Spiriva combined with Theophylline

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pharmaceutical Product Complaint Hospitalization 1/8/2006 61 Male 1/11/2006 Consumer United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2005 56 Female 124 lb 1/12/2006 United States
Primary
Concomitant
Pharmaceutical Product Complaint Death Male 1/23/2006 Pharmacist Ireland
Primary
Concomitant
Sudden Cardiac Death Other Serious 73 Male 1/30/2006 Germany
Primary
Concomitant
Sensation Of Heaviness 40 Female 2/27/2006 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 9/15/2005 Male 3/16/2006 Physician Japan
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/8/2006 61 Male 3/20/2006 Consumer United States
Primary
Concomitant
Sudden Cardiac Death Other Serious 73 Male 3/21/2006 Germany
Primary
Concomitant
Death Death 2/1/2006 79 Male 3/28/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2005 Female 3/31/2006 Consumer United States
Primary
Concomitant
Vomiting 12/15/2005 63 Female 247 lb 1/20/2006 Consumer United States
Primary
Concomitant
Disease Progression Hospitalization 78 Male 4/10/2006 Physician United Kingdom
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 3/8/2006 Female 121 lb 4/13/2006 Physician Germany
Primary
Concomitant
Drug Ineffective 7/1/2005 72 Female 4/27/2006 Consumer United States
Primary
Concomitant
Dyspnoea 1/23/2006 68 Female 2/21/2006 United States
Primary
Concomitant
Dysgeusia 1/16/2006 62 Female 2/21/2006 United States
Primary
Concomitant
Ageusia 1/15/2006 77 Male 2/21/2006 United States
Primary
Concomitant
Dyspnoea 9/1/2005 71 Male 2/21/2006 Physician United States
Primary
Concomitant
Urticaria 10/1/2005 56 Male 2/21/2006 United States
Primary
Concomitant
Dyspnoea 10/26/2005 84 Female 2/21/2006 United States
Primary
Concomitant
Weight Decreased 10/19/2005 Female 2/21/2006 United States
Primary
Concomitant
Dysgeusia 10/1/2005 76 Male 2/21/2006 United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 3/8/2006 Female 121 lb 5/10/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/13/2006 83 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Tachypnoea Required Intervention 4/20/2006 63 Female 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Haemorrhage Other Serious 1/1/2005 Male 388 lb 6/4/2006 Consumer Germany
Primary
Concomitant
Disease Progression Hospitalization 78 Male 6/16/2006 Physician United Kingdom
Primary
Concomitant
Urinary Retention 10/1/2005 81 Male 138 lb 5/19/2006 Physician United States
Primary
Concomitant
Pneumonia 2/20/2006 60 Female 5/19/2006 United States
Primary
Concomitant
Unevaluable Event Other Serious 74 Female 6/26/2006 Consumer United States
Primary
Concomitant
Wheezing 3/18/2006 Male 5/19/2006 United States
Primary
Concomitant
Ageusia 12/27/2005 77 Male 5/19/2006 United States
Primary
Concomitant
Dysgeusia 1/16/2006 62 Female 5/19/2006 United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 3/8/2006 Female 121 lb 7/20/2006 Physician Germany
Primary
Concomitant
Epistaxis 10/1/2005 83 Female 8/4/2006 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 64 Female 7/28/2006 United States
Primary
Concomitant
Viral Infection Other Serious 7/5/2006 44 Female 8/10/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/3/2004 53 Female 260 lb 7/11/2006 Physician United States
Primary
Concomitant
Reflux Oesophagitis Other Serious 5/24/2006 73 Male 8/30/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 64 Female 8/31/2006 Other Health Professional United States
Primary
Concomitant
Dysgeusia Disability Male 205 lb 9/22/2006 Physician Belgium
Primary
Concomitant
Viral Infection Other Serious 7/5/2006 44 Female 139 lb 9/26/2006 Physician United States
Primary
Concomitant
Sudden Death Hospitalization 44 Female 160 lb 10/10/2006 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Haemorrhagic Other Serious 9/29/2006 73 Female 10/6/2006 United States
Primary
Concomitant
Pneumonia 2/20/2006 60 Female 8/22/2006 United States
Primary
Concomitant
Varicose Vein 4/25/2006 73 Male 192 lb 8/22/2006 Physician United States
Primary
Concomitant
Pollakiuria 6/1/2006 Male 8/22/2006 United States
Primary
Concomitant
Drug Ineffective 6/1/2006 61 Female 125 lb 8/22/2006 United States
Primary
Concomitant
Erectile Dysfunction 7/1/2004 Male 8/22/2006 United States
Primary
Concomitant
Oxygen Saturation Decreased 1/20/2006 65 Male 10/30/2006 Consumer United States
Primary
Concomitant
Dyspnoea 5/10/2006 59 Female 10/30/2006 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Viral 1/1/2006 54 Female 10/23/2006 Consumer United States
Primary
Concomitant
Joint Swelling Hospitalization 3/1/2006 71 Female 10/25/2006 Pharmacist United States
Primary
Concomitant
Sepsis Death 75 Male 110 lb 11/2/2006 Physician Germany
Primary
Concomitant
Metastatic Bronchial Carcinoma Death 1/1/2002 49 Male 172 lb 11/13/2006 Physician Germany
Primary
Concomitant
Breast Cancer Required Intervention 9/19/2005 66 Female 7/7/2006 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 78 Female 150 lb 12/8/2006 Physician Germany
Primary
Concomitant
Cardiopulmonary Failure Hospitalization 61 Male 234 lb 12/8/2006 Physician Germany
Primary
Concomitant
Pharmaceutical Product Complaint Death 7/28/2006 70 Male 12/13/2006 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 78 Female 150 lb 12/19/2006 Physician Germany
Primary
Concomitant
Vomiting Other Serious 12/5/2006 67 Male 164 lb 1/3/2007 Consumer United States
Primary
Concomitant
Cardiopulmonary Failure Other Serious 61 Male 234 lb 1/18/2007 Physician Germany
Primary
Concomitant
Rash Pruritic Hospitalization 11/1/2006 49 Female 183 lb 1/19/2007 Consumer United States
Primary
Secondary
Concomitant
Injection Site Extravasation Death 7/28/2006 70 Male 2/7/2007 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cells Semen 8/1/2006 82 Male 221 lb 11/21/2006 Physician United States
Primary
Concomitant
Drug Ineffective 12/1/2005 75 Female 11/21/2006 United States
Primary
Concomitant
Total Lung Capacity Decreased 10/1/2004 Male 11/21/2006 United States
Primary
Concomitant
Wheezing 3/18/2006 Male 11/21/2006 United States
Primary
Concomitant
Rash Pruritic Hospitalization 11/1/2006 49 Female 183 lb 2/19/2007 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 1/30/2007 64 Female 157 lb 2/16/2007 Physician Germany
Primary
Secondary
Concomitant
Tension 6/1/2006 74 Male 11/21/2006 Physician United States
Primary
Secondary
Concomitant
Musculoskeletal Pain 11/1/2005 Male 11/21/2006 United States
Primary
Concomitant
Lung Disorder Hospitalization 1/30/2007 64 Female 157 lb 3/6/2007 Physician Germany
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Death 7/28/2006 70 Male 3/12/2007 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 78 Male 3/19/2007 Physician United Kingdom
Primary
Concomitant
Rash Pruritic Hospitalization 11/1/2006 49 Female 183 lb 3/22/2007 Consumer United States
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 3/8/2006 Female 121 lb 4/27/2007 Physician Germany
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 3/1/2007 48 Female 88 lb 5/14/2007 Physician Hungary
Primary
Concomitant
Productive Cough Hospitalization 4/9/2007 81 Male 5/17/2007 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 3/8/2006 Female 121 lb 5/17/2007 Physician Germany
Primary
Concomitant
Throat Tightness 11/1/2006 Male 2/22/2007 United States
Primary
Concomitant
Productive Cough Hospitalization 4/9/2007 81 Male 5/25/2007 Consumer United States
Primary
Concomitant
Red Blood Cells Semen 8/1/2006 82 Male 221 lb 2/22/2007 United States
Primary
Concomitant
Ocular Hyperaemia 12/1/2006 70 Male 2/22/2007 United States
Primary
Concomitant
Dyspnoea 9/1/2006 73 Male 2/22/2007 United States
Primary
Secondary
Concomitant
Drug Ineffective 12/8/2006 84 Male 2/22/2007 United States
Primary
Concomitant
Vision Blurred 84 Female 2/22/2007 United States
Primary
Concomitant
Dissociation Other Serious 1/1/2006 Female 250 lb 6/1/2007 Consumer United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/1/2007 58 Female 6/1/2007 Consumer United States
Primary
Concomitant
Multi-organ Failure Death 1/23/2007 80 Male 81 lb 6/12/2007 Japan
Primary
Concomitant
Oedema Hospitalization Male 6/14/2007 Physician Singapore
Primary
Concomitant
Wound Dehiscence Other Serious 3/8/2006 Female 121 lb 6/15/2007 Physician Germany
Primary
Concomitant
Productive Cough Hospitalization 4/9/2007 81 Male 6/25/2007 Consumer United States
Primary
Concomitant
Skin Exfoliation Hospitalization 1/1/2007 58 Female 7/9/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2007 Female 200 lb 7/12/2007 United States
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 1/22/2007 80 Male 81 lb 7/17/2007 Japan
Primary
Concomitant
Wheezing Hospitalization 5/18/2007 Female 193 lb 7/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 7/1/2007 81 Female 146 lb 7/13/2007 Physician United States
Primary
Concomitant
Pulmonary Congestion Life Threatening Female 130 lb 8/10/2007 Consumer Germany
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/1/2007 51 Male 8/13/2007 Consumer United States
Primary
Concomitant
Intraductal Papilloma Of Breast Other Serious 1/18/2007 65 Female 8/15/2007 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 7/12/2007 70 Female 117 lb 8/9/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Obstruction Hospitalization 1/1/2005 67 Female 8/21/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 11/1/2006 63 Female 8/27/2007 Consumer United States
Primary
Concomitant
Dyspnoea Life Threatening Female 130 lb 8/28/2007 Consumer Germany
Primary
Concomitant
Drug Ineffective 2/1/2007 74 Female 9/6/2007 Consumer United States
Primary
Concomitant
Tongue Disorder Hospitalization 4/26/2007 78 Male 375 lb 9/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 7/12/2007 70 Female 117 lb 9/6/2007 Hungary
Primary
Secondary
Concomitant
Hypersomnia 4/1/2007 54 Male 135 lb 9/19/2007 United States
Primary
Concomitant
Weight Increased Other Serious 5/1/2007 Female 115 lb 9/20/2007 Other Health Professional United States
Primary
Concomitant
Prostate Examination Abnormal 8/1/2007 68 Male 9/21/2007 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Other Serious 7/25/2005 62 Female 195 lb 7/5/2007 Consumer United States
Primary
Concomitant
Productive Cough Hospitalization 3/25/2006 Female 10/2/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 262 lb 9/28/2007 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/1/2007 51 Male 10/8/2007 Consumer United States
Primary
Concomitant
Brain Neoplasm Death 76 Male 205 lb 10/9/2007
Primary
Concomitant
Viral Infection Hospitalization 7/12/2007 70 Female 117 lb 10/8/2007 Other Health Professional Hungary
Primary
Secondary
Concomitant
Brain Neoplasm Death 7/15/2007 Male 205 lb 10/18/2007
Primary
Concomitant
Brain Neoplasm Death 7/15/2007 Male 205 lb 10/18/2007
Primary
Concomitant
Brain Neoplasm Death 7/15/2007 Male 205 lb 10/18/2007
Primary
Concomitant
Ventricular Tachycardia Life Threatening 10/1/2007 75 Male 10/23/2007 Physician Germany
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 10/17/2006 73 Male 10/25/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 8/1/2005 77 Female 10/24/2007 Consumer United States
Primary
Concomitant
Stomach Discomfort 3/11/2007 73 Female 10/24/2007 Consumer United States
Primary
Concomitant
Epistaxis 9/5/2006 79 Female 10/25/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Disability 2/1/2007 92 Male 10/25/2007 Consumer United States
Primary
Concomitant
Urticaria 5/19/2007 69 Female 10/26/2007 Consumer United States
Primary
Concomitant
Dizziness Male 11/13/2007 Consumer United States
Primary
Concomitant
Pneumothorax Death 11/2/2007 63 Male 11/15/2007 Physician Korea, Republic Of
Primary
Secondary
Rhabdomyolysis Hospitalization 10/1/2007 84 Female 11/23/2007 Physician Germany
Primary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance 10/1/2005 64 Female 11/29/2007 Consumer United States
Primary
Concomitant
Eye Disorder 1/1/2006 Female 12/5/2007 Consumer United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Tendon Rupture Other Serious 3/16/2007 69 Female 10/17/2007 Physician United States
Primary
Concomitant
Disturbance In Attention Hospitalization 1/1/2007 Male 172 lb 12/12/2007 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/28/2006 83 Male 12/28/2007 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 12/23/2007 71 Male 160 lb 12/27/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 10/1/2007 84 Female 1/3/2008 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization Female 1/16/2008 Consumer United States
Primary
Concomitant
Visual Disturbance Female 1/17/2008 Consumer United States
Primary
Secondary
Concomitant
Oesophageal Candidiasis Other Serious 12/15/2005 70 Female 104 lb 1/31/2008 Physician Germany
Primary
Concomitant
Rash Male 2/5/2008 Physician United States
Primary
Concomitant
Heart Rate Increased 1/20/2008 Male 2/6/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 7/21/2005 63 Male 2/22/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 11/24/2007 75 Female 165 lb 2/29/2008 Physician Germany
Primary
Concomitant
Heart Rate Increased 1/20/2008 Male 3/4/2008 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 6/2/2007 56 Male 2/20/2008 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/1/2008 Male 220 lb 3/10/2008 Consumer United States
Primary
Concomitant

Drug Data