Spironolactone combined with Tramadol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperkalaemia Hospitalization 12/2/2005 61 Male Pharmacist United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 7/10/2008 Female 12/31/2008 Physician United Kingdom
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 3/30/2009 United Kingdom
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 7/29/2003 43 Male 249 lb 4/21/2009 United States
Primary
Concomitant
Application Site Burn Other Serious 5/3/2009 59 Female 197 lb 5/13/2009 Consumer United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unevaluable Event Hospitalization 71 Female 7/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 10/13/2006 65 Female 167 lb 8/5/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 71 Female 8/5/2009 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 65 Female 8/12/2009 Physician Colombia
Primary
Concomitant
Vomiting Other Serious 82 Female 9/10/2009 United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 9/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Weight Increased Other Serious 30 Male 9/18/2009 United States
Primary
Concomitant
Septic Shock Hospitalization 12/1/2007 47 10/8/2009 Physician Belgium
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 10/16/2009 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Dehydration Hospitalization 12/10/2008 62 Male 161 lb 11/13/2009 Physician Malaysia
Primary
Concomitant
Dyspepsia Other Serious 7/1/2008 Male 331 lb 11/19/2009 Physician United States
Primary
Concomitant
Dehydration Hospitalization 12/10/2008 62 Male 161 lb 11/24/2009 Physician Malaysia
Primary
Concomitant
Vomiting Other Serious Female 12/14/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 1/1/2009 Female 1/5/2010 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/29/2009 59 Female 230 lb 1/13/2010 Pharmacist United States
Primary
Concomitant
Interacting
Weight Decreased Other Serious 12/1/2003 Male 159 lb 1/19/2010 Physician United States
Primary
Concomitant
Hepatotoxicity Death 9/21/2009 33 Female 1/21/2010 Pharmacist Spain
Primary
Concomitant
Death Death Female 136 lb 1/21/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/13/2010 United States
Primary
Concomitant
Vocal Cord Disorder Hospitalization 57 Female 1/8/2010 United States
Primary
Concomitant
Pulmonary Hypertension Death Female 136 lb 1/27/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 82 Female 1/21/2010 United States
Primary
Concomitant
Rhinorrhoea 1/1/2008 Female 170 lb 1/30/2010 Consumer United States
Primary
Concomitant
Skin Fissures 11/1/2009 Female 175 lb 1/30/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Female 1/22/2010 United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious Female 2/13/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 Male 159 lb 2/15/2010 Physician United States
Primary
Concomitant
Malaise Life Threatening 8/28/2008 85 Female 2/16/2010 Germany
Primary
Secondary
Concomitant
Testicular Swelling Life Threatening 55 Male 4/6/2010 Consumer United States
Primary
Concomitant
Wound Infection Pseudomonas Other Serious 1/23/2006 65 Female 4/7/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 40 Female 181 lb 5/7/2010 Lawyer United States
Primary
Concomitant
Impaired Healing Hospitalization 4/12/2010 60 203 lb 6/2/2010 Physician Netherlands
Primary
Secondary
Concomitant
Weight Increased Other Serious 30 Male 226 lb 6/1/2010 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 49 Female 5/27/2010 United States
Primary
Concomitant
Wheezing Hospitalization 81 Male 6/2/2010 United States
Primary
Concomitant
Stevens-johnson Syndrome Death 4/15/2010 48 Male 6/11/2010 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/24/2009 81 Male 6/16/2010 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 6/21/2010 Other Health Professional Korea, Republic Of
Primary
Concomitant
Pneumonia Hospitalization 6/1/2010 67 Female 7/9/2010 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 7/13/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Insomnia 10/31/2007 60 Male 288 lb 7/17/2010 Consumer United States
Primary
Concomitant
Interacting
Sudden Death Other Serious 7/24/2009 81 Male 7/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/15/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Pyrexia Hospitalization 6/7/2010 73 Female 9/20/2010 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 12/18/2009 68 Female 184 lb 9/28/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Collapse Of Lung Hospitalization 70 Male 157 lb 9/28/2010 Consumer United States
Primary
Concomitant
Small Intestinal Perforation Other Serious 8/1/2010 68 Female 286 lb 9/28/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 9/1/2010 62 Female 150 lb 10/5/2010 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 12/10/2008 62 Male 161 lb 10/13/2010 Physician Malaysia
Primary
Concomitant
Shock Death Female 10/21/2010 Physician United States
Primary
Concomitant
Wheezing Hospitalization 9/28/2005 74 Female 11/11/2010 United States
Primary
Concomitant
Transplant Rejection Hospitalization 11/22/2010 66 Female 201 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 11/2/2010 82 Male 168 lb 12/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2010 42 Female 12/29/2010 Physician United States
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 10/10/2010 72 Female 1/20/2011 Physician United States
Primary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 75 Female 1/26/2011 Consumer United States
Primary
Concomitant
Cardiac Operation Other Serious 65 Female 179 lb 3/8/2011 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 74 Female 179 lb 3/8/2011 Consumer United States
Primary
Secondary
Concomitant
Scoliosis Disability 12/1/2003 79 Male 159 lb 3/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Death 3/8/2011 76 Female 3/29/2011 Other Health Professional United States
Primary
Concomitant
Dermatitis Contact Hospitalization 1/23/2006 65 Female 3/30/2011 Lawyer United States
Primary
Concomitant
Intervertebral Disc Disorder Hospitalization 1/1/2010 42 Female 4/15/2011 Consumer United States
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/22/2009 67 Female 99 lb 4/26/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Food Poisoning Hospitalization 1/1/2007 49 Female 4/26/2011 Consumer Netherlands
Primary
Concomitant
Cellulitis Staphylococcal Hospitalization 6/1/2006 47 Female 153 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 5/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 6/10/2003 56 Female 119 lb 8/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 11/22/2010 72 Female 124 lb 9/16/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Hyponatraemia Other Serious 9/28/2011 Other Health Professional France
Primary
Secondary
Cold Sweat Hospitalization 8/9/2010 52 Male 233 lb 1/3/2012 Physician United States
Primary
Secondary
Concomitant
Feeling Abnormal Male 173 lb 1/9/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal Male 174 lb 2/10/2012 Physician United States
Primary
Concomitant
Bradycardia Hospitalization 8/9/2010 52 Male 233 lb 2/20/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 2/1/2012 31 Female 168 lb 4/19/2012 Physician United States
Primary
Concomitant
Chronic Hepatic Failure Disability 3/1/2012 46 Female 184 lb 5/2/2012 Consumer United States
Primary
Concomitant
Chronic Hepatic Failure Other Serious 3/1/2012 46 Female 184 lb 6/1/2012 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Disability 3/1/2012 46 Female 184 lb 6/11/2012 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Death 1/20/2011 66 Male 1/15/2013 Pharmacist Us
Primary
Concomitant
Renal Failure Acute Hospitalization 8/18/2011 55 Male 187 lb 6/7/2013 Pharmacist Us
Primary
Concomitant
Treatment Noncompliance Other Serious NotSpecified 1/8/2013 Pharmacist Us
Primary
Secondary
Concomitant
Interacting
Renal Failure Chronic Other Serious 8/30/2009 57 Female 11/15/2012 Physician Us
Primary
Concomitant
Weight Increased Hospitalization 1/16/2012 57 Female 230 lb 10/11/2012 Pharmacist Us
Primary
Concomitant
Wound Infection Death 1/25/2012 73 Female 12/3/2012 Consumer Country Not Specified
Primary
Concomitant
Weight Increased Other Serious 4/15/2011 57 Male 272 lb 11/1/2012 Us
Primary
Secondary
Vomiting Hospitalization 6/16/2012 50 Female 160 lb 9/4/2012 Physician Us
Primary
Secondary
Concomitant
Vasculitis Other Serious 5/8/2012 79 Female 122 lb 10/17/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 10/24/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 6/2/2012 79 Female 122 lb 6/20/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 6/7/2010 31 Female 350 lb 1/14/2013 Consumer Us
Primary
Secondary
Concomitant
Prostate Cancer Hospitalization 74 Male 9/17/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 7/6/2012 78 Male 231 lb 9/7/2012 Physician De
Primary
Concomitant
Sleep Disorder Due To A General Medical Condition Hospitalization 2/12/2012 80 Female 9/12/2012 Consumer Us
Primary
Concomitant
Death Death 2012 Male 180 lb 10/29/2012 Physician Us
Primary
Concomitant
Haemoglobin Decreased Hospitalization 9/25/2012 81 Female 101 lb 10/17/2012 Physician Nz
Primary
Concomitant
Thermal Burn Other Serious 9/4/2012 49 Female 9/4/2012 Consumer Us
Primary
Concomitant
Toxic Skin Eruption Hospitalization 4/1/2012 39 Male 10/18/2012 Physician Fr
Primary
Secondary
Concomitant
Pain In Extremity 10/2012 46 Female 130 lb 10/18/2012 Consumer Us
Primary
Concomitant
Vomiting Hospitalization 9/6/2012 61 Female 10/24/2012 Physician Us
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/5/2010 66 Male 106 lb 2/4/2013 Physician Be
Primary
Concomitant
Wound Other Serious 2012 59 Female 1/28/2013 Consumer Us
Primary
Concomitant
Wound Hospitalization 11/12/2012 59 Female 12/21/2012 Physician Us
Primary
Concomitant
Renal Failure Acute Other Serious 10/26/2012 58 Female 3/12/2013 Physician Fr
Primary
Secondary
Concomitant
Hip Fracture Hospitalization Female 2/5/2013 Physician Us
Primary
Concomitant
Weight Decreased Other Serious 10/29/2012 63 Female 224 lb 11/20/2012 Pharmacist Us
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/8/2012 78 Male 248 lb 9/12/2012 Pharmacist Us
Primary
Secondary
Concomitant
Vomiting Other Serious 11/28/2011 71 Female 12/17/2012 Consumer Us
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Weight Decreased Other Serious Female 140 lb 2/8/2013 Physician Us
Primary
Concomitant
Device Related Infection Hospitalization 12/10/2012 82 Female 155 lb 2/12/2013 Physician Us
Primary
Concomitant
Injection Site Pain 10/2011 61 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Erythema 11/4/2012 36 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Hypersensitivity 12/13/2012 45 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Vena Cava Thrombosis Other Serious 10/14/2009 25 Female 170 lb 5/16/2013 Lawyer Us
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration 7/9/2012 67 Female 2/11/2013 Us
Primary
Concomitant
Wrist Fracture Hospitalization 1/16/2013 62 Female 2/26/2013 Consumer Us
Primary
Concomitant
Urticaria Hospitalization 2010 Female 250 lb 3/5/2013 Consumer Country Not Specified
Primary
Concomitant
Oedema Peripheral Hospitalization 2/25/2013 79 Male 149 lb 6/5/2013 Physician Br
Primary
Secondary
Concomitant
Fatigue 65 Male 3/8/2013 Other Health Professional Us
Primary
Concomitant
Pulmonary Embolism Hospitalization 10/2012 45 Female 3/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/2013 64 Female 163 lb 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 11/5/2010 66 Male 106 lb 5/14/2013 Physician Be
Primary
Concomitant
Stress Cardiomyopathy Life Threatening 2/28/2013 57 Female 178 lb 4/10/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 8/30/2009 56 Female 4/26/2013 Lawyer Us
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/23/2012 75 Male 10/29/2012 Physician Se
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 5/20/2013 Consumer Country Not Specified
Primary
Concomitant
Pancreatitis Chronic Hospitalization 2/5/2013 73 Male 243 lb 4/16/2013 Physician Us
Primary
Secondary
Concomitant
Drug Ineffective 4/2013 83 Female 198 lb 4/24/2013 Consumer Us
Primary
Concomitant
Carotid Artery Stenosis Hospitalization 7/7/2011 46 Male 4/19/2013 Physician De
Primary
Secondary
Concomitant

Drug Data