Sevoflurane combined with Vecuronium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Procedural Complication Life Threatening 42 Female 1/2/2006 Physician Japan
Primary
Secondary
Spinal Cord Infarction Other Serious 83 Male 1/19/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Spinal Cord Infarction Disability 83 Male 1/19/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 1/24/2006 Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia 6/17/2005 Female 1/24/2006 Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia 6/27/2005 Female 1/24/2006 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 8/16/2005 Male 1/31/2006 Japan
Primary
Concomitant
Injection Site Swelling Hospitalization 1/16/2006 55 Male 2/14/2006 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 75 Male 108 lb 2/17/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Required Intervention 12/13/2005 57 Male 148 lb 3/2/2006 Physician Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Required Intervention 15 Male 119 lb 3/22/2006 Physician Japan
Primary
Concomitant
Procedural Complication 3/15/2006 37 Female 3/31/2006 Japan
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 4/17/2006 Other Health Professional Japan
Primary
Concomitant
Procedural Complication Life Threatening 1/13/2006 17 Female 1/23/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure 3/15/2006 37 Female 4/12/2006 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Required Intervention 11/27/2005 64 Male 4/12/2006 Pharmacist Japan
Primary
Concomitant
Thirst Other Serious 59 Female 4/21/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Polyuria Other Serious 3/7/2006 59 Female 4/24/2006 Japan
Primary
Secondary
Concomitant
Polyuria Other Serious 59 Female 4/27/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thirst Other Serious 59 Female 4/28/2006 Consumer Japan
Primary
Secondary
Concomitant
Thirst Other Serious 59 Female 5/1/2006 Consumer Japan
Primary
Secondary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 4/19/2006 United States
Primary
Concomitant
Anaphylactic Shock 4/26/2006 44 Male 5/5/2006 Italy
Primary
Secondary
Hypoventilation Life Threatening 1/13/2006 17 Female 5/17/2006 Japan
Primary
Concomitant
Tachycardia Required Intervention 38 Male 5/22/2006 Physician Japan
Primary
Concomitant
Blood Pressure Decreased 60 Female 5/24/2006 Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 21 Male 203 lb 6/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 1/20/2006 55 Male 5/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 6/6/2006 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Life Threatening 3/28/2006 71 Female 6/19/2006 Other Health Professional Japan
Primary
Concomitant
Proteinuria Other Serious 5/30/2006 Male 6/28/2006 Other Health Professional Japan
Primary
Secondary
Vascular Injury Life Threatening 3/28/2006 71 Female 6/27/2006 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5 Male 42 lb 7/10/2006 United States
Primary
Secondary
Concomitant
Airway Complication Of Anaesthesia 60 Female 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 18 Female 7/24/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Life Threatening 7/18/2006 83 Male 123 lb 8/3/2006 Pharmacist Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 8/7/2006 Other Health Professional Japan
Primary
Concomitant
Tachycardia 4/26/2006 44 Female 7/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Rash Other Serious 7/18/2006 83 Male 123 lb 8/14/2006 Pharmacist Japan
Primary
Concomitant
Extrasystoles 2/24/2005 18 Female 8/16/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 7/18/2006 83 Male 123 lb 8/17/2006 Pharmacist Japan
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 9/18/2006 Other Health Professional Japan
Primary
Concomitant
Tracheal Stenosis Life Threatening 5/10/2006 61 Female 9/28/2006 Physician Japan
Primary
Concomitant
Rash Other Serious 7/18/2006 83 Male 123 lb 10/3/2006 Pharmacist Japan
Primary
Concomitant
Proteinuria Other Serious 5/30/2006 Male 10/4/2006 Other Health Professional Japan
Primary
Secondary
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 127 lb 10/23/2006 Other Health Professional Japan
Primary
Concomitant
Wheezing Life Threatening 5/10/2006 61 Female 10/27/2006 Physician Japan
Primary
Concomitant
Bronchospasm Life Threatening 1/13/2006 17 Female 10/18/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 10/30/2006 Japan
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 15 Female 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 55 Female 121 lb 10/31/2006 Other Health Professional Japan
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 70 Male 11/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 11/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Atrioventricular Block Third Degree Life Threatening 36 Male 11/3/2006 Japan
Primary
Concomitant
Procedural Complication Other Serious 7/21/2006 6 Male 11/8/2006 Other Health Professional Japan
Primary
Secondary
Hypoxia Life Threatening 75 Male 11/16/2006 Japan
Primary
Concomitant
Brugada Syndrome Other Serious 36 Male 11/17/2006 Japan
Primary
Secondary
Concomitant
Anaphylactoid Reaction 32 Female 11/7/2006 Other Health Professional Japan
Primary
Concomitant
Electrocardiogram St Segment Elevation Life Threatening 36 Male 11/9/2006 Other Health Professional Japan
Primary
Secondary
Pulmonary Oedema Other Serious 84 Female 11/17/2006 Japan
Primary
Secondary
Concomitant
Respiratory Tract Haemorrhage Life Threatening 75 Male 11/20/2006 Japan
Primary
Concomitant
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 5/10/2006 61 Female 123 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 29 Female 11/22/2006 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 55 Female 121 lb 11/27/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Disorder Other Serious 28 Female 11/8/2006 Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2005 67 Male 146 lb 11/28/2006 Japan
Primary
Concomitant
Procedural Complication 32 Female 11/15/2006 Japan
Primary
Concomitant
Tachycardia Hospitalization 8/3/2006 Female 11/30/2006 Other Health Professional Japan
Primary
Concomitant
Hypoxia Life Threatening 6/3/2006 Male 11/30/2006 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/1/2005 71 Male 137 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 12/6/2006 Japan
Primary
Concomitant
Urticaria Other Serious 5/2/2006 32 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Erythema Life Threatening 5/2/2006 32 Female 11/29/2006 Japan
Primary
Secondary
Concomitant
Blood Pressure Systolic Decreased Life Threatening 5/2/2006 32 Female 11/24/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 4/22/2006 Male 12/18/2006 Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 8/29/2005 81 Male 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/30/2004 14 Female 119 lb 12/20/2006 Other Health Professional Japan
Primary
Concomitant
Poor Peripheral Circulation Life Threatening 2 Male 12/15/2006 Turkey
Primary
Concomitant
Tachycardia Hospitalization 8/3/2006 Female 73 lb 1/3/2007 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Decreased Required Intervention 5/2/2006 32 Female 1/10/2007 Physician Japan
Primary
Secondary
Pulmonary Oedema Other Serious 28 Female 12/28/2006 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 61 Male 130 lb 1/19/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Female 1/19/2007 Japan
Primary
Concomitant
Pyrexia Hospitalization 61 Male 130 lb 1/30/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 1/1/2002 65 Female 2/1/2007
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 65 Female 2/1/2007 Japan
Primary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Myoglobin Blood Increased Hospitalization 61 Male 130 lb 1/30/2007 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 61 Female 150 lb 2/9/2007 Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 74 Male 128 lb 2/9/2007 Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 67 Female 93 lb 2/9/2007 Japan
Primary
Concomitant
Myoglobin Blood Increased Hospitalization 61 Male 130 lb 2/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/30/2004 14 Female 119 lb 2/19/2007 Japan
Primary
Concomitant
Medication Error Other Serious 5 Female 37 lb 2/26/2007 United States
Primary
Concomitant
Interacting
Pulmonary Embolism Other Serious 7/5/2006 Female 3/9/2007 Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 77 Male 3/16/2007 Japan
Primary
Concomitant
Tracheostomy 11 Male 3/12/2007 Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 77 Male 3/29/2007 Japan
Primary
Concomitant
Hot Flush Other Serious 12/28/2005 24 Male 132 lb 4/2/2007 Physician Japan
Primary
Concomitant
Paraplegia Disability 83 Male 86 lb 4/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/6/2007 Japan
Primary
Secondary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/11/2007 Japan
Primary
Secondary
Concomitant
Sinobronchitis Other Serious 31 Male 185 lb 4/19/2007
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious 4/11/2007 Male 159 lb 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Laryngeal Oedema Life Threatening 3/26/2007 51 Female 4/23/2007 Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/15/2007 Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/24/2007 Japan
Primary
Concomitant
Postoperative Fever Life Threatening 3 Male 20 lb 5/29/2007 Physician China
Primary
Secondary
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Death 2 Male 29 lb 6/19/2007 Japan
Primary
Secondary
Stress Cardiomyopathy Life Threatening 81 Male 6/26/2007 Other Health Professional Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 65 Male 6/27/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Death 2 Male 29 lb 6/27/2007 Japan
Primary
Secondary
Lung Disorder Other Serious 58 Male 6/28/2007 Other Health Professional Japan
Primary
Concomitant
Fat Embolism Other Serious 71 Female 128 lb 7/2/2007 Other Health Professional Japan
Primary
Concomitant
Drug Interaction Other Serious 80 Female 181 lb 7/2/2007 Japan
Primary
Concomitant
Interacting
Lung Disorder Other Serious 58 Male 7/6/2007 Other Health Professional Japan
Primary
Concomitant
Stress Cardiomyopathy Life Threatening 81 Male 7/6/2007 Other Health Professional Japan
Primary
Concomitant
Stress Cardiomyopathy Life Threatening 78 Male 112 lb 7/9/2007 Other Health Professional Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 65 Male 7/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/9/2007 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 5/8/2007 Male 7/26/2007 Other Health Professional Japan
Primary
Concomitant
Torsade De Pointes Other Serious 9/24/2006 62 Female 7/27/2007 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 9/28/2006 50 Female 7/27/2007 Japan
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 49 Male 7/30/2007 Physician Japan
Primary
Concomitant
Respiratory Depression Other Serious 49 Male 7/30/2007 Physician Japan
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/26/2007 Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 10/24/2000 12 Male 82 lb 8/2/2007 Japan
Primary
Secondary
Visual Acuity Reduced Other Serious 10/24/2000 12 Male 82 lb 8/2/2007 Japan
Primary
Secondary
Unwanted Awareness During Anaesthesia Other Serious 71 Male 126 lb 8/3/2007 Japan
Primary
Concomitant
Procedural Complication Life Threatening 5/12/2005 80 Female 8/2/2007 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 5/8/2007 Male 8/8/2007 Other Health Professional Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 76 Male 8/17/2007 Other Health Professional Japan
Primary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 71 Male 123 lb 8/24/2007 Japan
Primary
Concomitant
Visual Acuity Reduced Other Serious 10/18/2006 12 Male 82 lb 8/30/2007 Japan
Primary
Secondary
Pulmonary Embolism Life Threatening 65 Male 9/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 55 Male 130 lb 9/21/2007 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 69 Male 9/28/2007 Japan
Primary
Concomitant

Drug Data