Sodium Bicarbonate combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 11/7/2006 61 Male 218 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Melaena Other Serious 4/10/2007 42 Male 7/10/2007 United Kingdom
Primary
Secondary
Concomitant
Melaena Other Serious 4/10/2007 42 Male 7/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 11/7/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased 84 Male 11/13/2007 Consumer United States
Primary
Concomitant
Proteinuria Death 1/1/2007 52 Female 235 lb 11/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Interacting
Proteinuria Death 1/9/2007 Female 235 lb 12/3/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 10/23/2007 8 Male 57 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Death 1/15/2008 79 Male 212 lb 2/6/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 76 Male 159 lb 2/21/2008 United States
Primary
Concomitant
Normochromic Normocytic Anaemia Other Serious 12/1/2007 Female 3/3/2008 Physician United States
Primary
Concomitant
Bronchiectasis Hospitalization 3/1/2006 36 Female 130 lb 3/12/2008 Other Health Professional United Kingdom
Primary
Concomitant
Aplasia Pure Red Cell Hospitalization 8/20/2007 Male 5/20/2008 Physician Sweden
Primary
Concomitant
Rectal Haemorrhage Hospitalization 3/6/2008 80 Female 5/28/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Function Test Abnormal Hospitalization 8/1/2007 Male 7/16/2008 Physician Sweden
Primary
Concomitant
Proteinuria Death 1/9/2007 Female 235 lb 8/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 52 Female 235 lb 8/5/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Function Test Abnormal Hospitalization 8/1/2007 Male 8/11/2008 Physician Sweden
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 8/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 76 Male 159 lb 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 74 Male 145 lb 8/26/2008 Physician United States
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 9/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Life Threatening 1/3/2006 58 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Restlessness Hospitalization 11/30/2008 67 Male 12/18/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Renal Function Test Abnormal Hospitalization 8/1/2007 Male 2/16/2009 Physician Sweden
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 3/31/2009 86 Female 4/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Renal Tubular Disorder Hospitalization 3/31/2009 86 Female 4/24/2009 United States
Primary
Secondary
Concomitant
Renal Failure Death 82 Male 6/10/2009 United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 1/29/2009 74 Male 6/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Hospitalization Male 6/14/2009 United States
Primary
Concomitant
Urinoma Hospitalization 11/13/2004 Male 163 lb 6/23/2009 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 7/1/2005 82 Male 6/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 82 Male 6/23/2009 United Kingdom
Primary
Concomitant
Renal Failure Death 82 Male 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 7/1/2005 82 Male 7/9/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 82 Male 7/10/2009 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 82 Male 7/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urine Output Decreased Death 82 Male 7/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Function Test Abnormal Hospitalization 8/1/2007 Male 7/16/2009 Physician Sweden
Primary
Concomitant
Renal Failure Chronic Other Serious 7/1/2005 82 Male 7/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Death 82 Male 7/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 12/29/2008 Female 8/6/2009 Physician Canada
Primary
Concomitant
Visual Impairment Hospitalization 78 Male 8/5/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Proteinuria Other Serious 1/1/2007 Female 235 lb 1/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Thrombocytopenia Other Serious 1/1/2008 71 Female 2/3/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Renal Tubular Disorder Hospitalization 3/31/2009 Female 3/30/2010 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/1/2008 34 Female 117 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 69 Female 4/19/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 4/26/2010 United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/1/2008 68 Female 4/26/2010 Lawyer United States
Primary
Concomitant
Tachycardia Other Serious 1/8/2008 68 Female 190 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/26/2010 81 Male 134 lb 5/20/2010 Pharmacist United States
Primary
Concomitant
Blood Calcium Increased 5/28/2009 68 Female 5/26/2010 United States
Primary
Concomitant
Peritonitis Bacterial Hospitalization 5/25/2010 72 Male 6/24/2010 Other Health Professional Philippines
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/10/2010 67 Male 155 lb 6/25/2010 United Kingdom
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/25/2008 65 Male 7/30/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 8/2/2010 United States
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 7/21/2010 68 Male 239 lb 7/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/15/2006 62 Female 123 lb 8/12/2010 United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 5/25/2010 72 Male 9/15/2010 Physician Philippines
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 71 Female 9/20/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Arrhythmia Other Serious 3/24/2008 81 Male 10/7/2010 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 66 Female 238 lb 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 10/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 9/20/2007 66 Female 190 lb 10/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Arrhythmia Other Serious 3/1/2008 81 Male 12/1/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Death 6/1/2007 12/6/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/17/2008 64 Female 328 lb 12/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Blood Creatinine Increased Hospitalization 7/20/2010 37 Male 208 lb 2/10/2011 Physician Belgium
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 11/18/2010 82 Female 158 lb 3/1/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastatic Malignant Melanoma Other Serious 11/18/2010 82 Female 158 lb 3/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cytomegalovirus Viraemia Hospitalization 12/30/2009 22 Male 141 lb 3/29/2011 Pharmacist United States
Primary
Concomitant
Nausea Other Serious 2/1/2008 65 Male 4/7/2011 Lawyer United States
Primary
Concomitant
Chronic Hepatitis Hospitalization 12/30/2009 22 Male 141 lb 4/7/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/6/2011 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Impulsive Behaviour Other Serious 1/1/2007 50 Female 150 lb 4/8/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Death 8/1/2010 87 Female 3/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Asthenia Other Serious 1/1/2005 61 Male 273 lb 5/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Discolouration Death 1/1/2005 61 Male 273 lb 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Death Hospitalization 10/1/2006 70 Male 295 lb 5/28/2011 Consumer United States
Primary
Concomitant
Resuscitation Hospitalization 3/6/2011 6/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lymphocele Other Serious 1/28/2011 62 Male 198 lb 6/9/2011 Physician France
Primary
Secondary
Concomitant
Impulsive Behaviour Other Serious 1/1/2007 50 Female 150 lb 6/27/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious 37 Female 6/22/2011 Lawyer United States
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 209 lb 6/30/2011 Consumer United Kingdom
Primary
Concomitant
Hypertension Other Serious Male 185 lb 6/30/2011 Consumer United States
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 209 lb 7/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 9/2/2009 73 Female 192 lb 7/20/2011 Consumer United Kingdom
Primary
Concomitant
Paraesthesia Death 1/1/2005 61 Male 273 lb 7/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/1/2004 63 Female 7/27/2011 Physician United States
Primary
Concomitant
Hyperkalaemia Death 5/27/2009 74 Female 106 lb 7/28/2011 Physician Japan
Primary
Concomitant
Dysstasia Death 10/1/2002 76 Female 188 lb 8/1/2011 Consumer United States
Primary
Concomitant
Death Death 5/6/2011 38 Female 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Aortic Valve Replacement Other Serious 1/1/2010 60 Male 157 lb 8/17/2011 Other Health Professional United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 176 lb 8/26/2011 Physician United Kingdom
Primary
Concomitant
Anaemia Death 11/12/2009 62 Female 101 lb 9/13/2011 Physician Japan
Primary
Concomitant
Wegener's Granulomatosis Hospitalization 22 Female 176 lb 9/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious Male 185 lb 9/14/2011 Physician United States
Primary
Concomitant
Cerebrovascular Disorder Other Serious 3/29/2004 47 Male 123 lb 9/16/2011 Physician United States
Primary
Concomitant
Gastroenteritis Viral Other Serious Female 9/16/2011 United States
Primary
Concomitant
Dementia Other Serious 8/29/1998 42 Male 123 lb 10/3/2011 Physician United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/12/2009 62 Female 101 lb 10/10/2011 Physician Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Death 5/6/2011 38 Female 10/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Lymphocyte Count Decreased Other Serious 6/1/2009 22 Female 176 lb 10/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Arteriovenous Shunt Operation Other Serious 1/1/2009 74 Male 170 lb 10/12/2011 Consumer United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Other Serious Female 10/14/2011 Physician United States
Primary
Concomitant
Condition Aggravated Hospitalization Female 176 lb 10/14/2011 Physician United Kingdom
Primary
Concomitant
Skin Induration Death 1/1/2005 61 Male 273 lb 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 11/12/2009 62 Female 101 lb 11/8/2011 Physician Japan
Primary
Concomitant
Hyperthermia Hospitalization 1/28/2011 62 Male 176 lb 11/14/2011 France
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 9/1/2011 77 Male 170 lb 11/16/2011 Consumer United States
Primary
Secondary
Concomitant
Mechanical Ventilation Hospitalization 8/10/2008 35 Female 127 lb 1/5/2012 Other Health Professional United States
Primary
Concomitant
Arterial Thrombosis Limb Hospitalization 12/23/2011 66 Female 146 lb 1/11/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/8/2012 76 Female 1/20/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/28/2010 82 Female 137 lb 2/1/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Disability 8/19/2011 50 Female 112 lb 2/9/2012 Physician Japan
Primary
Concomitant
Renal Disorder Other Serious 8/19/2011 50 Female 112 lb 3/1/2012 Physician Japan
Primary
Concomitant
Joint Range Of Motion Decreased Other Serious 2/1/2004 47 Female 128 lb 3/2/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Gastroenteritis Viral Other Serious 2/21/2012 53 Female 3/2/2012 Physician United States
Primary
Concomitant
Renal Disorder 8/19/2011 50 Female 112 lb 3/19/2012 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 1/3/2012 76 Male 3/13/2012 Japan
Primary
Concomitant
Pancreatic Insufficiency Other Serious 8/1/2009 66 Female 123 lb 4/6/2012 Lawyer United States
Primary
Concomitant
Agranulocytosis Other Serious 3/22/2012 30 Male 4/11/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Lymphocele Other Serious 1/28/2011 62 Male 176 lb 4/11/2012 France
Primary
Secondary
Concomitant

Drug Data