Sildenafil Citrate combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Other Serious 1/1/2005 58 Male 2/13/2006 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2006 24 Female 108 lb 2/17/2006 Physician Romania
Primary
Concomitant
Tinnitus Other Serious 5/27/2004 50 Female 223 lb 2/21/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Septal Defect Other Serious 1/1/2006 24 Female 108 lb 2/22/2006 Physician Romania
Primary
Concomitant
Vomiting Other Serious 1/1/2006 24 Female 108 lb 2/24/2006 Physician Romania
Primary
Concomitant
Vein Disorder Other Serious 9/7/2005 20 Female 121 lb 2/27/2006 Physician United States
Primary
Concomitant
Syncope Other Serious 1/1/2005 58 Male 3/10/2006 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 1/1/2005 58 Male 193 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/19/2006 Physician France
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/27/2006 Physician France
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/26/2006 Physician France
Primary
Concomitant
Pneumonia Life Threatening 3/3/2006 56 Female 4/26/2006 Pharmacist Ireland
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 56 Female 5/12/2006 Physician United Kingdom
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 5/15/2006 Physician France
Primary
Concomitant
Platelet Count Decreased Other Serious 12/1/2005 1 Female 5/18/2006 Pharmacist Ireland
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 47 Female 123 lb 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Cardiac Operation Other Serious 11/1/2005 Female 5/23/2006 Physician Brazil
Primary
Concomitant
Melaena Hospitalization 4/27/2006 56 Female 5/26/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 6/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/21/2006 47 Female 155 lb 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 10/13/2005 49 Female 157 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 8/2/2006 29 Female 108 lb 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Subileus Hospitalization 4/27/2006 53 Female 90 lb 8/23/2006 Japan
Primary
Concomitant
Urticaria Hospitalization 8/2/2006 29 Female 108 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Lesion Hospitalization 8/2/2006 29 Female 108 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/1/2006 France
Primary
Concomitant
Right Ventricular Failure Other Serious 3/25/2006 53 Female 123 lb 9/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/19/2006 France
Primary
Concomitant
Vomiting Other Serious 54 Female 90 lb 9/25/2006 Physician France
Primary
Concomitant
Catheterisation Cardiac Other Serious Female 9/26/2006 Physician Brazil
Primary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oesophageal Ulcer Hospitalization 4/27/2006 56 Female 10/24/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Helicobacter Infection Hospitalization 4/27/2006 56 Female 11/16/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Subileus Hospitalization 4/27/2006 54 Female 90 lb 12/6/2006 Japan
Primary
Concomitant
Right Ventricular Failure Other Serious 6/30/2006 63 Male 121 lb 12/18/2006 Physician Japan
Primary
Secondary
Concomitant
Gingival Bleeding 7/18/2006 40 Female 235 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Dry Throat 1/1/2006 47 Female 130 lb 10/24/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 4/27/2006 54 Female 90 lb 2/21/2007 Japan
Primary
Concomitant
Angioedema 10/7/2006 Female 2/26/2007 Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/17/2007 68 Female 130 lb 3/30/2007 Consumer United States
Primary
Concomitant
Myalgia 11/8/2006 71 Female 116 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 1/1/2006 64 Female 240 lb 1/23/2007 Consumer United States
Primary
Concomitant
Oral Pain 10/1/2006 58 Female 200 lb 1/23/2007 Consumer United States
Primary
Concomitant
Pharyngolaryngeal Pain 10/2/2006 40 Female 235 lb 1/23/2007 Consumer United States
Primary
Concomitant
Syncope 1/1/2005 19 Male 104 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Pharyngolaryngeal Pain 7/1/2005 61 Female 198 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Skin Ulcer Hospitalization 8/2/2006 29 Female 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/13/2007 10 Male 73 lb 5/1/2007 Colombia
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 5/14/2007
Primary
Concomitant
Vomiting Other Serious 3/17/2007 68 Female 96 lb 5/23/2007 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/25/2006 42 Female 148 lb 5/24/2007 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 15 Male 92 lb 5/18/2007 United States
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 6/15/2007 United States
Primary
Concomitant
Weight Increased Life Threatening 47 Male 143 lb 7/31/2007 Physician United Kingdom
Primary
Concomitant
Central Line Infection Required Intervention 4/3/2007 36 Female 154 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 9/12/2007 33 Female 119 lb 12/19/2007 Consumer Japan
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 1/5/2008 Male 203 lb 1/18/2008 United States
Primary
Concomitant
Atrial Flutter Hospitalization 1/10/2008 Female 124 lb 1/24/2008 United States
Primary
Concomitant
Death Death 12/16/2007 Male 1/29/2008 Physician United States
Primary
Concomitant
Headache Hospitalization 1/12/2008 Female 280 lb 2/1/2008 United States
Primary
Concomitant
Atrial Flutter Hospitalization 1/10/2008 Female 124 lb 3/14/2008 United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 1/17/2007 Female 182 lb 4/10/2008 United States
Primary
Concomitant
Syncope Other Serious 1/1/2007 20 Male 154 lb 4/21/2008 Consumer Brazil
Primary
Concomitant
Infusion Related Reaction Death 4/23/2008 Female 145 lb 4/30/2008 Pharmacist United States
Primary
Concomitant
Lipodystrophy Acquired Hospitalization 1/8/2008 Male 172 lb 5/2/2008 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Life Threatening 1 Female 12 lb 5/9/2008 Other Health Professional Ireland
Primary
Concomitant
Rash Female 96 lb 5/30/2008 Consumer United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 2/12/2007 2 Male 5/23/2008 Other Health Professional Ireland
Primary
Concomitant
Supraventricular Tachycardia Other Serious 1/19/2006 39 Female 6/11/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/5/2005 Female 104 lb 7/2/2008 United States
Primary
Concomitant
Interacting
Respiratory Syncytial Virus Bronchiolitis Other Serious 10/19/2007 0 Male 4 lb 7/1/2008 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 4/27/2006 Female 7/18/2008 United Kingdom
Primary
Secondary
Concomitant
Lipohypertrophy Hospitalization 3/10/2008 Male 172 lb 7/21/2008 Physician Brazil
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Bronchiolitis Other Serious 10/19/2007 0 Male 4 lb 8/20/2008 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Hospitalization 8/17/2008 Male 185 lb 9/24/2008 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2008 Male 185 lb 9/26/2008 United States
Primary
Concomitant
Neutropenia Hospitalization 8/29/2008 14 Male 87 lb 9/25/2008 United Kingdom
Primary
Concomitant
Ventricular Failure Other Serious 9/21/2008 56 Male 225 lb 10/13/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Failure Other Serious 8/14/2008 56 Male 225 lb 10/28/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Required Intervention 9/22/2008 56 Female 10/13/2008 Pharmacist United States
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/10/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 3/15/2006 7 Male 40 lb 12/11/2008 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 11/20/2008 12/19/2008 Physician Poland
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 12/2/2008 12/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2008 12/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/29/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/27/2008 Female 1/7/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Acute Life Threatening 12/18/2008 1 Female 12/23/2008 Slovenia
Primary
Concomitant
Death Death 10/3/2008 1/8/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cardiac Failure Death 12/24/2008 1/16/2009 Physician India
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/1/2008 3 Female 1/16/2009 Physician United States
Primary
Concomitant
Pulmonary Arterial Hypertension Death 10/3/2008 1/30/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 6/15/2006 Female 204 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 1/1/2009 1 Male 11 lb 1/26/2009 Israel
Primary
Concomitant
Cardiac Failure Death 12/24/2008 2/23/2009 Physician India
Primary
Concomitant
Weight Decreased Other Serious 12/1/2008 2/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/15/2006 7 Male 40 lb 2/20/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization Female 3/9/2009 Other Health Professional Japan
Primary
Secondary
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 3/23/2009 Other Health Professional United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 3/30/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/9/2009 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Acute Life Threatening 12/18/2008 Female 4/8/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 4/13/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 3/1/2009 62 Female 154 lb 4/17/2009 Physician United Kingdom
Primary
Concomitant
Electrocardiogram Change Hospitalization 3/31/2008 Female 121 lb 4/20/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 4/7/2006 4/21/2009 Physician France
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 Female 154 lb 4/27/2009 Physician United Kingdom
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/26/2008 64 Male 256 lb 4/29/2009 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Hospitalization 6/1/2006 Female 4/30/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 10/5/2005 Female 104 lb 4/30/2009 United States
Primary
Concomitant
Interacting
Platelet Count Decreased Hospitalization 6/1/2006 Female 5/1/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization Female 5/6/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2009 Female 154 lb 5/13/2009 Physician United Kingdom
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/7/2009 36 Male 5/14/2009 Physician United States
Primary
Concomitant
Viral Infection Hospitalization 4/13/2005 50 5/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Catheter Related Infection Hospitalization 10/8/2006 54 5/26/2009 Other Health Professional Israel
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 5/29/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 4/7/2006 40 5/29/2009 Physician France
Primary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 6/4/2009 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/9/2009 35 6/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 3/1/2009 Male 168 lb 6/9/2009 Physician United States
Primary
Concomitant
Inguinal Hernia Hospitalization 11/10/2008 Male 163 lb 6/12/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 6/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 68 Male 179 lb 7/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 7/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 7/31/2009 Physician United Kingdom
Primary
Concomitant
Platelet Production Decreased Other Serious 73 Male 375 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 4/8/2009 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 66 Female 132 lb 9/2/2009 Physician United Kingdom
Primary
Concomitant
Benign Intracranial Hypertension Hospitalization 3/13/2009 36 9/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Veno-occlusive Disease Hospitalization 2/4/2008 67 Female 10/22/2009 Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 10/16/2008 Male 227 lb 12/14/2009 Other Health Professional United States
Primary
Concomitant
Iron Deficiency Other Serious 6/14/2009 69 Female 143 lb 1/6/2010 Physician Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 42 Male 1/8/2010 Other Health Professional Greece
Primary
Secondary
Ventricular Tachycardia Required Intervention 42 Male 1/21/2010 Greece
Primary
Secondary
Congenital Mitral Valve Stenosis Death 1/5/2009 2 Male 11 lb 2/24/2010 Other Health Professional Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/1/2009 49 Female 213 lb 2/17/2010 Physician Canada
Primary
Concomitant
Right Ventricular Failure Other Serious 6/27/2008 1 Male 4/12/2010 Japan
Primary
Concomitant
Ventricular Septal Defect Other Serious 5/26/2008 1 Male 9 lb 4/30/2010 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/8/2010 54 Male 6/7/2010 Germany
Primary
Concomitant
Pyrexia Hospitalization 5/23/2010 39 Female 101 lb 6/8/2010 Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 5/19/2009 78 Female 6/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 12/1/2008 16 Female 104 lb 6/24/2010 Poland
Primary
Concomitant

Drug Data