Spiriva combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumonia Primary Atypical Life Threatening 2/17/2006 79 Male 2/27/2006 Physician Japan
Primary
Concomitant
Sputum Discoloured 1/1/2005 63 Female 211 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Other Serious 75 Female 180 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Dyspnoea 1/26/2006 70 Female 2/21/2006 United States
Primary
Concomitant
Sputum Discoloured 11/29/2005 Male 2/21/2006 United States
Primary
Concomitant
Drug Ineffective 9/1/2005 Female 2/21/2006 United States
Primary
Concomitant
Lip Dry 11/28/2005 79 Female 2/21/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/13/2006 83 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 2/1/2006 76 Female 165 lb 4/20/2006 United States
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 5/19/2006 United States
Primary
Concomitant
Lip Dry 11/28/2005 79 Female 5/19/2006 United States
Primary
Secondary
Concomitant
Drug Ineffective 4/10/2006 67 Male 5/19/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 54 Female 262 lb 7/25/2006 United States
Primary
Concomitant
Hepatotoxicity Other Serious 4/16/2006 66 Male 203 lb 8/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rash Generalised Required Intervention 7/24/2006 85 Male 285 lb 8/10/2006 Other Health Professional United States
Primary
Concomitant
Lip Pain 71 Female 126 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/1993 Male 240 lb 9/1/2006 United States
Primary
Secondary
Concomitant
Knee Arthroplasty Hospitalization 8/22/2006 Male 9/14/2006 Consumer United States
Primary
Concomitant
Sudden Death Death 4/5/2005 Male 9/28/2006 Physician United Kingdom
Primary
Secondary
Swelling Face Other Serious 9/14/2006 65 Male 10/11/2006 Consumer United Kingdom
Primary
Concomitant
Death Death 67 Female 162 lb 1/30/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 7/1/2006 79 Male 10/10/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/1/1993 Male 240 lb 10/10/2006 Physician United States
Primary
Secondary
Concomitant
Dyspnoea 6/27/2006 76 Female 8/22/2006 United States
Primary
Concomitant
Dyspnoea 6/12/2006 Male 8/22/2006 United States
Primary
Concomitant
Pollakiuria 6/1/2006 Male 8/22/2006 United States
Primary
Concomitant
Drug Ineffective 4/10/2006 67 Male 8/22/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 8/22/2006 United States
Primary
Concomitant
Dyspnoea 60 Female 8/22/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/1/2005 81 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 8/22/2006 Male 11/7/2006 Consumer United States
Primary
Concomitant
Wound Infection Hospitalization 12/1/2005 81 Female 11/1/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/1/2006 58 Male 188 lb 11/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 4/12/2006 88 Female 169 lb 11/27/2006 Physician United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 11/6/2006 84 Male 12/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chest Pain Other Serious 10/10/2006 Male 130 lb 1/2/2007 Physician Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 4/12/2006 88 Female 169 lb 12/27/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased 1/1/2006 75 Female 10/19/2006 Pharmacist United States
Primary
Concomitant
Angina Pectoris Life Threatening 10/10/2006 Male 130 lb 1/25/2007 Physician Japan
Primary
Concomitant
Drug Ineffective 82 Female 11/21/2006 United States
Primary
Concomitant
Dyspnoea 60 Female 11/21/2006 United States
Primary
Concomitant
Dyspnoea 6/27/2006 76 Female 11/21/2006 United States
Primary
Concomitant
Drug Ineffective 6/1/2006 Male 11/21/2006 United States
Primary
Concomitant
Dysgeusia Male 11/21/2006 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 11/1/2006 42 Female 3/12/2007 Physician United States
Primary
Secondary
Concomitant
Rectal Prolapse Hospitalization 1/1/2006 79 Female 3/26/2007 Consumer United States
Primary
Concomitant
Sputum Retention Other Serious 3/18/2007 Female 200 lb 3/30/2007 Consumer United States
Primary
Concomitant
Candidiasis Other Serious 3/1/2007 Male 250 lb 3/30/2007 Consumer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 11/1/2006 42 Female 5/7/2007 Physician United States
Primary
Secondary
Concomitant
Urine Flow Decreased Other Serious 1/1/2007 65 Male 5/17/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 82 Female 2/22/2007 United States
Primary
Concomitant
Vision Blurred 12/1/2006 Male 2/22/2007 United States
Primary
Concomitant
Vocal Cord Disorder 6/1/2005 79 Female 2/22/2007 United States
Primary
Concomitant
Urine Flow Decreased Other Serious 1/1/2007 65 Male 6/7/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 6/13/2007 64 Female 6/28/2007 Physician
Primary
Concomitant
Neuropathy Peripheral Other Serious 11/1/2006 42 Female 6/26/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 78 Male 7/4/2007 Physician United States
Primary
Concomitant
Sepsis Hospitalization 4/15/2007 76 Female 146 lb 7/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 1/1/2007 68 Male 148 lb 7/16/2007 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 1/1/2007 68 Male 148 lb 7/17/2007 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 3/18/2007 Female 200 lb 7/18/2007 Consumer United States
Primary
Concomitant
Presyncope Other Serious 4/24/2007 70 Male 7/13/2007 Physician Sweden
Primary
Concomitant
Diarrhoea Other Serious 1/1/2006 74 Female 179 lb 7/9/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 8/13/2007 Physician Australia
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/4/2007 Male 8/23/2007 Physician Australia
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/17/2007 Male 128 lb 8/27/2007 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 7/31/2007 67 Male 225 lb 8/28/2007 United Kingdom
Primary
Concomitant
Speech Disorder 8/16/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/31/2007 67 Male 225 lb 8/31/2007 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/6/2007 67 Male 225 lb 9/7/2007 United Kingdom
Primary
Concomitant
Vision Blurred 8/1/2006 Female 9/18/2007 Consumer United States
Primary
Concomitant
Prostate Infection 1/1/2007 Male 9/24/2007 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 4/12/2006 88 Female 355 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/11/2007 53 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Disorder 5/1/2007 Male 10/12/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 11/23/2006 83 Female 10/25/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 2/24/2006 76 Female 175 lb 10/23/2007 Other Health Professional United States
Primary
Concomitant
Prostate Infection 1/1/2007 Male 10/30/2007 Consumer United States
Primary
Concomitant
Vision Blurred 8/1/2006 Female 11/6/2007 Physician United States
Primary
Concomitant
Balance Disorder Other Serious Male 11/9/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/12/2007 United States
Primary
Concomitant
Sinus Disorder 5/1/2007 Male 11/14/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/16/2007 United States
Primary
Concomitant
Post Procedural Infection Other Serious 12/14/2005 Male 131 lb 11/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/27/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 210 lb 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 11/30/2007 United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/5/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/7/2007 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 12/10/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/14/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 Female 12/17/2007 United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 12/27/2007 United States
Primary
Concomitant
Pulmonary Congestion 11/8/2007 Male 1/2/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection 5/3/2007 71 Female 10/9/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 1/4/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 1/9/2008 United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 1/31/2008 United States
Primary
Concomitant
Pulmonary Congestion 11/8/2007 Male 2/5/2008 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Death 1/1/2006 Male 175 lb 2/6/2008 Physician United States
Primary
Concomitant
Heart Rate Increased 1/20/2008 Male 2/6/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/4/2007 Male 2/11/2008 Physician Australia
Primary
Concomitant
Ill-defined Disorder 6/1/2007 Female 2/12/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Rash 9/14/2007 69 Male 140 lb 10/9/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Life Threatening 1/29/2008 Male 143 lb 2/20/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 2/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Death 10/7/2007 80 Male 132 lb 2/27/2008 Consumer Brazil
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 2/28/2008 United States
Primary
Concomitant
Pancreatitis Hospitalization 1/24/2008 78 Female 108 lb 3/3/2008 Consumer United States
Primary
Concomitant
Heart Rate Increased 1/20/2008 Male 3/4/2008 Consumer United States
Primary
Concomitant
Urine Abnormality 1/1/2007 78 Female 3/4/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/25/2004 Female 122 lb 3/6/2008 United States
Primary
Concomitant
Wheezing Hospitalization Female 231 lb 3/7/2008 Physician United States
Primary
Concomitant
Wheezing 8/12/2007 79 Male 3/10/2008 Consumer United States
Primary
Concomitant
Heart Rate Increased 1/20/2008 Male 3/26/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 136 lb 4/2/2008 Consumer United States
Primary
Concomitant
Tongue Discolouration 1/18/2008 Male 4/8/2008 Consumer United States
Primary
Concomitant
Constipation 11/1/2007 Male 4/10/2008 Consumer United States
Primary
Concomitant
Malaise Female 4/14/2008 Consumer United States
Primary
Concomitant
Convulsion Other Serious 1/5/2007 Male 209 lb 4/15/2008 Consumer United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 4/23/2008 Consumer United States
Primary
Concomitant
Lymphoma Other Serious 68 Female 4/25/2008 Other Health Professional United States
Primary
Concomitant
Rash Generalised 7/1/2007 72 Female 150 lb 4/29/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 Female 136 lb 5/9/2008 United States
Primary
Concomitant
Abasia Other Serious 4/29/2008 Female 137 lb 5/9/2008 United States
Primary
Concomitant
Vomiting Hospitalization 2/29/2008 67 Male 4/30/2008 Physician Norway
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 1/1/2008 Female 98 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Urinary Retention 7/1/2007 Female 5/16/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 4/15/2007 76 Female 146 lb 5/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 1/1/2005 78 Male 241 lb 5/27/2008 Physician Canada
Primary
Concomitant
Vomiting Other Serious 1/1/2008 Female 136 lb 6/6/2008 Consumer United States
Primary
Concomitant
Dry Mouth 1/1/2007 78 Female 6/24/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2004 Female 6/25/2008 Consumer United States
Primary
Concomitant
Cough 4/1/2008 Female 7/1/2008 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 12/1/2007 62 Male 7/3/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention 7/1/2007 Female 7/11/2008 Physician United States
Primary
Concomitant
Dry Mouth 1/1/2007 78 Female 7/28/2008 Consumer United States
Primary
Concomitant
Visual Impairment Hospitalization 2/26/2008 Male 7/29/2008 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Death 11/10/2007 59 Male 143 lb 7/30/2008 Japan
Primary
Concomitant
Urinary Incontinence 1/1/2007 Female 8/12/2008 Consumer United States
Primary
Concomitant
Presyncope Other Serious 4/24/2007 70 Male 8/7/2008 Physician Sweden
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/10/2007 Male 123 lb 8/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 8/6/2008 58 Male 340 lb 8/14/2008 United States
Primary
Concomitant
Haemorrhagic Anaemia Hospitalization 3/11/2008 82 Male 132 lb 7/7/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Infection Other Serious 12/14/2005 Male 131 lb 9/5/2008 Physician United States
Primary
Secondary
Concomitant

Drug Data