Ritonavir Soft Gelatin Capsules combined with Tmc114

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Lung Disorder Other Serious 12/6/2005 Male 138 lb 1/13/2006 Ireland
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/9/2006 United States
Primary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 2/21/2006 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 2/23/2006 United States
Primary
Concomitant
Death Death 2/3/2006 Male 127 lb 3/20/2006 United States
Primary
Concomitant
Renal Failure Acute Life Threatening 6/9/2005 Male 170 lb 3/22/2006 United States
Primary
Concomitant
Tuberculosis Hospitalization 3/8/2006 Male 289 lb 3/27/2006 Ireland
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 3/28/2006 France
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/13/2006 France
Primary
Concomitant
Vomiting Life Threatening 3/3/2006 Male 131 lb 4/20/2006 Ireland
Primary
Concomitant
Vomiting Life Threatening 3/3/2006 Male 131 lb 4/24/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 4/25/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 5/3/2006 United States
Primary
Concomitant
Pneumonia Life Threatening 6/9/2005 Male 170 lb 5/12/2006 United States
Primary
Concomitant
Micrognathia Congenital Anomaly 10/14/2005 Male 7 lb 5/17/2006 United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 5/18/2006 United States
Primary
Concomitant
Ulcer Life Threatening 5/11/2006 Male 128 lb 5/23/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 6/7/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 6/15/2006 Ireland
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 6/28/2006 Ireland
Primary
Concomitant
Respiratory Failure Other Serious 12/6/2005 Male 138 lb 6/29/2006 Ireland
Primary
Concomitant
Respiratory Failure Other Serious 12/6/2005 Male 138 lb 6/29/2006 Ireland
Primary
Concomitant
Blood Creatine Phosphokinase Mb Increased Hospitalization 6/21/2006 Male 171 lb 7/19/2006 Ireland
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Hospitalization 3/11/2006 Male 8/10/2006 United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 5/11/2006 Male 128 lb 8/17/2006 Ireland
Primary
Concomitant
Subdural Haematoma Hospitalization 7/21/2006 Male 8/31/2006 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 9/15/2006 Ireland
Primary
Concomitant
Respiratory Failure Other Serious 12/6/2005 Male 138 lb 9/27/2006 Ireland
Primary
Concomitant
Traumatic Brain Injury Hospitalization 7/16/2006 Male 10/12/2006 Ireland
Primary
Concomitant
Osteonecrosis Hospitalization 6/23/2005 Female 148 lb 10/19/2006 Ireland
Primary
Concomitant
Respiratory Failure Other Serious 12/6/2005 Male 138 lb 10/19/2006 Ireland
Primary
Concomitant
Sepsis Life Threatening 3/3/2006 Male 131 lb 10/19/2006 Ireland
Primary
Concomitant
Costochondritis Hospitalization 10/2/2006 Male 184 lb 11/17/2006 Ireland
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization Male 112 lb 11/28/2006 Belgium
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 9/30/2006 Male 132 lb 11/29/2006 Ireland
Primary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 12/4/2006 Ireland
Primary
Concomitant
Shock Life Threatening 11/23/2006 Female 90 lb 12/5/2006 Ireland
Primary
Concomitant
Cerebrovascular Accident Life Threatening 12/8/2005 Male 132 lb 12/7/2006 France
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 12/31/2005 Male 216 lb 12/20/2006
Primary
Concomitant
Multiple Drug Overdose Life Threatening 9/30/2006 Male 176 lb 12/20/2006 Ireland
Primary
Concomitant
Interacting
Sepsis Life Threatening 3/3/2006 Male 131 lb 12/20/2006 Ireland
Primary
Concomitant
Shock Life Threatening 11/23/2006 Female 90 lb 12/20/2006 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 1/11/2007 Ireland
Primary
Concomitant
Disorientation Other Serious 12/12/2006 Male 249 lb 1/22/2007
Primary
Concomitant
Partial Seizures Hospitalization 9/30/2006 Male 132 lb 1/27/2007 Ireland
Primary
Concomitant
Disorientation Other Serious 12/12/2006 Male 249 lb 3/5/2007
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 7/18/2006 Female 158 lb 3/15/2007 Ireland
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/12/2006 Male 249 lb 4/24/2007
Primary
Concomitant
Immune Reconstitution Syndrome Hospitalization 7/18/2006 Female 158 lb 4/25/2007 Ireland
Primary
Concomitant
Pneumonia Cytomegaloviral Hospitalization 4/15/2005 Male 185 lb 5/17/2007 United States
Primary
Concomitant
Brain Stem Haemorrhage Other Serious 5/27/2007 Male 223 lb 8/7/2007 Australia
Primary
Concomitant
Death Death 8/13/2007 Male 117 lb 8/21/2007 Brazil
Primary
Concomitant
Death Hospitalization 8/9/2007 Male 117 lb 9/5/2007 Brazil
Primary
Concomitant
Cardiogenic Shock Death 8/13/2007 Male 117 lb 9/18/2007 Brazil
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 8/7/2007 Female 9/21/2007 Ireland
Primary
Concomitant
Squamous Cell Carcinoma Life Threatening 9/28/2007 Male 198 lb 10/9/2007 Ireland
Primary
Concomitant
Septic Shock Life Threatening 8/7/2007 Female 10/12/2007 Brazil
Primary
Concomitant
Anal Cancer Life Threatening 9/28/2007 Male 198 lb 10/23/2007 Ireland
Primary
Concomitant
Brain Stem Haemorrhage Other Serious 5/27/2007 Male 223 lb 11/8/2007 Australia
Primary
Concomitant
Anal Cancer Life Threatening 9/21/2007 Male 198 lb 11/14/2007 Ireland
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 8/7/2007 Female 150 lb 11/16/2007 Brazil
Primary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 1/28/2008 Ireland
Primary
Concomitant
Thrombocytopenia Life Threatening 7/30/2004 Female 2/21/2008 Ireland
Primary
Concomitant
Blood Creatinine Increased Life Threatening 5/3/2007 Male 147 lb 3/7/2008 Ireland
Primary
Concomitant
Osteonecrosis Hospitalization 10/8/2007 Male 154 lb 4/2/2008 Ireland
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Life Threatening Male 4/3/2008 Ireland
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 2/28/2008 Male 172 lb 4/4/2008 Mexico
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 4/4/2008 Ireland
Primary
Concomitant
Vomiting Hospitalization 3/31/2005 Male 97 lb 4/9/2008 France
Primary
Concomitant
Thrombocytopenic Purpura Other Serious 2/25/2008 Male 172 lb 4/17/2008
Primary
Concomitant
Spinal Cord Compression Hospitalization 11/23/2006 Male 123 lb 6/5/2008 France
Primary
Concomitant
Anal Cancer Life Threatening 9/28/2007 Male 198 lb 6/6/2008 Ireland
Primary
Concomitant
Thrombocytopenia Other Serious 2/25/2008 Male 172 lb 6/6/2008
Primary
Concomitant
Osteonecrosis Hospitalization 6/23/2005 Female 148 lb 6/6/2008 Ireland
Primary
Concomitant
Diabetic Ketoacidosis Life Threatening 4/13/2008 Male 157 lb 6/13/2008 Ireland
Primary
Concomitant
Thrombocytopenia Other Serious 2/25/2008 Male 183 lb 6/13/2008
Primary
Concomitant
Renal Failure Other Serious 2/27/2007 Male 168 lb 6/16/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 2/27/2007 Male 176 lb 7/3/2008 Brazil
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 2/27/2007 Male 176 lb 7/17/2008 Brazil
Primary
Concomitant
Intestinal Polyp Hospitalization 2/29/2008 Male 188 lb 7/17/2008 Brazil
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 7/21/2008 United States
Primary
Concomitant
Death Hospitalization 11/1/2007 Male 106 lb 7/22/2008 Ireland
Primary
Concomitant
Atrial Fibrillation Hospitalization 10/3/2007 Male 157 lb 7/31/2008 Brazil
Primary
Concomitant
Atrial Flutter Hospitalization 7/4/2007 Male 8/1/2008 Ireland
Primary
Concomitant
Hypokalaemia Life Threatening 4/22/2008 Male 8/6/2008 Belgium
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 2/27/2007 Male 176 lb 8/6/2008 Brazil
Primary
Concomitant
Depression Hospitalization 7/18/2008 Male 163 lb 8/7/2008 Ireland
Primary
Concomitant
Malnutrition Life Threatening 10/8/2007 Male 172 lb 8/8/2008 France
Primary
Concomitant
Renal Failure Hospitalization 8/29/2006 Male 172 lb 8/22/2008 Ireland
Primary
Concomitant
Myocardial Infarction Death 5/2/2008 Male 212 lb 8/29/2008 Ireland
Primary
Concomitant
Osteonecrosis Hospitalization 8/1/2008 Male 243 lb 9/4/2008 France
Primary
Concomitant
Calculus Urinary Hospitalization 8/27/2008 Male 157 lb 9/5/2008 Ireland
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 9/10/2008 Brazil
Primary
Concomitant
Pancytopenia Life Threatening 10/30/2006 Male 157 lb 9/17/2008 Brazil
Primary
Concomitant
Renal Failure Hospitalization 8/29/2006 Male 172 lb 9/18/2008 Ireland
Primary
Concomitant
Shock Hospitalization 11/23/2006 Female 90 lb 9/18/2008 Ireland
Primary
Concomitant
Pyrexia Life Threatening 9/1/2006 Male 167 lb 9/25/2008 Ireland
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 9/25/2008 United States
Primary
Concomitant
Pancytopenia Life Threatening 10/30/2006 Male 157 lb 9/30/2008 Brazil
Primary
Concomitant
Thyroiditis Acute Hospitalization 2/25/2007 Male 179 lb 10/2/2008 Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 9/27/2008 Male 120 lb 10/3/2008 Ireland
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 10/6/2008 Brazil
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 10/6/2008 United States
Primary
Concomitant
Deafness Unilateral Hospitalization 7/4/2006 Male 165 lb 10/14/2008 Australia
Primary
Concomitant
Tachycardia Hospitalization 7/7/2008 Male 159 lb 10/14/2008 Ireland
Primary
Concomitant
Thrombocytopenia Life Threatening 9/27/2008 Male 120 lb 10/21/2008 Ireland
Primary
Concomitant
Intestinal Polyp Hospitalization 2/29/2008 Male 188 lb 10/24/2008 Brazil
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 2/27/2007 Male 176 lb 10/29/2008 Brazil
Primary
Concomitant
Pneumonia Hospitalization 7/7/2008 Male 159 lb 10/30/2008 Ireland
Primary
Concomitant
Haemorrhagic Stroke Hospitalization 2/27/2007 Male 176 lb 11/5/2008 Brazil
Primary
Concomitant
Osteonecrosis Hospitalization 8/1/2008 Male 243 lb 11/12/2008 France
Primary
Concomitant
Thyroiditis Acute Hospitalization 2/25/2007 Male 179 lb 11/26/2008 Ireland
Primary
Concomitant
Calculus Urinary Hospitalization 8/27/2008 Male 157 lb 11/26/2008 Ireland
Primary
Concomitant
Dermatitis Bullous Life Threatening 11/18/2008 Male 132 lb 12/1/2008 Ireland
Primary
Concomitant
Dermatitis Bullous Life Threatening 11/18/2008 Male 132 lb 12/2/2008 Ireland
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 11/22/2008 Female 139 lb 12/5/2008 Guatemala
Primary
Concomitant
Secondary Syphilis Life Threatening 11/18/2008 Male 132 lb 12/15/2008 Ireland
Primary
Concomitant
Vulval Ulceration Hospitalization 8/12/2008 Female 220 lb 12/17/2008 United Kingdom
Primary
Concomitant
Secondary Syphilis Life Threatening 11/18/2008 Male 132 lb 12/22/2008 Ireland
Primary
Concomitant
Secondary Syphilis Life Threatening 11/18/2008 Male 132 lb 12/23/2008 Ireland
Primary
Concomitant
Pyrexia Hospitalization 10/7/2008 Male 176 lb 12/26/2008 Ireland
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 12/30/2008 United States
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 1/7/2009 United States
Primary
Concomitant
Histoplasmosis Hospitalization 10/7/2008 Male 176 lb 1/14/2009 Ireland
Primary
Concomitant
Death Other Serious 12/1/2008 Male 117 lb 1/16/2009 Ireland
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 1/21/2009 Brazil
Primary
Concomitant
Retinal Detachment Hospitalization 11/5/2008 Male 139 lb 1/23/2009 Germany
Primary
Concomitant
Anaemia Other Serious 12/1/2008 Male 117 lb 1/28/2009 Ireland
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 2/11/2009 Brazil
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 2/11/2009 United States
Primary
Concomitant
Retinal Detachment Hospitalization 8/1/2008 Male 139 lb 2/18/2009 Germany
Primary
Concomitant
Varices Oesophageal Life Threatening 5/27/2008 Female 116 lb 2/26/2009 Brazil
Primary
Concomitant
Sepsis Hospitalization 7/1/2006 Male 171 lb 3/5/2009 United States
Primary
Concomitant
Anaemia Other Serious 12/1/2008 Male 117 lb 3/10/2009 Ireland
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 5/27/2008 Female 116 lb 3/13/2009 Brazil
Primary
Concomitant
Retinal Detachment Hospitalization 8/1/2008 Male 139 lb 3/19/2009 Germany
Primary
Concomitant
Sinus Bradycardia Hospitalization 2/16/2009 Male 126 lb 3/19/2009 Ireland
Primary
Concomitant
Osteoporotic Fracture Hospitalization 2/7/2009 Male 143 lb 3/27/2009 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 3/27/2009 Ireland
Primary
Concomitant
Osteonecrosis Disability 1/29/2009 Male 159 lb 4/1/2009 Ireland
Primary
Concomitant
Sinus Bradycardia Life Threatening 2/16/2009 Male 126 lb 4/1/2009 Ireland
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2009 Male 143 lb 4/2/2009 Ireland
Primary
Concomitant
Anaemia Other Serious 12/1/2008 Male 117 lb 4/8/2009 Ireland
Primary
Concomitant
Osteonecrosis Disability 1/29/2009 Male 159 lb 5/4/2009 Ireland
Primary
Concomitant
Hepatitis Life Threatening 2/16/2009 Male 128 lb 5/12/2009 Ireland
Primary
Concomitant
Pyrexia Hospitalization 4/28/2009 Male 110 lb 5/21/2009
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/19/2009 Male 5/28/2009
Primary
Concomitant

Drug Data