Senna combined with Zopiclone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pharyngolaryngeal Pain Hospitalization 7/6/1999 53 Male 1/20/2006 Physician United Kingdom
Primary
Concomitant
Wheezing Hospitalization 7/6/1999 53 Male 1/24/2006 Physician United Kingdom
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 7/6/1999 53 Male 1/25/2006 Physician United Kingdom
Primary
Concomitant
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 3/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 3/6/2005 92 Female 3/27/2006 Physician United Kingdom
Primary
Concomitant
Interacting
Renal Failure Acute Other Serious 6/16/2003 68 Male 3/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 3/12/2006 58 Male 3/31/2006 Physician Canada
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Gerstmann's Syndrome Other Serious 3/9/2006 73 Female 4/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Other Serious 6/16/2003 68 Male 4/23/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 3/16/2003 68 Male 4/20/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Death 3/16/2003 68 Male 4/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypomagnesaemia Life Threatening 6/9/2006 62 Female 7/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Grand Mal Convulsion Disability 2/1/2005 52 Female 8/29/2006
Primary
Concomitant
Blood Potassium Decreased Life Threatening 6/9/2006 Female 9/1/2006 Consumer United Kingdom
Primary
Concomitant
Hypoglycaemia Other Serious 1/16/2006 23 Female 196 lb 9/12/2006 Consumer United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/11/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 3/15/2007 39 Female 132 lb 4/19/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 4/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 3/15/2007 70 Female 5/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sedation Other Serious Female 6/24/2007 Physician New Zealand
Primary
Concomitant
Visual Disturbance Other Serious 6/27/2007 69 Male 8/1/2007 Pharmacist United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2007 70 Female 251 lb 8/3/2007 Physician
Primary
Secondary
Concomitant
Tremor Other Serious 70 Female 8/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 3/10/2007 70 Female 8/20/2007 Physician
Primary
Secondary
Concomitant
Tremor Other Serious 5/18/2007 70 Female 8/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/18/2007 70 Female 8/30/2007 United Kingdom
Primary
Concomitant
Dental Caries Other Serious 12/2/2007 Female 1/18/2008 Pharmacist Canada
Primary
Concomitant
Neutropenia Other Serious 2/18/2008 86 Female 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 11/2/2007 71 Female 3/28/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Overdose Life Threatening 4/7/2008 Female 154 lb 6/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pruritus Life Threatening 4/7/2008 Female 154 lb 7/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Pruritus Life Threatening 4/7/2008 Female 154 lb 7/7/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2008 Female 93 lb 9/5/2008 United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 11/1/2008 Pharmacist Canada
Primary
Concomitant
Tremor Other Serious 10/8/2008 60 Female 125 lb 12/2/2008 Pharmacist Canada
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 4/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 4/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 49 Female 4/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 4/7/2009
Primary
Secondary
Concomitant
Sudden Death Death 49 Female 4/29/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 8/4/2008 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/4/2008 56 6/29/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 8/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Level Increased Death 8/27/2008 49 Female 8/18/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 8/25/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Death 49 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 49 Female 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Death 8/27/2008 49 Female 8/26/2009
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 9/9/2009 United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 10/21/2008 Female 196 lb 11/16/2009 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 8/27/2008 49 Female 12/1/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 63 Male 104 lb 12/1/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 49 Female 11/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Thirst Other Serious 3/13/2009 83 Male 205 lb 12/14/2009 Other Health Professional Canada
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/13/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tremor Other Serious 5/18/2007 70 Female 1/20/2010 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Sudden Death Death 8/27/2008 49 Female 1/27/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Level Above Therapeutic Death 8/27/2008 49 Female 2/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 2/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 4/21/2009 Female 183 lb 2/11/2010 Other Health Professional United Kingdom
Primary
Concomitant
Swelling Face Other Serious 1/16/2010 75 Female 102 lb 2/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 49 Female 2/17/2010 United Kingdom
Primary
Secondary
Concomitant
Swelling Face Hospitalization 1/16/2010 75 Female 102 lb 3/2/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Level Increased Death Female 3/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/26/2010 76 Male 5/19/2010 Physician United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/18/2010 79 Female 5/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 6/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 6/3/2010 Other Health Professional Italy
Primary
Concomitant
Neutropenic Sepsis Hospitalization 11/27/2007 71 Female 7/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 8/2/2010 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 6/25/2010 67 Male 8/20/2010 Physician United Kingdom
Primary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 8/30/2010 Consumer United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 7/25/2010 73 Male 119 lb 9/16/2010 Consumer United States
Primary
Secondary
Concomitant
Lung Consolidation Hospitalization 7/25/2010 74 Male 120 lb 9/10/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 9/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 7/25/2010 73 Male 119 lb 9/28/2010 Consumer United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 6/25/2010 67 Male 10/8/2010 Physician United Kingdom
Primary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 10/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/25/2010 74 Male 120 lb 10/27/2010 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/21/2010 75 Female 11/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Parathyroid Disorder Other Serious 7/1/2010 79 Female 96 lb 11/24/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Disability 12/25/2010 84 Male 198 lb 1/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Cerebral Disorder Other Serious 73 Female 2/2/2011 Pharmacist United Kingdom
Primary
Concomitant
General Physical Health Deterioration Hospitalization 7/25/2010 74 Male 120 lb 2/28/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
No Adverse Event 73 Female 3/24/2011 Pharmacist United Kingdom
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 3/15/2011 Other Health Professional Denmark
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 3/24/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 3/28/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Local Swelling Other Serious 3/3/2011 64 Male 3/30/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 4/3/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 2/18/2011 76 Female 3/31/2011 Other Health Professional Denmark
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 2/18/2011 76 Female 254 lb 4/28/2011 Other Health Professional United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/1/2010 65 Female 139 lb 5/9/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 1/31/2011 65 Male 7/19/2011 Physician Ireland
Primary
Concomitant
Dyspnoea Other Serious 5/1/2011 86 Female 7/20/2011 Consumer United Kingdom
Primary
Concomitant
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Cholelithiasis Other Serious 7/14/2011 49 Female 8/24/2011 Physician United Kingdom
Primary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 137 lb 9/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Disability 11/9/2009 82 Female 137 lb 9/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Disability 11/9/2009 82 Female 136 lb 9/13/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Teeth Brittle Other Serious 9/1/2009 65 Female 176 lb 9/20/2011 Consumer United Kingdom
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 4/21/2011 71 Female 9/23/2011 Other Health Professional United Kingdom
Primary
Concomitant
Teeth Brittle Other Serious 9/1/2009 65 Female 176 lb 10/11/2011 Physician United Kingdom
Primary
Concomitant
Parkinson's Disease Hospitalization 1/1/2011 88 Female 11/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/9/2011 69 Female 11/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Headache Other Serious 11/6/2011 41 Female 12/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Death Male 1/3/2012 Physician Ireland
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/9/2011 69 Female 1/5/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Off Label Use Death 5/31/2011 59 Male 1/9/2012 Physician United Kingdom
Primary
Concomitant
Fall Hospitalization 1/9/2012 63 Female 2/8/2012 Pharmacist United Kingdom
Primary
Concomitant
Prostate Cancer Metastatic Death 7/15/2011 72 Male 160 lb 2/15/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Dysarthria Other Serious 10/1/2009 57 Male 2/17/2012 Physician United Kingdom
Primary
Concomitant
Tension Headache Other Serious 10/1/2009 57 Male 2/27/2012 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 9/17/2011 58 Male 3/9/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Impairment Other Serious 8/19/2011 63 Female 3/12/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mental Impairment Disability 63 Female 3/14/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 9/17/2011 58 Male 3/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Schizophrenia Hospitalization 8/19/2011 63 Female 4/27/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Other Serious 5/15/2012 49 Female 127 lb 7/6/2012 Physician Hong Kong
Primary
Concomitant
Femoral Neck Fracture Hospitalization 12/8/2011 75 Female 152 lb 8/15/2012 Consumer United Kingdom
Primary
Concomitant
Femoral Neck Fracture Other Serious 12/8/2011 75 Female 152 lb 8/16/2012 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Prostate Death 4/10/2012 90 Male 174 lb 8/20/2012 Other Health Professional United Kingdom
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Disability 86 Male 154 lb 8/23/2012 Physician United Kingdom
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Disability 85 Male 154 lb 8/28/2012 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Metastatic Hospitalization 7/15/2011 73 Male 160 lb 2/15/2013 Physician Gb
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Other Serious 86 Male 154 lb 2/20/2013 Physician Gb
Primary
Concomitant
Sepsis Death 4/6/2012 44 Female 162 lb 10/30/2012 Physician Ca
Primary
Concomitant
Myositis Death 10/22/2012 75 Male 141 lb 12/3/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Myositis Death 10/22/2012 75 Male 141 lb 12/4/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Myositis Death 10/22/2012 75 Male 141 lb 12/5/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Myositis Death 10/22/2012 75 Male 141 lb 12/11/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Myositis Death 10/22/2012 75 Male 12/13/2012 Pharmacist Gb
Primary
Concomitant
Interacting
Myositis Other Serious 10/22/2012 75 Male 141 lb 12/14/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Haematemesis Other Serious 11/23/2012 21 Male 12/23/2012 Pharmacist Gb
Primary
Concomitant
Myositis Other Serious 10/22/2012 75 Male 141 lb 12/13/2012 Gb
Primary
Secondary
Concomitant
Drug-induced Liver Injury Other Serious 90 Male 187 lb 12/28/2012 Other Health Professional Ie
Primary
Concomitant
Neutropenic Sepsis Hospitalization 1/1/2013 65 Female 146 lb 1/30/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Cardiac Failure Death 1/4/2013 58 Male 119 lb 2/19/2013 Consumer Gb
Primary
Secondary
Concomitant
Malaise Other Serious 1/14/2013 67 Female 2/15/2013 Other Health Professional Gb
Primary
Concomitant

Drug Data