Spironolactone combined with Valsartan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Venoocclusive Disease Life Threatening 11/23/2005 63 Female 121 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 33 Female 1/25/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 2/23/2002 46 Male 3/22/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Periarthritis Hospitalization 8/13/2001 64 Female 170 lb 5/9/2006 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 3/17/2006 73 Female 210 lb 4/20/2006 United States
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/31/2006 Female 159 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 3/17/2006 73 Female 210 lb 7/19/2006 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Subileus Other Serious 77 Male 10/9/2006 Physician Japan
Primary
Concomitant
Renal Failure Chronic Hospitalization 10/10/2006 64 Male 12/12/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 64 Male 12/22/2006 Physician Germany
Primary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Sepsis Death 11/1/2006 85 Male 2/5/2007 Physician Japan
Primary
Concomitant
Sepsis Disability 11/1/2006 85 Female 2/16/2007 Physician Japan
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Ventricular Asystole Life Threatening 2/4/2006 85 Female 1/2/2007 United States
Primary
Secondary
Concomitant
Myalgia 11/8/2006 71 Female 116 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/5/2007 65 Male 4/20/2007 Japan
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/2/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/26/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/12/2007 77 Female 4/28/2007 United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious Female 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/11/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 5/25/2007 Physician Japan
Primary
Secondary
Concomitant
Supraventricular Extrasystoles Other Serious 1/5/2007 65 Male 5/21/2007 Japan
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 183 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 6/9/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 135 lb 7/12/2007 Physician United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 5/5/2007 72 Male 8/2/2007 Pharmacist United States
Primary
Secondary
Insomnia 6/13/2007 76 Male 325 lb 7/10/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 Male 9/4/2007 Germany
Primary
Concomitant
Wheezing Other Serious 1/1/2007 Female 180 lb 9/7/2007 Consumer United States
Primary
Concomitant
Back Pain 3/1/2007 Male 291 lb 9/20/2007 Consumer United States
Primary
Concomitant
Lethargy Hospitalization 9/15/2007 Male 196 lb 10/10/2007 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/15/2007 Male 196 lb 10/19/2007 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 9/13/2007 Male 196 lb 10/25/2007 Physician United Kingdom
Primary
Concomitant
Muscle Haemorrhage Hospitalization 9/17/2007 Male 11/16/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiovascular Disorder Hospitalization 10/15/2007 66 Female 11/21/2007 Physician Russian Federation
Primary
Concomitant
Confusional State Hospitalization 10/25/2007 12/6/2007 Consumer United Kingdom
Primary
Concomitant
Muscle Haemorrhage Hospitalization 9/17/2007 Male 1/11/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2007 Female 152 lb 1/25/2008 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/1/2007 Female 152 lb 2/19/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment 82 Male 4/22/2008 Germany
Primary
Concomitant
Haemoglobin Abnormal Hospitalization 2/20/2008 71 Female 5/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Abnormal Hospitalization 2/20/2008 71 Female 5/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Abnormal Other Serious 2/20/2008 71 Female 5/20/2008 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment 7/20/2007 82 Male 5/30/2008 Physician Germany
Primary
Concomitant
Vomiting Death 4/2/2008 55 Male 170 lb 6/3/2008 United States
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 6/12/2008 Consumer United States
Primary
Concomitant
Mobility Decreased 4/23/2008 Female 145 lb 6/13/2008 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/10/2006 Male 7/11/2008 Germany
Primary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 7/23/2008 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 Male 9/25/2008 Physician Japan
Primary
Secondary
Concomitant
Wheezing Hospitalization 75 Male 162 lb 10/14/2008 United States
Primary
Secondary
Concomitant
Memory Impairment Required Intervention 3/1/2008 52 Female 158 lb 10/16/2008 Consumer United States
Primary
Concomitant
Memory Impairment Other Serious 3/1/2008 52 Female 185 lb 11/5/2008 Other Health Professional United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 11/28/2007 80 Male 3/4/2009 Physician Germany
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/21/2009 64 Female 233 lb 4/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 79 Male 5/6/2009 Physician United States
Primary
Concomitant
Myoclonus Other Serious 79 Male 5/18/2009 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 79 Male 5/22/2009
Primary
Secondary
Concomitant
Myoclonus Other Serious 79 Male 5/25/2009 Other Health Professional United States
Primary
Concomitant
Myoclonus Hospitalization 79 Male 6/3/2009 Other Health Professional United States
Primary
Concomitant
Myoclonus Hospitalization 79 Male 5/29/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 79 Male 6/23/2009 United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 4/1/2009 55 7/24/2009 Pharmacist Canada
Primary
Concomitant
Oedema Hospitalization 63 Female 7/21/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 65 Male 8/6/2009 United States
Primary
Concomitant
Pruritus 11/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus 2/19/2009 Male 8/22/2009 United States
Primary
Concomitant
Joint Contracture 3/13/2008 Female 186 lb 9/12/2009 Consumer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 65 Male 9/9/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 10/14/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 63 Female 11/18/2009 United States
Primary
Concomitant
Pseudoaldosteronism Hospitalization 7/23/2008 Male 99 lb 12/3/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 12/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 65 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Sudden Death Death 2/2/2010 81 Female 2/23/2010 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 68 Male 207 lb 2/12/2010 Other Health Professional Canada
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious Male 4/5/2010 Physician United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 3/16/2010 65 Male 253 lb 4/2/2010 Pharmacist United States
Primary
Secondary
Myalgia Other Serious 2/1/2010 73 Female 163 lb 4/9/2010 Consumer Sweden
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 4/19/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Female 212 lb 5/11/2010 Physician
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 143 lb 7/1/2010 Physician Japan
Primary
Concomitant
Renal Pain Other Serious 10/21/2006 49 Female 225 lb 7/8/2010 Consumer United States
Primary
Concomitant
Tension 3/1/2007 63 Female 7/12/2010 Consumer United States
Primary
Concomitant
Completed Suicide Death 4/1/2008 51 Male 188 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 6/1/2008 48 Female 7/22/2010 Other Health Professional United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 143 lb 7/23/2010 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious Male 260 lb 7/31/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2008 67 Male 178 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 1/1/2008 63 Female 241 lb 8/6/2010 Consumer United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 143 lb 8/17/2010 Physician Japan
Primary
Concomitant
Urticaria Other Serious 12/11/2009 66 Male 276 lb 8/28/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2009 68 Female 104 lb 8/30/2010 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious Male 143 lb 9/10/2010 Physician Japan
Primary
Concomitant
Product Quality Issue Other Serious 1/1/2010 91 Female 105 lb 9/14/2010 Consumer United States
Primary
Concomitant
Breast Tenderness 9/15/2010 Consumer United States
Primary
Concomitant
Septic Shock Hospitalization 7/24/2010 84 Male 9/17/2010 Physician Brazil
Primary
Secondary
Concomitant
Palpitations Other Serious 4/14/2010 79 Female 145 lb 10/1/2010 Consumer United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 4/27/2010 37 Male 143 lb 10/6/2010 Physician Japan
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 6/14/2010 65 Female 160 lb 11/8/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 4/27/2010 37 Male 143 lb 11/16/2010 Physician Japan
Primary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/24/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 42 Male 11/29/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 9/9/2010 83 Male 179 lb 11/30/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperlipidaemia Life Threatening 9/26/2002 42 Male 12/7/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/19/2011 Physician Saudi Arabia
Primary
Secondary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 9/1/2010 62 Female 1/19/2011 Other Health Professional France
Primary
Concomitant
Pupillary Reflex Impaired Life Threatening 1/13/2011 28 Female 1/21/2011 Physician China
Primary
Concomitant
Drug Interaction Death 53 Male 128 lb 1/24/2011 Other Health Professional Saudi Arabia
Primary
Concomitant
Interacting
Blood Pressure Immeasurable Life Threatening 1/13/2011 28 Female 96 lb 2/8/2011 Other Health Professional China
Primary
Concomitant
Aspartate Aminotransferase Increased Death 6/5/2010 80 Female 158 lb 2/18/2011 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 42 Female 2/24/2011 Physician United States
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Urea Nitrogen/creatinine Ratio Increased Hospitalization 12/13/2010 71 Male 2/18/2011 Other Health Professional United States
Primary
Secondary
Pulse Absent Life Threatening 1/13/2011 28 Female 96 lb 3/10/2011 Other Health Professional China
Primary
Concomitant
Cerebrovascular Accident Hospitalization 3/13/2011 79 Male 154 lb 3/17/2011 Physician Malaysia
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 3/15/2011 Other Health Professional Denmark
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Intestinal Obstruction Other Serious 4/14/2010 79 Female 145 lb 3/25/2011 Consumer United Kingdom
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 3/13/2011 79 Male 154 lb 3/30/2011 Physician Malaysia
Primary
Concomitant
Colitis Hospitalization 9/26/2002 42 Male 3/31/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/24/2010 84 Male 4/6/2011 Physician Brazil
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 2/18/2011 76 Female 3/31/2011 Other Health Professional Denmark
Primary
Concomitant
Blood Sodium Decreased Hospitalization 10/7/2008 72 Male 4/7/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 4/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Concomitant Disease Aggravated Other Serious 2/16/2010 81 Female 95 lb 6/1/2011 Physician Japan
Primary
Concomitant
Fall Death 2/5/2010 77 Male 6/1/2011 Consumer United Kingdom
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2006 62 Female 6/2/2011 Physician Italy
Primary
Secondary
Concomitant
Ventricular Hypokinesia Death 53 Male 128 lb 6/20/2011 Other Health Professional Saudi Arabia
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 80 Male 6/22/2011 Other Health Professional
Primary
Secondary
Concomitant
Dizziness Female 7/5/2011 Consumer United States
Primary
Secondary
Atrial Fibrillation Other Serious 80 Male 6/28/2011 Other Health Professional Belgium
Primary
Secondary
Concomitant
Peripheral Motor Neuropathy Other Serious 80 Male 7/5/2011 Other Health Professional
Primary
Secondary
Concomitant
Prothrombin Time Ratio Increased Other Serious 50 Female 99 lb 8/5/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Renal Disorder Other Serious 4/28/2010 Female 154 lb 8/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Mental Disorder Other Serious 1/1/2011 63 Female 187 lb 8/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 4/28/2010 Female 154 lb 8/12/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Amnesia Other Serious 4/28/2010 Female 154 lb 8/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Macular Degeneration Other Serious 4/28/2010 Female 154 lb 8/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 8/18/2009 75 Male 8/26/2011 Consumer South Africa
Primary
Concomitant
Paranoia Other Serious 1/1/2011 64 Female 187 lb 8/26/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arthralgia Other Serious 4/28/2010 Female 154 lb 8/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data