Stavudine combined with Tenofovir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Po2 Increased Hospitalization 3/27/2004 60 Male 1/5/2006
Primary
Secondary
Renal Tubular Necrosis Other Serious 51 Male 1/11/2006 Other Health Professional Germany
Primary
Secondary
Renal Tubular Necrosis Hospitalization 53 Male 1/11/2006 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Drug Withdrawal Syndrome Hospitalization 51 Male 1/19/2006 Australia
Primary
Secondary
Concomitant
Interacting
Staphylococcal Infection Other Serious 7/9/2004 Male 1/23/2006 Japan
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 51 Male 1/27/2006 Australia
Primary
Secondary
Concomitant
Interacting
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Lactic Acidosis Hospitalization 11/25/2005 41 Male 148 lb 2/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2004 44 Male 2/24/2006 United States
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/1/2003 39 Male 3/7/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2003 39 Male 3/13/2006 Physician France
Primary
Secondary
Concomitant
Lipoma Other Serious 5/23/2005 33 Male 4/6/2006 Physician Spain
Primary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 6/30/2005 Male 215 lb 5/10/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/1998 Male 139 lb 5/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Splenomegaly Other Serious 10/3/2003 Male 5/17/2006 Other Health Professional United States
Primary
Concomitant
Drug Level Decreased Other Serious 65 Male 5/18/2006 Other Health Professional United States
Primary
Concomitant
Interacting
Death Death 6/30/2005 Male 5/18/2006 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Disability 11/10/1999 Male 6/7/2006 Physician Japan
Primary
Secondary
Proteinuria Hospitalization 4/11/2006 Male 134 lb 6/12/2006
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 38 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 37 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 27 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 59 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Urine Uric Acid Decreased Hospitalization 1/30/2006 37 Male 7/7/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 51 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Premature Baby Other Serious Female 7/14/2006 Germany
Primary
Secondary
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 1/1/2006 33 Male 7/24/2006 Physician Italy
Primary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/9/2004 53 Male 7/28/2006 Canada
Primary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/9/2004 Male 8/21/2006 Physician Japan
Primary
Secondary
Concomitant
Premature Baby Other Serious Female 8/21/2006 Germany
Primary
Secondary
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Pancreatitis Other Serious 7/1/2003 41 Male 8/21/2006 Consumer United States
Primary
Secondary
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 8/24/2006 Physician United Kingdom
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 60 Male 8/30/2006 Other Health Professional France
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Normochromic Normocytic Anaemia Hospitalization 12/22/2004 Male 134 lb 9/1/2006
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 9/7/2006 Physician Japan
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 6/21/2005 Male 9/7/2006 Physician Japan
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Disability 11/10/1999 Male 9/14/2006 Physician Japan
Primary
Secondary
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/23/2006 Male 154 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 6/21/2005 Male 9/25/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 9/28/2006 Physician United Kingdom
Primary
Concomitant
Lymphoma Hospitalization 2/14/2005 Male 9/28/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2006 Male 143 lb 9/29/2006 Physician Austria
Primary
Secondary
Concomitant
Pneumonitis Other Serious 9/1/1997 46 Male 10/3/2006
Primary
Secondary
Death Death 4/19/2004 Male 10/10/2006 Italy
Primary
Concomitant
Pleural Effusion Death 34 Female 10/12/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 10/12/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 1/1/2005 33 Male 10/16/2006 Physician Italy
Primary
Concomitant
Vomiting Hospitalization 9/19/2006 Male 143 lb 10/16/2006 Physician Austria
Primary
Secondary
Concomitant
Pleural Effusion Death 34 Female 10/11/2006 South Africa
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2006 Male 143 lb 11/3/2006 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/6/2005 Male 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 4/28/2005 Male 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Disorder Other Serious 11/9/2006 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/19/2006 43 Male 143 lb 11/17/2006 Physician Austria
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 4/28/2005 Male 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2006 43 Male 143 lb 11/30/2006 Physician Austria
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2001 42 Male 130 lb 12/1/2006 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 38 Female 121 lb 12/8/2006 Other Health Professional Spain
Primary
Concomitant
Lymphoma Hospitalization 2/14/2005 Male 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2003 Male 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/6/2005 Male 1/18/2007 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Lymphoma Hospitalization 2/14/2005 Male 2/8/2007 Physician Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 56 Male 161 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 56 Male 126 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 30 Female 97 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 4/13/2007 Physician Canada
Primary
Secondary
Concomitant
Dizziness Hospitalization 5/10/2006 Male 110 lb 4/18/2007 Physician Argentina
Primary
Secondary
Concomitant
Vertical Infection Transmission Other Serious 5/3/2007
Primary
Secondary
Cytomegalovirus Myocarditis Other Serious 1/23/2007 Female 119 lb 5/4/2007 Physician Italy
Primary
Secondary
Concomitant
Congenital Anomaly Congenital Anomaly 11/8/2006 Male 5 lb 5/7/2007 Other Health Professional United States
Primary
Secondary
Hypertriglyceridaemia Other Serious 8/1/2001 39 Male 5/1/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Hospitalization 4/15/2005 Male 185 lb 5/17/2007 United States
Primary
Concomitant
Thrombosis In Device Hospitalization 61 Male 5/22/2007 Other Health Professional Austria
Primary
Secondary
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombosis In Device Hospitalization 61 Male 5/24/2007 Other Health Professional Austria
Primary
Secondary
Weight Decreased Life Threatening 2/2/2007 41 Female 5/25/2007 Physician Zimbabwe
Primary
Secondary
Concomitant
Eyelid Ptosis Hospitalization 12/1/2006 74 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 53 Male 5/17/2007 France
Primary
Secondary
Concomitant
Lymphoma Life Threatening 2/7/2005 61 Male 6/1/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/23/2007 Female 119 lb 6/7/2007 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 11/19/1997 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 4/1/2000 32 Female 97 lb 6/25/2007 Physician Belgium
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 6/2/2006 Male 187 lb 7/6/2007 Physician
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Disability 11/10/1999 Male 7/13/2007 Physician Japan
Primary
Secondary
Splenomegaly Hospitalization 6/1/2006 Male 7/13/2007 Physician Spain
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 6/2/2006 Male 187 lb 7/20/2007 Physician
Primary
Concomitant
Sarcoma Hospitalization 5/20/2003 Male 7/24/2007 United States
Primary
Concomitant
Splenomegaly Hospitalization 6/1/2006 Male 7/27/2007 Physician Spain
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/19/2007 Other Health Professional Italy
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/22/2007 Other Health Professional Italy
Primary
Secondary
Demyelination Hospitalization 9/3/2007 Female 117 lb 10/29/2007 Spain
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/4/2005 Male 12/27/2007 Physician Japan
Primary
Secondary
Concomitant
Gun Shot Wound Death 6/30/2005 Male 2/27/2008 United States
Primary
Concomitant
Diffuse Panbronchiolitis Hospitalization 6/20/2005 Male 3/5/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/23/2007 Female 119 lb 4/1/2008 Physician Italy
Primary
Secondary
Concomitant
Waist Circumference Increased Hospitalization 50 Male 4/1/2008 Consumer Italy
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 10/22/2007 35 Male 4/7/2008 Physician Zimbabwe
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/9/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/28/2008 Male 118 lb 4/11/2008
Primary
Concomitant
Liver Disorder Death 33 Male 119 lb 5/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Other Serious 43 Male 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/4/2005 Male 5/22/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 5/22/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Liver Disorder Death 33 Male 119 lb 6/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2000 Male 6/3/2008
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/19/2008 28 Female 6/5/2008 Physician Zimbabwe
Primary
Secondary
Concomitant

Drug Data