Spironolactone combined with Verapamil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Right Ventricular Failure Hospitalization 7/3/2003 Female 1/4/2006 France
Primary
Concomitant
Malaise Hospitalization 12/9/2005 2/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Nephrolithiasis Hospitalization 2/4/2006 61 Female 290 lb 3/28/2006 Consumer Canada
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
Nephrolithiasis Hospitalization 1/1/1996 62 Female 290 lb 4/6/2006 Canada
Primary
Secondary
Concomitant
Radicular Syndrome Life Threatening 2/1/2004 65 Male 5/9/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 6/24/2005 68 Female 187 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Tremor 3/17/2006 67 Male 5/30/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 1/8/2001 63 Male 7/24/2006 France
Primary
Secondary
Concomitant
Sepsis Other Serious 5/7/2005 71 Female 209 lb 8/10/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Oedema Peripheral 8/1/2005 68 Male 11/30/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 66 Female 3/7/2007 Consumer United States
Primary
Concomitant
Myositis Other Serious 2/1/2007 64 Female 220 lb 3/14/2007 United Kingdom
Primary
Secondary
Concomitant
Urethral Haemorrhage Other Serious 1/1/2006 Male 165 lb 4/5/2007 Physician Germany
Primary
Concomitant
Visual Disturbance Hospitalization Male 4/26/2007 Consumer United States
Primary
Concomitant
Hypotension Life Threatening 77 Female 5/2/2007 United Kingdom
Primary
Concomitant
Renal Failure Acute Life Threatening 8/27/2006 72 Male 5/2/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 10/16/2006 66 Male 187 lb 2/9/2007 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 263 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/6/2007 Male 9/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Acute Required Intervention 6/1/2007 80 Female 176 lb 9/14/2007 Consumer United States
Primary
Concomitant
Weight Decreased 57 Female 263 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/24/2007 70 Male 10/24/2007 Consumer United States
Primary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Vitamin B6 Deficiency Other Serious 1/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myalgia Disability 8/1/2007 1/23/2008 Consumer United States
Primary
Concomitant
Vitreous Floaters Death 12/7/2007 53 Male 231 lb 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Disability 8/1/2007 82 Female 144 lb 2/29/2008 United Kingdom
Primary
Secondary
Concomitant
Paraesthesia 9/27/2007 53 Female 145 lb 1/10/2008 Consumer United States
Primary
Concomitant
Myalgia Disability 8/1/2007 82 Female 3/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 84 Female 3/19/2008 Italy
Primary
Concomitant
Oedema Peripheral Other Serious 9/12/2007 78 Female 126 lb 4/11/2008 Physician United States
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization 40 Female 4/21/2008 Physician France
Primary
Concomitant
Swelling Other Serious 3/20/2008 Female 131 lb 4/28/2008 Other Health Professional United States
Primary
Concomitant
Throat Tightness Other Serious 3/20/2008 Female 131 lb 5/30/2008 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 3/20/2008 Female 131 lb 7/11/2008 Physician United States
Primary
Concomitant
Night Sweats 1/1/2008 Female 120 lb 7/25/2008 Consumer United States
Primary
Concomitant
Retroperitoneal Haematoma Other Serious 9/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 62 Female 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Other Serious 62 Female 9/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Female 271 lb 12/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 9/9/2008 Female 162 lb 12/12/2008 Consumer United States
Primary
Concomitant
Weight Increased 2/1/2008 Female 200 lb 12/18/2008 Consumer United States
Primary
Concomitant
Local Swelling 6/5/2008 47 Female 212 lb 12/18/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 11/14/2008 Male 330 lb 12/19/2008 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/9/2008 Female 237 lb 12/23/2008 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 9/9/2008 Female 237 lb 1/15/2009 Other Health Professional United States
Primary
Concomitant
Erythromelalgia Other Serious 3/17/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/30/2008 58 Female 3/17/2009 Netherlands
Primary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/15/2004 49 Male 276 lb 4/21/2009 United States
Primary
Concomitant
Weight Increased Other Serious 12/8/1997 50 Female 5/15/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 5/20/2009 Physician United States
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 5/29/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 6/1/2009 Physician United States
Primary
Concomitant
Interacting
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 6/3/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/12/2009 Female 130 lb 6/10/2009 United States
Primary
Concomitant
Headache Other Serious 6/1/2009 Female 280 lb 6/30/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/1/2009 Female 7/2/2009 Physician United States
Primary
Concomitant
Interacting
Headache Other Serious 6/1/2009 Female 280 lb 7/16/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Death 86 Female 7/20/2009 United States
Primary
Concomitant
Radiation Skin Injury Other Serious 5/16/2002 Female 8/21/2009 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Female 8/22/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 8/18/2009 United States
Primary
Concomitant
Pulmonary Congestion Other Serious 1/8/2008 64 Female 8/25/2009 Consumer United Kingdom
Primary
Concomitant
Tongue Injury Other Serious 6/30/2009 Female 237 lb 9/2/2009 Physician United States
Primary
Concomitant
Pain Hospitalization 67 Male 8/31/2009 United States
Primary
Concomitant
Injection Site Pain 9/9/2008 Female 162 lb 9/12/2009 Consumer United States
Primary
Concomitant
Pain Hospitalization 67 Male 9/8/2009 United States
Primary
Concomitant
Vomiting Other Serious 9/4/2009 Female 125 lb 9/4/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 9/15/2009 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/1/2008 78 Female 165 lb 9/24/2009 Netherlands
Primary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 67 Male 9/24/2009 United States
Primary
Concomitant
Headache Other Serious 6/1/2009 Female 280 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 8/6/2009 Female 10/14/2009 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/10/2009 United States
Primary
Concomitant
Pain Hospitalization 67 Male 10/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/18/2009 United States
Primary
Concomitant
Tooth Loss Other Serious 8/6/2009 Female 10/26/2009 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/22/2009 Consumer United States
Primary
Concomitant
Pulmonary Congestion Other Serious 3/1/2008 64 Female 11/2/2009 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/26/2009 Lawyer United States
Primary
Concomitant
Rhesus Antibodies Positive 5/13/2008 79 Male 146 lb 10/24/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 11/4/2009 United States
Primary
Concomitant
Tenderness Other Serious 11/20/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 67 Male 11/18/2009 United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 11/25/2009 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Death 9/21/2008 52 Male 11/30/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 12/1/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 84 Female 12/22/2009 Physician Italy
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2009 77 Male 1/15/2010 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 66 Male 1/22/2010 United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2009 77 Male 2/23/2010 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 2/5/2010 United States
Primary
Concomitant
Oedema Hospitalization Female 145 lb 2/24/2010 Consumer United States
Primary
Concomitant
Oedema Hospitalization Female 145 lb 3/9/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization Female 145 lb 3/15/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization Female 3/22/2010 United States
Primary
Concomitant
Oedema Hospitalization 2/11/2010 Female 145 lb 3/24/2010 Physician United States
Primary
Concomitant
Dehydration Other Serious 2/17/2009 69 Male 249 lb 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Throat Irritation 57 Female 4/23/2010 Physician United States
Primary
Secondary
Concomitant
Tinnitus 58 Male 277 lb 5/3/2010 Consumer United States
Primary
Concomitant
Interacting
Von Willebrand's Factor Antigen Increased Other Serious 10/1/2009 56 Female 119 lb 5/19/2010 Physician Hungary
Primary
Concomitant
Wheezing Hospitalization 81 Male 6/2/2010 United States
Primary
Concomitant
Diarrhoea 1/1/2008 77 Female 199 lb 6/23/2010 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 2/27/2010 70 Female 176 lb 6/25/2010 Pharmacist United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Contraindication To Medical Treatment 1/1/2007 64 Female 162 lb 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 5/19/2009 78 Female 6/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor 1/1/2007 55 Female 170 lb 7/14/2010 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/31/2010 65 Female 198 lb 7/16/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/1/2007 75 Male 235 lb 7/16/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/31/2010 65 Female 198 lb 7/21/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 2/2/2010 63 Male 216 lb 8/26/2010 Physician Netherlands
Primary
Concomitant
Dizziness 3/1/2010 46 Male 8/28/2010 United States
Primary
Concomitant
Vomiting Other Serious 5/31/2010 65 Female 198 lb 8/30/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Inappropriate Schedule Of Drug Administration 1/1/2010 73 Female 170 lb 9/2/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 6/17/2010 66 Male 284 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetes Mellitus Death 9/21/2008 52 Male 9/16/2010 Lawyer United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/31/2010 65 Female 198 lb 10/8/2010 Physician Czech Republic
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 75 Male 10/19/2010 Other Health Professional Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 5/31/2010 65 Female 198 lb 11/5/2010 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/2/2010 63 Male 216 lb 11/5/2010 Physician Netherlands
Primary
Concomitant
Flushing 10/13/2010 51 Male 11/16/2010 Consumer United States
Primary
Concomitant
Erectile Dysfunction 61 Male 11/16/2010 Consumer United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 11/18/2009 79 Male 330 lb 3/1/2010 Other Health Professional United States
Primary
Concomitant
Road Traffic Accident Death 2/20/2008 52 Male 228 lb 1/28/2011 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 80 Male 1/28/2011 United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Radial Pulse Decreased Death 70 Female 119 lb 3/11/2011 Other Health Professional Brazil
Primary
Secondary
Concomitant
Malaise Death 2/20/2008 52 Male 228 lb 3/4/2011 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 3/15/2011 Other Health Professional Denmark
Primary
Concomitant
Abdominal Distension Hospitalization 9/28/2007 3/23/2011 Physician United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Death 2/20/2008 52 Male 228 lb 3/15/2011 Lawyer United States
Primary
Concomitant
Respiratory Arrest Death 2/20/2008 52 Male 228 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Blindness Transient Hospitalization 3/1/2011 49 Female 201 lb 4/6/2011 Consumer United States
Primary
Concomitant
Urine Odour Abnormal Hospitalization 9/28/2007 4/11/2011 Other Health Professional United States
Primary
Concomitant
Bradycardia Life Threatening 3/5/2011 79 Male 161 lb 4/13/2011 Physician Ireland
Primary
Secondary
Concomitant
Myocardial Infarction Death Female 141 lb 4/19/2011 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/1/2011 49 Female 201 lb 4/25/2011 Consumer United States
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 4/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 3/1/2011 49 Female 201 lb 4/29/2011 Consumer United States
Primary
Concomitant
Anticonvulsant Drug Level Above Therapeutic Hospitalization 64 Female 4/25/2011 United States
Primary
Concomitant
Bradycardia Hospitalization 3/5/2011 79 Male 161 lb 5/6/2011 Physician Ireland
Primary
Secondary
Concomitant

Drug Data