Spironolactone combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/1999 58 Female 209 lb 1/20/2006 Lawyer United States
Primary
Concomitant
Haemoptysis Life Threatening 3/3/2003 33 Female 1/24/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/3/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Malaise Other Serious 12/18/2005 57 Female 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 12/7/2005 84 Male Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 52 Male 2/15/2006 Consumer United States
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Restrictive Pulmonary Disease Hospitalization 52 Male 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Haemodialysis Other Serious 82 Female 2/13/2006 Canada
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 2/13/2006 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 7/1/2000 76 Female 2/23/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/4/2005 87 Female 108 lb 1/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Renal Failure Chronic Life Threatening 7/1/2004 81 Male 224 lb 3/2/2006 United Kingdom
Primary
Concomitant
Renal Tubular Disorder Life Threatening 2/21/2006 37 Male 3/10/2006 United Kingdom
Primary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 3/13/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 3/3/2006 56 Female 3/16/2006 Ireland
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2003 61 Female 170 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 11/21/2005 42 Male 138 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 6/1/2003 49 Female 4/17/2006 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 52 Male 4/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Sputum Discoloured Life Threatening 3/3/2003 33 Female 5/5/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 1/1/2002 40 Male 231 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Rales Other Serious 73 Male 6/1/2006 Consumer United Kingdom
Primary
Secondary
Dyspnoea Life Threatening 5/10/2006 85 Female 138 lb 5/25/2006 Physician United States
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Syncope 1/1/2005 19 Male 104 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 1/1/2005 80 Female 182 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Visual Disturbance Hospitalization Male 4/26/2007 Consumer United States
Primary
Concomitant
Sensation Of Heaviness Hospitalization 12/25/2005 68 Male 5/17/2007 Consumer New Zealand
Primary
Concomitant
Renal Failure Other Serious 58 Male 6/22/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 8/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/1/2004 79 Female 8/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 6/1/2007 72 Male 8/21/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Hospitalization 6/1/2007 72 Male 157 lb 8/28/2007 Consumer United States
Primary
Secondary
Concomitant
Guillain-barre Syndrome Other Serious 58 Male 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Testicular Swelling Life Threatening 1/1/1999 59 Male 9/4/2007 Consumer United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 7/1/2007 71 Male 9/10/2007 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 58 Male 9/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 9/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Breast Cancer Recurrent Hospitalization 8/27/2007 56 Female 128 lb 9/20/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Disability 6/14/2007 75 Female 168 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Back Pain 3/1/2007 Male 291 lb 9/20/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 36 Female 12/27/2007 Other Health Professional Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 36 Female 1/22/2008 Other Health Professional Japan
Primary
Concomitant
Muscular Weakness Hospitalization 3/1/2008 50 Male 163 lb 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Accidental Overdose Other Serious 3/31/2008 Female 202 lb 4/18/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 2/22/2006 79 Female 5/19/2008 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/8/2008 63 Male 5/20/2008 Consumer United States
Primary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 58 Male 6/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thermal Burn Other Serious 1/1/2008 Male 280 lb 12/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Death 8/1/2008 Female 201 lb 12/24/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 12/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Ascites Hospitalization 5/30/2008 Male 12/31/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Constipation 80 Female 194 lb 1/12/2009 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/1/2008 84 Male 134 lb 1/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 1/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Thermal Burn Other Serious 1/1/2008 Male 280 lb 2/2/2009 Other Health Professional United States
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 2/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rash Death 10/1/2008 Female 2/27/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Death Female 195 lb 4/8/2009 Physician United States
Primary
Concomitant
Stent Placement Hospitalization 9/1/2008 Male 4/8/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 4/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 154 lb 4/27/2009 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Myositis Hospitalization 2/1/2009 66 Male 4/29/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/19/2005 Male 295 lb 5/6/2009 Physician United States
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 1/1/2009 Male 185 lb 5/7/2009 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 2/14/2006 Male 150 lb 5/27/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Infection Hospitalization 4/1/2009 Male 192 lb 6/3/2009 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 6/4/2009 Physician United States
Primary
Concomitant
Ascites Hospitalization 5/30/2008 Male 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Gastric Perforation Life Threatening 7/19/2008 Male 6/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 35 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Macrocytic Hospitalization 4/28/2009 49 Female 6/25/2009 Consumer Australia
Primary
Secondary
Concomitant
Anaemia Macrocytic Hospitalization 4/28/2009 49 Female 7/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Catatonia Other Serious 47 Female 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/12/2009 Portugal
Primary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 5/17/2009 72 Male 8/12/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 47 Male 8/11/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 46 Male 8/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Acute Myocardial Infarction Death 1/5/2009 Male 152 lb 8/20/2009 Physician United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Death 1/5/2009 Male 152 lb 8/20/2009 Physician United Kingdom
Primary
Concomitant
Myocardial Infarction Death 1/5/2009 Male 152 lb 8/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Macular 1/27/2009 Male 8/22/2009 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/30/2009 Female 8/24/2009 Consumer United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 6/1/2009 Male 8/28/2009 Portugal
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 7/30/2009 Female 8/28/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 456 lb 9/4/2009 United States
Primary
Concomitant
Surgery Hospitalization 47 Male 9/3/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 46 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Surgery Hospitalization 90 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Male 9/4/2009 United States
Primary
Concomitant
Stress Other Serious 1/1/2003 Male 212 lb 9/11/2009 Consumer United States
Primary
Secondary
Concomitant
Localised Infection Hospitalization Female 128 lb 9/16/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 76 Male 9/15/2009 United States
Primary
Concomitant
Weight Increased Other Serious 31 Male 9/15/2009 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2006 76 Male 215 lb 9/24/2009 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 7/30/2009 Female 9/24/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 46 Male 9/18/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/17/2009 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 7/30/2009 Female 9/30/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Hypotension Hospitalization 10/10/2009 Female 123 lb 11/11/2009 Brazil
Primary
Concomitant
Renal Impairment Hospitalization 83 Female 101 lb 11/13/2009 Physician Japan
Primary
Secondary
Concomitant
Multiple Injuries Other Serious 87 Female 12/11/2009 United States
Primary
Concomitant
Urinary Retention Hospitalization 61 Male 12/10/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 79 Male 12/11/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious Male 12/24/2009 Pharmacist
Primary
Concomitant
Pyrexia Other Serious 1/1/2009 Female 134 lb 12/29/2009 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Required Intervention 10/26/2009 56 Male 130 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2009 81 Female 125 lb 12/30/2009 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 108 lb 1/14/2010 Other Health Professional United States
Primary
Concomitant
Malaise Hospitalization 1/1/2009 53 Female 240 lb 1/15/2010 Consumer United States
Primary
Concomitant
Tibia Fracture Other Serious 78 Female 1/15/2010
Primary
Secondary
Weight Decreased Other Serious 12/1/2003 Male 159 lb 1/19/2010 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 12/15/2009 94 Male 1/19/2010 Physician Japan
Primary
Secondary
Sepsis Death Male 157 lb 1/21/2010 Physician United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 81 Female 129 lb 1/11/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2003 Male 159 lb 2/15/2010 Physician United States
Primary
Concomitant
Congenital Mitral Valve Stenosis Death 1/5/2009 2 Male 11 lb 2/24/2010 Other Health Professional Japan
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2010 Female 3/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Device Related Infection Hospitalization Female 171 lb 5/3/2010 Physician United States
Primary
Concomitant
Renal Failure Other Serious 3/4/2010 66 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Other Serious 12/26/2008 45 Female 170 lb 5/10/2010 Lawyer United States
Primary
Concomitant
Lumbar Vertebral Fracture Other Serious 85 Female 5/12/2010 Physician Greece
Primary
Secondary
Concomitant
Lung Disorder Hospitalization Male 5/17/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant

Drug Data