Sildenafil combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wrong Drug Administered Hospitalization 1/5/2006 54 Female 1/26/2006 Pharmacist United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/1/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/9/2006 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 3/3/2006 56 Female 3/16/2006 Ireland
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/24/2006 76 Female 3/24/2006 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/3/2006 Pharmacist Ireland
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/12/2006 Pharmacist Ireland
Primary
Concomitant
Pharyngolaryngeal Pain 40 Female 136 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 64 Female 190 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Vasculitis Other Serious 8/28/2006 38 Male 225 lb 9/7/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 9/15/2005 49 Female 9/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 9/7/2006 Consumer United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 40 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Nausea 59 Female 155 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Nausea 5/4/2006 23 Female 98 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Somnolence 4/24/2006 60 Female 180 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Stomatitis 4/1/2006 49 Male 173 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/21/2006 13 Male 77 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/21/2006 11 Male 77 lb 10/5/2006 Physician United States
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 8/18/2006 50 Female 145 lb 10/6/2006 United States
Primary
Concomitant
Urinary Retention Life Threatening 9/29/2006 55 Male 10/17/2006 Ireland
Primary
Concomitant
Subdural Haematoma Death 57 Male 7/15/2009 Physician United States
Primary
Concomitant
Organ Transplant Other Serious 60 Female 130 lb 11/30/2009 Other Health Professional Belgium
Primary
Concomitant
Pulmonary Arterial Hypertension Other Serious 10/31/2003 60 Female 130 lb 12/11/2009 Other Health Professional Belgium
Primary
Concomitant
Sepsis Hospitalization 1/1/2009 Male 12/31/2009 Physician Germany
Primary
Concomitant
Off Label Use Hospitalization 8/29/2008 14 Male 87 lb 1/8/2010 United Kingdom
Primary
Concomitant
Death Death 1/9/2010 Male 268 lb 1/18/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 1/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Death Hospitalization 10/25/2009 Female 275 lb 1/27/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 63 Male 192 lb 4/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 10/1/2007 63 Male 193 lb 5/14/2010 Lawyer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 10 Male 59 lb 5/28/2010 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 2/2/2010 63 Male 216 lb 8/26/2010 Physician Netherlands
Primary
Concomitant
Nausea Death 3/27/2007 12/6/2010 Other Health Professional United States
Primary
Concomitant
Productive Cough Death 10/1/2006 12/6/2010 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 11/13/2010 2 Female 20 lb 12/9/2010 Physician Poland
Primary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/26/2010 88 Female 129 lb 12/20/2010 Other Health Professional Australia
Primary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2007 63 Male 192 lb 1/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/17/2011 67 Male 139 lb 2/7/2011 Pharmacist United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 11/1/2010 2/26/2011 Physician Germany
Primary
Concomitant
Hemiplegia Life Threatening 10/26/2010 12 Female 99 lb 3/2/2011 Physician Austria
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 2/14/2011 59 Female 203 lb 3/15/2011 Physician Spain
Primary
Concomitant
Pyrexia Hospitalization 10/26/2010 12 Female 99 lb 3/16/2011 Physician Austria
Primary
Secondary
Concomitant
Palpitations Hospitalization 2/10/2011 33 Female 218 lb 3/17/2011 Physician Germany
Primary
Concomitant
Hyponatraemia Hospitalization 2/14/2011 59 Female 203 lb 3/22/2011 Physician Spain
Primary
Concomitant
Abdominal Distension Hospitalization 9/28/2007 3/23/2011 Physician United States
Primary
Concomitant
Cardiac Failure Hospitalization 11/1/2010 3/26/2011 Physician Germany
Primary
Concomitant
Urine Odour Abnormal Hospitalization 9/28/2007 4/11/2011 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious Female 291 lb 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Deafness Disability 9/1/2011 10/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 7/1/2011 10/28/2011 Pharmacist United States
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 10/21/2011 8 Female 11/1/2011 Physician Colombia
Primary
Concomitant
Disease Progression Death Male 11/7/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 10/4/2011 51 Male 11/7/2011 Pharmacist United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 10/1/2010 42 Male 11/11/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 10/21/2011 8 Female 11/10/2011 Physician Colombia
Primary
Concomitant
Headache Hospitalization 10/3/2011 51 Male 11/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 10/27/2011 12/1/2011 Physician United States
Primary
Concomitant
Hypercapnia Death 10/12/2011 79 Male 205 lb 12/2/2011 Other Health Professional Australia
Primary
Concomitant
Erythema Hospitalization 10/3/2011 51 Male 12/8/2011 Physician United States
Primary
Secondary
Concomitant
Flushing Hospitalization 10/4/2011 51 Male 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/4/2011 12/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Device Malfunction Other Serious 6/21/2011 12/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Transfusion Reaction Other Serious 6/21/2011 1/9/2012 Physician United States
Primary
Secondary
Concomitant
Transfusion Hospitalization 3/4/2011 1/9/2012 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Death 12/16/2011 1/12/2012 Pharmacist United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 9/28/2007 1/18/2012 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 2/1/2004 1/19/2012 Other Health Professional United States
Primary
Concomitant
Gastroenteritis Viral Other Serious 12/1/2009 47 Female 152 lb 1/27/2012 Physician Germany
Primary
Secondary
Concomitant
Interacting
General Physical Health Deterioration Hospitalization 11/2/2010 57 Female 114 lb 1/27/2012 Physician United Kingdom
Primary
Concomitant
Palpitations Death 11/1/2010 2/21/2012 Physician Germany
Primary
Concomitant
Right Ventricular Failure Death 10/27/2011 2/22/2012 Other Health Professional United States
Primary
Concomitant
Death Death 2/1/2012 3/9/2012 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/14/2012 1 Female 3/26/2012 Pharmacist United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 3/19/2012 4/4/2012 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Other Serious 12/22/2008 4/6/2012 Physician Germany
Primary
Concomitant
Gastrointestinal Arteriovenous Malformation Hospitalization 3/19/2012 4/16/2012 Physician United States
Primary
Secondary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 3/15/2012 4/17/2012 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 3/19/2012 4/26/2012 Physician United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 4/8/2012 69 Female 5/8/2012 Other Health Professional United States
Primary
Concomitant
Klebsiella Bacteraemia Hospitalization 10/1/2011 5/9/2012 Other Health Professional United States
Primary
Concomitant
Escherichia Infection Hospitalization 3/19/2012 5/11/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Hospitalization 3/15/2012 5/15/2012 Physician United States
Primary
Concomitant
Syncope Hospitalization 3/19/2012 5/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Life Threatening 3/9/2012 3 Male 4/25/2012 Finland
Primary
Secondary
Concomitant
Sepsis Other Serious 6/1/2008 6/1/2012 Physician United States
Primary
Concomitant
Apnoea Death 2/6/2008 6/20/2012 Consumer Germany
Primary
Concomitant
Small Cell Lung Cancer Stage Unspecified Hospitalization 8/1/2011 70 Female 6/26/2012 Physician Sweden
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 4/1/2012 6/28/2012 Physician United States
Primary
Secondary
Concomitant
Death Death 4/8/2012 65 Female 7/3/2012 Pharmacist United States
Primary
Concomitant
Hepatomegaly Hospitalization 63 Male 7/9/2012 Physician Australia
Primary
Concomitant
Hyponatraemia Hospitalization 60 Female 7/16/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious 62 Female 7/16/2012 Physician United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 6/24/2012 7/17/2012 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 62 Female 7/17/2012 Physician United Kingdom
Primary
Concomitant
Cardiac Arrest Death 7/8/2012 78 Female 117 lb 7/18/2012 Other Health Professional Australia
Primary
Concomitant
Oedema Hospitalization 6/24/2012 7/19/2012 Pharmacist United States
Primary
Concomitant
Hyponatraemia Other Serious 60 Female 7/23/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Normal Newborn Other Serious 33 Female 170 lb 7/24/2012 Physician Brazil
Primary
Concomitant
Urinary Tract Infection Death 11/1/2010 7/26/2012 Physician Germany
Primary
Concomitant
Chest Discomfort Hospitalization 10/1/2011 45 Female 7/30/2012 Pharmacist United States
Primary
Concomitant
Cellulitis Hospitalization 59 Female 8/1/2012 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/21/2012 74 Female 151 lb 8/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Caesarean Section Other Serious 3/9/2009 37 Female 8/6/2012 Physician United States
Primary
Concomitant
Atelectasis Hospitalization 10/1/2011 45 Female 8/7/2012 Pharmacist United States
Primary
Concomitant
Eye Swelling Hospitalization 6/24/2012 52 Male 8/10/2012 Physician United States
Primary
Concomitant
Splenomegaly 69 Female 8/13/2012 Physician Spain
Primary
Secondary
Concomitant
Fatigue Hospitalization 8/1/2012 52 Male 165 lb 8/14/2012 Physician France
Primary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 7/20/2012 65 Female 110 lb 8/15/2012 Physician Germany
Primary
Concomitant
Pain In Jaw Other Serious 8/16/2012 10 Male 59 lb 8/23/2012 Consumer United States
Primary
Concomitant
Urine Odour Abnormal Hospitalization 2/2004 53 Female 11/24/2012 Pharmacist Us
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 11/9/2010 57 Female 114 lb 4/24/2013 Other Health Professional De
Primary
Concomitant
Staphylococcal Bacteraemia Hospitalization 10/2011 45 Female 9/6/2012 Physician Us
Primary
Concomitant
Death Death 1/17/2012 51 Male 11/19/2012 Physician Us
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 4/2012 65 Female 353 lb 11/8/2012 Pharmacist Us
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 6/24/2012 52 Male 11/20/2012 Pharmacist Us
Primary
Concomitant
Product Quality Issue Other Serious 8/1/2012 52 Male 165 lb 6/17/2013 Consumer Ch
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 8/2012 67 Female 9/7/2012 Pharmacist Us
Primary
Concomitant
Vomiting Other Serious 8/3/2012 37 Female 194 lb 11/13/2012 Other Health Professional Us
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 5/8/2012 48 Female 10/5/2012 Physician Ir
Primary
Secondary
Concomitant
Gastrointestinal Bacterial Infection Hospitalization 75 Female 10/19/2012 Pharmacist Us
Primary
Concomitant
Vomiting Hospitalization 8/2012 Male 153 lb 9/26/2012 Other Health Professional Au
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 8/31/2012 64 Male 10/17/2012 Pharmacist Us
Primary
Concomitant
Torsade De Pointes Life Threatening 9/30/2012 NotSpecified 4/9/2013 Other Health Professional Kr
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/19/2012 2 Female 21 lb 10/22/2012 Pharmacist Us
Primary
Concomitant
Fall Hospitalization 10/6/2012 69 Female 11/2/2012 Pharmacist Us
Primary
Concomitant
Pulmonary Arterial Hypertension Death 10/19/2012 70 Female 11/20/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sedation Life Threatening 81 Female 154 lb 11/8/2012 Physician Nl
Primary
Concomitant
Ventricular Dysfunction Death 9/4/2012 32 Male 12/21/2012 Pharmacist Us
Primary
Concomitant
Dyspnoea Life Threatening 12/19/2012 67 Female 165 lb 1/17/2013 Physician De
Primary
Concomitant
Surgery Hospitalization 6/18/2012 5 Male 2/5/2013 Other Health Professional Us
Primary
Concomitant
Pulmonary Arterial Hypertension 78 Female 3/12/2013 Physician Nl
Primary
Secondary
Right Ventricular Failure Death Male 2/7/2013 Consumer Us
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 3/6/2013 Physician Us
Primary
Concomitant
Walking Distance Test Abnormal Other Serious 1/23/2013 67 Female 5/15/2013 Physician Au
Primary
Concomitant
Vomiting Hospitalization Male 2/19/2013 Other Health Professional Us
Primary
Concomitant
Heart Disease Congenital Death 12/4/2012 3 Male 3/21/2013 Pharmacist Us
Primary
Concomitant
Pulmonary Arterial Hypertension Hospitalization 11/28/2012 17 Female 137 lb 4/10/2013 Physician Pl
Primary
Concomitant
Weight Decreased Other Serious 2013 35 Female 5/10/2013 Physician De
Primary
Concomitant
Surgery Hospitalization 1 Male 4/29/2013 Physician Us
Primary
Concomitant
Staphylococcal Infection Hospitalization 4/8/2013 61 Female 4/29/2013 Physician Us
Primary
Concomitant
Death Hospitalization 4/29/2013 66 Female 5/6/2013 Physician Us
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 25 Male 5/21/2013 Other Health Professional Us
Primary
Concomitant

Drug Data