Spironolactone combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gynaecomastia Other Serious 1/1/2001 65 Male 226 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Haemarthrosis Hospitalization 11/1/2005 59 Female 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Interacting
Hyperthermia Other Serious 1/1/2001 65 Male 226 lb 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Death 7/18/2005 Female 102 lb 1/23/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 8/24/2005 71 Female 1/25/2006 Other Health Professional United States
Primary
Secondary
Viral Infection Hospitalization 12/19/2005 Female 2/7/2006 Consumer United States
Primary
Concomitant
Vein Disorder Other Serious 5/9/2001 67 Female 170 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 1/13/2004 81 Female 2/10/2005 Pharmacist United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2003 57 Male 201 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 63 Male 230 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 9/5/2003 81 Female 2/27/2006 Lawyer United States
Primary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 43 Female 181 lb 2/27/2006 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 1/1/2003 57 Male 201 lb 2/27/2006 Physician United States
Primary
Concomitant
Dry Mouth 12/7/2005 83 Male 2/27/2006 Consumer United States
Primary
Concomitant
Rash Pruritic Other Serious 4/8/2005 42 Female 2/28/2006 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 10/24/2005 74 Female 195 lb 1/20/2006 Physician United States
Primary
Concomitant
Rash Other Serious 49 Female 237 lb 2/27/2006 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 7/12/2005 46 Female 99 lb 1/17/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2003 43 Female 181 lb 3/24/2006 Physician United States
Primary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 Consumer United States
Primary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2003 Female 3/27/2006 United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 70 Male 202 lb 4/19/2006 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 1/1/1999 55 Female 192 lb 4/19/2006 Physician United States
Primary
Concomitant
Road Traffic Accident Other Serious 3/20/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 4/25/2006 United States
Primary
Concomitant
Drug Interaction Other Serious 6/24/2005 68 Female 187 lb 5/9/2006 Consumer United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 52 Female 100 lb 1/16/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 1/1/2005 Male 5/24/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 5/11/2005 90 Male 205 lb 5/30/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 3/17/2006 73 Female 210 lb 4/20/2006 United States
Primary
Concomitant
Vomiting Other Serious 2/1/2006 66 Female 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Photosensitivity Reaction 1/1/2004 74 Male 3/14/2006 United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 10/11/2005 78 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/29/2005 68 Female 196 lb 7/6/2006 United States
Primary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Renal Disorder 1/1/2004 80 Male 7/21/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Liver Disorder Other Serious 1/1/2005 50 Female 7/20/2006 Consumer United States
Primary
Concomitant
Tooth Infection Other Serious 6/1/2006 59 Female 8/4/2006 Physician United States
Primary
Concomitant
Haemoptysis 1/4/2006 83 Female 5/24/2006 Other Health Professional United States
Primary
Concomitant
Wheezing Hospitalization 1/1/1994 Male 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2005 50 Female 7/28/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 71 Female 155 lb 8/22/2006 United States
Primary
Concomitant
Hypoaesthesia Other Serious 3/17/2006 73 Female 210 lb 7/19/2006 United States
Primary
Concomitant
Fluid Retention Other Serious 1/1/2006 70 Female 192 lb 7/19/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 8/18/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2006 Female 88 lb 9/1/2006 Physician United States
Primary
Concomitant
Somnolence 2/11/2006 86 Male 9/6/2006 Consumer United States
Primary
Concomitant
Weight Decreased Female 7/19/2006 Consumer United States
Primary
Concomitant
Syncope Required Intervention 8/19/2006 73 Male 248 lb 10/3/2006 Pharmacist United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 10/16/2006 Consumer United States
Primary
Concomitant
Dysphonia 1/1/2005 72 Female 10/30/2006 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 42 Female 10/30/2006 Consumer United States
Primary
Concomitant
Tremor Hospitalization 9/1/2006 79 Female 200 lb 10/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 251 lb 11/2/2006 Physician United States
Primary
Concomitant
Vomiting Projectile Other Serious 10/20/2006 81 Female 172 lb 11/9/2006 Pharmacist United States
Primary
Concomitant
Weight Fluctuation Hospitalization 9/9/2006 67 Male 255 lb 11/15/2006 Physician United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2004 64 Female 12/12/2006 United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Haemorrhage Urinary Tract Other Serious 11/6/2006 Female 150 lb 12/20/2006 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 1/1/2004 64 Female 12/21/2006 United States
Primary
Secondary
Concomitant
Dry Mouth 12/7/2005 83 Male 12/28/2006 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2006 75 Female 10/19/2006 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Death 72 Female 1/23/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 10/1/2005 76 Female 1/15/2007 Other Health Professional United States
Primary
Concomitant
Refractory Anaemia Hospitalization 7/26/2006 Male 157 lb 1/26/2007 Other Health Professional Canada
Primary
Concomitant
Feeling Jittery 9/9/2006 76 Female 156 lb 10/16/2006 Consumer United States
Primary
Concomitant
Tinnitus Other Serious 7/12/2006 75 Female 160 lb 8/17/2006 United States
Primary
Concomitant
Refractory Anaemia Hospitalization 7/26/2006 Male 157 lb 2/9/2007 Other Health Professional Canada
Primary
Concomitant
Weight Increased Required Intervention 11/28/2005 68 Female 2/9/2007 Physician United States
Primary
Concomitant
Weight Decreased 5/1/2006 66 Female 212 lb 10/16/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 10/1/2005 76 Female 2/9/2007 Other Health Professional United States
Primary
Concomitant
Nasal Septum Perforation Death 2/14/2006 52 Female 130 lb 2/9/2007 Physician United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2006 63 Female 205 lb 2/16/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2006 Female 156 lb 3/2/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 66 Female 3/7/2007 Consumer United States
Primary
Concomitant
Sepsis Death 83 Female 181 lb 3/12/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 75 Female 135 lb 4/8/2005 United States
Primary
Concomitant
Hyperglycaemia Other Serious 75 Female 135 lb 4/8/2005 United States
Primary
Concomitant
Weight Increased Hospitalization 76 Female 3/14/2007 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious Female 4/16/2004 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 50 Female 100 lb 3/16/2007 Consumer United States
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 11/1/2006 68 Female 135 lb 3/9/2007 Physician Canada
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 8/9/2004 46 Female 173 lb 11/27/2006 United States
Primary
Concomitant
Tooth Disorder Other Serious 7/2/1999 99 Female 3/23/2007 Physician United States
Primary
Concomitant
Nasal Septum Perforation Death 2/14/2006 52 Female 130 lb 3/22/2007 Physician United States
Primary
Concomitant
Peripheral Coldness 10/11/2006 88 Female 11/7/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/17/2007 68 Female 130 lb 3/30/2007 Consumer United States
Primary
Concomitant
Refractory Anaemia Other Serious 7/26/2006 Male 157 lb 4/3/2007 Physician Canada
Primary
Concomitant
Urticaria 9/1/2006 28 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Insomnia 12/1/2006 85 Male 155 lb 1/12/2007 Consumer United States
Primary
Concomitant
Nasal Septum Perforation Death 2/14/2006 Female 130 lb 4/9/2007 Physician United States
Primary
Concomitant
Death Death 4/1/2007 48 Female 436 lb 4/6/2007 Physician United States
Primary
Concomitant
Walking Aid User Other Serious 10/1/2005 76 Female 4/2/2007 Other Health Professional United States
Primary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 4/21/2007 United States
Primary
Concomitant
Therapeutic Response Decreased 12/1/2006 77 Female 148 lb 4/24/2007 Consumer United States
Primary
Concomitant
Telangiectasia Hospitalization 4/27/2007 Physician Canada
Primary
Concomitant
Fatigue Other Serious 1/1/2005 75 Female 5/8/2007 United States
Primary
Concomitant
Sepsis Death 83 Female 181 lb 5/9/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased 11/5/2006 71 Female 2/16/2007 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 1/24/2007 73 Male 201 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Skin Discolouration Other Serious 5/8/2007 52 Female 5/22/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 3/17/2007 68 Female 96 lb 5/23/2007 Consumer United States
Primary
Concomitant
Death Death 4/3/2007 48 Female 436 lb 5/24/2007 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased 12/12/2006 70 Female 5/17/2007 United States
Primary
Concomitant
Irritability 76 Female 181 lb 6/22/2007 Consumer United States
Primary
Concomitant
Myalgia Disability 4/1/2007 81 Female 6/29/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 7/5/2007 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 81 Female 129 lb 7/5/2007 Consumer United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 7/13/2007 Physician United States
Primary
Concomitant
Osteoarthritis Other Serious 1/1/2004 68 Female 7/16/2007 United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 7/17/2007 Physician Canada
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 7/27/2007 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 5/30/2007 69 Female 7/25/2007 Physician United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/2/2007 United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 6/1/2005 45 Female 177 lb 6/8/2007 Other Health Professional United States
Primary
Concomitant
Keratitis Required Intervention 6/25/2007 48 Female 130 lb 8/6/2007 Other Health Professional United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/10/2007 United States
Primary
Concomitant
Syncope Hospitalization 5/30/2007 69 Female 8/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 6/1/2007 60 Female 8/14/2007 United States
Primary
Concomitant
Angioedema Other Serious 7/1/2007 Female 8/20/2007 Physician Canada
Primary
Concomitant
Weight Decreased 5/6/2006 66 Female 212 lb 7/11/2007 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 8/14/2007 Female 170 lb 8/29/2007 Physician United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 8/7/2007 63 Male 8/29/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 6/24/2007 46 Female 181 lb 8/29/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/16/2007 76 Female 9/10/2007 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 11/17/2000 35 Female 216 lb 9/18/2007 Other Health Professional United States
Primary
Concomitant
Vomiting 8/20/2007 Female 9/18/2007 Consumer United States
Primary
Concomitant
Hepatic Steatosis 12/1/2006 70 Female 8/16/2007 Other Health Professional United States
Primary
Concomitant
Vomiting 8/20/2007 Female 9/28/2007 Consumer United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 5/26/2007 83 Female 188 lb 10/1/2007 United States
Primary
Concomitant
Eye Operation Other Serious 9/1/2007 61 Female 10/8/2007 Consumer Canada
Primary
Concomitant
Interacting
Abdominal Pain Hospitalization 8/14/2007 Female 170 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction 12/1/2004 84 Female 10/25/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 6/1/2006 42 Female 10/25/2007 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 7/18/2007 75 Female 184 lb 9/24/2007 Other Health Professional United States
Primary
Concomitant
Haemorrhagic Infarction Hospitalization 5/26/2007 83 Female 188 lb 11/8/2007 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2005 Male 242 lb 11/9/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 11/7/2007 Female 170 lb 11/21/2007 Other Health Professional United States
Primary
Concomitant
Malaise 8/3/2007 75 Female 12/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/31/2007 Female 80 lb 12/5/2007 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Other Serious 11/1/2007 Female 131 lb 12/7/2007 Consumer United States
Primary
Concomitant
Urine Odour Abnormal Other Serious 11/1/2007 Female 153 lb 12/19/2007 Consumer United States
Primary
Concomitant
Palpitations Hospitalization 6/18/2007 64 Female 171 lb 12/19/2007 Physician United States
Primary
Concomitant
Urticaria Other Serious 7/2/1996 89 Female 148 lb 1/18/2008 Physician United States
Primary
Concomitant
Skin Exfoliation 7/2/2007 77 Male 11/2/2007 Other Health Professional United States
Primary
Concomitant
Malaise 8/3/2007 75 Female 1/22/2008 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/31/2007 Female 80 lb 1/23/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2007 62 Female 147 lb 1/18/2008 Physician United States
Primary
Concomitant

Drug Data