Sodium Bicarbonate combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Death 1/12/2007 72 Male 1/25/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/5/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 2/19/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/12/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/5/2007 Physician Japan
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 3/14/2007 Physician Japan
Primary
Concomitant
Superinfection Life Threatening 1/23/2007 80 Female 3/15/2007 Physician Japan
Primary
Concomitant
Urinary Retention Hospitalization 1/12/2007 71 Female 3/16/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 5/18/2007 Physician Japan
Primary
Concomitant
Pulmonary Mass Other Serious 12/4/2006 71 Male 5/24/2007 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 4/2/2007 63 Male 6/11/2007 Physician Japan
Primary
Concomitant
Troponin I Increased Other Serious 2/25/2007 61 Female 148 lb 6/8/2007 Pharmacist United Kingdom
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 6/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 6/28/2007 Physician Japan
Primary
Concomitant
Weight Increased Life Threatening 1/23/2007 80 Female 90 lb 7/6/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 8/16/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 9/17/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 9/18/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 10/10/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/23/2007 63 Male 10/22/2007 Physician Japan
Primary
Concomitant
Urinary Bladder Haemorrhage Life Threatening 1/23/2007 80 Female 90 lb 11/5/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/2006 71 Male 106 lb 11/22/2007 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/9/2007 58 Male 11/26/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 12/8/2006 71 Male 106 lb 12/14/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/8/2006 71 Male 106 lb 1/31/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/4/2007 64 Male 139 lb 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 2/22/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 3/10/2007 74 Male 101 lb 3/4/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/21/2007 46 Female 121 lb 3/20/2008 Physician Japan
Primary
Concomitant
Rash Other Serious 4/2/2007 71 Male 141 lb 3/19/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 9/10/2007 58 Male 126 lb 3/28/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/25/2007 55 Female 90 lb 3/31/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 2/20/2007 63 Male 3/31/2008 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 3/10/2007 74 Male 101 lb 4/10/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 1/19/2008 61 Male 123 lb 5/16/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 1/19/2008 61 Male 123 lb 6/12/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/4/2007 71 Female 126 lb 6/23/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/21/2008 71 Male 101 lb 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 6/26/2008 Physician Japan
Primary
Concomitant
Urinary Retention Other Serious 1/4/2007 71 Female 126 lb 7/9/2008 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Death 1/19/2008 61 Male 123 lb 7/15/2008 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 1/19/2008 61 Male 123 lb 7/24/2008 Physician Japan
Primary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 8/7/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/23/2008 71 Male 132 lb 8/14/2008 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 2/15/2008 60 Male 9/16/2008 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 2/15/2008 60 Male 9/29/2008 Physician United States
Primary
Secondary
Concomitant
Vulval Abscess Death 6/23/2008 60 Female 95 lb 10/2/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/12/2008 71 Male 132 lb 10/7/2008 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Death 6/5/2008 60 Female 95 lb 10/31/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 Male 12/12/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/12/2008 71 Male 132 lb 12/22/2008 Physician Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Life Threatening 3/20/2008 80 Female 86 lb 12/24/2008 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 12/13/2008 75 Male 134 lb 12/29/2008 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 9/19/2007 66 Female 101 lb 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/12/2008 71 Male 132 lb 1/2/2009 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Stenosis Life Threatening 3/20/2008 80 Female 86 lb 2/5/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/9/2007 58 Male 3/19/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/25/2007 55 Female 90 lb 3/23/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2005 Male 4/13/2009 Physician United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Life Threatening 10/9/2007 58 Male 4/23/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 7/9/2009 United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 5/19/2009 Male 8/4/2009 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2009 Male 8/24/2009 Physician United States
Primary
Concomitant
Polyneuropathy Other Serious 9/24/2007 77 Female 88 lb 9/2/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 9/24/2007 77 Female 88 lb 9/12/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 9/12/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Death 11/23/2007 62 Male 10/9/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/13/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/10/2007 74 Male 101 lb 10/15/2009 Physician Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 9/19/2007 66 Female 101 lb 10/16/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/4/2007 64 Male 139 lb 10/24/2009 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 4/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 4/26/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/27/2008 70 Male 139 lb 6/24/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 7/2/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/13/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 7/26/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 7/30/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 8/2/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/6/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/11/2010 United States
Primary
Secondary
Concomitant
Scrotal Swelling Other Serious 4/1/2009 59 Male 10/11/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/13/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 10/25/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 11/8/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 69 Male 142 lb 11/11/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/12/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/16/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/3/2010 United States
Primary
Secondary
Concomitant
Uveitis Hospitalization 6/22/2010 12/21/2010 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/18/2010 55 Female 164 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 63 Male 177 lb 12/30/2010 United States
Primary
Secondary
Concomitant
Hypercalcaemia Other Serious 6/28/2006 80 Male 1/6/2011 Lawyer United States
Primary
Secondary
Concomitant
Ligament Sprain Hospitalization 1/1/2005 63 Male 177 lb 1/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Myalgia Other Serious 1/1/2005 63 Male 177 lb 2/7/2011 United States
Primary
Secondary
Concomitant
Osteoarthritis Other Serious 1/1/2005 63 Male 177 lb 2/28/2011 United States
Primary
Secondary
Concomitant
Aortic Aneurysm Other Serious 1/1/2004 69 Male 142 lb 3/7/2011 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2005 63 Male 177 lb 3/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Death 6/4/2007 64 Male 139 lb 3/30/2011 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2004 69 Male 142 lb 4/28/2011 Physician United States
Primary
Secondary
Concomitant
Asteatosis Hospitalization 1/1/2005 63 Male 177 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperglycaemia Death 1/1/2005 63 Male 216 lb 5/23/2011 United States
Primary
Secondary
Concomitant
Osteosclerosis Hospitalization 1/1/2005 63 Male 216 lb 6/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Death 6/13/2011 71 Male 211 lb 6/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cough Death 1/1/2005 63 Male 216 lb 7/25/2011 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/1/2011 58 Female 8/10/2011 Physician United States
Primary
Concomitant
Acute Left Ventricular Failure Hospitalization 3/4/2011 80 Female 8/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Death 6/13/2011 71 Male 211 lb 8/19/2011 Consumer United States
Primary
Secondary
Concomitant
Facial Bones Fracture Other Serious 1/1/2005 63 Male 216 lb 8/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/13/2011 71 Male 211 lb 8/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/22/2010 10/26/2011 Physician Japan
Primary
Concomitant
Dyspepsia Hospitalization 1/1/2005 63 Male 216 lb 11/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Acute Left Ventricular Failure Life Threatening 3/4/2011 80 Female 11/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiomegaly Hospitalization 4/1/2011 12/6/2011 Other Health Professional France
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 6/22/2010 12/8/2011 Physician Japan
Primary
Concomitant
Pancytopenia Death 2/1/2011 74 Female 12/13/2011 Physician United States
Primary
Concomitant
Renal Failure Death 2/1/2011 74 Female 1/26/2012 Physician United States
Primary
Concomitant
Systolic Dysfunction Hospitalization 4/1/2011 4/20/2012 Physician France
Primary
Secondary
Concomitant
Mouth Haemorrhage Other Serious 6/28/2006 80 Male 6/20/2012 Physician United States
Primary
Secondary
Concomitant
Aphasia Hospitalization 7/13/2012 7/27/2012 Physician Germany
Primary
Concomitant
Pleural Effusion Other Serious 3/29/2012 70 Female 194 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Cavitation Hospitalization 7/5/2012 51 Male 144 lb 8/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Fall Hospitalization 7/2/2012 8/13/2012 Physician France
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 7/27/2012 8/15/2012 Physician France
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 7/5/2012 51 Male 144 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 3/29/2012 70 Female 194 lb 8/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Death 2004 Male 142 lb 11/6/2012 Consumer Us
Primary
Secondary
Concomitant
Septic Shock Death 2/25/2007 61 Female 148 lb 6/21/2007 Pharmacist Gb
Primary
Concomitant
Speech Disorder Hospitalization 7/13/2012 NotSpecified 2/27/2013 Physician De
Primary
Concomitant
Urinary Tract Infection Other Serious 12/21/2011 70 Female 198 lb 10/11/2012 Physician Us
Primary
Secondary
Concomitant
Bk Virus Infection Other Serious 6/17/2009 47 Male 10/24/2012 Physician Us
Primary
Secondary
Concomitant
Vertigo Hospitalization 7/2/2012 9/21/2012 Physician Fr
Primary
Secondary
Concomitant
Plasma Cell Myeloma Hospitalization 7/27/2012 NotSpecified 4/2/2013 Physician Fr
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/21/2011 70 Female 194 lb 10/3/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Haemorrhoidal Haemorrhage Hospitalization 3/20/2011 74 Male 11/20/2012 Other Health Professional Us
Primary
Concomitant
Thrombocytopenia Other Serious 1/28/2013 77 Male 4/24/2013 Physician Us
Primary
Secondary
Concomitant
Inflammation Hospitalization 3/4/2013 NotSpecified 5/9/2013 Physician Fr
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/31/2013 NotSpecified 5/16/2013 Physician Au
Primary
Secondary
Concomitant
Hypernatraemia Other Serious NotSpecified 9/5/2013 Consumer Jp
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/31/2012 NotSpecified 8/29/2013 Physician Au
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/2013 71 Male 170 lb 10/4/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2004 72 Male 142 lb 12/30/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 2005 67 Male 216 lb 8/2/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data