Stavudine combined with Tenofovir Disoproxil Fumarate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Skeletal Injury Other Serious 2/14/2004 Male 79 lb 3/29/2006 United States
Primary
Concomitant
Pain In Extremity Other Serious 2/14/2004 12 Male 79 lb 3/29/2006 Physician United States
Primary
Concomitant
Urine Output Decreased Life Threatening 9/29/2005 Female 6/19/2006 United Kingdom
Primary
Concomitant
Swelling Face Life Threatening 9/29/2005 Female 7/10/2006 United Kingdom
Primary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 55 Male 3/14/2007 Other Health Professional United States
Primary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Spinal Fracture Other Serious 11/2/2006 Male 115 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/10/2006 Male 110 lb 3/26/2007 Physician Argentina
Primary
Secondary
Concomitant
Dizziness Hospitalization 5/10/2006 Male 110 lb 3/30/2007 Physician Argentina
Primary
Secondary
Concomitant
Nephropathy Toxic Death 30 Female 97 lb 5/1/2007 United States
Primary
Concomitant
Interacting
Stillbirth Other Serious 12/25/2005 38 Female 5/14/2007 Other Health Professional Uganda
Primary
Secondary
Abortion Spontaneous Other Serious 9/24/2006 38 Female 5/14/2007 Other Health Professional Uganda
Primary
Secondary
Stillbirth Other Serious 7/14/2006 32 Female 5/15/2007 Other Health Professional Uganda
Primary
Secondary
Hepatic Cirrhosis Hospitalization 4/25/2005 39 Male 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 32 Female 97 lb 6/15/2007 Belgium
Primary
Secondary
Concomitant
Urinary Sediment Abnormal Hospitalization 7/27/2000 Male 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2003 Male 8/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 2/7/2005 61 Male 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
Vaginal Haemorrhage Life Threatening 8/7/2007 Female 9/21/2007 Ireland
Primary
Concomitant
Treatment Failure Other Serious 34 Male 9/18/2007 Physician Brazil
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/6/2005 Male 9/28/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/7/2007 Female 10/12/2007 Brazil
Primary
Concomitant
Pancytopenia Hospitalization 10/22/2007 35 Male 11/1/2007 Physician Zimbabwe
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 11/1/2007 Physician United States
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Demyelination Hospitalization 9/3/2007 Female 117 lb 11/7/2007 Spain
Primary
Concomitant
Muscular Weakness Other Serious 25 Female 11/12/2007 Other Health Professional Brazil
Primary
Secondary
Pancytopenia Hospitalization 10/22/2007 35 Male 11/15/2007 Physician Zimbabwe
Primary
Secondary
Concomitant
Vaginal Haemorrhage Life Threatening 8/7/2007 Female 150 lb 11/16/2007 Brazil
Primary
Concomitant
Hypertriglyceridaemia Other Serious Male 11/16/2007 Other Health Professional Canada
Primary
Interacting
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 11/22/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 11/27/2007 Other Health Professional United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 39 Male 11/30/2007 Other Health Professional Canada
Primary
Concomitant
Interacting
Premature Rupture Of Membranes Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Interstitial Lung Disease Hospitalization 12 Female 12/10/2007
Primary
Secondary
Gastroenteritis Hospitalization 12/4/2007 38 Male 139 lb 12/13/2007 Zimbabwe
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Immune Reconstitution Syndrome Hospitalization 5/1/2007 53 Male 12/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/13/2007 Other Health Professional United States
Primary
Concomitant
Enterocolitis Haemorrhagic Hospitalization 5/26/2004 Male 12/14/2007 Physician Japan
Primary
Concomitant
Gastroenteritis Hospitalization 12/3/2007 38 Male 139 lb 12/17/2007 Zimbabwe
Primary
Secondary
Concomitant
Weight Increased Hospitalization 54 Male 12/28/2007 Japan
Primary
Secondary
Liver Disorder Death 33 Male 119 lb 1/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Homicide Death 6/30/2005 Male 215 lb 2/1/2008 United States
Primary
Concomitant
Diffuse Panbronchiolitis Hospitalization 6/20/2005 Male 2/4/2008 Physician Japan
Primary
Secondary
Concomitant
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 6/12/2005 Male 194 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Overdose Other Serious 10/9/2007 Male 4/14/2008 South Africa
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/24/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious Unknown 4/22/2008 Consumer United States
Primary
Secondary
Nausea Other Serious Unknown 4/22/2008 Consumer United States
Primary
Secondary
Renal Failure Acute Other Serious 4/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Life Threatening 3/28/2008 Male 118 lb 4/30/2008
Primary
Concomitant
Hepatic Steatosis Other Serious 46 Male 4/29/2008 United States
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 4/17/2008 Male 82 lb 5/8/2008 United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 4/17/2008 Male 5/15/2008 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Chronic Death Unknown 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death Unknown 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Death Unknown 7/31/2008 United Kingdom
Primary
Secondary
Concomitant
Microsporidia Infection Other Serious 36 Male 10/21/2008 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 35 Male 12/10/2008 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 12/23/2008 Other Health Professional Spain
Primary
Secondary
Lung Neoplasm Malignant Death 12/23/2008 Other Health Professional Spain
Primary
Secondary
Myocardial Infarction Death 12/23/2008 Other Health Professional Spain
Primary
Secondary
Stress Hospitalization 41 Male 2/4/2009 Consumer United States
Primary
Secondary
Stress Hospitalization 41 Male 2/12/2009 Consumer United States
Primary
Secondary
Hepatic Cirrhosis Hospitalization 4/25/2005 39 Male 3/10/2009 United States
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 4/25/2005 39 Male 3/19/2009 United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 11/19/1997 Male 3/19/2009 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 3/27/2009 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 4/2/2009 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 4/14/2009 Ireland
Primary
Concomitant
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Myocardial Infarction Other Serious 7/1/2002 48 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/1/2002 48 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Virologic Failure Hospitalization 7/1/2002 48 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Virologic Failure Life Threatening 7/1/2002 49 5/5/2009 United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2001 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2001 50 Male 190 lb 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/1/2008 23 Male 8/6/2009 Physician Japan
Primary
Secondary
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 8/13/2009 Physician United States
Primary
Secondary
Stress Hospitalization 41 Male 8/13/2009 Consumer United States
Primary
Secondary
Pancreatitis Acute Other Serious 2/1/2002 Male 8/17/2009 Other Health Professional United Kingdom
Primary
Interacting
Pulmonary Hypertension Other Serious 40 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 40 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Splenomegaly Other Serious 43 Female 9/11/2009
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Splenomegaly Other Serious 57 Male 9/21/2009 Spain
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 10/1/2009 Physician United States
Primary
Secondary
Mitochondrial Toxicity Other Serious 54 Male 10/20/2009 Physician Canada
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/20/2009 Physician Canada
Primary
Secondary
Sinus Tachycardia Other Serious 7/1/2003 11/5/2009 Other Health Professional Portugal
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2003 Male 11/6/2009
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 34 Male 11/9/2009 Other Health Professional Portugal
Primary
Secondary
Demyelination Hospitalization 9/3/2007 42 Female 117 lb 11/9/2009 Physician Spain
Primary
Concomitant
Sinus Tachycardia Other Serious 7/1/2003 11/10/2009 Other Health Professional Portugal
Primary
Secondary
Weight Increased Other Serious 4/1/2001 11/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/17/2003 Male 11/16/2009 Other Health Professional Portugal
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 30 Male 11/19/2009 Other Health Professional Portugal
Primary
Secondary
Viral Load Increased Other Serious 1/1/1998 34 Male 11/19/2009 Consumer Portugal
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Myalgia Hospitalization 9/7/2001 Male 11/25/2009 Japan
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Other Serious 44 Male 12/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 12/31/2009 Physician United States
Primary
Secondary
Pyrexia Other Serious 4/25/2005 Male 1/15/2010 United States
Primary
Secondary
Concomitant
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 1/18/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/8/2010 Physician Canada
Primary
Secondary
Diffuse Large B-cell Lymphoma Other Serious 44 Male 3/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Failure Required Intervention 11/1/2004 33 Male 150 lb 3/2/2010 Cote D'ivoire
Primary
Secondary
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 3/3/2010 Italy
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/11/2010 Physician Canada
Primary
Secondary
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 3/13/2010 Physician United States
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 3/26/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/1/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/28/2010 Physician Canada
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 4/29/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/4/2010 Other Health Professional United States
Primary
Secondary
Plagiocephaly Congenital Anomaly 4 5/6/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/7/2010 Consumer United States
Primary
Secondary
Ureaplasma Infection Other Serious Female 5/10/2010 Other Health Professional Italy
Primary
Secondary
Diffuse Large B-cell Lymphoma Hospitalization 10/30/2008 44 Male 5/10/2010 Physician United States
Primary
Secondary
Vaginal Infection Other Serious Female 5/11/2010
Primary
Secondary
Small For Dates Baby Other Serious Male 5/11/2010
Primary
Secondary
Concomitant

Drug Data