Spironolactone combined with Torsemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 11/1/2002 79 Female 115 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Haemoptysis Life Threatening 3/3/2003 33 Female 1/24/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 11/23/2002 79 Female 115 lb 1/24/2006 Physician United States
Primary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 5/25/2005 Female 2/24/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/8/2004 Female 3/3/2006 Physician Germany
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 10/2/2005 84 Male 2/2/2006 Pharmacist United States
Primary
Concomitant
Liver Disorder Hospitalization 10/19/2005 Male 130 lb 3/16/2006 Switzerland
Primary
Concomitant
Vomiting Hospitalization 9/8/2004 Female 3/28/2006 Physician Germany
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/28/2005 65 Female 3/31/2006 Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2005 Male 130 lb 4/13/2006 Switzerland
Primary
Concomitant
Weight Increased Other Serious 2/1/1999 57 4/1/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 12/13/2005 56 Male 220 lb 4/24/2006 Germany
Primary
Concomitant
Sputum Discoloured Life Threatening 3/3/2003 33 Female 5/5/2006 Physician Japan
Primary
Secondary
Concomitant
Melanocytic Naevus Hospitalization 10/19/2005 Male 130 lb 5/11/2006 Switzerland
Primary
Concomitant
Hyperammonaemia Hospitalization 1/15/2005 95 Female 5/16/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/15/2005 96 Female 5/17/2006 Physician Switzerland
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/15/2005 96 Female 5/17/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Throat Irritation Hospitalization Male 5/24/2006 Consumer United States
Primary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 8/17/2005 33 Female 97 lb 5/31/2006 Japan
Primary
Concomitant
Weight Increased Hospitalization 1/15/2005 96 Female 5/31/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 10/1/2004 Female 139 lb 7/7/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Flatulence 1/1/2006 Female 130 lb 8/4/2006 Physician United States
Primary
Concomitant
Mitral Valve Sclerosis Other Serious 5/9/2005 54 Male 154 lb 8/10/2006 Physician Germany
Primary
Concomitant
Haemolysis Other Serious 11/9/2005 50 Female 169 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Liver Disorder Hospitalization 10/17/2005 Male 130 lb 8/25/2006 Switzerland
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 8/18/2006 Pharmacist United States
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 5/7/2004 Male 121 lb 9/22/2006 Germany
Primary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/3/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2004 Male 230 lb 10/5/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2005 Male 88 lb 10/7/2006 Physician Germany
Primary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 7/16/2006 Female 227 lb 11/14/2006 Physician Germany
Primary
Concomitant
Retroperitoneal Haemorrhage Death 6/2/2006 60 Male 194 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
Blood Urea Increased Hospitalization 5/7/2004 Male 121 lb 12/18/2006 Germany
Primary
Concomitant
Superinfection Other Serious 1/1/2006 79 Female 154 lb 12/21/2006 Physician Germany
Primary
Concomitant
Renal Failure Death 11/30/2006 78 Male 12/15/2006 Physician Germany
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 9/1/2006 80 Male 12/28/2006 Consumer United States
Primary
Concomitant
Right Ventricular Failure Death 11/30/2006 Male 1/9/2007 Physician Germany
Primary
Concomitant
Pulmonary Hypertension 6/1/2005 34 Female 165 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Hallucination Hospitalization 12/1/2005 71 Male 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Disorder Hospitalization 12/1/2006 72 Female 1/19/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2006 Male 169 lb 2/14/2007 Other Health Professional United States
Primary
Concomitant
Kidney Infection 8/1/2006 56 Female 10/16/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/21/2007 Male 187 lb 2/27/2007
Primary
Secondary
Concomitant
Weight Increased Hospitalization 76 Female 3/14/2007 Consumer United States
Primary
Concomitant
Pericardial Effusion Other Serious Female 3/20/2007 Consumer Germany
Primary
Concomitant
Intestinal Ischaemia Hospitalization 1/20/2007 82 Male 3/19/2007 Germany
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/21/2007 Male 187 lb 3/23/2007
Primary
Secondary
Haematemesis Other Serious 5/2/2006 Male 3/27/2007 Germany
Primary
Concomitant
Vomiting Required Intervention 6/23/2005 36 Female 90 lb 3/20/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2006 Male 169 lb 3/30/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 1/21/2007 Male 187 lb 4/4/2007
Primary
Secondary
Haematemesis Other Serious 5/2/2006 Male 157 lb 4/4/2007 Germany
Primary
Concomitant
Syncope Required Intervention 76 Male 4/4/2007 Germany
Primary
Secondary
Concomitant
Hypotonia Hospitalization 5/15/2006 70 Male 5/1/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious Female 5/8/2007 Consumer Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 8/1/2006 Male 169 lb 5/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Required Intervention 6/23/2005 36 Female 90 lb 6/4/2007 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/1/2007 Female 206 lb 6/19/2007 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 3/20/2007 70 Female 147 lb 6/13/2007 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Other Serious 4/1/2007 Female 7/6/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 5/12/2007 63 Female 255 lb 7/3/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 4/19/2007 Male 7/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Nausea Hospitalization 7/1/2007 Male 8/24/2007 Other Health Professional Germany
Primary
Concomitant
Musculoskeletal Pain 8/3/2006 56 Female 7/11/2007 Physician United States
Primary
Concomitant
Seroma Hospitalization 1/9/2006 Female 150 lb 9/5/2007 Physician Switzerland
Primary
Concomitant
Renal Failure Hospitalization 1/21/2007 Male 187 lb 9/21/2007
Primary
Secondary
Rhabdomyolysis Required Intervention 62 Male 9/21/2007 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 9/1/2006 62 Male 10/1/2007 Physician Germany
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 10/17/2005 Male 130 lb 10/10/2007 Switzerland
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/1/2005 76 Female 10/23/2007 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/8/2007 Other Health Professional United States
Primary
Concomitant
Death Death 10/5/2007 Female 154 lb 11/8/2007 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/12/2007 Other Health Professional United States
Primary
Concomitant
Nocturnal Dyspnoea 8/22/2007 69 Male 11/14/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/25/2005 76 Female 11/29/2007 Other Health Professional United States
Primary
Concomitant
Seroma Hospitalization 1/9/2006 Female 150 lb 12/3/2007 Physician Switzerland
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 73 Male 12/18/2007 Physician Switzerland
Primary
Secondary
Concomitant
Loss Of Libido 1/1/2003 59 Female 1/17/2008 Consumer United States
Primary
Concomitant
Bradyarrhythmia Hospitalization 12/5/2007 61 Female 154 lb 1/28/2008 Physician Lithuania
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/13/2004 77 Male 1/29/2008 Physician Germany
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 62 Male 1/21/2008 Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/5/2008 Germany
Primary
Secondary
Concomitant
Sudden Death Death 1/11/2008 49 Male 1/23/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/11/2007 56 Female 176 lb 2/12/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/1/2003 58 Female 2/13/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 Male 2/13/2008 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/11/2007 56 Female 176 lb 2/14/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/19/2008 Physician Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/21/2008 Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/22/2008 Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/13/2004 78 Male 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 77 Male 2/25/2008 Germany
Primary
Secondary
Concomitant
Melaena Hospitalization 9/19/2007 61 Male 2/26/2008 Physician Switzerland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/13/2004 81 Male 2/29/2008 Other Health Professional Germany
Primary
Secondary
Sudden Death Death 1/11/2008 49 Male 3/3/2008 Physician Germany
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 1/1/2006 64 Male 3/20/2008 Consumer United States
Primary
Concomitant
Rash Disability 12/27/2007 Male 296 lb 3/25/2008 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/4/2008 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 1/1/2004 79 Female 4/11/2008 Physician United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/18/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/23/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Wrong Technique In Drug Usage Process Life Threatening 1/1/2006 79 Female 150 lb 5/2/2008 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 10/5/2007 Female 154 lb 6/5/2008 Physician United Kingdom
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 5/30/2008 38 Female 176 lb 7/2/2008 Other Health Professional Germany
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/3/2008 Physician Japan
Primary
Concomitant
Myocardial Infarction Life Threatening 5/20/2008 Female 7/3/2008 Physician Germany
Primary
Concomitant
Blood Urea Increased Hospitalization 3/19/2008 Female 174 lb 7/16/2008 Physician Germany
Primary
Secondary
Vomiting Other Serious 4/21/2008 66 Male 155 lb 7/10/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/18/2008 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 12/7/2006 42 Female 7/23/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/2/2008 50 Female 7/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Other Serious 6/15/2008 Male 172 lb 8/1/2008 Physician Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 5/20/2008 Female 7/30/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 7/20/2008 41 Female 8/4/2008 Germany
Primary
Secondary
Disease Progression Other Serious 3/19/2008 Female 174 lb 8/7/2008 Physician Germany
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 3/15/2008 8/12/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Fluctuation 6/8/2007 43 Female 142 lb 8/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Death 3/31/2008 77 Female 8/20/2008 United States
Primary
Concomitant
Flushing 5/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 8/27/2008 United States
Primary
Concomitant
Tremor Other Serious 9/1/2007 Female 9/3/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Tremor Other Serious 9/1/2007 Female 9/4/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Injection Site Pain Other Serious 10/29/2007 74 Male 9/5/2008 Japan
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/21/2008 66 Male 155 lb 9/10/2008 United States
Primary
Concomitant
Tremor Other Serious 9/3/2007 Female 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Skin Erosion Other Serious 1/1/2006 Female 9/23/2008 Consumer Germany
Primary
Concomitant
Injection Site Pain Other Serious 10/29/2007 74 Male 9/26/2008 Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2008 Male 185 lb 9/26/2008 United States
Primary
Concomitant
Tremor Other Serious 9/3/2007 Female 10/13/2008 Physician Japan
Primary
Secondary
Concomitant
Interacting
Cardiac Failure Hospitalization 5/14/2008 56 Female 10/14/2008 Physician Japan
Primary
Concomitant
Skin Erosion Other Serious 1/1/2006 Female 10/17/2008 Physician Germany
Primary
Concomitant
Hypotonia Hospitalization 5/15/2006 Male 11/5/2008 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Other Serious 3/1/2008 Female 154 lb 11/7/2008 Germany
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 10/26/2006 70 Male 11/5/2008 Physician Germany
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 10/6/2008 38 Male 11/11/2008 Physician Germany
Primary
Concomitant
Status Epilepticus Life Threatening 9/1/2008 Female 11/16/2008 Physician Germany
Primary
Concomitant
Torsade De Pointes Other Serious 8/25/2008 Male 11/25/2008 Germany
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/10/2008 Other Health Professional United States
Primary
Concomitant
Orthostatic Hypotension 54 Male 205 lb 12/17/2008 United States
Primary
Concomitant

Drug Data