Spiriva combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Prostate Cancer Hospitalization 1/1/2000 64 Male 154 lb 4/3/2006 Physician United States
Primary
Concomitant
Weight Decreased 59 Male 300 lb 1/20/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Effect Decreased 1/17/2006 61 Female 2/21/2006 United States
Primary
Concomitant
Drug Effect Decreased 1/17/2006 61 Female 5/19/2006 United States
Primary
Concomitant
Vision Blurred 6/1/2006 Female 8/22/2006 United States
Primary
Concomitant
Oral Candidiasis 47 Female 10/30/2006 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2004 Female 132 lb 3/27/2007 Consumer United States
Primary
Concomitant
Osteoporosis Other Serious 5/1/2002 64 Female 4/11/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 12/8/2006 60 Female 2/22/2007 United States
Primary
Concomitant
Therapeutic Response Delayed Hospitalization Female 140 lb 5/30/2007 Consumer United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Swelling Hospitalization 2/8/2007 Female 5/30/2007 Physician United States
Primary
Concomitant
Dissociation Other Serious 1/1/2006 Female 250 lb 6/1/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 6/5/2007 Female 273 lb 7/24/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 7/10/2007 25 Female 235 lb 7/20/2007 Consumer United States
Primary
Concomitant
Tremor Hospitalization 1/1/2004 Female 132 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Self Injurious Behaviour Other Serious 8/1/2007 Female 8/28/2007 Other Health Professional United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 2/1/2007 Female 211 lb 8/29/2007 United States
Primary
Concomitant
Humerus Fracture Hospitalization 1/1/2007 83 Female 137 lb 9/27/2007 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 2/1/2007 Female 211 lb 10/10/2007 United States
Primary
Concomitant
Ulcer Other Serious 10/1/2007 Male 220 lb 10/30/2007 Consumer United States
Primary
Secondary
Concomitant
Stress Other Serious 1/1/2002 59 Female 126 lb 11/15/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 196 lb 12/19/2007 Consumer United States
Primary
Secondary
Concomitant
Ulcer Other Serious 10/1/2007 Male 220 lb 12/27/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting 65 Male 10/8/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 196 lb 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 1/10/2008 Consumer United States
Primary
Concomitant
Pathological Gambling 10/1/2004 Female 170 lb 4/7/2008 Consumer United States
Primary
Concomitant
Vertigo Other Serious 54 Male 4/23/2008 Consumer Canada
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/1/2007 77 Female 5/14/2008 Consumer United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious 4/21/2008 50 Female 5/23/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 4/10/2008 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 1/1/2005 Female 141 lb 7/17/2008 Consumer United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 5/1/2007 77 Female 8/4/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/7/2008 Female 8/18/2008 Consumer
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2006 Female 8/18/2008 Consumer United States
Primary
Concomitant
Wound Other Serious 9/19/2008 37 Female 190 lb 10/2/2008 Consumer
Primary
Concomitant
Anaphylactoid Reaction Life Threatening 20 Female 160 lb 10/15/2008 Consumer United States
Primary
Concomitant
Status Asthmaticus Life Threatening 9/14/2007 Female 154 lb 11/4/2008 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 57 Male 240 lb 11/20/2008 United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 Female 138 lb 12/2/2008 Physician United States
Primary
Secondary
Concomitant
Status Asthmaticus Life Threatening 9/14/2007 Female 154 lb 12/3/2008 Consumer United States
Primary
Concomitant
Respiratory Depression Other Serious 5/2/2008 50 Female 386 lb 1/8/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting 1/1/2009 Female 3/31/2009 Consumer
Primary
Concomitant
Throat Irritation 56 Male 154 lb 4/13/2009 Other Health Professional
Primary
Concomitant
Vomiting 1/1/2009 Female 4/16/2009 Consumer
Primary
Concomitant
Throat Irritation 56 Male 154 lb 5/4/2009 Other Health Professional
Primary
Concomitant
Weight Decreased Required Intervention 8/11/2008 Male 172 lb 4/2/2009 Consumer United States
Primary
Concomitant
Vertigo Other Serious 11/8/2007 54 5/13/2009 Physician Canada
Primary
Concomitant
Respiratory Arrest Other Serious 6/23/2004 41 Female 204 lb 6/4/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Death 12/21/2008 45 Female 104 lb 6/8/2009 Pharmacist United States
Primary
Concomitant
Pneumonia 1/1/2008 Female 130 lb 6/11/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2002 32 Female 6/15/2009 United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 55 Female 7/2/2009 Physician United States
Primary
Concomitant
Neck Pain Hospitalization 4/1/2009 Female 7/14/2009 Consumer
Primary
Concomitant
Neck Pain Hospitalization 4/1/2009 Female 7/31/2009 Consumer
Primary
Concomitant
Neck Pain Hospitalization 4/1/2009 Female 8/20/2009 Consumer
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/1/2009 Consumer
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/4/2009 Consumer
Primary
Concomitant
Pneumonia Hospitalization 5/1/2007 Female 9/17/2009 Physician
Primary
Concomitant
Pneumonia 1/1/2008 Female 130 lb 9/18/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 4/22/1996 38 Male 194 lb 9/23/2009 United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 12/7/2008 Female 151 lb 9/29/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred 10/1/2009 Female 11/18/2009 Consumer
Primary
Concomitant
Pneumonia Other Serious 44 Female 1/7/2010 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2008 Female 130 lb 1/30/2010 United States
Primary
Concomitant
Vocal Cord Disorder Disability 3/1/2009 50 Female 2/15/2010 Consumer United States
Primary
Concomitant
Throat Irritation Disability 3/1/2009 50 Female 3/5/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 11/1/2009 Female 121 lb 3/5/2010 Consumer Japan
Primary
Concomitant
Somnolence Hospitalization Female 4/13/2010 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 1/1/2006 48 Female 4/16/2010 Consumer
Primary
Secondary
Concomitant
Toothache 12/1/2009 57 Female 4/19/2010 Consumer
Primary
Concomitant
Throat Irritation Disability 3/1/2009 50 Female 4/19/2010 Other Health Professional United States
Primary
Concomitant
Weight Increased Hospitalization 1/17/2005 40 Female 280 lb 4/21/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/17/2005 40 Female 280 lb 4/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 4/7/2010 62 Male 271 lb 5/5/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Nausea Other Serious 3/18/2010 57 Female 104 lb 4/7/2010 United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 12/14/2004 39 Female 280 lb 5/26/2010 Consumer United States
Concomitant
Pneumonia Hospitalization 62 Female 6/3/2010 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2009 50 Female 158 lb 6/17/2010 Consumer United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 12/14/2004 39 Female 280 lb 6/21/2010 Lawyer United States
Primary
Concomitant
Depression Other Serious 6/1/2010 62 Male 186 lb 7/7/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 51 Female 196 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal 2/20/2007 76 Female 101 lb 7/14/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2009 52 Female 158 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 11/5/2007 64 Male 130 lb 7/17/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/21/2008 51 Female 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Depression Other Serious 6/1/2010 62 Male 186 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 59 Female 157 lb 9/13/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2009 52 Female 158 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 6/1/2010 62 Male 186 lb 9/20/2010 Consumer United States
Primary
Secondary
Concomitant
Somnolence 3/1/2010 Female 9/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 45 Female 10/12/2010 Physician
Primary
Secondary
Concomitant
Mental Disorder Other Serious 45 Female 10/13/2010 Physician United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2009 52 Female 158 lb 10/27/2010 Consumer United States
Primary
Concomitant
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Other Serious 45 Female 10/29/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/3/2010 Physician United States
Primary
Secondary
Heart Rate Increased 7/1/2010 Female 11/19/2010 Physician
Primary
Concomitant
Mental Disorder Other Serious 45 Female 11/24/2010 Physician United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 11/8/2010 United States
Primary
Secondary
Mental Disorder Hospitalization 45 Female 12/1/2010 Other Health Professional United States
Primary
Secondary
Vision Blurred Other Serious 1/1/2009 52 Female 158 lb 7/15/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2009 52 Female 158 lb 12/16/2010 Consumer United States
Primary
Concomitant
Abdominal Distension Hospitalization 1/1/2009 52 Female 149 lb 12/31/2010 Consumer United States
Primary
Secondary
Concomitant
Abdominal Distension Hospitalization 1/1/2009 52 Female 149 lb 1/4/2011 Consumer United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2010 39 Female 135 lb 3/10/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 6/1/2010 62 Male 185 lb 4/11/2011 Physician United States
Primary
Secondary
Concomitant
Plantar Fasciitis Other Serious 6/27/2001 4/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/1/2010 48 Female 148 lb 4/29/2011 Consumer United States
Primary
Concomitant
Amnesia Other Serious 6/27/2001 5/4/2011 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 6/27/2001 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Nodule Other Serious 1/1/2009 52 Female 149 lb 5/17/2011 Consumer United States
Primary
Concomitant
Interacting
Feeling Abnormal Other Serious 1/1/2009 52 Female 149 lb 5/20/2011 Consumer United States
Primary
Secondary
Concomitant
Interacting
Drug Ineffective Female 5/26/2011 Pharmacist United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/14/2003 6/2/2011 United States
Primary
Secondary
Concomitant
Atrophic Vulvovaginitis Other Serious 10/14/2003 6/21/2011 Pharmacist United States
Primary
Secondary
Concomitant
Diverticulum Intestinal Hospitalization 10/14/2003 7/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 6/30/2011 42 Female 8/4/2011 Consumer United States
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Dyspnoea 3/1/2011 46 Female 8/31/2011 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal 1/1/2000 42 Male 194 lb 9/22/2011 Consumer United States
Primary
Concomitant
Muscle Spasms Hospitalization 3/1/2009 82 Female 152 lb 10/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Headache Female 132 lb 10/24/2011 Consumer United States
Primary
Concomitant
Drug Dose Omission Hospitalization Female 11/29/2011 Consumer United States
Primary
Concomitant
Hepatic Steatosis Hospitalization Female 110 lb 12/15/2011 Lawyer United States
Primary
Concomitant
Haemoglobin Decreased Death Female 136 lb 1/6/2012 Lawyer United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2011 40 Female 251 lb 12/27/2011 Pharmacist United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 1/12/2012 Lawyer United States
Primary
Concomitant
Swollen Tongue Female 1/23/2012 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2011 40 Female 251 lb 1/25/2012 Pharmacist United States
Primary
Concomitant
Lung Cancer Metastatic Death Male 2/21/2012 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/1/2012 42 Female 360 lb 2/7/2012 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Hospitalization 2/7/2012 62 Female 138 lb 2/27/2012 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2012 42 Female 360 lb 2/23/2012 Pharmacist United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 12/7/2011 38 Female 181 lb 3/20/2012 Other Health Professional United States
Primary
Concomitant
Device Related Infection Hospitalization 12/7/2011 38 Female 181 lb 4/10/2012 Other Health Professional United States
Primary
Concomitant
Candidiasis Other Serious 12/1/2011 40 Female 251 lb 3/22/2012 Pharmacist United States
Primary
Concomitant
Sinusitis Other Serious 12/1/2011 40 Female 251 lb 4/11/2012 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 8/1/2008 52 Female 130 lb 4/26/2012 Consumer United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication 7/1/2010 69 Male 5/2/2012 Other Health Professional United States
Primary
Concomitant
Device Related Infection Hospitalization 12/7/2011 38 Female 181 lb 5/8/2012 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 4/24/2012 54 Female 5/15/2012 Consumer United States
Primary
Concomitant
Cough Hospitalization 4/1/2012 56 Female 5/15/2012 Consumer United States
Primary
Concomitant

Drug Data