Rocuronium Bromide combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Hospitalization 1/21/2005 Male 185 lb 1/19/2006 Australia
Primary
Secondary
Concomitant
Drug Ineffective 11/25/2005 50 Male 2/15/2006 Other Health Professional Portugal
Primary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 4/24/2006 32 Female 8/11/2006 South Africa
Primary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Pulmonary Oedema Death 45 Female 2/1/2007 Physician Lebanon
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 45 Female 2/6/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urticaria Life Threatening 10/13/2006 26 Female 5/24/2007 Finland
Primary
Concomitant
Thrombocytopenia Death 7/17/2006 5 Female 44 lb 6/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 6/12/2007 10 Female 6/15/2007 United States
Primary
Secondary
Supraventricular Extrasystoles Other Serious 79 Female 110 lb 7/11/2007 Physician United States
Primary
Concomitant
Interacting
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Respiratory Failure Other Serious 62 201 lb 8/9/2007 Germany
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 62 Male 201 lb 8/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1 Female 13 lb 8/27/2007 United States
Primary
Secondary
Concomitant
Therapeutic Response Delayed Life Threatening 8/7/2007 39 Female 8/21/2007 Korea, Republic Of
Primary
Concomitant
Ventricular Tachycardia Other Serious 0 Female 12 lb 8/28/2007 United States
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 3/5/2007 36 Female 9/10/2007 Australia
Primary
Secondary
Ventricular Tachycardia Hospitalization 0 Female 12 lb 9/19/2007 Other Health Professional United States
Primary
Secondary
Myoclonus Hospitalization 2/19/2007 Female 10/23/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Death 1 Male 10/24/2007 Consumer United States
Primary
Secondary
Ventricular Fibrillation Other Serious 13 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 1 Female 11/7/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 11/9/2007 Physician New Zealand
Primary
Concomitant
Tachycardia Death 1 Male 11/8/2007 Consumer United States
Primary
Secondary
Tachycardia Death 1 Male 11/8/2007 United States
Primary
Secondary
Rhabdomyolysis Life Threatening 1 Male 9 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Myoclonus Hospitalization 2/19/2007 Female 11/19/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Depression Life Threatening 53 Female 128 lb 11/19/2007
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 2/19/2007 32 Female 11/15/2007 Australia
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 8/1/2007 69 Male 12/3/2007 Physician Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 12/18/2007 46 Female 121 lb 12/27/2007 Ecuador
Primary
Concomitant
Respiratory Depression Required Intervention 3/9/2007 11/27/2007 Pharmacist United States
Primary
Concomitant
Respiratory Depression Other Serious 53 Female 128 lb 1/18/2008 New Zealand
Primary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 69 Female 3/5/2008 Australia
Primary
Secondary
Concomitant
Hypertension Other Serious 69 Female 150 lb 3/28/2008 Australia
Primary
Concomitant
Interacting
Toxic Encephalopathy Hospitalization 49 Female 4/17/2008 Physician Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Life Threatening 35 Female 165 lb 5/21/2008 Other Health Professional Turkey
Primary
Concomitant
Rhabdomyolysis 4/17/2008 37 Male 5/20/2008 Japan
Primary
Concomitant
Hypoventilation 10/23/2007 71 Male 5/22/2008 Japan
Primary
Secondary
Concomitant
Tachycardia 5/10/2008 25 Female 5/28/2008 Belgium
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/17/2008 37 Male 5/28/2008 Japan
Primary
Secondary
Concomitant
Shock Other Serious 56 Female 192 lb 6/16/2008 Other Health Professional Portugal
Primary
Concomitant
Vomiting Other Serious 5/29/2008 Female 6/17/2008 Physician Japan
Primary
Concomitant
Hypoventilation 10/23/2007 71 Male 6/13/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 5/29/2008 Female 97 lb 6/23/2008 Physician Japan
Primary
Concomitant
Sepsis Death 3/26/2007 66 Male 176 lb 6/27/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 3/11/2008 76 Female 6/24/2008 Japan
Primary
Concomitant
Anaphylactic Reaction Hospitalization 6/17/2008 Female 6/30/2008 Pharmacist Japan
Primary
Secondary
Vomiting Other Serious 5/29/2008 Female 97 lb 6/30/2008 Physician Japan
Primary
Concomitant
Tachycardia 5/10/2008 25 Female 6/26/2008 Belgium
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/3/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyperthermia Malignant Other Serious Male 132 lb 7/8/2008 Romania
Primary
Concomitant
Vomiting Other Serious 5/29/2008 Female 97 lb 7/9/2008 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Hospitalization 6/17/2008 Female 7/9/2008 Pharmacist Japan
Primary
Secondary
Anaphylactic Reaction Hospitalization 6/17/2008 72 Female 84 lb 7/21/2008 Pharmacist Japan
Primary
Secondary
Tachycardia 5/10/2008 25 Female 7/16/2008 Physician Belgium
Primary
Concomitant
Anaphylactic Reaction Hospitalization 6/17/2008 72 Female 84 lb 8/18/2008 Pharmacist Japan
Primary
Secondary
Laryngeal Oedema Hospitalization 7/30/2008 7 Male 8/12/2008 Other Health Professional Japan
Primary
Secondary
Spinal Fracture Other Serious 12/4/2006 Female 119 lb 8/29/2008 Physician United States
Primary
Concomitant
Laryngeal Oedema Hospitalization 7/30/2008 7 Male 9/2/2008 Japan
Primary
Secondary
Troponin Increased Hospitalization 49 Female 9/19/2008 Canada
Primary
Secondary
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/26/2008 83 Male 139 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 9/16/2008 2 Female 37 lb 10/3/2008 Physician United States
Primary
Concomitant
Urticaria Life Threatening 9/29/2008 63 Male 10/7/2008 Finland
Primary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/17/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/5/2008 Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 3/11/2008 76 Female 11/7/2008 Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 47 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Arteriospasm Coronary Other Serious 59 Male 152 lb 11/18/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/20/2008 Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 8/26/2008 83 Male 139 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/25/2008 79 Male 134 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Arteriospasm Coronary Other Serious 59 Male 152 lb 12/2/2008 Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 11/18/2008 77 Female 185 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Other Serious 60 Female 12/4/2008 Physician Japan
Primary
Concomitant
Myoclonic Epilepsy Other Serious 10/10/2008 69 Female 137 lb 11/26/2008 Pharmacist United States
Primary
Secondary
Concomitant
Angle Closure Glaucoma Other Serious 59 Male 12/10/2008 Other Health Professional Japan
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 60 Female 12/10/2008 Physician Japan
Primary
Concomitant
Urticaria 11/25/2008 3 Female 12/4/2008 Japan
Primary
Concomitant
Urticaria 11/25/2008 3 Female 12/11/2008 Japan
Primary
Secondary
Angle Closure Glaucoma Other Serious 59 Male 12/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Wernicke-korsakoff Syndrome Hospitalization 11/13/2008 69 Male 160 lb 12/13/2008 Pharmacist United States
Primary
Concomitant
Drug Ineffective Hospitalization 2/6/2008 37 Female 240 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 2/8/2008 54 Male 146 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 2/8/2008 20 Female 218 lb 12/11/2008 Other Health Professional United States
Primary
Concomitant
Humerus Fracture 11/1/2008 52 Female 12/29/2008 Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 1/13/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Somnolence Other Serious 61 Female 143 lb 1/8/2009 Other Health Professional Brazil
Primary
Concomitant
Extrasystoles Other Serious 1/13/2009 21 Female 121 lb 1/22/2009 Venezuela
Primary
Concomitant
Extrasystoles Other Serious 1/13/2009 Female 121 lb 1/29/2009 Venezuela
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/13/2009 Female 1/30/2009 Physician Venezuela
Primary
Concomitant
Stress Cardiomyopathy Other Serious 60 Female 95 lb 2/10/2009 Other Health Professional Japan
Primary
Secondary
Threatened Labour Hospitalization 6/22/2008 40 Female 2/6/2009 Japan
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 60 Female 95 lb 2/23/2009 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 3/5/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 2/16/2009 17 Female 3/5/2009 Other Health Professional Japan
Primary
Concomitant
Tachycardia Hospitalization 56 Male 3/10/2009 United States
Primary
Concomitant
Wheelchair User Hospitalization 2/16/2009 17 Female 3/19/2009 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 3/31/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hyperthermia Death 26 Male 3/31/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Tachycardia Life Threatening 61 Female 143 lb 4/6/2009
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 4/10/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 60 Male 4/13/2009
Primary
Secondary
Hyperthermia Death 26 Male 4/13/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Tachycardia Other Serious 2/13/2009 Female 198 lb 5/4/2009 Other Health Professional Montenegro
Primary
Concomitant
Rhabdomyolysis Hospitalization 12/4/2008 58 Male 5/6/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 11/17/2008 59 Female 198 lb 5/6/2009 Other Health Professional Switzerland
Primary
Concomitant
Oliguria Other Serious Female 5/1/2009 Physician Japan
Primary
Concomitant
Oliguria Other Serious Female 5/1/2009 Physician Japan
Primary
Concomitant
Cardiac Arrest Life Threatening 11/17/2008 59 Female 198 lb 5/14/2009 Other Health Professional Switzerland
Primary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 68 Male 143 lb 5/20/2009 Other Health Professional Japan
Primary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 68 Male 143 lb 5/29/2009 Other Health Professional Japan
Primary
Concomitant
Paralysis Hospitalization 2/16/2009 17 Female 5/28/2009 Japan
Primary
Concomitant
Heart Rate Decreased Other Serious 5/26/2009 Female 6/4/2009 Other Health Professional Japan
Primary
Secondary
Rhabdomyolysis Other Serious Male 6/5/2009 Other Health Professional Japan
Primary
Secondary
Respiratory Depression Life Threatening 3/19/2009 Male 95 lb 6/22/2009 Physician Japan
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 12/1/2008 39 Female 7/7/2009 Australia
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 3/23/2007 60 Male 7/23/2009
Primary
Secondary
Lung Disorder Hospitalization 12/1/2008 38 Female 104 lb 7/31/2009 Physician Japan
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged 8/22/2008 40 Female 7/23/2009 Japan
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 12/1/2008 38 Female 104 lb 8/12/2009 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 8/10/2009 Japan
Primary
Secondary
Rhabdomyolysis Hospitalization 4/1/2007 37 Male 8/21/2009 Other Health Professional Japan
Primary
Secondary
Drug Interaction Other Serious 33 Female 176 lb 8/27/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 12/1/2008 38 Female 104 lb 9/11/2009 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 135 lb 9/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tracheomalacia Other Serious 1 Female 22 lb 10/5/2009 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Other Serious 35 Female 106 lb 10/6/2009 Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 80 Female 121 lb 10/15/2009 Japan
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 79 Female 10/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tracheomalacia Other Serious 1 Female 22 lb 10/16/2009 Japan
Primary
Concomitant
Hepatitis Toxic Other Serious 9/28/2009 43 Female 10/19/2009 Physician Turkey
Primary
Concomitant
Status Epilepticus Other Serious 35 Female 106 lb 10/19/2009 Japan
Primary
Concomitant
Ventricular Arrhythmia Other Serious 80 Female 121 lb 10/23/2009 Japan
Primary
Secondary
Concomitant
Tracheomalacia Other Serious 1 Female 22 lb 10/30/2009 Japan
Primary
Concomitant
Salivary Gland Enlargement Other Serious 67 Female 11/5/2009 Physician Japan
Primary
Concomitant
Torsade De Pointes Required Intervention 80 Female 121 lb 10/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 3/25/2009 Female 106 lb 11/5/2009 Japan
Primary
Concomitant

Drug Data