Spironolactone combined with Ursodiol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 5/12/2006 Physician United States
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 5/30/2006 Physician United States
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 6/19/2006 Physician United States
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 7/27/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/8/2006 36 Male 279 lb 7/11/2006 Pharmacist United States
Primary
Concomitant
Back Pain 6/13/2006 35 Female 9/27/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 10/19/2006 54 Female 2/21/2007 Japan
Primary
Secondary
Concomitant
Varices Oesophageal Death 3/22/2006 Male 4/3/2007 United Kingdom
Primary
Concomitant
Hepatitis B Other Serious 10/6/2004 57 Male 4/6/2007 Physician Japan
Primary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 5/15/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 5/22/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 6/4/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/24/2007 Male 143 lb 6/15/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Seroma Hospitalization 1/9/2006 Female 150 lb 9/5/2007 Physician Switzerland
Primary
Concomitant
Seroma Hospitalization 4/20/2006 Female 152 lb 9/6/2007 Physician Switzerland
Primary
Concomitant
Rash Erythematous Other Serious 8/15/2007 1 Female 26 lb 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/29/2007 69 Male 135 lb 9/21/2007 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 11/1/2007 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 11/5/2007 Japan
Primary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 11/8/2007 Japan
Primary
Concomitant
Seroma Hospitalization 1/9/2006 Female 150 lb 12/3/2007 Physician Switzerland
Primary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 12/5/2007 Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/8/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/22/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 5/1/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 7/3/2008 Physician Japan
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/26/2007 0 Female 6 lb 6/15/2008 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/26/2007 0 Female 6 lb 6/25/2008 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Vomiting Hospitalization 6/30/2008 74 Female 192 lb 8/14/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/19/2008 Male 9/4/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/30/2008 74 Female 192 lb 9/4/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/19/2008 56 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/30/2008 74 Female 192 lb 9/15/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/19/2008 56 Male 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 5/19/2008 56 Male 10/21/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 10/31/2008 Japan
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 8/14/2008 12/24/2008 Japan
Primary
Secondary
Concomitant
Adverse Drug Reaction Hospitalization Female 150 lb 12/30/2008 Consumer United States
Primary
Concomitant
Portal Vein Thrombosis Hospitalization 8/14/2008 2/3/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Hospitalization 12/14/2008 Female 150 lb 2/5/2009 Physician United States
Primary
Concomitant
Pruritus Generalised Other Serious 1/1/2009 Female 110 lb 2/17/2009 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 12/21/2005 Male 3/4/2009 Japan
Primary
Concomitant
Transfusion Reaction Hospitalization 3/10/2006 51 Female 160 lb 3/2/2009 Physician United States
Primary
Concomitant
Seborrhoeic Dermatitis Other Serious 12/1/2008 57 Male 119 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Cardiac Failure Chronic Hospitalization 8/24/2004 67 Female 106 lb 6/29/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/22/2006 69 Female 110 lb 7/2/2009 Physician Japan
Primary
Concomitant
Anaphylactoid Reaction Other Serious 6/18/2009 71 Male 7/22/2009 Other Health Professional Japan
Primary
Concomitant
Weight Decreased Hospitalization 6/30/2008 74 Female 192 lb 7/23/2009 Physician United States
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 6/18/2009 71 Male 8/11/2009 Other Health Professional Japan
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 5/1/2009 Female 190 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Other Serious 3/29/2007 69 Male 135 lb 9/17/2009 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/21/2009 71 Male 137 lb 9/29/2009 Korea, Republic Of
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 72 Female 9/24/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/6/2009 United States
Primary
Secondary
Concomitant
Urinary Hesitation Hospitalization 7/28/2008 65 Male 207 lb 10/5/2009 Physician United States
Primary
Secondary
Concomitant
Periodontitis Hospitalization 32 146 lb 10/29/2009 Physician Germany
Primary
Concomitant
Periodontitis Hospitalization 32 146 lb 11/2/2009 Physician Germany
Primary
Concomitant
Medication Error 10/21/2009 69 Female 184 lb 12/22/2009 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 11/1/2009 15 Female 3/8/2010 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 3/26/2010 71 Male 4/1/2010 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 3/26/2010 71 Male 4/7/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/11/2009 47 Male 185 lb 4/14/2010 United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/1/2009 67 Female 5/19/2010 Consumer United States
Primary
Secondary
Concomitant
Venous Insufficiency Other Serious 3/15/2010 53 Female 145 lb 5/24/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 176 lb 6/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 28 Male 6/11/2010 Lawyer United States
Primary
Concomitant
Venoocclusive Disease Other Serious 5/13/2010 31 Female 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 7/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 3/7/2006 69 Female 110 lb 6/30/2010 Physician Japan
Primary
Concomitant
Condition Aggravated Hospitalization 8/24/2004 67 Female 106 lb 7/7/2010 Physician Japan
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 7/21/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 7/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Jaundice Other Serious 3/17/2010 70 Female 7/27/2010 Japan
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 66 Male 119 lb 8/10/2010 Consumer Japan
Primary
Secondary
Flushing 12/17/2009 62 Female 174 lb 8/28/2010 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious Female 9/2/2010 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4/30/2010 32 Female 9/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Depressed Level Of Consciousness Other Serious 5/29/2010 7 Male 54 lb 9/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Hospitalization 4/30/2010 31 Female 9/8/2010 Other Health Professional United States
Primary
Concomitant
Venoocclusive Disease Other Serious 4/30/2010 31 Female 176 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Restlessness Required Intervention 53 Female 9/21/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 53 Female 9/28/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/1/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 1/1/2008 53 Male 245 lb 11/1/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Other Serious 10/17/2010 77 Male 134 lb 11/9/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 4/8/2010 Female 12/2/2010 Consumer China
Primary
Concomitant
Urticaria Hospitalization 6/24/2010 44 Female 12/1/2010 Pharmacist United States
Primary
Concomitant
Anaphylactic Shock Life Threatening 9/22/2010 78 Male 160 lb 12/15/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 7/13/2009 54 Male 161 lb 1/14/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 7/13/2009 54 Male 161 lb 1/19/2011 Physician Japan
Primary
Secondary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Injection Site Pain 6/2/2010 66 Female 1/29/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission 9/3/2010 65 Female 1/30/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 12/14/2007 69 Male 187 lb 1/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 59 Male 3/17/2011 Physician India
Primary
Concomitant
Atelectasis Hospitalization 3/17/2011 2 Female 32 lb 3/23/2011 United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization Female 259 lb 4/19/2011 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Pain In Jaw 49 Male 132 lb 5/19/2011 Consumer United States
Primary
Concomitant
Pericardial Effusion Hospitalization 3/17/2011 2 Female 32 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Gingivitis Other Serious 1/1/2005 32 Female 6/22/2011 Other Health Professional Romania
Primary
Secondary
Abdominal Pain Hospitalization 53 Female 6/15/2011 Pharmacist United States
Primary
Secondary
Hepatic Encephalopathy Hospitalization 53 Female 6/20/2011 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/26/2011 61 Female 6/22/2011 Consumer United States
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/8/2011 47 Male 6/26/2011 Other Health Professional Japan
Primary
Secondary
Oesophageal Varices Haemorrhage Hospitalization 1/22/2009 53 Female 7/6/2011 Pharmacist United States
Primary
Secondary
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Artery Thrombosis Other Serious 12/1/2009 45 Male 7/22/2011 Consumer United States
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 6/24/2009 64 Female 121 lb 8/12/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Other Serious 8/15/2011 38 Male 9/6/2011 Consumer United States
Primary
Concomitant
Hepatic Failure Other Serious 8/15/2011 38 Male 9/19/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 12/1/2009 45 Male 9/28/2011 Consumer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 8/15/2011 38 Male 128 lb 10/3/2011 Consumer United States
Primary
Concomitant
Biliary Cirrhosis Primary Hospitalization 5/28/2009 55 Female 128 lb 10/7/2011 Physician Japan
Primary
Concomitant
Mental Disorder Hospitalization 11/1/2006 43 Female 10/4/2011 United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 1/1/2011 4 Male 37 lb 10/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haematemesis Other Serious 4 Male 38 lb 10/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Anaemia Life Threatening 69 Male 187 lb 10/31/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Hospitalization 5/21/2007 49 Female 132 lb 11/3/2011 Physician Japan
Primary
Concomitant
Cholelithiasis Death 12/1/2007 54 Male 163 lb 11/16/2011 Lawyer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/23/2009 39 Male 112 lb 11/22/2011 Physician Japan
Primary
Secondary
Concomitant
Bronchitis Hospitalization 10/16/2006 48 Female 132 lb 11/23/2011 Physician Japan
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Lymphocyte Stimulation Test Positive Death 6/8/2011 47 Male 12/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Nervousness Hospitalization 12/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Other Serious 4/22/2010 13 Male 90 lb 1/9/2012 Physician Japan
Primary
Concomitant
Death Death 11/6/2011 81 Female 1/17/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Abdominal Distension Other Serious 6/1/2007 41 Female 218 lb 1/26/2012 Lawyer United States
Primary
Secondary
Concomitant
Epistaxis 10/12/2011 60 Female 245 lb 12/10/2011 United States
Primary
Concomitant
Immunosuppressant Drug Level Increased Other Serious 2/10/2012 Female 17 lb 2/16/2012 Physician Belgium
Primary
Concomitant
Altered State Of Consciousness Other Serious 2/7/2012 50 Female 2/19/2012 Physician Japan
Primary
Concomitant
Rhinorrhoea 11/30/2011 62 Female 210 lb 2/27/2012 Consumer United States
Primary
Concomitant
Nephrogenic Anaemia Hospitalization 4/8/2010 Female 2/27/2012 Consumer China
Primary
Concomitant

Drug Data