Spironolactone combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Other Serious 12/1/2002 79 Female 176 lb 1/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 1/7/2005 59 Male 1/18/2006 Sweden
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Renal Impairment Required Intervention 3/1/2005 49 Female 2/1/2006 Physician United States
Primary
Concomitant
Nausea Other Serious 11/1/2005 38 Female 2/1/2006 Physician Israel
Primary
Concomitant
Fall Other Serious 1/12/2006 85 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 106 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2005 58 Male 2/13/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Other Serious 63 Male 230 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 89 Male 2/16/2006 United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 5/27/2004 50 Female 223 lb 2/21/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Nausea Other Serious 11/1/2005 38 Female 3/3/2006 Physician Israel
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/9/2006 Physician Japan
Primary
Concomitant
Syncope Other Serious 1/1/2005 58 Male 3/10/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2005 58 Male 193 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/24/2006 Physician Japan
Primary
Concomitant
Bradycardia Hospitalization 84 3/24/2006 Physician Czech Republic
Primary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 4/4/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Death 9/9/2004 73 Male 3/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 3/15/2006 29 Female 78 lb 4/11/2006 Physician Japan
Primary
Concomitant
Neck Pain Death 2/16/2006 82 Male 205 lb 4/4/2006 Consumer United States
Primary
Concomitant
Epistaxis Hospitalization 2/2/2006 54 Female 179 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Pneumonia Hospitalization 12/30/2004 59 Male 4/20/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 4/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Sclerosis Other Serious 1/1/2004 58 Male 4/25/2006 Denmark
Primary
Concomitant
Road Traffic Accident Other Serious 3/20/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Haemodialysis Hospitalization 1/13/2004 82 Female 4/26/2006 Canada
Primary
Concomitant
Pneumonia Life Threatening 3/3/2006 56 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Skin Ulcer Hospitalization Female 197 lb 5/8/2006 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 73 Male 5/5/2006 Physician United Kingdom
Primary
Secondary
Drug Interaction Other Serious 6/24/2005 68 Female 187 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 56 Female 5/12/2006 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/13/2006 78 Male Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 1/14/2006 64 Male Pharmacist United States
Primary
Concomitant
Medication Error Hospitalization 8/1/2000 68 Female 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 73 Male 5/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Malaise Hospitalization 11/17/2005 59 Female 99 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization Female 197 lb 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 11/8/2001 12 Male 66 lb 6/7/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 6/2/2006 Physician Australia
Primary
Concomitant
Hypoglycaemia Hospitalization 5/1/2006 70 Female 130 lb 6/15/2006 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sinusitis 28 Female 120 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 1/19/2006 54 Female 120 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Endophthalmitis Other Serious 4/27/2006 80 Female 6/19/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 11/17/2005 35 Female 6/19/2006 Pharmacist Canada
Primary
Concomitant
Nausea 6/7/2006 58 Male 160 lb 6/15/2006 Pharmacist United States
Primary
Concomitant
Skin Ulcer Life Threatening Female 197 lb 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Sensation Of Heaviness 1/30/2006 64 Female 153 lb 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Atrial Fibrillation 6/1/2005 64 Female 153 lb 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Presbyacusis Disability 10/15/2005 84 Male 6/23/2006 Other Health Professional Sweden
Primary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Vitamin B12 Deficiency Other Serious 74 Male 7/3/2006 United States
Primary
Concomitant
Pancytopenia Required Intervention 74 Male 7/5/2006 Physician United States
Primary
Concomitant
Asthma Hospitalization 10/6/2005 31 Female 7/18/2006 Physician Japan
Primary
Concomitant
Throat Tightness Hospitalization 10/13/2005 49 Female 157 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 7/21/2006 85 Female 180 lb 7/26/2006 Pharmacist United States
Primary
Concomitant
Skin Ulcer Life Threatening Female 197 lb 7/28/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
Tearfulness Required Intervention 77 Female 7/26/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 7/7/2006 59 Female 118 lb 7/21/2006 Physician Canada
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Haemoptysis 1/4/2006 83 Female 5/24/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Required Intervention 7/30/2006 76 Female 118 lb 8/6/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Myocardial Infarction Hospitalization 73 Male 8/11/2006 Brazil
Primary
Concomitant
Vulval Disorder Hospitalization 8/2/2006 29 Female 108 lb 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Urticaria Hospitalization 8/2/2006 29 Female 108 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fluid Retention Other Serious 1/1/2006 70 Female 192 lb 7/19/2006 Physician United States
Primary
Concomitant
Respiratory Rate Increased Hospitalization 42 Female 8/28/2006 Italy
Primary
Concomitant
Tremor 49 Female 160 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Lesion Hospitalization 8/2/2006 29 Female 108 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged 3/8/2006 76 Male 9/6/2006 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 8/28/2006 38 Male 225 lb 9/7/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 9/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 9/7/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence 4/24/2006 60 Female 180 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 42 Female 9/4/2006 Physician Italy
Primary
Concomitant
Mobility Decreased Other Serious 6/4/2006 83 Female 9/11/2006 Other Health Professional United Kingdom
Primary
Concomitant
Blood Amylase Increased Other Serious 5/1/2005 78 Male 9/5/2006 United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 42 Female 9/18/2006 Physician Italy
Primary
Concomitant
International Normalised Ratio Abnormal Life Threatening 6/4/2006 89 Male 155 lb 6/5/2006 Pharmacist United States
Primary
Concomitant
Streptococcal Infection Hospitalization 7/23/2005 45 Male 237 lb 9/21/2006 Other Health Professional United States
Primary
Concomitant
Arterial Occlusive Disease Hospitalization 3/31/2006 68 Male 9/27/2006 Other Health Professional
Primary
Concomitant
Pneumonia Other Serious 8/29/2006 18 Female 130 lb 9/25/2006 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/27/2006 62 Male 230 lb 9/29/2006 Pharmacist United States
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/5/2006
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization 7/7/2006 82 Male 192 lb 10/4/2006 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 3/31/2006 Male 10/9/2006 Other Health Professional
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/10/2006 Physician
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 5/8/2006 25 Female 10/5/2006 France
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/18/2006 77 Female 213 lb 10/5/2006 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 52 Female 10/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 10/16/2006 Physician
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 78 Male 10/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hyperkalaemia Required Intervention 78 Male 10/10/2006 Other Health Professional Denmark
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 88 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Life Threatening 4/7/2006 Female 197 lb 10/20/2006 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/14/2006 69 Female 121 lb 10/11/2006 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 74 Female 10/23/2006 Physician
Primary
Secondary
Concomitant
Neutropenia Other Serious 74 Female 175 lb 10/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/24/2006 18 Female 130 lb 10/18/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Visual Disturbance 4/27/2006 81 Female 10/27/2006 Other Health Professional United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Haemorrhage Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Hospitalization 4/27/2006 56 Female 10/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/2/2006 91 Female 86 lb 10/26/2006 Physician Japan
Primary
Concomitant
Wound Infection Other Serious 3/1/2006 60 Female 105 lb 10/30/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Drug Administration Error Male 11/13/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 11/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/27/2006 59 Male 223 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Skin Necrosis Hospitalization 7/1/2003 75 Female 11/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/25/2006 Male 200 lb 9/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Urinary Tract Other Serious 11/6/2006 Female 150 lb 12/20/2006 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 6/30/2006 63 Male 121 lb 12/18/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 9/1/2006 80 Male 12/28/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Death 11/22/2005 41 Male 170 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Visual Disturbance 6/19/2006 86 Female 200 lb 10/11/2006 Consumer United States
Primary
Concomitant
Overdose Other Serious 11/30/2005 69 Female 8/21/2006 Pharmacist United States
Primary
Concomitant
Weight Increased 1/1/2006 75 Female 10/19/2006 Pharmacist United States
Primary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gingival Bleeding 7/18/2006 40 Female 235 lb 10/24/2006 United States
Primary
Secondary
Concomitant

Drug Data