Sprycel combined with Tasigna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Hospitalization 1/7/2008 Female 1/22/2008 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 1/1/2008 30 Male 5/5/2008 Physician Germany
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2008 33 Male 5/12/2008 Physician Germany
Primary
Concomitant
Weight Increased 4/25/2008 78 Female 196 lb 5/21/2008 United States
Primary
Concomitant
Weight Increased Other Serious 4/25/2008 Female 196 lb 7/1/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 4/25/2008 Female 196 lb 8/8/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 4/25/2008 78 Female 196 lb 8/7/2008 Physician United States
Primary
Concomitant
Transfusion Other Serious 5/1/2008 Female 12/8/2008 Consumer Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 8/1/2008 Female 12/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/29/2008 Physician United States
Primary
Secondary
White Blood Cells Urine Positive Other Serious Female 3/2/2009 Pharmacist United States
Primary
Secondary
Treatment Failure Other Serious 3/4/2009 Physician United States
Primary
Secondary
Headache Female 4/17/2009 Physician United States
Primary
Secondary
Treatment Failure Other Serious Female 226 lb 5/28/2009 Physician United States
Primary
Secondary
Fatigue Other Serious Male 8/26/2009 United States
Primary
Secondary
Concomitant
Leukopenia Other Serious Male 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Leukopenia Other Serious Male 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 73 Female 9/10/2009 Physician Sweden
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 10/12/2009 Physician United States
Primary
Secondary
Ventricular Fibrillation Life Threatening 8/30/2009 Female 10/15/2009 Physician Japan
Primary
Concomitant
Torsade De Pointes Other Serious 8/1/2009 Female 11/5/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious Female 11/13/2009 Physician United States
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 3/26/2009 Female 11/26/2009 Physician Japan
Primary
Concomitant
Pain Of Skin 12/22/2009 Physician Spain
Primary
Concomitant
Hyperhidrosis 8/15/2009 Male 12/28/2009 Physician Germany
Primary
Secondary
Rash Other Serious 9/1/2009 Female 116 lb 2/9/2010 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2010 2/23/2010 Physician Japan
Primary
Secondary
Troponin I Increased Other Serious 27 Female 3/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Hospitalization 7/28/2009 Male 3/26/2010 Physician Japan
Primary
Concomitant
Vomiting Female 132 lb 4/8/2010 Other Health Professional Netherlands
Primary
Secondary
Renal Cancer Other Serious 1/1/2008 66 Male 4/9/2010 Physician France
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Transformation Death 8/21/2009 79 Male 4/29/2010 Physician Japan
Primary
Concomitant
Hyperhidrosis 8/15/2009 79 Male 6/18/2010 Physician Germany
Primary
Secondary
Troponin I Increased Other Serious 27 Female 6/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Generalised Death 7/7/2009 45 Male 7/5/2010 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Male 373 lb 7/14/2010 Physician United States
Primary
Concomitant
Death Death 5/30/2010 40 Male 7/15/2010 Physician Colombia
Primary
Secondary
Platelet Count Decreased Other Serious 10/29/2009 75 Female 7/19/2010 Physician Japan
Primary
Concomitant
Stem Cell Transplant Hospitalization 25 Female 7/23/2010 Consumer Netherlands
Primary
Secondary
Chronic Myeloid Leukaemia Transformation Death 8/21/2009 79 Male 7/26/2010 Physician Japan
Primary
Concomitant
Nausea 65 Female 7/26/2010 Physician United States
Primary
Concomitant
Platelet Count Increased Other Serious 64 Female 7/26/2010 Consumer United States
Primary
Concomitant
Dyspnoea 35 Female 7/26/2010 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 7/26/2010 Physician United States
Primary
Secondary
Death Death 5/30/2010 40 Male 8/2/2010 Physician Colombia
Primary
Secondary
Drug Ineffective Male 8/24/2010 Consumer United States
Primary
Secondary
Therapeutic Response Decreased 4/1/2010 74 Male 9/7/2010 Physician Belgium
Primary
Concomitant
Platelet Count Decreased Other Serious Female 9/7/2010 United States
Primary
Concomitant
Apnoea Other Serious 56 Female 9/9/2010 Physician France
Primary
Secondary
Hypercalcaemia Female 9/13/2010 United States
Primary
Concomitant
Renal Cancer Hospitalization 6/1/2009 66 Male 220 lb 9/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/1/2008 47 Male 9/17/2010 Physician France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 40 Female 9/17/2010 Physician United States
Primary
Secondary
Vascular Graft Other Serious 10/22/2008 68 Female 10/4/2010 Physician Austria
Primary
Concomitant
Myelofibrosis Other Serious 7/27/2010 60 Female 10/11/2010 Physician Bulgaria
Primary
Secondary
Concomitant
Oedema Peripheral 8/1/2010 68 Female 10/11/2010 Consumer Taiwan, Province Of China
Primary
Secondary
Platelet Count Decreased Other Serious 60 Male 10/27/2010 Physician France
Primary
Concomitant
Rash 10/29/2010 United States
Primary
Secondary
Tinea Pedis 2/1/2009 47 Male 11/4/2010 Consumer Taiwan, Province Of China
Primary
Secondary
Thrombocytopenia Other Serious 8/12/2010 58 Male 176 lb 11/8/2010 Physician France
Primary
Concomitant
Drug Ineffective Other Serious Male 11/9/2010 United States
Primary
Secondary
Vascular Graft Other Serious 10/22/2008 68 Female 11/10/2010 Physician Austria
Primary
Concomitant
Rash 3/12/2010 57 Female 340 lb 11/25/2010 United States
Primary
Secondary
Concomitant
Cytolytic Hepatitis Other Serious 53 Female 12/23/2010 Physician France
Primary
Concomitant
Oedema Peripheral Female 12/29/2010 Consumer Taiwan, Province Of China
Primary
Secondary
Abdominal Distension 12/1/2010 69 Female 1/3/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Arthralgia Female 1/17/2011 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2009 66 Female 132 lb 2/1/2011 Physician France
Primary
Secondary
Eating Disorder Male 3/1/2011 United States
Primary
Secondary
Concomitant
Acne 12/10/2010 29 Female 3/1/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Pancreatitis Other Serious Male 3/1/2011 Consumer United States
Primary
Secondary
Concomitant
Death Death 3/22/2011 47 Female 3/28/2011 United States
Primary
Secondary
Thrombocytopenia Other Serious Female 4/12/2011 United States
Primary
Concomitant
Neoplasm Malignant Other Serious 12/1/2010 84 Female 4/15/2011 Physician France
Primary
Secondary
Blood Glucose Increased Hospitalization 69 Female 4/19/2011 Other Health Professional Austria
Primary
Concomitant
Blood Glucose Increased Hospitalization 71 Female 5/2/2011 Other Health Professional Austria
Primary
Concomitant
Breast Cancer Other Serious 12/21/2010 84 Female 154 lb 5/4/2011 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 9/3/2009 54 Female 5/6/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Intolerance 5/5/2011 Physician United Kingdom
Primary
Secondary
Gene Mutation Identification Test Positive Other Serious 12/21/2010 84 Female 154 lb 5/11/2011 Physician France
Primary
Secondary
Myositis Female 3/26/2011 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 12/1/2010 83 Female 5/12/2011 Consumer France
Primary
Secondary
Swelling Face Death 42 Male 5/13/2011 Other Health Professional United States
Primary
Secondary
Breast Cancer Hospitalization 12/1/2010 83 Female 5/23/2011 Consumer France
Primary
Secondary
Therapeutic Response Decreased Other Serious 12/21/2010 83 Female 154 lb 5/26/2011 Physician France
Primary
Secondary
Abdominal Discomfort Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 12/1/2010 83 Female 6/15/2011 Consumer France
Primary
Secondary
Hepatic Enzyme Increased Other Serious 7/1/2010 84 Male 6/20/2011 Consumer United States
Primary
Secondary
Concomitant
Abdominal Discomfort Male 6/23/2011 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 7/5/2011 Consumer France
Primary
Secondary
Liver Disorder Other Serious 4/13/2009 76 Male 152 lb 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Breast Cancer Hospitalization 12/1/2010 83 Female 7/15/2011 Consumer France
Primary
Secondary
Visual Impairment 4/1/2011 Female 7/25/2011 Consumer United States
Primary
Secondary
Adverse Event 79 Female 7/25/2011 Consumer United States
Primary
Secondary
Haemoglobin Decreased Other Serious 6/19/2009 57 Male 7/25/2011 Physician Japan
Primary
Concomitant
Malaise Male 260 lb 7/29/2011 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite 4/11/2011 59 Male 8/2/2011 Physician United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 3/1/2008 47 Male 8/3/2011 Physician France
Primary
Concomitant
Therapeutic Response Unexpected Male 8/4/2011 United States
Primary
Secondary
Concomitant
Fatigue Other Serious 5/1/2011 Male 8/4/2011 Consumer United States
Primary
Secondary
Concomitant
Fatigue Other Serious 5/1/2011 Male 8/4/2011 Consumer United States
Primary
Secondary
Concomitant
Pruritus Other Serious 1/11/2008 59 Female 8/10/2011 United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious Female 8/11/2011 Consumer United States
Primary
Secondary
Liver Disorder Other Serious 4/13/2009 76 Male 152 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Response Unexpected Male 9/6/2011 United States
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 2/24/2010 46 Female 9/7/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Neoplasm Malignant Death Male 9/12/2011 Other Health Professional France
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 9/14/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 3/1/2008 47 Male 9/15/2011 Physician France
Primary
Concomitant
Dry Skin Hospitalization Female 9/26/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Onychomycosis Male 9/27/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Oral Herpes Hospitalization 9/1/2011 35 Male 10/3/2011 Consumer Israel
Primary
Secondary
Somnolence Male 260 lb 10/6/2011 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Life Threatening 8/1/2011 54 Male 10/10/2011 Physician France
Primary
Concomitant
Fatigue Female 10/11/2011 Taiwan, Province Of China
Primary
Secondary
Blood Phosphorus Decreased Other Serious 8/13/2009 75 Male 10/18/2011 Physician Japan
Primary
Concomitant
Oral Herpes Hospitalization 9/1/2011 35 Male 10/27/2011 Consumer Israel
Primary
Secondary
Lipids Increased Other Serious Male 11/2/2011 Consumer United States
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 8/12/2010 47 Female 11/7/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Vocal Cord Polyp Male 11/8/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Constipation Other Serious 3/23/2009 63 Male 11/17/2011 Physician Japan
Primary
Concomitant
Acne 12/10/2010 29 Female 11/18/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Decreased Appetite Hospitalization Male 11/18/2011 Taiwan, Province Of China
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization Female 11/18/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Lipids Increased Other Serious Male 12/8/2011 Consumer United States
Primary
Secondary
Concomitant
Impaired Work Ability Other Serious Female 12/14/2011 United States
Primary
Secondary
Concomitant
Acne 12/10/2010 29 Female 12/15/2011 Consumer Taiwan, Province Of China
Primary
Secondary
Rash Papular Other Serious 8/13/2009 75 Male 12/27/2011 Physician Japan
Primary
Concomitant
Burning Sensation Female 2/1/2012 Consumer United States
Primary
Secondary
Neoplasm Malignant Other Serious 6/19/2009 57 Male 2/21/2012 Physician Japan
Primary
Concomitant
Pruritus Other Serious 1/11/2008 59 Female 2/27/2012 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/11/2008 59 Female 2/29/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 1/1/2008 59 Female 160 lb 2/29/2012 Physician United States
Primary
Secondary
Concomitant
Photophobia Other Serious 3/23/2009 63 Male 3/2/2012 Physician Japan
Primary
Concomitant
Drug Resistance Male 3/9/2012 Physician Thailand
Primary
Secondary
Platelet Count Decreased Hospitalization 5/27/2009 69 Female 134 lb 3/14/2012 Physician Japan
Primary
Concomitant
Burning Sensation Other Serious 8/1/2011 Female 4/16/2012 Consumer United States
Primary
Secondary
Pulmonary Oedema Other Serious 7/1/2010 85 Male 2/7/2012 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/3/2009 53 Female 2/7/2012 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 1/11/2008 60 Female 2/7/2012 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 65 Male 2/7/2012 Consumer United States
Primary
Secondary
Concomitant
Angiosarcoma Metastatic Hospitalization 9/1/2011 68 Male 187 lb 5/2/2012 Physician France
Primary
Secondary
Concomitant
Angiosarcoma Metastatic Death 68 Male 187 lb 5/7/2012 Physician France
Primary
Secondary
Pleural Effusion Other Serious 1/1/2008 68 Male 5/7/2012 Physician France
Primary
Secondary
Necrosis Ischaemic Other Serious 1/1/2008 68 Male 187 lb 5/16/2012 Consumer France
Primary
Secondary
Concomitant
Peripheral Ischaemia Hospitalization 1/1/2008 68 Male 5/16/2012 Consumer France
Primary
Secondary
Angiosarcoma Metastatic Hospitalization 68 Male 187 lb 5/16/2012 Physician France
Primary
Secondary
Muscle Spasms Female 6/6/2012 Consumer United States
Primary
Secondary
Thrombocytopenia Other Serious Female 2/10/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 11/6/2009 Physician United States
Primary
Secondary
Concomitant

Drug Data