 Male 146 lb 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/8/2010 Other Health Professional Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Hospitalization 1/30/2008 64 Male 11/12/2010 Other Health Professional France
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Mouth Ulceration Hospitalization 6/13/2007 58 Male 12/7/2010 Physician United States
Primary
Concomitant
Pyrexia Other Serious 8/21/2010 78 Male 12/8/2010 Physician Japan
Primary
Concomitant
Tooth Loss Disability Male 12/13/2010 Physician United Kingdom
Primary
Concomitant
Cerebral Ischaemia Hospitalization 10/28/2009 69 12/22/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Confusional State Hospitalization 9/22/2009 81 Male 140 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Disability Male 12/22/2010 Physician United Kingdom
Primary
Concomitant

Drug Data