Ritonavir combined with Tmc114

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Decreased Hospitalization 10/19/2005 Male 130 lb 1/12/2006 Switzerland
Primary
Concomitant
Ventricular Dysfunction Life Threatening 8/30/2005 Male 139 lb 2/8/2006 United Kingdom
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/2/2005 54 Male 2/24/2006 Physician France
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/19/2005 Male 130 lb 3/16/2006 Switzerland
Primary
Concomitant
Pyrexia Other Serious 4/1/2002 Male 139 lb 3/27/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 12/21/2005 Male 161 lb 3/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2005 Male 130 lb 4/13/2006 Switzerland
Primary
Concomitant
Melanocytic Naevus Hospitalization 10/19/2005 Male 130 lb 5/11/2006 Switzerland
Primary
Concomitant
Urine Flow Decreased Hospitalization 4/4/2006 Male 146 lb 6/30/2006 Belgium
Primary
Secondary
Concomitant
Urine Flow Decreased Hospitalization 4/4/2006 Male 146 lb 7/3/2006 United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/17/2005 Male 130 lb 8/25/2006 Switzerland
Primary
Concomitant
Renal Failure Acute Life Threatening 5/15/2006 Male 205 lb 9/8/2006 Physician United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 1/18/2007 Male 143 lb 2/9/2007 Physician Brazil
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 1/10/2007 Male 132 lb 2/9/2007 Physician Mexico
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 7/18/2006 Female 158 lb 2/13/2007 Physician Poland
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious 11/8/2006 Male 165 lb 2/16/2007 Physician Panama
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 2/16/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 9/3/2006 49 Male 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Cholecystectomy Other Serious 8/24/2006 Male 172 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 2/23/2007 Physician Mexico
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 8/24/2006 Male 172 lb 3/2/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2007 16 Male 3/2/2007 Physician France
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 6/8/2006 Male 169 lb 3/2/2007 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/4/2006 Male 162 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 7/18/2006 Female 158 lb 3/5/2007 Physician Poland
Primary
Secondary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 1/29/2007 Male 162 lb 3/5/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/27/2007 Male 168 lb 3/8/2007 Physician United States
Primary
Secondary
Concomitant
Severe Acute Respiratory Syndrome Other Serious 2/27/2007 Male 168 lb 3/13/2007 Physician United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 3/14/2007 Physician Mexico
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 3/19/2007 Physician Australia
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/2/2006 Male 192 lb 3/20/2007 Physician Belgium
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/18/2007 Male 143 lb 3/23/2007 Physician Brazil
Primary
Secondary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 1/29/2007 Male 162 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 5/10/2006 Male 110 lb 3/26/2007 Physician Argentina
Primary
Secondary
Concomitant
Costochondritis Hospitalization 10/2/2006 Male 184 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Encephalitis Cytomegalovirus Hospitalization 10/6/2006 Male 205 lb 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 10/3/2006 Male 152 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 11/16/2006 Male 134 lb 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Life Threatening 8/29/2006 Male 117 lb 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 6/2/2006 Male 192 lb 3/26/2007 Physician Belgium
Primary
Secondary
Concomitant
Partial Seizures Other Serious 9/30/2006 Male 132 lb 3/26/2007 Physician Mexico
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/2/2006 Female 97 lb 3/26/2007 Physician Argentina
Primary
Secondary
Concomitant
Interacting
Pancreatic Insufficiency Life Threatening 6/5/2006 Male 110 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/23/2006 Female 46 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Relapsing Life Threatening 11/30/2006 42 Male 3/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis Hospitalization 7/7/2006 Male 151 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 8/12/2006 Male 3/26/2007 Physician Argentina
Primary
Secondary
Concomitant
Cachexia Death 8/22/2006 Male 216 lb 3/26/2007 Physician Canada
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 6/17/2006 Male 139 lb 3/26/2007 Physician Australia
Primary
Secondary
Concomitant
Renal Impairment Other Serious 7/31/2006 Male 110 lb 3/26/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Mycobacterium Avium Complex Infection Hospitalization 6/12/2006 Male 131 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/15/2006 Male 205 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 4/4/2006 Female 127 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Anaemia Other Serious 8/30/2006 Male 158 lb 3/26/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2006 Male 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 7/16/2006 Male 161 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 9/15/2006 Male 56 lb 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 9/12/2006 Male 163 lb 3/26/2007 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 12/10/2006 Male 218 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 3/26/2007 Physician South Africa
Primary
Secondary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Interacting
Pyrexia Other Serious 9/12/2006 Male 214 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Shock Hospitalization 11/23/2006 Female 90 lb 3/26/2007 Physician Panama
Primary
Secondary
Concomitant
Meningitis Hospitalization 8/17/2006 Male 156 lb 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 8/29/2006 Male 117 lb 3/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/18/2007 Male 143 lb 3/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 2/1/2007 Male 181 lb 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 1/10/2007 Male 132 lb 4/10/2007 Physician Mexico
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/18/2007 Male 143 lb 4/10/2007 Physician Brazil
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 2/27/2007 Male 95 lb 4/11/2007 Physician Singapore
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 4/16/2007 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 5/10/2006 Male 110 lb 4/18/2007 Physician Argentina
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 4/19/2007 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 166 lb 4/20/2007 Physician Chile
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/18/2007 Male 143 lb 4/24/2007 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/20/2006 Male 4/25/2007 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 4/26/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/1/2007 Male 181 lb 4/27/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/27/2007 Male 168 lb 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Nervous System Disorder Hospitalization 2/27/2007 Male 95 lb 5/2/2007 Physician Singapore
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 10/9/2006 Female 167 lb 5/2/2007 Physician South Africa
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 166 lb 5/2/2007 Physician Chile
Primary
Secondary
Concomitant
Cytomegalovirus Myocarditis Other Serious 1/23/2007 Female 119 lb 5/4/2007 Physician Italy
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 3/28/2007 Male 5/7/2007 Physician Thailand
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 12/13/2006 Male 5/16/2007 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Life Threatening 2/25/2007 Male 5/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 166 lb 5/21/2007 Physician Chile
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/3/2006 Female 152 lb 5/21/2007 Physician Sweden
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/3/2007 Male 147 lb 5/21/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/2/2006 Male 5/25/2007 Physician Spain
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 5/28/2007 Male 187 lb 6/1/2007 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Hospitalization 7/10/2006 Female 152 lb 6/1/2007 Physician Sweden
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 5/9/2006 60 Male 146 lb 6/7/2007 Physician Belgium
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/23/2007 Female 119 lb 6/7/2007 Physician Italy
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 5/28/2007 Male 187 lb 6/7/2007 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 166 lb 6/8/2007 Physician Chile
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization Male 150 lb 6/11/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 5/16/2007 Female 71 lb 6/11/2007 Physician Brazil
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 5/3/2007 Female 110 lb 6/11/2007 Physician Argentina
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/3/2007 Male 147 lb 6/11/2007 Physician United States
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 5/16/2007 Female 71 lb 6/25/2007 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Other Serious 6/14/2007 Male 6/25/2007 Physician Canada
Primary
Secondary
Concomitant
Blood Triglycerides Increased Other Serious 11/8/2006 Male 165 lb 6/25/2007 Physician Panama
Primary
Secondary
Concomitant
Percutaneous Coronary Intervention Hospitalization 1/1/2007 Male 201 lb 6/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 5/16/2007 Female 71 lb 6/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 6/27/2007 Physician United States
Primary
Secondary
Concomitant
Intermittent Claudication Hospitalization 1/1/2007 Male 201 lb 7/3/2007 Physician Belgium
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 6/14/2007 Male 7/3/2007 Physician Canada
Primary
Secondary
Concomitant
Idiopathic Urticaria Hospitalization 6/22/2007 Male 7/6/2007 Physician Italy
Primary
Secondary
Concomitant
Pancreatitis Life Threatening 6/13/2007 Male 7/6/2007 Physician Canada
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 5/16/2007 Female 71 lb 7/9/2007 Physician Brazil
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/25/2006 Male 7/9/2007 Physician Brazil
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 146 lb 7/16/2007 Physician Chile
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 Female 175 lb 7/16/2007 Physician United States
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 4/10/2007 Male 146 lb 7/16/2007 Physician Chile
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious 5/16/2007 Female 71 lb 7/20/2007 Physician Brazil
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 5/3/2007 Female 110 lb 7/27/2007 Physician Argentina
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 146 lb 7/30/2007 Physician Chile
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 3/28/2007 Male 7/30/2007 Physician Thailand
Primary
Secondary
Concomitant
Brain Stem Haemorrhage Other Serious 5/27/2007 Male 223 lb 7/31/2007 Physician Australia
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 7/31/2007 Physician United States
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/21/2007 49 Male 8/2/2007 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2007 Male 146 lb 8/3/2007 Physician Chile
Primary
Secondary
Concomitant
Renal Failure Life Threatening 7/5/2007 Female 175 lb 8/3/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 8/13/2007 Male 117 lb 8/16/2007 Physician Brazil
Primary
Secondary
Concomitant
Jaundice Hospitalization 6/1/2007 Male 132 lb 8/16/2007 Physician Italy
Primary
Secondary
Concomitant
Death Death 8/13/2007 Male 117 lb 8/23/2007 Physician Brazil
Primary
Secondary
Concomitant
Jaundice Hospitalization 7/23/2007 Male 132 lb 8/24/2007 Physician Italy
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 5/28/2007 Male 187 lb 8/24/2007 Physician Australia
Primary
Secondary
Concomitant
Death Death 8/9/2007 Male 117 lb 8/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/15/2007 Female 209 lb 8/28/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 5/28/2007 Male 187 lb 9/4/2007 Physician Australia
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 5/8/2007 Male 146 lb 9/4/2007 Physician Chile
Primary
Secondary
Concomitant
Cardiogenic Shock Hospitalization 8/13/2007 Male 117 lb 9/5/2007 Physician Brazil
Primary
Secondary
Concomitant
Coronary Arterial Stent Insertion Hospitalization 1/29/2007 Male 162 lb 9/10/2007 Physician United States
Primary
Secondary
Concomitant
Arteriosclerosis Hospitalization 7/1/2006 Male 201 lb 9/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2007 Male 132 lb 9/11/2007 Physician Italy
Primary
Secondary
Concomitant
Vaginal Haemorrhage Life Threatening 8/7/2007 Female 9/18/2007 Physician Brazil
Primary
Secondary
Concomitant
Arteriosclerosis Hospitalization 7/1/2006 Male 201 lb 9/20/2007 Physician Belgium
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/7/2007 Female 9/24/2007 Physician Brazil
Primary
Secondary
Concomitant
Disorientation Hospitalization 7/10/2005 Male 159 lb 9/27/2007 Physician Austria
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/17/2005 Male 130 lb 9/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Hypertension Other Serious 1/12/2004 Male 9/27/2007 Physician France
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 2/10/2004 Male 9/28/2007 Physician France
Primary
Secondary
Concomitant

Drug Data