Senna combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Necrosis Life Threatening 8/26/2005 48 Female 222 lb 1/30/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 11/22/2005 73 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 11/22/2005 73 Female 2/8/2006 United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 2/24/2006 United States
Primary
Secondary
Concomitant
Syncope Life Threatening 10/26/2005 83 Female 1/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 68 Male 218 lb 4/19/2006 Pharmacist United States
Primary
Concomitant
Swollen Tongue Hospitalization 2/19/2006 84 Female 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 5/8/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 3/7/2006 Male 5/17/2006 Pharmacist United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 2/28/2005 62 Female 179 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vaginal Exfoliation Hospitalization 5/23/2006 Female 139 lb 7/13/2006 Physician United Kingdom
Primary
Concomitant
Myalgia Other Serious 5/19/2006 84 Female 7/13/2006 Pharmacist United States
Primary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Tremor Hospitalization 8/28/2006 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Wound Infection Other Serious 3/1/2006 60 Female 105 lb 10/30/2006 Physician United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 1/1/2002 86 Male 11/14/2006 United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 2/1/2003 Male 11/22/2006 United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 11/10/2006 86 Female 11/17/2006 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Haemorrhoidal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Required Intervention 7/11/2006 74 Female 177 lb 7/15/2006 Pharmacist United States
Primary
Concomitant
Pneumonia Required Intervention 7/23/2006 68 Female 148 lb 7/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 54 Male 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 54 Male 1/25/2007 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/6/2006 31 Female 187 lb 12/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/5/2007 United Kingdom
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 6/15/2007 United States
Primary
Secondary
Concomitant
Mania Other Serious 6/1/2007 73 Male 6/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Female 133 lb 7/27/2007 Consumer United States
Primary
Concomitant
Intestinal Haemorrhage Hospitalization Male 54 lb 8/23/2007 Pharmacist United States
Primary
Concomitant
Stomatitis Other Serious 7/1/2007 Female 185 lb 8/29/2007 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 7/8/2007 Female 109 lb 8/30/2007 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 9/7/2007 55 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
Red Man Syndrome Other Serious 5/26/2006 69 Female 10/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Female 133 lb 11/2/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 1/1/2007 Female 133 lb 11/13/2007 Consumer United States
Primary
Concomitant
Extradural Haematoma Life Threatening 10/24/2007 42 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 10/24/2007 93 Male 179 lb 10/30/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/12/2007 75 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 2/1/2003 56 Male 12/18/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 11/14/2007 70 Female 146 lb 12/3/2007 Pharmacist United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Renal Injury Hospitalization 21 Male 3/5/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 1/18/2008 Male 265 lb 3/11/2008 Canada
Primary
Concomitant
Cholecystitis Hospitalization 4/13/2008 Female 137 lb 4/28/2008 United States
Primary
Concomitant
Cholecystitis Hospitalization 4/13/2008 Female 137 lb 5/5/2008 United States
Primary
Concomitant
Splenic Rupture Other Serious 2/12/2008 65 Female 159 lb 5/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Vomiting Other Serious 5/8/2008 76 Female 121 lb 6/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/24/2008 57 Male 366 lb 6/17/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/8/2007 61 Female 7/2/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/23/2008 82 Male 8/25/2008 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/9/2008 66 Female 125 lb 8/22/2008 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/23/2008 82 Male 9/16/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2008 54 Female 9/15/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2008 Female 235 lb 11/11/2008 Consumer United States
Primary
Concomitant
Haemorrhage Required Intervention 5/22/2008 Female 114 lb 6/24/2008 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 7/23/2008 82 Male 11/24/2008 Physician Japan
Primary
Secondary
Concomitant
Panniculitis Required Intervention 8/10/2008 41 Female 333 lb 8/28/2008 Pharmacist United States
Primary
Concomitant
Secondary Amyloidosis Other Serious 1/1/2008 Female 2/11/2009 Physician United States
Primary
Concomitant
Infection Other Serious 11/2/2008 Female 123 lb 3/24/2009 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/27/2009 52 Female 115 lb 6/9/2009 Pharmacist United States
Primary
Concomitant
Stent Occlusion Other Serious 6/20/2008 Male 189 lb 6/25/2009 Physician United States
Primary
Concomitant
Vaginal Haemorrhage Required Intervention 4/14/2009 44 Female 214 lb 4/15/2009 Pharmacist United States
Primary
Concomitant
Oesophageal Achalasia Hospitalization 6/8/2009 Female 149 lb 7/27/2009 Physician United States
Primary
Concomitant
Hepatocellular Injury Other Serious 7/10/2009 69 Female 8/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 8/5/2009 53 Female 287 lb 9/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 9/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 8/30/2009 41 Female 198 lb 10/13/2009 Other Health Professional Singapore
Primary
Concomitant
Oesophageal Achalasia Other Serious 6/8/2009 Female 149 lb 10/22/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 10/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/30/2009 Male 187 lb 9/11/2009 Pharmacist United States
Primary
Concomitant
Death Death Female 11/16/2009 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 54 Female 12/1/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 2/1/2008 84 Female 1/27/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 5/1/2003 Male 2/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 2/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 3/29/2005 Male 2/18/2010 Physician United States
Primary
Secondary
Concomitant
Rash Generalised Other Serious 2/1/2008 83 Female 137 lb 2/26/2010 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 Male 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 Male 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/1/2003 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 3/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 Male 3/17/2010 Physician United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/16/2010 49 Female 22 lb 1/18/2010 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 4/1/2003 Male 3/19/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 Male 3/26/2010 United States
Primary
Secondary
Concomitant
Microalbuminuria Other Serious 1/1/2009 77 4/8/2010 Physician Canada
Primary
Concomitant
Loss Of Consciousness Other Serious 1/14/2010 89 Female 4/9/2010 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 88 Female 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 10/1/2007 84 Female 4/13/2010 Lawyer United States
Primary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 4/14/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/19/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 4/20/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 4/22/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 4/26/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/15/2010 84 Female 139 lb 2/15/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/23/2010 57 Female 278 lb 2/25/2010 Pharmacist United States
Primary
Concomitant
Overdose Hospitalization 2/15/2010 84 Female 140 lb 2/16/2010 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/23/2010 57 Female 278 lb 2/23/2010 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/3/2010 50 Female 210 lb 3/4/2010 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 84 Male 5/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 84 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 84 Male 5/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 84 Male 5/12/2010 Other Health Professional
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/18/2010 79 Female 5/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Fatigue Other Serious 5/1/2010 82 Female 6/7/2010 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 6/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Coagulation Time Prolonged Female 118 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 6/28/2006 80 Male 8/2/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 8/26/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 1/1/2008 68 Male 242 lb 10/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 10/1/2007 84 Female 150 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations 11/9/2010 46 Female 11/12/2010 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 11/25/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 2/7/2008 68 Male 242 lb 12/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/1/2003 56 Male 12/23/2010 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 10/15/2010 54 Male 12/23/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 4/1/2003 79 Male 12/23/2010 United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious 12/1/2010 86 Male 209 lb 1/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Disability 12/1/2010 86 Male 209 lb 1/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Other Serious 1/1/2008 72 Male 214 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Microangiopathy Hospitalization 89 Female 188 lb 3/7/2011 Lawyer United States
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 4/1/2003 79 Male 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/6/2011 38 Female 6/24/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Bursitis Other Serious Female 6/28/2011 Physician United States
Primary
Secondary
Concomitant
Burning Sensation Other Serious Female 7/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Oropharyngeal Pain Hospitalization 4/1/2003 79 Male 7/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vulval Cellulitis Hospitalization 6/28/2011 63 Female 260 lb 7/26/2011 Physician Australia
Primary
Secondary
Concomitant
Anxiety Other Serious 6/13/2011 89 Female 7/27/2011 Other Health Professional United Kingdom
Primary
Concomitant
Vulval Cellulitis Hospitalization 6/22/2011 63 Female 260 lb 8/2/2011 Physician Australia
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 7/13/2009 77 Male 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 5/6/2011 38 Female 8/5/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Melaena Hospitalization 7/1/2011 77 Male 7/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious Female 8/16/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/15/2011 57 Female 176 lb Physician United States
Primary
Concomitant
Upper Limb Fracture Other Serious 9/1/2010 71 Female 9/7/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation Hospitalization 64 Female 9/16/2011 Consumer United States
Primary
Secondary
Concomitant
Head And Neck Cancer Hospitalization 8/1/2011 84 Male 9/20/2011 Consumer United States
Primary
Secondary
Concomitant
Dysphagia Other Serious 8/1/2011 84 Male 9/22/2011 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/3/2011 74 Male 159 lb 10/7/2011 Other Health Professional United Kingdom
Primary
Concomitant
Retroperitoneal Haemorrhage Death 5/6/2011 38 Female 10/11/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Areflexia Other Serious 58 Male 10/14/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Depressed Level Of Consciousness Hospitalization 58 Male 10/16/2011 Other Health Professional United States
Primary
Concomitant
Interacting

Drug Data